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아스피린이 흰쥐 뇌의 c-Fos 면역반응성에 미치는 영향
손창목(Chang-Mok Son),김철홍(Chul-Hong Kim),유기수(Ki-Soo Yoo) 대한체질인류학회 2001 대한체질인류학회지 Vol.14 No.1
간추림: 아스피린을 미리 경구 투여한 후 포르말린으로 체성동통을 유발시켜 동통에 대한 아스피린의 효과를 뇌의 신경세포의 c-Fos 면역반응성 변화로 밝히고자 하였다. 체성동통을 유발시킨 후 일정한 기간이 경과한 뒤 뇌를 적출하여 뇌절편을 만들어 c-Fos 단백의 출현을 관창한 결과 뇌의 띠피질, 일차체성감각영역 벚 해마 부 위에서 C-Fos 번역양성반응을 일으킨 신경세포의 수가 증가하였고, 아스피린을 투여한 군이나 투여하지 않은 군 모두에서 전시기에 걸쳐 포르말린을 주사하지 않은 군보다 c-Fos 면역양성반응세포수가 현저히 않았으며, 동통유발 2시간 후 최고치에 도달하였으며, 아스피린을 투여한 군의 c-Fos 연역양성반응세포수는 아스피린을 투여하지 않은 굽보다 전시기에 걸쳐 적었다는 연구 결과를 얻었다.
정민호(Min Ho Jeong),강병완(Byeong Wan Kang),손창목(Chang Mok Son),김혜숙(Hye Sook Kim) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.73 No.2
Neuroendocrine tumor (NET) of the colon and rectum has been reported to have a low incidence and aggressive progression; it is frequently misdiagnosed and its treatment is not well documented. Four NET cases were collected at our hospital during the previous year of a colon cancer survey. Endoscopic mucosal biopsy of the colon was done for each case and all the cases proved to be adenocarcinomas. Curative surgery was conducted after the preoperative diagnostic and staging evaluation was completed. The locations of the primary lesions of the patients were all different; cecum, ascending colon, splenic flexure colon and sigmoid colon. The disease was advanced in all cases and the first postoperative diagnosis was poorly differentiated adenocarcinoma. Immunohistochemical tests followed and all the cases were positive for chromogranin A staining. A retrospective study was then conducted.
한광수 ( Kwang Soo Han ),이정헌 ( Jung Hun Lee ),손창목 ( Chang Mok Son ),배국환 ( Koock Howan Bae ),박정실 ( Jung sil Park ),배종인 ( Jong In Bae ),주재영 ( Jae Young Ju ) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.7
Intestinal obstruction is a rare but important complication of pregnancy and puerperium leading to increased maternal and fetal motality. Diagnosis is often delayed or missed because many of the manifestations of intestinal obstruction such as nausea, vomiting and abdominal pain can be interpreted as pregnancy related symptoms. This delay in diagnosis or misdiagnosis, reluctance to surgery during pregnancy are thought to be responsible for the high maternal and fetal death rate. So we report a case of postpartum small bowel obstruction following vaginal delivery with a review of the literature.
김범희 ( Beom Hee Kim ),박희욱 ( Hee Ug Park ),박승근 ( Seung Keun Park ),전승민 ( Soung-min Jeon ),정찬우 ( Chan Woo Jung ),손창목 ( Chang Mok Son ),최현욱 ( Hyun Wook Choi ),김혜숙 ( Hye Sook Kim ) 대한소화기학회 2018 대한소화기학회지 Vol.72 No.1
Human anisakiasis is a disease caused by an infestation of the third stage larvae of family anisakidae. The ingested larvae invade the gastrointestinal wall, causing clinical symptoms that include abdomen pain, nausea, and vomiting. Although enteric anisakiasis is extremely rare, it can induce intestinal obstruction. We report a case in which emergency surgery was needed due to intestinal obstruction that coincided with symptoms related to anisakiasis, along with a brief literature review. (Korean J Gastroenterol 2018;72:33-36)
대장내시경 및 CT 검사에서 종양으로 오진도니 맹장 게실염 1예
김경원,최정호,김은영,김혜숙,정규영,박승근,김강희,옥종한,구영훈,박희욱,손창목 대한소화기내시경학회 2000 Clinical Endoscopy Vol.21 No.1
Cecal diverticulitis is a rare entity and remains a difficult diagnostic problem. Most patients are presented with an acute pain in the abdomen, which is nearly indistinguishable from that of appendicitis. Preoperative diagnostic studies are not helpful. Even with an operation, the correct diagnosis may be difficult to predict with certainty. The differential diagnosis between a cecal malignant tumor and a mass caused by inflammation due to cecal diverticulitis is difficult. Suspicion of a neoplastic process continues to prompt colectomy in an emergency setting. If diagnosed preoperatively, it can be treated effectively with a broad spectruum of antibiotics without surgical intervention. The physician must be aware this condition and be prepared to choose the most apropriate treatmetn. A case was experienced involving of solitary cecal diverticulitis misdiagnosed as a cecal tumor in a 61-year-old female. This unique form of diverticulitis is herein reported with literature review.