광대역 통신 서비스를 위한 광가입자망 기술

서완석,유강희,김용환,Seo, Wan-Seok,Yu, Gang-Hui,Kim, Yong-Hwan 한국전자통신연구원 1987 전자통신 Vol.9 No.2

본고에서는 선진 각국에서 활발히 진행중인 광가입자망 개발에 관한 기술동향과 1987년중에 제작될 애널로그 광가입자 시스팀, 앞으로의 연구과제인 디지틀 광가입자 시스팀에 관련된 광대역 서비스의 종류 및 전송량, 망구조, 광대역과 협대역 정보의 다중화 방식, 광대역 다중화 방식에 대해 기술하였으며, 가입자망의 발전단계에 대해 언급하였다.

암과 관련된 수면장애

서완석,Seo, Wan-Seok 대한수면의학회 2009 수면·정신생리 Vol.16 No.1

Sleep problems and disorders are common in patients with cancer. Sleep of the cancer patients is affected by various factors, including thermoregulatory changes associated with chemotherapy and radiotherapy, cancer related symptoms, such as pain, fatigue, and emotional difficulties. As one of the most common symptoms in cancer patients, fatigue is positively correlated with sleep difficulties. Cytokine is also frequently associated with chemotherapy and radiotherapy. It provokes excessive daytime sleepiness and hypersomnia. Medications for controlling pain, depression, and anxiety can affect sleep of the cancer patients. Medications as well as behavior therapy are reported to be effective for controlling sleep problems, and the physicians need to be accustomed to use the modalities appropriately. This paper reviews causative factors, evaluation, and management of sleep problems and disorders, experienced by cancer patients.

소아에서의 기면병

서완석,Seo, Wan-Seok 대한수면의학회 2011 수면·정신생리 Vol.18 No.1

Childhood narcolepsy is one of the underdiagnosed diseases even the first symptoms often appear in childhood. Making diagnosis through history taking is not always easy because the symptoms of childhood narcolepsy are different from those of adulthood. Diagnostic laboratory tests such as sleep studies, tests for human leukocyte antigens, cerebrospinal fluid hypocretin measurement should be considered when the child has excessive daytime sleepiness without cataplexy. Treatment approach should be start as early as possible to avoid secondary academic, emotional difficulties. Both pharmacological and non-pharmacological management, and close cooperation between parents and school teachers should be maintained. In the near future, childhood narcolepsy can be a key to understand the pathogenesis of narcolepsy.

불면증의 행동치료 및 광치료

서완석,Seo, Wan-Seok 대한수면의학회 2003 수면·정신생리 Vol.10 No.1

Many people suffer from chronic insomnia. Inappropriate sleep causes attention difficulties, decreased work efficiency, and increased traffic accidents and disasters. Evaluating the precise causes of insomnia prior to treatment is very important, because chronic insomnia can be a secondary symptom of other medical, psychiatric, and sleep disorders. Medication and behavior therapy are not exclusive of each other, and both treatments are beneficial to some patients, but currently many physicians and patients tend to be dependent only on medication. While long-term medication causes various degrees of dependency, tolerance, and withdrawal symptoms, behavior therapy has a stable effect over a long period. Behavior therapy is one of the most important treatment modalities for chronic insomnia. It shortens sleep latency, and decreases frequency of awakening during sleep. The rationale and practice of currently used behavior therapy and light therapy will be reviewed in this study.

Olanzapine 사용과 연관되어 당뇨병성 케톤산증이 발생한 14세 양극성 장애 남아의 사례

서완석(Wan Seok Seo),김진성(Jin Sung Kim) 대한생물치료정신의학회 2007 생물치료정신의학 Vol.13 No.2

We reported an olanzapine-associated transient diabetic ketoacidosis and diabetes mellitus case of a 14-year-old boy with Bipolar disorder. He has been relatively stable with 10㎎ of olanzapine but, he had severe weight gain, from 52㎏ to 113.6 in 3 and a half years. He was lethargy and complained dry mouth, coughing, insomnia from since 7days before admission. He was transferred to emergency room because of mentality change. Important laboratory findings were as follows:PH 7.289 at ABGA, serum glucose level 1,179㎎/dL, ketone 5.6m㏖/L. He was diagnosed as DM and DKA and supplied fluid & insulin. His mentality and all laboratory findings except serum glucose level were become to normal in three days. His symptoms of bipolar were man-aged with topiramate, gquetiapine, aripiprazole instead of olanzapine. This is the first case report of olnazapine-associated diabetic ketoacidosis in pediatric patient with bipolar disorder in Korea. This case report suggested that when olanzapine was used in pediatric population, regular monitoring of serum glucose level and body weight change, understanding of early warnings signs of DM and DKA should be needed.

악성뚜렛 증후군의 치료대안

서완석(Wan Seok Seo) 대한생물치료정신의학회 2012 생물치료정신의학 Vol.18 No.2

Tourette syndrome(TS) is a chronic psychiatric disorder which begins during childhood and it is negatively affect the patients’ emotional, academic and their occupational activities. Neurobiological basis is very important in occurrence and treatment of TS. The psychiatrists who evaluate and treat TS should understand the neural basis of symptom onset, mechanism of medication and non-medicational treatment as well as psychological, developmental, and behavioral knowledge of TS. Nowadays, use of first, second generation antipsychotic medication is common in clinical situation but some sorts of tics are not well controlled. I reviewed brief mechanisms and effectiveness of some medications such as dopamine agonists, GABA agents, alpha antagonists, and botulinum toxin. I also introduced some non-medicational methods such as electroconvulsive therapy, transcranial magnetic stimulation, and deep brain stimulation.

한국의 주의력결핍/과잉행동장애 아동에서 Oros-Methylphenidate의 임상적 효능과 부작용에 대한 단기간의 다기관 개방연구

서완석(Wan Seok Seo),이종훈(Jong Hun Lee) 대한생물치료정신의학회 2007 생물치료정신의학 Vol.13 No.2

Objectives:This study was conducted to evaluate the clinical efficacy and adverse effects of Oros-Methylphenidate(MPH) in children with attention deficit hyperactivity disorder. Methods:A four week, open-label trial with forced flexible dosing strategy of Oros-methylphenidate was performed with 83 children with ADHD. For parental evaluation, parental version of SNAP-IV and visual analogue scale (VAS) were applied at baseline and endpoint. Every week CGS-S and adverse events chart were applied by the research clinicians. Baseline and endpoint body mass index(BMI) and blood pressure also compared. Results:Significant improvement in VAS and SNAP-IV were demonstrated between baseline and week four. Significant improvement of CGI-S in every weeks after trial of Oros-MPH, especially in first two weeks. 78.3% of the participants experienced at least one adverse effects. Anorexia and insomnia were most common adverse effects, which lasted for about two weeks. Significant decrease in BMI and significant elevation of diastolic blood pressure were observed. Conclusion:This study showed that Oros-MPH significantly reduced symptoms of ADHD in Korean children with ADHD, especially early period of medication trial. Meanwhile, many children also experienced adverse effects such as anorexia, insomnia. Moreover, increase in diastolic BP suggested that cautious evaluation of cardiac function should be needed.

대구지역 일개 초등학교를 대상으로 한 소아 수면문제에 대한 예비연구

서완석(Wan Seok Seo),구본훈(Bon Hoon Koo),김민지(Min Ji Kim),노영환(Yeung Hwan Rho),성형모(Hyung-Mo Sung),신지현(Ji-Hyun Shin) 대한소아청소년정신의학회 2008 소아청소년정신의학 Vol.19 No.3

Objectives: The purpose of this study was to investigate the prevalence of sleep problems in Korean elementary school children and the differences in sleep problems elated to their school grade and gender. Methods : One public elementary school in Dae-gu, Korea as randomly selected. And, parents who agreed to participate this study were asked to complete a modified version of Tucson Childrens Assessment of Sleep Apnea screening questionnaire (TuCASA). Results: The most common sleep problem was falling asleep in vehicle (44.2%) and the prevalence rate of this problem differed by school grade. The prevalence rate of falling asleep while watching TV before 8 P.M. (8.0%), daytime fatigue (21.9%) and nocturnal enuresis during the past 6 months (5.3%) were significantly differed by school grade. The prevalence rate of falling asleep while doing home work, falling sleep during a lesson, snoring and bruxism were 12.6%, 1.0%, 26.7% and 13.2% respectively. Although these rates did not show any differences between grades, snoring as more in boys and daytime fatigue was more in girls. Conclusion: This study demonstrates that many elementary school children may have various sleep problems. Lower grade elementary schoolers had sleep problems which related to euro-developmental factors, whereas higher grade elementary schoolers had sleep problems related to sleep deprivation and stress. Finally, more female schooler showed signs of fatigue or sleepiness than male schoolers.

한국인 폐쇄성수면무호흡증후군 환자의 임상특성과 한국판 Epworth Sleepiness Scale의 임상적 유용성

서완석(Wan Seok Seo),손효일(Hyo Il Son),구본훈(Bon Hoon Koo),이광헌(Kwang Heun Lee),송창진(Chang Jin Song),곽경필(Kyung-Phil Kwak),송민재(Min Jae Song) 대한생물치료정신의학회 2005 생물치료정신의학 Vol.11 No.2

목적 : 국내에서 폐쇄성수연무호흡중후군(obstructive sleep apnea syndrome, OSAS) 환자의 임상특성과 위험인자를 밝혀내고 한국판 Epworth Sleepiness Scale의 임상적 유용성 및 폐쇄성수면무호흡중후군의 중중도와의 연관성을 알아보기 위해 본 연구를 시행하였다. 방법 : 2002년 1월 3일부터 2004년 12월 31일까지 영남대학교 신경정신과 수면클리닉을 방문한 환자중 무호흡-저호흡지수가 5 이상이며 주기적 사지운동 증후군, 하지불안 증후군, 수면제 복용, 기면병, 알코올 남용한 경우를 제외한 158명을 대상으로 시행하였다. 검사 일주일 전부터 수면일지를 완성하여 평균수면시간이 최소 6시간 이상인 경우 본 실험에 포함하였으며 수면다원검사를 시행하기 전 Epworth Sleepiness Scale을 작성하였다. 결과: 폐쇄성수연무호흡증후군의 중중도와 유의하게 연관된 인자는 desaturation index와 최저산소포화도였다. 체질량지수, 평균산소포화도, 초기산소포화도 및 한국판 Epworth Sleepiness Scale과 폐쇄성수면무호흡증후군의 중증도와의 사이에서는 유의한 연관성을 보이지 않았다. 결론 : 폐쇄성수연무호흡증후군에서 Epworth Sleepiness Scale의 임상적 유용성에 관한 연구는 추후 다양한 방법으로 이루어져야할 것이다. Objectives: The study has been performed in order to find out the clinical characteristics and risk factors of patients with obstructive sleep apnea syndrome in Korea, the clinical usefulness of Epworth Sleepiness Scale On Korean edition) and the correlation between Epworth Sleepiness Scale and the severity of obstructive sleep apnea syndrome. Methods: Among the patients who have visited sleep clinic, department of Neuropsychiatry from Yeongnam University from Jan. 3, 2002 to Dec. 31, 2004, 158 patients whose apnea-hypopnea index was more than 5 and who had no cases of periodic limb movement syndrome, restless leg syndrome, intake of sleeping pills, narcolepsy and the abuse of alcohol have been the subjects of study. Sleep diary was completed one week before the investigation and that the average sleeping time is at least more than 6 hours is included in this experiment and Epworth Sleepiness Scale was completed before the performance of polysomnography. Results: The factors related significantly to the severity of obstructive sleep apnea syndrome were desaturation index and lowest oxygen saturation. There was no significant correlation between body mass index, mean oxygen saturation, baseline oxygen saturation and Epworth Sleepiness Scale(in Korean edition) and the severity of obstructive sleep apnea syndrome. Conclusion: In this study, desaturation index and lowest oxygen saturation reflect the severity of obstructive sleep apnea syndrome. The further study on the clinical usefulness of Epworth Sleepiness Scale in obstructive sleep apnea syndrome should be performed in various ways in the future.

지역순환형 친환경성 축산폐수처리기술

서완석(Wan Seok Seo) 한국수처리학회 2002 한국수처리학회지 Vol.10 No.3

N/A Livestock wastewater is one of the major environmental pollution problems in Korea. With its high organic and nutrients loads, its optimum treatment is not easy in spite of the good potential technology of recycling. HYCEM was developed to meet the requirements of the treatment and recycling of the livestock wastewater. HYCEM consists of pretreatment process by centrifuge, biological treatment process of HYCEM-AN(hybrid anaerobic digester), nitrification reactor, and SBR reactor, and post-treatment process by physicochemical polishing process. HYCEM has several alternative cases for application as follows : Firstly. it could treat the livestock wastewater to meet the effluent standard of local water system. Secondly, it could be used as an alternative treatment for the effluent that could be further treated in a municipal wastewater treatment plant. Finally, the effluent of HYCEM-AN could be applied to farmland as a liquefied fertilizer with high quality. Therefore HYCEM is a friendly-environmental technology that could solve the problem of treatment of livestock wastewater and coincidentally could use the effluent as a liquefied fertilizer.