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본태성고혈압 환자에서 저염식 및 교감신경차단제 사용시 요중 Catecholamines 함량 변동
장중현(Jung Hyun Chang),조영호(Young Ho Cho),이경미(Kyung Me Lee),신길자(Gil Ja Shin),이우형(Woo Hyung Lee),안영수(Young Soo Ahn),김동구(Dong Goo Kim),김경환(Kyung Hwan Kim),홍사석(Sa Suk Hong) 대한내과학회 1988 대한내과학회지 Vol.34 No.4
N/A Sympathetic activity is related to the pathogenetic mechanism in essential hypertension. It is now evident that plasma norepinephrine reflects sympathetic activity. However, there are some conflicting results concerning the levels of urine catecholamines and their significance. This study was performed to evaluate the significance of urine catecholamines as an index of sympathetic activity in essential hypertension. The study was done on thirteen patients of established hypertension. Normotensive controls were fourteen healthy individuals. The concentrations of urine norepinephrine and dopamine were detected by employing liquid chromatography-electrochemica1 detector. The results were summarized as follows: 1) Age, body surface area, G.F.R., 24 hours urine excretion of sodium and plasma renin activity were not different between normotensive and hypertensive groups. 2) There was a significant decrease in systolic and diastolic blood pressure after treatment with low salt diet and atenolol. 3) In hypertensive group, the values of urine norepine-phrine and dopamine were significantly higher than normotensive group and both were significantly reduced after treatment with low salt diet and atenolol. 4) In hypertensive group, significant correlation was observed between urine norepinephrine and dopamine levels. Also, significant correlation was observed between the decrements in systolic blood pressure and the changes in urine norepinephrine by the treatment. In conclusion, urine catecholamines, norepinephrine and dopamine, were elevated in essential hypertension, and were significantly reduced after low salt diet and atenolol therapy, and it is suggested that urine catecholamines can be useful index in evaluating sympathetic activity in essential hypertension.
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김용숙(Yong-Sook Kim),신길현(Gil-Hyun Shin) 한국산학기술학회 2016 한국산학기술학회논문지 Vol.17 No.9
본 연구는 2006년부터 2016년 3월까지 최근 10년간 「한국산학기술학회지」 논문에 게재된 교육분야 연구관련 논문 분석을 통하여 연구동향을 파악하고, 향후 연구과제에 필요한 기초자료를 제공함으로써 균형 있는 연구를 위한 방향과 학술방향을 제시하는데 목적이 있다. 분석대상이 된 교육학 관련 논문 143편을 분석기준 따라 연도별 논문 수, 연구자 전공별, 저자수별, 연구대상별, 연구주제별, 연구방법별(연구유형, 자료분석)로 분석하였다. 그 결과 연도별 논문 수는 2015년이 31편으로 가장 많이 발표된 것으로 나타났다. 연구자 전공별은 유아교육전공 77명, 교육학전공 64명 순으로 나타난 반면, 상대적으로 그 외 교과목 전공 관련 연구는 매우 낮은 것으로 나타났다. 또한 저자수별로는 2인 51편, 단독이 44편 순이였는데, 4명 이상의 공동연구는 총 10편으로 적은 것으로 나타났다. 연구대상별로는 유아가 28편, 유아교사가 24편순으로 나타났다. 연구주제는 철학․역사․심리․사회가 35편, 교사교육이 27편순이었고, 유아교육분야에서는 교사교육, 발달심리․부모 순으로 나타났다. 연구방법은 양적연구 중 상관연구가 47편이, 자료분석방법은 차이검증 중 t-검증이 가장 많은 것으로 분석되었다. 본 연구동향 분석을 계기로 한국산학기술학회가 향후 연구논문의 고른 게재를 통하여 우리나라 학계의 균형 있는 발전에 기여하기를 기대한다. This study attempts to understand the trend of research in the field of education contributed theses of the 「Korea Academia-Industrial Society」in the 10 year period from 2006 to March, 2016, and provide the basic data needed for further research projects. It provides the direction for balanced academic research. The 143 theses contributed over this 10 year period were analyzed to determine the number of thesis per year, major of the researchers, number of co-authors, object of research, subject of research, and research method. It was found that the greatest number of theses were published in 2015. There were 77 researchers who majored in early childhood education and more than 64 researchers who majored in Education, while few researchers majored in other fields of study. The number of papers published by two co-authors was 51, that by one author was 44, and that by more than four researchers was 10. The numbers of papers whose object of research was infant and teacher education were 28 and 24, respectively. The number of papers whose subject of research was philosophy, history, psychology, or social science was 35, and that involving education was 27. There were 47 papers whose method of research was quantitative research. The most prevalent method of data analysis was difference verification. Through this analysis of the research trends, we expect to contribute to the balanced development of the academic world in Korea.
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염색체 이상과 일과성 완전방실해리의 소견을 보인 원발성 Aldosteronism~1 예 보고
허준,이우형,장중현,김혜옥,신길자,박이갑 대한내과학회 1986 대한내과학회지 Vol.31 No.6
In 1955, Jerome Conn first described a syndrome of hypertension, hypokalemia and hyperaldo-steronism with otherwise normal adrenal function. He named this entity $quot;Primary Aldosteronism$quot;. Thirteen cases of primary aldosteronism have been reported in Korea. We recently experienced a case of primary aldosteronism associated with high degree AV block. This 24-year-old female patient visited our hospital because of fever, back pain and paresthesia. As the diagnostic procedures, several hormonal assays, C.T. of adrenal gland and cytogenetic study were employed. She has been accompanied with a chromosomal anomaly: chromosome 18 mosaicism(46, XX/45, XX,-18), detected by karyotyping undertaken because of the patient's symptoms of amenorrhea, absence of pubic hair and breast development. This is thus a report in a case of primary aldosteronism in a patient with autosomal anomaly, presented along with the brief review of literature.
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