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송춘익(Choon Eck Song),심규식(Kyu Sik Shim),구완서(Wan Suk Koo),박동준(dong JUne Park),김철민(chul Min Kim),하현권(Hyun Kwon Ha),허미경(Mi Kyung Hur),강문원(Moon Won Kang) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.2
This is a report of two cases of adenocarcinoma in ileum of the small intestine. Ileal adenocar- cinoma has been noted at its rarity, etiology, distribution, and poor prognosis. Recently we experi- enced two interesting cases. One dveloped in 25 year-old rnan, and the other in 42 year old man, vho had treated by segmental resection and chemotherapy, was followed by development of gastric carcinoma after 8 year-survival.
Raynaud 현상을 동반한 교원성질환에 대한 임상적 고찰
김우중(Woo Joong Kim),송춘익(Choon Ik Song),현영(Young Hyun),김호연(Ho Youn Kim),이경식(Kyung Sik Lee),김동집(Dong Jip Kim) 대한내과학회 1986 대한내과학회지 Vol.31 No.1
N/A Raynaud`s phenomenon is a disorder characterized by digital vasospasm, with sequential phases of digital pallor, cyanosis and erythema generally precipitated by exposure to cold or emotional stimuli. It is well known that Raynaud phenomenon is a frequent, early, premonitory symptom often associated with scleroderma. So we studied 26 cases of connective tissue diseases associated with Raynaud phenomenon to define the features of patients with Raynaud phenomenon that predict the evolution of connective tissue diseases especially scleroderma, The results were as follows: 1) The male/female incidence was 1 and 25 cases respectively, with the mean age of 34.2 years. 2) In 26 cases, systemic lupus erythematosus were 16 cases(56.5%), progressive systemic sclerosis were 8 cases(34.7%) and rheumatoid arthritis and cutaneous vasculitis were 1 cases respectively. 3) Fluorescent antinuclear antibody(FANA) revealed 8 cases(30.8%) of homogenous pattern, 8 cases(30.8) of speckled pattern, 1 case(3.8%) of nucleolar pattern and 4 cases(15.4%) of negative results. 4) The common symptoms and signs of systemic lupus erythematosus associated with Raynaud's phenomenon were renal involvement, CNS involvement, A-V conduction defect, pulmonary infiltration, serositis and liver function abnormalities. It was noticeable that Raynaud phenomenon was a major or initial manifestation in 3 cases(19.8%) of systemic lupus erythematosus. 5) The clinical manifestation of scleroderma were cutaneous manifestation, pulmonary infiltration, esophageal dysfunction, dryness of mouth, bone tuft resorption, proteinuria and calcinosis. 6) The average duration of Raynaud's phenomenon before evolving into clinical scleroderma was 4.3 years. 7) FANA pattern of scleroderma revealed speckled pattern(57%), hemogenous(14%), nucleolar (14%) and negative result(14%). 8) Hypergammaglobulinemia(33%), rheumatoid factor(38%), cryoglobulinemia(13%) were also found in scleroderma. 9) Skin biopsy of scleroderma revealed 2 cases of mild perivascuar mononuclear cell infiltration and 1 case of increased collagen bundle associated with flattening of epidermis under light microscopic examination. Immunofluorescent examination revealed 1 case of linear deposit of IgM along the- dermal-epidermal junction and 1 case of diffuse- nuclear deposit in epidermis.
차상복(Sang Bok Cha),송춘익(Choon Eck Song),양철우(Chul Woo Yang),최규용(Kyu Young Choi),성기열(Ki Yul Sung),이안희(Ah Hee Lee),박승만(Seung Man Park) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.2
61 year-old man with malnutrition and ascite was diagnosed to have Menetrier's disease by gastrofiberscopy and UGIS. Work-up showed classic menetriers disease with enlarged gastric rugae and hypoalbuminemia due to protein-losing gastropathy. 50 days after medical conservative treatement, total gastrectomy was performed in order to improve hypoalbuminemia. Microscopically there was a increased number of mucous cell involving the parietal and chief cell. We consider it mixed mucous-glandular cell type hyperplasia by Mings classification. The pathogenesis and pathophysiology of the disease are poorly understood. Indeed, there is sti]1 controversy regarding its classification, cause and management. A brief review of classification, etiology, pathophysiology, classical pictures and management of Menetriers disease is presented.
홍대식,유경진,이현재,이용관,송춘익,정희영,강문원,신완식 대한감염학회 1985 감염 Vol.17 No.2
The new cephamycin-type antibiotic, cefotetan is very stable to β-lactamase, it possesses a good antibacterial activity on aerobic and anaerobic gram-negative cocci and bacilli. Clinical values of cefotetan were evaluated in 26 patients with a clinical diagnosis of bacterial infection of the urinary, respiratory and gastrointestinal tract. The drug was administered intravenously in dose of 1∼4g per day for 1 to 16 days. The clinical response was satisfactory in 11(100%) patients with urinary tract infections, 8(61.5%) of 13 patients with respiratory tract infections, 2(100%) patients with gastrointestinal tract infections. Overall, cefotetan was effective in 21(80.8%) of all patients treated. During the treatment 5 patients showed adverse effects including nausea, diarrhea, skin rash, drug fever. And elevation of hepatic enzyme levels occured in 1 of all patients treated. But the majority of adverse effects disappeared within 2∼3 days.