메티마졸 복용에 의한 담즙 정체성 간염

신수빈,이재남,나민아,김도균,박성광 대한내과학회 2019 대한내과학회 추계학술대회 Vol.2019 No.1

Two Previously Unrecorded Fungal Species Isolated from Muui Island in Korea

신수빈,Hosung Jeon,Sieun Kim,Hyun-Ju Noh,Jong Won Jo,Kyunghun Min,손호경 한국균학회 2023 Mycobiology Vol.51 No.6

Fungi are cosmopolitan and they occupy diverse niches as consumers, producers, anddecomposers. They play critical roles in the environment by enabling nutrient cycling andgenerating a plethora of secondary metabolites. This study aimed to identify and characterizefungal strains isolated from diverse sources on Muui Island, Republic of Korea. In 2023, a totalof 86 fungal strains were collected and examined. Investigation of the morphological featuresand phylogenetic analyses of multiple barcode loci identified one putative novel species andtwo species previously unrecorded in the Republic of Korea: Colletotrichum sp., Colletotrichumguizhouense, and Fusarium brachygibbosum. This study provides a comprehensive descriptionof their molecular phylogenies and morphological characteristics. These findings will contributeto the existing knowledge about fungal species in the Republic of Korea and future researchon the fungal diversity on Muui Island.

Identification and Characterization of Fungal Pathogens Associated with Boxwood Diseases in the Republic of Korea

신수빈,김정은,손호경 한국식물병리학회 2022 Plant Pathology Journal Vol.38 No.4

Boxwood is a representative ornamental shrub that is widely used in landscaping horticulture. After pruning, damaged leaves or stems of boxwoods are unavoidably vulnerable to infection by various plant pathogens. Several boxwood diseases caused by fungi, such as Volutella blight and Macrophoma leaf spot, have been reported worldwide including Republic of Korea. In this study, we isolated and identified fungal pathogens of boxwood diseases that occurred in Korea and characterized their morphological and taxonomic characteristics. Boxwood samples showing blight symptoms were collected in Seoul, Republic of Korea, and the putative fungal pathogens Pseudonectria buxi, P. foliicola, and Neofusicoccum buxi were successfully identified. Investigation of the morphological features of the field isolates, including mycelial growth and conidial morphology, and phylogenetic analysis of multiple DNA barcode loci revealed that there were some morphological and genetic variations among isolates, but all of the analyzed isolates were closely related to the corresponding reference strains. We also found that P. foliicola strains were more virulent than P. buxi, and the N. buxi strains isolated in this study were weak pathogens or saprophytes. The results of our study will contribute to the development of control strategies for boxwood diseases caused by fungi and accelerate research on the complex ecology of boxwood diseases.

공립유치원 교사가 되기 위한 계속된 도전, 실패와 극복 이야기

신수빈,이대균 한국열린유아교육학회 2016 열린유아교육연구 Vol.21 No.1

본 연구는 3년 이상의 수험생활을 경험하면서도 공립유치원 교사가 되기 위한 도전을 하고 있는 수험생들이 겪고 있는 여러 측면의 어려움을 살펴보고, 실패의 원인을 분석해보고자 하였다. 또한 어려움에 대한 극복 방안을 알아봄으로써 계속된 도전을 하고 있는 수험생들에게 도움과 시사점을 주고자 하였다. 연구참여자로는 3년 이상의 긴 시간동안 임용고시를 준비하면서 응시경험과 수험생활을 경험한 현직교사 혹은 예비교사(수험생) 10명을 선정하였다. 연구방법으로는 개별 심층면담, 전화면담 및 e-mail 서신, 연구자의 저널을 활용하였다. 연구결과, 장수생의 어려움으로는 심리적인 어려움, 경제적인 어려움, 인간관계에서 오는 어려움, 건강상의 문제에서 오는 어려움이 있었고, 실패의 원인으로는 당일의 컨디션, 목표의식 및 의욕의 저하, 비효율적인 학습방법이 있었다. 이러한 어려움을 극복하기 위해서는 불안을 최소화하고 긍정적인 인간관계 맺기, 지속적인 건강관리 하기, 목표의식 갖기, 학습태도 변화하기 등의 방안이 나타났다. This study aimed at finding out diverse difficulties and overcoming which kindergarten teacher had tried over third time for selecting examination have experienced, and researching for the reason of failure, giving them the help. The participants of this study are 10 persons who had tried over third time for selecting examination. Individual interviews were used as a research method. Interviewees experienced psychological, economic, social, and health-related difficulties. The reasons for failure are condition of exam-day, low of willingness, and ineffective learning method, The reasons for taking the exam are stability of teaching job, difficulties of recruiting, and high possibility of passing, and hope of success.

Histomorphometric analysis of microcrack healing after the installation of mini-implants

신수빈,박판수,백승학,양일형 대한치주과학회 2015 Journal of Periodontal & Implant Science Vol.45 No.2

Purpose: The goal of this study was to investigate the histomorphometric characteristics of the healing process of microcracks in the cortical bone after the installation of mini-im¬plants (MIs). Methods: Self-drilling MIs were inserted into the tibial diaphysis of twelve adult male New Zealand rabbits. Four MIs per rabbit were placed randomly. The animals were divided into four groups according to the length of the healing period: group A was sacrificed immedi¬ately, group B was sacrificed after one week, group C was sacrificed after two weeks, and group D was sacrificed after four weeks. Cortical bone thickness was measured using mi¬cro-computed tomography, and histomorphometric analyses of the cumulative length of the microcracks (CLCr) and the total number of microcracks (NCr) were performed using hematoxylin and eosin staining. Results: The microcracks were radially and concentrically aligned in the peri-MI bone. The CLCr decreased significantly one week after the surgery, mainly due to healing of the con¬centrically aligned microcracks. The CLCr showed another significant decrease from two weeks after the surgery to four weeks after the surgery, mainly reflecting healing of the ra¬dially aligned microcracks. A statistically significant decrease in the NCr occurred as the microcracks healed from zero weeks to two weeks. However, no significant difference in the NCr was found between groups C and D. Conclusions: In order to improve the primary stability of MIs, delayed loading and a heal¬ing period of a certain length are recommended to ensure the optimal healing of micro¬cracks and bone remodeling.

Protective Effects of Traditional Korean Medicine Preparations, Herbs, and Active Compounds on the Blood–brain Barrier in Ischemic Stroke Model

신수빈,장석주,이나경,최병태,신화경 한국생명과학회 2022 생명과학회지 Vol.32 No.7

Stroke is among the leading causes of death and long-term physical and cognitive disabilities worldwide, affecting an estimated 15 million people annually. The pathophysiological process of stroke is complicated by multiple and coordinated events. The breakdown of the blood–brain barrier (BBB) in people with stroke can significantly contribute to the development of ischemic brain injury. Therefore, BBB disruption is recognized as a hallmark of stroke; thus, it is important to develop novel therapeutic strategies that can protect against BBB dysfunction in ischemic stroke. Traditional medicines are composed of natural products, which represent a promising source of new ingredients for the development of conventional medicines. Indeed, several studies have shown the effectiveness of Korean medicine on stroke, highlighting the value of Korean medicinal treatment for ischemic stroke. This review summarizes the current information and underlying mechanisms regarding the ameliorating effects of the formula, decoction, herbs, and active components of traditional Korean medicine on cerebral ischemia-induced BBB disruption. These traditional medicines were shown to have protective effects on the BBB in many cellular and animal ischemia models of stroke, and experiments in various animal species, such as mice and rats. In addition, they showed brain-protective effects by protecting the BBB through the regulation of tight junction proteins and matrix metalloproteinase-9, reducing edema, neuroinflammation, and neuronal cell death. We hope that this review will help promote further investigation into the neuroprotective effects of traditional Korean medicines and stimulate the performance of clinical trials on Korean herbal medicine–derived drugs in patients with stroke.

High-throughput emissive glass microcomponents synthesis via contact flow lithography

신수빈,이지석,전인규 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.0

We report a high-throughput synthesis of emissive microcomponents with rare-earth-doped upconverting nanocrystals (UCNs) using a contact flow lithography. Upconverting nanocrystals were synthesized using hydrothermal reaction and used as anti-Stokes emitters that absorb near-infrared (NIR) light and emit in visible spectrum. We utilized contact flow lithography for massive production of nonspherical composite microcomponents. Emissive composite microcomponents with a variety of shapes was synthesized and corresponding glass microcomponents were obtained through polymer burn-off and sintering of the composites. The synthesized particles with UCNs are stable at high temperature and have great potential to use as anti-counterfeiting platform.

중등 과학 교과 실험에서의 피지컬 컴퓨팅 기반 STEM 교육 적용

신수빈 ( Su Bin Shin ),김동현 ( Dong Hyun Kim ),김재민 ( Jae Min Kim ),김태현 ( Tae Hyeon Kim ),장명호 ( Myungho Jang ),김희주 ( Heeju Kim ),명노영 ( Rohyoung Myung ),유헌창 ( Heonchang Yu ) 한국컴퓨터교육학회 2016 한국컴퓨터교육학회 학술발표대회논문집 Vol.20 No.1

현대 사회에서 IT 기술이 급격히 발달하여 다양한 분야에 활용되고 있으며 그 중에 가장 각광받는 기술중 하나가 피지컬 컴퓨팅이다. 피지컬 컴퓨팅은 아날로그와 디지털 간의 입출력을 사용하여 비교적 일처리가 간단하며 다양한 플랫폼이 있어 접근성이 높아 피지컬 컴퓨팅을 활용한 교육 방안이 주목받고 있다. STEAM의 경우 여러 분야의 지식을 융합하여 복합적인 문제를 해결할 수 있는 방안을 제시하기 때문에 교육에 활용되고 있다. 본 연구에서는 피지컬 컴퓨팅 기반의 STEAM을 ``기온에 따른 식물의 광합성량`` 실험설계에 적용하여 실험의 편리성과 접근성을 향상시켰고 이를 통해 교육에서의 구체적인 활용 방안을 제시하고자 한다.

FiniteBlocklength 구조에서 Rate-Splitting Multiple Access의 유효성

신수빈(Shin Su Bin),박정훈(Park Jeong Hun) 한국통신학회 2023 한국통신학회 학술대회논문집 Vol.2023 No.2

사용자 중심 감정 언어 기반 배색 추천 웹 서비스 설계

신수빈(Subin, Shin),박수진(Su Jin, Park),김태희(Taihee, Kim),안현주(Hyunjoo, Ahn),정아영(Ahyoung, Jeong),유건희(Geonhui, Ryu),김태희(Taehee, Kim),정종복(Jong Bog, Joung),이상원(Lee, Sangwon) 한국HCI학회 2024 한국HCI학회 학술대회 Vol.2024 No.1

색채는 제품의 선호도에 영향을 미치는 중요한 요인으로서, 목적에 부합되는 색채를 찾는 것은 디자인과 마케팅 과정에서 중요한 문제이다. 색채 감성에 대한 다양한 연구가 진행되고, 미 기업을 중심으로 온라인 크라우드 소싱 기반 솔루션 또는 데이터 기반 조화 배색 제안 서비스 등을 제공하고 있으나 문화권, 세대별, 제품적, 시대적 요인 등을 포괄적으로 반영한 서비스는 제공되고 있지 않다. 본 연구에서는 감정 언어를 기반으로 배색을 추천해주는 웹페이지 UI/UX 를 설계하고 구현하였으며,디자인 분야 전문가 평가를 통해 본 연구에서 제안한 웹 서비스가 디자인 작업의 고도화에 도움을 줄 수 있음을 확인하였다. 인터뷰 결과에 따르면 대부분의 전문가들은 제안된 웹사이트를 직관적이고 만족스럽게 사용하였다. 시각적으로 매력적이고 간결한 디자인을 높게 평가하였으며, 10 명 중 9 명이 추후에도 이 웹사이트를 사용하거나 주변 디자인 종사자들에게 추천할 의향이 있다고 응답했다. 최종적으로, 연구에서 제안된 웹사이트는 근거 기반 배색 조합을 제공하여 기업의 비전과 가치를 명확히 표현하고 장기적인 경쟁력을 확보하는 데 도움이 될 것으로 기대된다.