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차종환(Cha, Jong-Hwan),한상열(Han, Sang-Yeol),이호준(Lee, Ho-Jun),고장욱(Go, Jang-Uk),이현주(Lee, Hyeon-Ju),오시덕(O, Si-Deok),신형기(Sin, Hyeong-Gi),이수갑(Lee, Su-Gap),김태욱(Kim, Tae-Uk),성대영(Seong, Dae-Yeong),박성배(Park, Seong 한국신재생에너지학회 2005 한국신재생에너지학회 학술대회논문집 Vol.2005 No.11
본 연구에서는 에너지 및 환경에 대한 문제가 대두되면서 기술 개발의 필요성이 높아지고 있는 풍력발전시스템에 대하여 750kW급 Geared Type 가변속 풍력 발전시스템을 개발하였다. 풍력발전시스템이 급속히 대용량화됨을 고려하여 MW급의 기술 조합이 반영되도록 설계하였으며, 베어링과 같은 국내 인프라가 부족한 구성품을 제외한 모든 구성기기들을 자체 설계/제작하였다. 블레이드는 국내 풍황에 적합하도록 자체 에어포일을 설계하여 개발하였으며, 가변속 제어를 위한 이중 여자 유도발전기 및 제어기와 Down sizing 구현을 위한 유성 및 헬리컬 기어 혼합형 증속기를 개발하여 시동 풍속 3.5m/s, 정지 풍속 25m/s, 정격 풍속은 12.7m/s이며 IEC 61400-1의 Class I 에 준한 750kW급 풍력 발전시스템을 개발하였다.
복분자 열매(Rubus coreanus Miquel)의 항산화 활성 및 생리활성물질
진동혁(Dong-Hyeok Jin),성종환(Jong-Hwan Seong),이영근(Young-Geun Lee),김동섭(Dong-Seob Kim),정헌식(Hun-Sik Chung),김한수(Han-Soo Kim) 한국유화학회 2016 한국응용과학기술학회지 Vol.33 No.3
The black raspberry (Rubus coreanus Miquel) contains anthocyanin, tannins, gallotannin, gallic acid, ferulic acid and phenolics. It brightens the eyes and protects the liver and kidneys. It was effective for anti-aging. Thus, the purpose of this study was to inform the excellence of black raspberry and to screen antioxidant activity to ensure the possibility as a functional material. In this study, bioactive compounds in black raspberry were determined. Additionally, black raspberry was extracted by CM (chloroform:methanol, 2:1, v/v), 70% methanol and 70% ethanol, and were investigated and compared in vitro methods. Total phenol and flavonoid contents were measured to compare each different solvents. In addition, DPPH radical scavenging activity and ABTS radical scavenging activity, ferric reducing antioxidant power, reducing power were determined to measure the antioxidant activity. The results were the highest in 70% ethanol extracts, and the higher the concentration showed a significantly higher antioxidant capacity. When observed the relationship between the study, antioxidant activity of black raspberry was supposed to affect by the anthocyanin, phenol and flavonoid contents.
실크 세리신이 이상지질혈증 흰쥐의 지질대사 개선작용에 미치는 영향
김한수(Han -Soo Kim),성종환(Jong-Hwan Seong),이영근(Young-Guen Lee),윤호동(Ho-Dong Yoon),강진순(Jin-Soon Kang),Cheng-Liang Xie,신지문(Ji-Moon Shin) 한국생명과학회 2010 생명과학회지 Vol.20 No.10
이상지질혈증 흰쥐에 있어서, 누에로부터 효소 처리하여 추출한 세리신의 섭취가 혈청 지질대사 개선효과 및 지질대사 이상 등에 관여하는 지질성분 및 효소의 활성 변동을 검토하기 위하여 이상지질혈증 Sprague Dawley계 흰쥐 수컷을 사용하여 본 실험을 행하였다. 기본식이만을 섭취한 대조군인 BW군을 비롯한 이상지질혈증 유발군(HCW군), 이상지질혈증 유도에 세리신을 급여시킨 군(HCS군)을 5주간 실험 사육하였다. 혈청 총 콜레스테롤, 동맥경화지수, LDL-콜레스테롤, 중성지방, 인지질, 유리 콜레스테롤 농도, 콜레스테롤 에스테르 비 및 혈당 농도 등은 실크 세리신을 급여시킨 군(HCS군)에서 농도가 감소되는 것으로 나타났다. 한편, HDL-콜레스테롤 및 총 콜레스테롤에 대한 HDL-콜레스테롤 비 등은 세리신 섭취(HCS군)에 의해서 증가되는 것으로 나타났다. 혈청 중 alkaline phosphatase (ALP) 및 aminotransferase (AST & ALT)의 활성은 이상지질혈증을 유도 시킨 후 실크 세리신을 섭취시킴으로써 효소 활성이 억제되는 것으로 나타났다. 이상과 같은 결과에서, 실크 세리신이 흰쥐의 혈청 지질대사 이상 등에서 오는 이상지질혈증의 예방 및 개선에 효과가 있을 것으로 생각된다. The principal objective of this study was to investigate the effects of silkworm sericin extract supplementation on the improvement of lipid compositions, blood glucose levels and enzyme activities in the serum of dyslipidemic rats. The rats were fed the experimental diet for 5 weeks. Concentrations of total cholesterol, atherosclerotic index, LDL-cholesterol, triglyceride (TG), phospholipid (PL), free cholesterol, cholesteryl ester ratio and blood glucose in serum were higher in the dyslipidemic group (group HCW) and cholesterol-plus-silkworm sericin extract intake group (group HCS) than those in the control group (group BW, basal diet-plus-water). However, the concentrations of total cholesterol, atherosclerotic index, LDL-cholesterol, TG, PL, free cholesterol, cholesteryl ester ratio and blood glucose level in serum were lower in group HCS than those in group HCW. On the other hand, the HDL-cholesterol level and the ratio of HDL-cholesterol to total cholesterol in group HCS were higher than in group HCW. The activities of alkaline phosphatase (ALP) and aminotransferase (AST & ALT) in serum were lower in group HCS than in the dyslipidemic group HCW. From the above results, it was suggested that silkworm sericin extract intake was effective in the prevention and improvement of lipid components, blood glucose level and enzyme activities in the sera of dyslipidemic rats.
키토산 올리고당이 당뇨성 흰쥐의 혈당과 혈중 지질성분 및 효소활성에 미치는 영향
김한수 ( Han Soo Kim ),성종환 ( Jong Hwan Seong ) 한국식품영양학회 2008 韓國食品營養學會誌 Vol.21 No.3
The principal objective of this study was to assess the effects of chitosan oligosaccharide supplementation on the improvement of blood glucose, lipid components and enzyme activities in the serum of streptozotocin(STZ, 55 mg/kg B.W., I.P. injection)-induced hyperglycemic rats fed on experimental diets for 5 weeks. The concentrations of blood glucose, total cholesterol, atherosclerotic index, LDL, LDL-cholesterol, free cholesterol, cholesteryl ester ratio, triglycerides(TG) and phospholipids(PL) in serum were remarkably higher in the hyperglycemic group(group BSW) and STZ(I.P.)+chitosan oligosaccharide supplementation group(group ECW) than those in the control group(group BW, basal diet+water). However the concentrations of blood glucose, total cholesterol, atherosclerotic index, LDL, LDL-cholesterol, free cholesterol, cholesteryl ester ratio, TG and PL in serum were lower in the ECW group than in the BSW group, whereas the ratio of HDL-cholesterol concentration to total cholesterol and HDL-cholesterol concentration in the ECW group were higher than in the BSW group. The activities of alkaline phosphatase(ALP) and aminotransferase(AST, ALT) in serum were lower in the ECW group than in the hyperglycemic BSW group. The results shown above suggested that chitosan oligosaccharide supplementation effectively improves blood glucose, lipid composition and enzyme activities in the sera of STZ-induced hyperglycemic rats.
누에 유래 실크 세리신이 당뇨성 흰쥐의 혈당 및 지질 농도 개선에 미치는 영향
김한수 ( Han Soo Kim ),성종환 ( Jong Hwan Seong ),이영근 ( Young Guen Lee ),( Cheng Liang Xie ),신지문 ( Ji Moon Shin ),윤호동 ( Ho Dong Yoon ) 한국식품영양학회 2010 韓國食品營養學會誌 Vol.23 No.3
The objective of this study was to assess improvements caused by silk sericin extract in blood glucose and lipid concentrations in the sera of streptozotocin(STZ, 55㎎/㎏B.W., I.P. injection)-induced diabetic rats fed on experimental diets for 5 weeks. Serum concentrations of blood glucose, total cholesterol, atherosclerotic index, LDL, LDL-cholesterol, free cholesterol, cholesteryl ester ratio, triglyceride(TG) and phospholipids(PL) were remarkably higher in the diabetic group(group BSW) and STZ(I.P.)-plus-silk sericin extract group(group ESS) than in the control group(group CG, basal diet-plus-water). However, the serum concentrations of blood glucose, total cholesterol, atherosclerotic index, LDL, LDL-cholesterol, free cholesterol, cholesteryl ester ratio, TG and PL were lower in the ESS group than in the BSW group, whereas the ratio of HDL-cholesterol concentration to total cholesterol and HDL-cholesterol concentration in the ESS group were higher than in the BSW group. The activities of alkaline phosphatase(ALP) and aminotransferase(AST, ALT) in serum were lower in the ESS group than in the diabetic BSW group. The results shown above suggested that silk sericin extract effectively improves blood glucose and lipid concentrations in the sera of STZ-induced diabetic rats.