건설업 근로자의 직무스트레스가 건설공사의 하자에 미치는 영향

심민영,박해천,이경훈,조상훈 대한안전경영과학회 2009 대한안전경영과학회 학술대회논문집 Vol.2009 No.1

당뇨병 환자의 우울증상과 스트레스 대처방식 : 류마티스 관절염 환자 및 건강 대조군과 비교

심민영,연규월,김하경,김영철,홍영선,이지수,이정희,류정화,하창윤,김지민,성유미,김수인,임원정 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.5

Objectives : This study investigated how diabetes mellitus (DM) and depressive symptoms are related, and differed in terms of coping strategies. In addition, we compared those findings with rheumatoid arthritis (RA) patients. Methods : 80 DM patients, 45 RA patients and 77 healthy subjects completed the Beck depression inventory (BDI) and the Korean version of the ways of coping checklist. Results : BDI scores of depressed DM patients were significantly higher than healthy subjects (p<0.01) but not Significantly with depressed RA patients. Both scores of active (p<0.01) and passive coping (p<0.05) in DM patients were significantly lower than healthy subjects (p<0.01), and the scores of wishful thinking of DM patients were significantly lower than RA patients (p<0.01). BDI scores of DM patients were significantly correlated with the number of complications and the scores of problem-focused coping (p<0.05). In the hierarchical regression analysis, even after controlling for clinical Characteristics, coping strategies altogether could account for 31.0% of the variance of the depressive symptoms in DM patients significantly (p<0.01). Conclusion : DM patients showed significantly higher depression rate than healthy subjects but not than RA patients. In DM patients, insufficient coping strategies could explain substantial portions of depressive symptoms. Therefore, enhancing healthier coping strategies in addition to prevent medical complications might lessen depressive symptoms experienced by DM patients.

정신분열병 환자에서 푸마르산 쿠에티아핀 서방정 교체 후의 임상적 이득과 주관적 안녕감 변화: 비중재, 관찰 연구 (CLIMAX Study)

심민영,최영락,신동환,김원,이정구,이요한,김은영,강석훈,유소영 대한정신약물학회 2011 대한정신약물학회지 Vol.22 No.3

Objective The aim of this study was to demonstrate changes of clinical benefit and subjective wellbeing after once-daily extended release quetiapine furmate (quetiapine XR) in patients with schizophrenia. Methods In a naturalistic, observational, and multicentric study, 1,494 patients with schizophrenia who switched to quetiapine XR (flexible dosing) due to insufficient efficacy or intolerance were recruited. Clinical Global Impressions-Clinical Benefit (CGI-CB), CGI-Severity (CGI-S), CGI-Improvement (CGI-I) and Subjective Wellbeing under Neuroleptic Treatment Scale (SWN-K) were assessed at baseline and after 8 weeks treatment. We also examined factors related to changes of CGI-CB and SWN-K scores using linear regression analysis. Results Among 1,494 patients, 1,342 patients (89.8%) completed this study and 1,204 patients (80.6%) without protocol violation were included in the analysis. The mean dose of quetiapine XR was 416.9±205.8 mg/day at the initiation and continuously increased to 591.6±228.3 mg/day until week 5. At the endpoint, the mean dose of quetiapine XR was 580.24±382.24 mg/day. Both CGI-CB and CGI-S scores were significantly decreased after 8 weeks (both p<0.0001) and 745 patients (61.9%) achieved clinical benefit. Mean CGI-I scores were 2.49±0.80 and the response rate defined as CGI-I≤2 was 51.6%. Subjective wellbeing scores were increased after 8weeks (p<0.0001). Improvements of CGI-CB and subjective wellbeing were associated with quetiapine XR dosages as well as age and baseline scores. Conclusion After switching to quetiapine XR, 61.9% of patients with schizophrenia who had a history of unsatisfactory treatment (efficacy or tolerance) showed clinical benefit and subjective wellbeing was significantly increased. Regarding that dosages of quetiapine XR were associated with improvements of clinical benefit and subjective wellbeing, active treatment strategies with higher dosages of quetiapine XR could be suggested in the real field. 본 연구는 기존의 항정신병 약물에서 quetiapine XR로 교체한 정신분열병 환자를 8주간 전향적으로 조사하여 임상적 이득과 주관적 안녕감의 변화를 평가한 개방형 다기관 공동 연구이다. 총 1,494명의 환자를 모집하였으며 이중 8주 연구과정을 완료하고 포함기준에 부합하고 연구계획을 위반하지 않은 1,204명의 환자를 분석한 결과, quetiapine XR 교체 후 임상적 이득과 주관적 안녕감이 유의하게 향상되는 것을 알 수 있었다. quetiapine XR을 고용량으로 시작할수록 이러한 개선 효과가 뚜렷하게 나타났는데 하루 한 번 복용뿐 아니라 증량이 손쉽도록 개발된 제형인 만큼 치료 시작 단계부터 적극적인 용량 적용이 추천된다.

만성 정신질환자 가족의 우울증상 및 관련 요인 조사

심민영,임선진,김진훈,권오향,조성진,김석주,김계현,이병학,한덕현 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.4

Objectives : It has been reported that caregivers of patients with chronic mental illness including schizophrenia are in higher risk for psychological and physical health problem. This study was performed to evaluate the depressive symptoms and associated factors in caregivers of patients with chronic mental illness. Methods : The subjects were 77 unaffected caregivers (30 parents, 30 siblings, 10 offspring, and 7 spouses) of patients with chronic mental illness (62 schizophrenia, 4 schizoaffective disorder, 11 bipolar disorder) and 100 healthy controls. Depressed mood was assessed by Beck Depression Inventory (BDI) in all subjects. For their sick family members, clinical factors including psychotic symptoms using the Positive and Negative Syndrome Scale (PANSS), duration of illness, number of admission were assessed. Results : The mean BDI score of the caregivers was significantly higher than that of control subjects (11.2±11.6 and 8.0±17.5). Given that 23.4% of family group and 23.0% of control group are attributed to mild to moderate depressed state and 22.0% of family group and 8.0% of control group to above moderate depressed state, significant depressive symptom is more frequently observed in family group. The mean BDI score of parent group was higher than that of sibling group controlling for sex and age. In the parent group, BDI scores are positively correlated with age while the offspring and spouse group had negative correlation between BDI scores and age. Higher age, lower socioeconomic state, more severe positive symptom scores of patients were potential predictors for BDI scores of caregivers. Conclusion : This study showed that caregivers of patients with chronic mental illness have significant depressive symptoms. It may be suggested that depressive symptoms of caregivers are associated with aging, low socioeconomic state, and severe positive symptom rather than chronicity of their sick family members.

Psychological trauma of Middle East Respiratory Syndrome victims and bereaved families

심민영 한국역학회 2016 Epidemiology and Health Vol.38 No.-

전해질 용액에서 용매 및 이온의 활동도 계수

심민영,김기창 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.A

In this work we measured the total pressure of the aqueous solutions and the methanol-water solutions dissolved with inorganic salts, at 25℃. In organic electrolytes used in this work were K₂SO₄and (NH₄)₂SO₄. Using the measured vapour pressures the activity coefficient of solvents and the mean ionic activity coefficient were obtained through thermodynamic relations. The activity coefficients of solvent and the mean ionic activity coefficirnt obtained in this work were fitted with Macedo's model and Acard's model. Both two models were good agreeable to the vapor pressure and the mean ionic activity coefficient for the electroyte aqueous solutions. For electrolyte /methanol/water solutions, Macedo's model had much deviation from experimental data, while Acard's model showed a good agreement with experimental data.

메스암페타민 의존자에서 우울감과 단양 기간과의 연관성

심민영,한덕현,김석주,윤수정,배수진,김형준,김다정,이지영,류인균 한국정신신체의학회 2006 정신신체의학 Vol.14 No.2

건설업 근로자의 직무스트레스가 건설공사의 하자에 미치는 영향

심민영,박해천,이경훈,조상훈 대한안전경영과학회 2009 대한안전경영과학회 학술대회논문집 Vol.2009 No.11

The global economic recession caused a great change of the labor environment such as restructurings and unstable employment. This facts brought about an increase in sense of rivalry, over workload, job uncertainty and lowering of self-confidence. Due to the fact that the work process and employing system in construction field is little differ from normal industries, especially, labors working in construction field are much exposed to the job stress. On this study, we survey construction-field labors and made an analysis of the gathered data through the statistic method to reveal what kind of job-stress factors influence on the defects of construction works. As the result, we investigated the truth of the induction factors which cause the job-stress in costruction field and proposed an alternative plan for an effective job-stress management which make the defect rate low.

메스암페타민 의존자에서 우울감과 단약 기간과의 연관성

심민영,한덕현,김석주,윤수정,배수진,김형준,김다정,이지영,류인균,Sim, Min-Young,Han, Doug-Hyun,Kim, Seog-Ju,Yoon, Su-Jung,Bae, Su-Jin,Kim, Heng-Jun,Kim, Da-Jung,Rhee, Jee-Young,Lyoo, In-Kyoon 한국정신신체의학회 2006 정신신체의학 Vol.14 No.2

연구목적 : 본 연구는 메스암페타민 의존자의 우울감 정도를 알아보고, 이들의 우울감이 메스암페타민 사용행태와 관련이 있는지 알아보기 위해 실시되었다. 방법: 메스암페타민 의존자 43명과 대조군 40명을 대상으로 메스암페타민 사용행태를 조사하였고, Beck 우울척도(Beck Depression Inventory, BDI)를 이용하여 우울감에 대해 알아보았다. 결과: 메스암페타민 군의 평균 BDI 점수는$14.1{\pm}7.7$점으로 대조군의 $7.3{\pm}5.7$점에 비해 유의하게 높았다(t=4.04, df=65, p<0.001). 의미있는 우울감을 호소하는 이의 비율도 대조군(경도-중등도 : 22.6%, 중등도-중증 : 3.2%)에 비해 메스암페타민 의존자(경도-중등도 : 38.9% : 중등도-중증 : 27.8%)에서 더욱 컸다(p=0.001). 성별, 연령, 음주량과 흡연량을 보정한 후에도 메스암페타민 의존자에서 우울감을 호소하는 이가 더 많았다. (OR=300.7, p=0.012). 메스암페타민 의존자의 BDI점수는 메스암페타민 단약기간과 유의한 음의 상관관계를 보였지만(r=-0.35, n=36, p=0.042), 메스암페타민 사용 용량이나 사용 기간과는 유의한 상관관계를 보이지 않았다(r=-0.08, n=36, p=0.677 ; r=-0.08, n=36, p=0.658). 결론: 메스암페타민 의존자는 대조군에 비해 우울감이 심하며 의미있는 우울감을 보고하는 경우도 더 흔하였다. 메스암페타민 의존자의 우울감은 메스암페타민 사용 정도와는 관련이 없었으나, 장기간의 단약을 통해 감소할 가능성이 시사되었다. Objectives : The aim of this study is to evaluate depressive symptom of methamphetamine(MA) dependent subjects and the association between depressive symptom and characteristics of methamphetamine use. Methods : Forty three MA dependent subjects and 40 healthy comparison subjects were recruited in this study. Characteristics of substance use and depressive symptom using Beck Depression Inventory (BDI) were evaluated. Results : Average BDI score of methamphetamine group is $14.1{\pm}7.7$, which is significantly higher than that of healthy comparison subjects $(7.3{\\pm}5.7)$ (t=4.04, df=65, p<0.001). Given that 38.9% of MA dependent subjects and 22.6% of healthy comparison subjects are attributed to mild to moderate depressed state and 27.8% of MA dependent subjects and 3.2% of healthy comparison subjects to moderate-severe depressed state, depressive symptom is more frequently observed in MA dependent subjects relative to healthy comparison subjects (p=0.001). On covariating as sex, age, alcohol use and smoking, prevalence of depressive symptom is still higher in MA dependent subjects than healthy comparison subjects (OR=300.7, p=0.012). BDI scores of MA dependent subjects are correlated with abstinence period (r=-0.35, n=36, p=0.042) but not with cumulative dose or duration of use (r=-0.08, n=36, p=0.677 : r=-0.08, n=36, p=0.658). Conclusion : Depressive symptom was severe and frequently observed in MA dependent subjects. This study suggested that depressive symptom of MA dependent subjects might be not associated with degree of MA use but decreased by persistent abstinence.

코로나바이러스감염증-19와 관련된 정신건강 문제

심민영 ( Minyoung Sim ) 대한내과학회 2020 대한내과학회지 Vol.95 No.6

The novel coronavirus disease 2019 (COVID-19) pandemic has spread across the world, reducing social interactions and causing substantial psychological distress and economic losses. This review summarizes the psychological effects of the COVID-19 pandemic in terms of uncertainty, the loss of autonomy associated with preventive measures, and secondary stressors such as potential future economic losses. (Korean J Med 2020;95:360-363)