http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
신영아,박혜령,홍희도,신광순,Shin, Young-A,Park, Hye-Ryung,Hong, Hee-Do,Shin, Kwang-Soon 한국식품영양학회 2012 韓國食品營養學會誌 Vol.25 No.4
In order to develop new physiologically active polysaccharides from persimmon leaves, two different crude polysaccharides were prepared using hot water (PLW-0) and pectinase digestion (PLE-0) and their immuno-stimulating activities were estimated. PLW-0 and PLE-0 showed similar sugar compositions with 15 different sugars, including rarely observed sugars in general polysaccharides such as 2-O-methyl-fucose, 2-O-methyl-xylose, apiose, aceric acid, 3-deoxy-D-manno-2-octulosonic acid, and 3-deoxy-D-lyxo-2-heptulosaric acid, but the uronic acid content of PLE-0 was lower than that of PLW-0 caused by pectinase treatment. Both PLW-0 and PLE-0 showed potent anti-complementary activity in a dose-dependent manner which was similar to a known immuno-stimulating polysaccharide, PSK, from Coriolus versicolor. The activity of PLE-0 at a low concentration ($100{\mu}g/m{\ell}$) was higher than that of PLW-0. In an in vitro cytotoxicity analysis, PLW-0 and PLE-0 (up to $1,000{\mu}g/m{\ell}$) did not affect the growth of peritoneal macrophages and Colon 26-M3.1 carcinoma cells. In contrast, they enhanced lymphocyte proliferation activity. Peritoneal macrophages stimulated with PLW-0 and PLE-0 produced various cytokines, such as IL-6 and IL-12. However, PLE-0 was more effective on the cytokine production. Intravenous administration of PLW-0 and PLE-0 significantly augmented natural killer (NK) cell cytotoxicity against Yac-1 tumor cells 3 days after the treatment of polysaccharide fractions. But NK cells obtained from the PLE-treated group showed higher tumoricidal activity even at a low dose of $40{\mu}g$/mouse. In experimental lung metastasis of Colon 26-M3.1 carcinoma cells, prophylactic administration of PLW-0 and PLE-0 significantly inhibited lung metastasis in a dose-dependent manner and PLE-0 was more effective on the inhibition of cancer metasasis. The results lead us to conclude that the pectinase-treated process is indispensable to preparing polysaccharides with higher immune-stimulating activity from persimmon leaves.
조기위암에서 림프절 전이 및 재발에 영향을 주는 위험인자 분석
신종근,신영도,윤충,주흥재,Shin Jong Keun,Shin Young Do,Yoon Choong,Joo Hoong Zae 대한위암학회 2001 대한위암학회지 Vol.1 No.2
Purpose: The prognosis of operated early gastric cancer is quite excellent and the 5-year survival rate shows to be over $90\%$. The less extensive treatment has been considered to be attractive. However, lymph node metastasis remains a main risk factor for recurrence of early gastric cancer. The author performed this study in order to determine which clinicopathologic factors of early gastric cancer influence lymph node metastasis and recurrence. Materials and Methods: A retrospective study was conducted on 222 patients with early gastric cancer who had been treated by gastrectomy combined with D2 or more extended lymph node dissection between January 1991 and December 1997 at the Department of Surgery, Kyunghee University Hospital. Results: Lymph node metastasis was observed in 26 patients ($11.7\%$), and the depth of tumor invasion and tumor size among clinicopathologic factors affected lymph node metastasis. The 5-year recurrence rate was $4.4\%$, and it was revealed that lymph node metastasis and depth of tumor invasion had a greater effect on recurrence than other clinicopathologic factors. Conclusion: The high risk factors of early gastric cancer in recurrence were submucosal tumor invasion, tumor size more than 2 cm, and lymph node metastasis. Patients of early gastric cancer with such high risk factors should undergo radical gastric resection than limited surgery. (J Korean Gastric Cancer Assoc 2001;1:119-123)
신중진(Shin Joong-Jin),신영도(Shin Young-Do) 대한건축학회 2011 대한건축학회논문집 Vol.27 No.5
Urban residence policy is in a state of metamorphosis. Development is changing to maintenance, maintenance to management, and many projects developed in Low-Rise residental areas are now being realized. Various projects undertaken by urban residence policy-makers relate to Low-Rise residental area management. While the purpose of projects which seek to maintain residental environment with residents’ participation is consensual, process, support methods and laws can mean that the reality often takes on a different form. This is especially true in the case of the “Green Parking Project”, a residence policy to resolve parking problems in Low-Rise residental areas. The Green Parking Project, which began in 2003, has recieved much positive appraisal in terms of results achieved and its potential. However, it is limited by problems connected with integrated environmental improvements in residental areas, owing to focucing too sharply on a parking (problem) settlement. This study discovered this problem by conducting case analysis, and it goes on to suggest methods of improvement that can contribute to Environmental improvement in Low-Rise residental areas.