Changes of Glomerular Basement Membrane Components in Vacor - induced Diabetic Nephropathy

선영덕(Young Duk Seon),이태희(Tai Hee Lee),이민철(Min Cheol Lee) 대한내과학회 1998 KIRI Weekly(주간포커스) Vol.67 No.-

급성 골수성 백혈병의 관해유도치료에서 Idarubicin을 포함한 복합 항암요법

김형준,선영덕,문범,염충호,황태주,서순팔 최신의학사 1995 最新醫學 Vol.38 No.10

당뇨병환자에서의 수면장애

조재현,최은진,강호철,이태희,정민영,이대호,박상선,선영덕 대한당뇨병학회 1994 Diabetes and Metabolism Journal Vol.18 No.3

간호이미지에 관한 조사 연구 : 의사, 간호사, 병원직원, 일반인을 대상으로

김금희,김묘경,권선옥,김성숙,김영미,류보영,선영신,안미경,정선덕,한형숙 병원간호사회 1999 임상간호연구 Vol.5 No.1

Nursing care includes physical, psychological and environmental aspects of the patient. It observes the patient in various phases, confirms and intervenes his problems, so that the patient can maintain and improve his health status. Nursing should be performed according to the concept of total care. Currently, in Korea, there are many factors which prevent the total nursing care from being properly implemented : the lack of a constitutional support system, insufficient hospital environments, knowledge and and technique in special field and an inadequate understanding of nursing care. In addition, the patient doesn't acknowledge nursing as a professional job and even nurses have a negative image of their own jobs. For that reason, it is necessary to establish the positive image of a nurse in order to improve and develop a nurses' status to a professional level. The purpose of this survey is to evaluate the image of nursing and to get a grasp for the ideal way of performing it. To achieve this, we surveyed the people who are related and have an impact on nursing, such as doctors, hospital workers and patients. The contents of this survey include 8 questions in socio-populational characteristics, 39 questions dealing with the image of a nurse which they usually have, 35 questions in how to achieve the ideal image of nursing. The reliance rate of the sample was .959 by the Chronbach's a value. The period of the survey was from 9.4. 1998 to 9.14. 1998. We surveyed 1,000 people including 122 doctors, 212 nurses, 185 hospital workers and 211 patients. Among those samples, 731 people responded to the survey (73.1 %). The survey was analyzed by PC-SAS. The results are as following. 1. Compared were the differences between the positive image of a nurse among the groups. The highly scored answers in all groups are as following : "nursing is a rewarding job", "physically tiring", "a nurse is busy all the time", "nursing contributes to the improvement of the public health". Meanwhile, the highly scored answers in nurses' group but lowly scored answers in other groups are as following ; "a nurse has high responsibilities", "respect others", "humane", "understanding". There are answers which got low scores in the nurse group but high ones in other groups : "nursing is technical and passive", "nurses overvalue themselves", "have high understanding". The last group of answers is one to which all groups gave low scores, although there were some differences among the groups : "nursing is a independent job", "a nurse has high social status", "keeps good relationship with other workers", "they want their children to be a nurse". The differences between the positive image of a nurse among the groups were similar(F=47.72, P= .0001). Among 39 questions, the total scores of the nurses's group was 128.72, the patients' group was 125.47, the hospital workers' group was 118.42, and the doctors' group was 113.99. 2. Also compared were the differences between how the groups rate a nurse's performance and the positive image of a nurse. The answers are classified as the following four groups. The answers of first group got high scores in all groups : "use respect terms to a patient", "wear neat and clean uniform", "explain to a patient in layman terms". The answers of the second group got high scores in nurses' group but low scores in other groups : "be responsible and accurate", "show interest to a patient", "take care of a patient with conscience". The answers of the second group got low scores in nurses' group but high scores in other groups : "be proud to be a nurse", "keep a good relationship among nurses". The answers of the third group got the low scores in all groups : "smile although you are busy", "answer sincerely to the same repeated questions", "a nurse should be highly dedicated to the job", "handle the patient's requests with independence", "actively attend meeting with doctors". The results in the performance rate of positive image of nursing among the groups were similar(F=59.56, P= .0001). The highest score was the nurses' group(126.49), the score of patients' group was(120.90), the score of hospital workers' group was(106.74), the score of doctors' group was(103.71). 3. The differences between the image of nursing and the performance was that the image of nursing was similar in the nurses' group whether they were married or not(F=5.75, P= .0174), but there were some differences depending upon the respondent's age. In the patients' group and the doctors' group, the result were similar but, in the hospital workers' group, there were some differences in the nurse's image according to their ages. In the nurses' group performance rate of the positive image of nursing was a little different according to the nurse's ages(F=2.80, P= .0413), the older have a higher score. In the hospital workers' group, there were some differences depending on their ages (F=2.71, P= .0476). On the other hand, in the doctors' group and the patients' group there were no differences in results.

혈소판 응집능에 미치는 인슐린의 in vitro 효과에 관한 연구

박철주(Cheol Ju Park),조재현(Jae Hyun Cho),강호철(Ho Cheol Kang),선영덕(Young Duck Sun),양승원(Seung Won Yang),정민영(Min Young Chung),이태희(Tai Hee Lee) 대한내과학회 1996 대한내과학회지 Vol.51 No.1

N/A Objectives: It has been suggested that functional abnormalities of platelets play a role in the pathogenesis of diabetic macro- and microangiopathy. Platelets obtained from diabetic patients have been shown to exhibit increased sensitivity to aggregating agents. It was reported that insulin influence on platelet and the long term insulin deficiency might account for the enhanced platelet aggregability frequently observed in diabetic patients. Our aim in this study was to clarify the influence of insulin on platelets in vitro. Methods: We investigated the effects of insulin on platelets response by incubating PRP(platelet rich plama) at 37℃ with different concentrations of the insulin for 5 or 30 min before adding the aggregating agents. Insulin final concentratons were 40, 100μIU/ml, assuming that the basal insulin concentration of PRP is 10 μIU/ml. The responses of platelets to ADP(adenosine diphosphate) and collagen were examined under basal conditions and after the addition of insulin, and they were quantified as the maximal aggregation(M) and T1/2(time consumed to reach 50% of the maximal aggregation). Results: 1) The subjects aged 27.4±2.5(mean±SE) years with body weight 62.5±6.3 kg. 2) The maximal aggregation of the control platelet in response to ADP(60.3±2.7%) was significantly reduced after PRP incubation for 30 min with 40 μIU/ml insulin(52.7±2.7%, 100 μIU/ml insulin(48.7±3.2%) (p<0.01). 3) The T1/2 of the control platelet in response to ADP(30.9±1.9sec) was significantly increased after PRP incubation for 30 min with 40pIU/ml insulin (36.6 ±1.7sec), 100 p μIU/ml insulin(38.3±1.7sec) (p<0.01). 4) The maximal aggregation of the control platelet in response to ADP(60.3±2.7%) was significantly reduced after PRP incubation for 5 min with 100 μ IU/ml insulin(56.9±2.5%), PRP incubation for 30 min with 100 μIU/ml insulin(48.7+3.2%)(p<0.01). 5) The T1/2 of the platelet incubated for 5 min in response to ADP(31.9±2.1sec, 32.5±2.0sec) was significantly increased after 30 min of incubation(36.6 ±1.7sec, 38.3±1.7sec) at 40μIU/ml, 100μIU/ml insulin concentration(p<0.01). 6) The maximal aggregation of the control platelet in response to collagen (63.9±2.8%) was significantly reduced after PRP incubation for 30 min with 40 p IU/ml insulin(58.3±3.0%), 100μIU/ml insulin(55.1±3.3%) (p<0.01). 7) The maximal aggregation of the control platelet in response to collagen(63.9±2.8%) was significantly reduced after PRP incubation for 5 min with 100 μIU/ml insulin(57.8±2.9%), PRP incubation for 30 min with 100 μIU/ml insulin(55.1±3.3%)(p<0.01). Conclusion: Insulin reduces the platelet response to ADP, collagen in vitro, especially in 30 min PRP incubation at same concentration.

자율신경병증을 동반한 인슐린비의존형 당뇨병환자에서 식도 및 위기능장애에 관한 고찰

조재현(Jae Hyun Cho),강호철(Ho Chul Kang),선영덕(Young Duk Sun),양승원(Seung Won Yang),박철주(Chul Ju Park),최은진(Eun Jin Choi),박상선(Sang Sun Park),이대호(Dai Ho Lee),정민영(Min Young Chung),이태희(Tai Hee Lee),송호천(Ho Chun Song 대한내과학회 1995 대한내과학회지 Vol.49 No.4

N/A Objectives: This study was performed to examine the usefulness of the following measurements in evaluating the gastrointestinal motility disturbance in diabetic patients: RGR (Remaining Gastric Radioactivity), GET (Gastric Emptying Time), RER (Remaining Esophageal Radioactivity) and ETT (Esophageal Transit Time) using radianuclide isotope in a liquid diet as well as in a solid diet. Methods: Forty eight non insulin dependent diabetic patients (NIDDM) complaining of gsstrointestinal symptoms were divided into two groups: NlDDM without autonomic neuropathy (Group II, n =21) and NIDDM with autonomic neuropathy (Group III, n=27), and compared with healthy control subjects (Group I, n=51). In each group, ETT, RER, RGR and GET after taking a solid or a liquid diet were measured by the use of radionuclide iso tope. Results: 1) ETT of group III after taking a liquid diet was 24.8±2.76sec, which was significantly longer than those of group I (8.3±0.80sec) and II (8.8±0.48 sec) (p<0.001). 2) ETT of group III after taking a solid diet was 49.20±3.81sec, which was significantly longer than those of group I (18.40±2.32sec) and II (19.75±1.68sec) (p<0.001). 3) RER of group III after taking s liquid diet was 37.2±7.72%, which was significantly higher than those of group I (9.3±0.50) and II (8.3k0.48) (p<0.005). 4) RER of group III after taking a solid diet was 37.84+10.55%, which was significantly higher than those of group I (4.10±0.46%) and II(5.32±0.81 %) (p<0.005). 5) GET of group III after taking a liquid diet was 33.6±2.17min, which was significantly longer than those of group I (21.5±6.70min) and II (26.1±0.40min) (p<0.05). 6) GET of group UI after taking a solid diet was 114.2±8.03min, which was significantly longer than those of group I (61.4±3.65min) and II (60.6±5.21min) (p<0.001). Conclusion: The measurements of ETT as well as GET, using a liquid and a solid diet, are helpful for the evaluations of disorders of esophagogastric motility in patients with diabetic autonomic neuropathy.

낭종성 갑상선 결절에 대한 Minocycline 경화요법의 효과

양승원(Seung Won Yang),박철주(Chul Ju Park),이정훈(Jeong Hoon Lee),박재홍(Jae Hong Park),이재우(Jae Woo Lee),정동진(Dong Jin Chung),정민영(Min Young Chung),이태희(Tai Hee Lee),선영덕(Young Duk Seon) 대한내과학회 1998 대한내과학회지 Vol.55 No.1

N/A Objectives: We studied the efficacy and safety of repeated aspiration therapy and minocycline sclerotherapy for cystic thyroid nodules in the euthyroid patients and the factors which might appear to influence the outcome of therapy. Subjects and Methods : 114 patients with predominantly cystic thyroid nodules were studied. All of the patients underwent the first aspiration therapy, and patients with recurrent cystic lesions after the first aspiration treatment underwent repeated aspiration therapy or additive minocycline sclerotherapy. The patients were followed up ultrasonically 1 and 3 months, and every three month thereafter after the treatments. Results : In 106 patients of 114 patients, cumulative success rate of the treatments was 54.6%. Cumulative success rate of only aspiration treatments(n=81) was 45.1%, 83 patients of 114 patients was recurred after the first aspiration therapy, In these patients, Cumulative success rate of repeated aspiration treatments(n=58) was 24.1%, Cumulative success rate of additive minocycline sclerotherapy(n=25) was 88.0%. Treatment modalities and longest diameter of the lesions significantly influenced the outcome of the treatments. The effect of the larger longest diameter of cystic thyroid nodule would tend to reduce the cummulative success rate, and the cutoff point of the longest diameter was 4.5 cm. There were no significant adverse effects except for transient pain around the injection site in 12 patients (46%). Cytologic study showed 4 (3.5%) of 114 patients to he malignant. Conclusion : Minocycline sclemtherapy of cystic thyroid nodules is a useful and tolerable non-operative therapeutic method in patients with recurrent cystic thyroid nodules after repeated aspiration therapy. The size of a cystic thyroid nodule influence the outcome of aspiration therapy but may not influence the outcome of minocycline sclerotherapy.

대학교수의 경력별 직무역량 요구분석과 지원 방안

송해덕(宋海德),장선영(張善英),김연경(金姸京) 서울대학교 교육연구소 2013 아시아교육연구 Vol.14 No.4

본 연구의 목적은 대학 교수의 우수한 직무수행을 위해 요구되는 역량을 규명하고, 규명된 역량을 향상시킬 수 있는 지원방안을 모색하는 것이다. 연구 목적을 달성하기 위해 첫째, 문헌분석 및 전문가검토를 통해 대학교수의 직무역량군을 도출하였다. 둘째, 서울에 소재한 한 대학의 교수 207명을 대상으로 사전에 개발된 직무역량에 관한 설문조사를 실시하였다. 셋째, 수집된 자료는 t-검증, Borich의 요구도 공식에 적용, The Locus for Focus 모델을 활용하여 분석한 후 최종 우선순위 역량을 도출하였다. 분석결과는 설문에 응한 교수 전체와 교수경력별(10년 미만, 10년 이상 20년 미만, 20년 이상)로 구분하여 도출되었으며, 그 결과는 다음과 같다. 첫째, 교수경력을 구분하지 않고 교수 전체를 대상으로 요구분석을 실시한 결과, ‘학생이해’, ‘동기부여’, ‘수업전달’, ‘창의적 사고’, ‘융복합적 사고’, ‘의사소통’ 역량이 최우선으로 고려해야 할 직무역량으로 도출되었다. 둘째, 경력별로 실시된 요구분석 결과, ‘동기부여’, ‘수업전달’, ‘창의적 사고’, ‘융복합적 사고’가 모든 경력의 교수들에게 공통으로 고려해야 할 직무역량으로 도출되었다. 이밖에 경력이 10년 미만의 교수들에게 ‘학생이해’, ‘교육과정 이해’, ‘리더십’ 역량이, 경력이 10년이상 20년 미만인 교수들에게는 ‘학생이해’, ‘교수전문성’, ‘의사소통’ 역량이, 경력이 20년 이상인 교수들에게는 ‘교수전문성’, ‘의사소통’이 직무역량으로 도출되었다. 이러한 결과를 기반으로 경력별 관련 직무역량을 향상시킬 수 있는 지원방안과 시사점이 제안되었다. The purpose of this study was to identify competencies that are required for conducting university faculties" job performance and to explore support strategies that can be helpful in improving the identified competencies. To achieve the purposes, first, university professors" core job competencies were identified by literature reviews and delphi meetings. Second, a survey was administered with 207 professors at a university in Seoul, Korea. Third, collected data were analyzed by t-test, Borich need assessment formula, and the Locus for Focus model. The identified competencies were prioritized according to their importances. Additional data analysis based on the level of teaching experience (less than 10 years, 10-20 years, over 20years). followed. The results are as follows: First, six competencies were identified from all faculty members. They included ① understanding students, ② stimulating students’ motivation to learn, ③ instructional content delivery, ④ creative thinking, ⑤ convergent thinking, and ⑥ communication. Second, analysis by the level of teaching experience shows that all faculty members perceive four competencies as important regardless of their teaching experiences. The competencies included ① stimulating students’ motivation to learn, ② instructional content delivery, ③ creative thinking, and ④ convergent thinking. In particular, faculty members with less than 10 years of teaching experience perceive three competencies as important. They included ‘understanding students’, ‘understanding curriculums’, and ‘leaderships’. Faculty members with 10 to 20 years of teaching experience perceived three competencies as important. They included ‘understanding students’, ‘communication’, and ‘teaching expertise. Faculty members with over 20 years of teaching experience perceived two competencies as important. They included ‘communication’ and ‘teaching expertise. Support strategies and implications were suggested for each group of faculty members based on the findings.

학습자 참여형 교육공무원 집합교육 교수학습모형 개발

송해덕,장경원,장선영 한국교육방법학회 2013 교육방법연구 Vol.25 No.4

교육공무원들이 교육 현장에서 일어나는 문제들에 대한 문제해결 역량을 양성하기 위해서 학습자 중심 교육이 강조되고 있다. 그렇지만 교육공무원 교육을 집합형 교육으로 진행하는 경우 학습자 중심으로 운영하는 데에는 현실적 한계가 제기되어 왔다. 이에 본 연구에서는 교육공무원을 대상으로한 집합 연수를 학습자들이 중심이 된 교육으로 운영할 있도록 쉽게 활용할 수 있는 참여형 교수학습설계모형을 개발하고, 운영결과를 함께 제시하여 프로그램의 효과성을 검증하였다. 이를 위해 교육공무원의 전문성에 기반을 둔 긍정적 탐구접근, 실제과제해결을 위한 액션러닝접근, 협력적 지식생성을 위한 집단지성 관점에서 교수학습설계요소를 추출하였다. 구체적인 교수학습활동 요소들은 학습주제와 관련된 학습자들의 성공경험도출, 성공경험과 연관된 학습내용제시, 학습내용 적용 기회부여, 개별적 실천계획 수립, 팀 구성원들과의 협의를 통한 계획의 구체화, 업무현장 실천 지원방안수립의 순으로 계열화되어 제시되었다. 본 교수학습설계모형에 따라 교육과학기술연수원의 두 가지 연수과정을 개발하여 연수과정을 운영한 결과, 연수 참여자들은 학습참여 유도 효과와 만족도에서 높은 효과를 가지는 것으로 인식하였다. 끝으로 향후 집합형 교육공무원 연수 과정개발을 위한 시사점과 과제들이 제시되었다. There are growing interests on learner-centered education to improve competencies that help educational government employee to solving problems in educational settings. However, there are difficulties in managing learner-centered education in gathering type training settings due to practical limitations. Thus, this study develops a instructional design model that help designers to easily develop a learner-centered education for gathering training for educational government employees and examined the effectiveness of the model. For this, design elements are extracted from related design approaches such as appreciative inquiries, action learning, and collective intelligences. The model included a sequential learning events that starts from appreciating learners’ success experiences, presenting learning contents with the learners’ experiences, providing practical situations in which learners apply learned experiences, planning individual action plans, further planning in action plans through team members’s reviews, and establishing support plans in worked places. Two educational training programmes were re-designed based on this instructional design model. Participants in this programmes reported that they perceived the programmes as participatory and satisfactory. Finally, implications and future tasks were suggested based on these findings.

식품첨가물 기준규격 관리

권용관(Yong Kwan Kwon),최장덕(Jang Duck Choi),김민식(Min Shik Kim),임호수(Ho Soo Lim),장선영(Sun Young Chang),김문숙(Moon Sook Kim),문귀임(Gui Im Moon),홍기형(Ki Hyoung Hong),홍진환(Jin Hwan Hong),김명철(Moung Chul Kim) 한국식품과학회 2007 식품과학과 산업 Vol.40 No.4