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RISS 인기검색어
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- 저자 : 성인환(In Whan Soung) (검색결과 5 건)
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자가 면역성 갑상선 질환에서 T - 임파구 아형의 분포에 관한 연구
허홍근(Hong Keun Heo),한현석(Hyeon Seok Han),김삼용(Sam Yong Kim),성인환(In Whan Soung),노흥규(Heung Kyu Ro),이복희(Bok Hee Lee) 대한내과학회 1987 대한내과학회지 Vol.32 No.6
N/A The study was intended to clarify any quantitative abnormalities of peripheral blood T-lymphocyte subsets in autoimmune thyroid diseases using monoclonal antibodies by immunofluorescence technique. 1) Mean percentages of helper and suppressor T- lymphocytes in normal controls were 43.2±9.5%, 29.7± 7.7% respectively. Mean ratio of percentage of helper T-lymphocytes to that of suppressor T-lymphocytes was 1.52±0.44. 2) Mean percentagen of helper and suppressor T-lympohcytes in hyperthyroid Graves disease without medication(29.0±8.3, 21.7±6.7) was significantly de- creased as compared with normal controls. 3) Mean percentages, of helper and suppressor T-lymphocytes in euthyroid Graves' disease on treatment (41.4±9.5, 25.6±7.6) were not significantly different from those of normal contols. 4) Mean percentages of helper and suppressor T-lymphocytes in Hashimoto's thyroiditis (35.2±11.6, 23.5±5.1) were significantly decreased as compared with normal controls. 5) Mean ratios of percentage of helper T-lymphocytes to that of suppressor T-lymphocytes in three groups (l. 47±0.68, 1.78±0.77, l.62±0.73) were not significantly different from that of normal controls. The results of the present study show that abnormalities in T-lymphocyte subsets exist in patients with autoimmune thyroid disease and it could be used as an idex of response to therapy. Further studies on the implication of the decrement of helper T-lymphocytes in these patients will be pursued.
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최시완,정진옥,강승식,성인환,박종훈 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.1
Background : Noninvasive attemps to identify left ventricular relaxation have been hampered because relaxation rate, left atrial filling pressure, and chamber compliance are the major determinants of peak early velocity and filling rate. This study was perfomed to evaluate the relation between the velocity of flow propagation and left ventricular relaxation by using pulsed doppler echocardiography to analize flow propagation in the left ventricle. Method : By using pulsed Doppler echocardiography, the velocity of left ventricular flow propagation was measured from the distance and time difference of flow wave along the long axis propagation of left ventricular inflow during early filling in normal subjects (n=30), and M-mode echocardiographic data were obtained to evaluate mitral annulus long axis movement (mitral annulus relaxation rate) which represents left ventricular relaxation. Results : the peak early velocity was not related to mitral annulus relaxation rate, but, the velocity of flow propagation was related to mitral annulus relaxarate (P<0.005) in normal subjects. Conclusion : the velocity of flow propagation during early filling seems to be highly dependent on the mitral annulus relaxation rate and could be an important noninvasive tool in studying diastolic function.
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악성종양에서 혈청 비타민 B12 , 엽산 및 Ferritin 의 진단적 의의
김삼용,노흥규,이복희,문윤성,성인환 대한핵의학회 1987 핵의학 분자영상 Vol.21 No.1
In order to evaluate the clinical significances of the serum vitamin BM(12), folate and ferritin levels in patients with malignant tumors, the levels were measured in 10 normal control subjects, 70 patients with malignant tumors, 7 patients with liver cirrhosis and 25 patients with other benign diseases. The results are as follows: 1) In normal control subjects, mean serum values for vitamin B12, folate and ferritin level were 588.80± 131.58 pg/ml, 5.59±1.52 ng/ml and 89.22±42.78 ng/ml retrospectively. 2) There was no significant difference in serum levels between patients with benign diseases and normal control subjects. 3) The serum vitamin B_(12) and ferritin levels in patients with liver cirrhosis were significantly higher than in normal control, and the serum folate levels in these patients were lower than in normal control subjects. 4) The serum vitamin B12 and ferritin levels in patients with malignant tumors were significantly higher than in normal control subjects, and the serum folate levels in these pents were significantly lower than in normal control subjects. The above results suggest that the serum vitamin B_(12) and ferritin may be useful as tumor markers in patients with malignant tumors.
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고혈압 환자에서 도플러 심초음파를 이용한 좌심실내 혈류 전파 속도 측정
최시완,김준경,정준용,류정곤,정진옥,강승식,성인환,전은석,김영건 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.1
Background : Early detection and prevention of cardiac dysfunction is an important goal in the management of hypertensive patients. Doppler echocardiography was used to evaluate the pattern of left ventricular diastolic filling, however, filling indices from mitral sampling are not always nfluenced by factors related to left ventricular relaxation properties. Present study was performed to evaluate the relevance of propagation velocity to patients with hypertension by using pulsed Doppler echocardiography. Method : By using pulsed Doppler echocardiography, the velocity of left ventricular flow propagation velocity was measured from the distance and time difference of flow wave alcng the long axis propagation of left ventricular inflow during early filling in hypertensive patients (n=30 ), and M-mode echocardiographic data were obtained to evaluate mitral annulus long axis movement. Results : The values of E/A ratio, deceleration time, and left ventricular mass index were 0.82 + 0.18, 211 ± 55 msec,152 ±23 gr/m^2 respectively, and those of mitral ann ulus relaxation rate and left ventricular flow propagation velocity were 6.0 ±1.1 cm/sec and 62 ±17 cm/sec respectively. Flow propagation velocity was correlated to Doppler profiles such as E/A ratio ,r=0.47), deceleration time (r= -0.63) and mitral annulus relaxation rate (r=0.87) and also to left ventricular mass index (r= -0.69). Conclusion : left ventricular propagation velocity measurement by using pulsed Doppler echocardiography could be an important noninvasive tool in studying left ventricular diastolic function in patients with hypertension.
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