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신경철 ( Kyeong Cheol Shin ) 대한결핵 및 호흡기학회 2011 Tuberculosis and Respiratory Diseases Vol.71 No.1
Many findings suggest that chronic obstructive pulmonary disease (COPD) imposes an enormous burden on pa-tients, health-care professionals and society. COPD contributes to morbidity and mortality and to a significant use of health-care resources. In spite of a higher prevalence of COPD in Korea, the result of COPD treatment is not effective. The purpose of this article was to review recent advances in the study of COPD in Korea with the aim of improving effective management. This review highlights articles pertaining to the following topics; prevalence, assessment of COPD, risk factors for hospitalization, co-morbid diseases, phenotypes, and treatment issues.
( Hyun Hye Chu ),신경철(공동저자1) ( Kyeong Cheol Shin ),이경수(교신저자) ( Kyeong Soo Lee ) 대한임상병리사협회 2014 임상생리검사학회 발표자료집 Vol.2014 No.-
배경(Background): This study was conducted to analyze association between airway hyperresponsiveness and clinical asthma symptoms in patients using survey with targets of patients who underwent medical treatment for cough in the primary care clinic but visited the general hospital because the symptoms were not improved. The purpose of this study was to analyze the association between result of clinical examination for airway hyperresponsiveness which was gold standard and questionnaires about asthma symptoms and determine the availability in the diagnosis of asthma. Thus, this is to help the technician to check progress. 방법(Methods): Examination for airway hyperresponsiveness and clinical test were performed with targets of 311 patients who were between 18 years old and 70 years old and visited a university hospital located in Daegu metropolitancity from March 2011 to June 2012 because of chronic cough. 결과 (Results): There were significant associations between airway hyperresponsiveness and family medical history. There was no significant association between clinical symptom and survey for cough, but there was significant association with wheezing. There were significant associations with sleeping difficulty, difficulty in breathing at dawn, atopy symptoms and nasal symptoms. According to the results of non parametric statistics, it was found that the proportion of positive group for airway hyperresponsiveniss was higher with more numbers of significant symptoms used in this study. 결론(Conclusion): It is considered to be helpful to find potential asthma patients using useful related symptom questionnaires which were used in this study. It is possible to be used as basic information to develop the questionnaires to identify hypersensitivity of airway. It is also considered to be a great help to process of examinations. It is also considered to be a great help to process of examinations.
늑막삼출환자에서 늑막액 Cholesterol 농도와 늑막액 / 혈청 Cholesterol 비의 진단적 의의
김성숙(Seong Suk Kim),신경철(Kyeong Cheol Shin),최희진(Hee Jin Choi),류헌모(Hon Mo Ryu),서정일(Jeong Ill Suh),임종식(Jong Sik Lim),이재성(Jae Seong Lee),정진홍(Jin Hong Chung),이관호(Kwan Ho Lee),이현우(Hyun Woo Lee) 대한내과학회 1994 대한내과학회지 Vol.46 No.3
N/A Objectives: To validate the use of pleural cholesterol and the pleural cholesterol/serum cholesterol ratio (P-/S-CHOL) for differentiating between transudates and exudates in pleural effusion of diverse etiology and to compare the diagnostic efficacy of these parameters with those of Light criteria. Methods: Between September 1991 and June 1992, 118 patients with pleural effusion were studied. We measured pleural protein/serum protein ratio, pleural LDH, pleural LDH/serum LDH ratio, pleural cholesterol and pleural cholesterol/serum cholesterol ratio. Mean values of the parameters in transudates group and exudates group were compared, and the misclassification rate and the diagnostic efficacy for each parameters were calculated. Results: 1) The pleural cholesterol (P-CHOL) values were 21.88±8.86rng/dl for transudates, 86.38±30.09mg/dl for tuberculous exudates, 76.96±18.63 mg/dl for neoplastic exudates, and 85±24.69mg/dl for the parapneumonic effusion group (p<0.001 in tuberculous and neoplastic exudates, p<0.05 in parapneumonic effusion group). And the pleural cholesterol/serum cholesterol ratio (P-/S-CHOL) were 0.17±0.07 for transudates, 0.64±0.16 for tuberculous exudates, 0.52±0.16 for neoplastic exudates, and 0.68±0.17 for the parapneumonic effusion group (p<0.001). 2) Misclassification rates for each parameters in seperating the exudate group from the transudate group were as follows; pleural protein/serum protein ratio (P-/S-PROT) 1 69%, P-/S CHOL 2.54%, P-CHOL 3.38%, pleural LDH (P-LDH) 4.23%, pleura LDH/serum LDH ratio (P-/S-LDH) 4.23%. 3) With a cut-off value of 50mg/dl, P-CHOL had a sensitivity of 96% and a specificity of 10096 for diagnosis of exudates, and with a cut-off value of 0.3, P-/S-CHOL had a sensitivity of 98% and a specificity of 94%. 4) Diagnostic efficiencies for each parameters in seperating the exudate group from transudate group were as follow; P-/S-PROT 98%, P-/S-CHOL 97%, P-CHOL 96%, P-LDH 95%, and P-/S-LDH 95%. 5) In the exudate group, pleural cholesterol was significantly correlated with serum cholesterol (r=0.5S84, p<0.001) and the pleural LDL/Cholesterol ratio was significantly correlated with the serum LDL/Cholesterol ratio (r=0.4408, p<0.001). Conclusion: we think that measurements of P-CHOL and P-/S-CHOL is of great value for distinguishing between pleural exudates and transudates, and high P-CHOL and P-/S-CHOL values appear to be related to increased permeability of pleural capillaries. Therefore, we suggest that determination of these parameters should be included in routine laboratory analysis of pleural effusions.