국소 침윤마취법을 이용한 족지조직 유리 피판술

서동린,박승하,이병일,Seo, Dong-Lin,Park, Seung-Ha,Lee, Byung-Ihl 대한미세수술학회 2007 Archives of reconstructive microsurgery Vol.16 No.2

This study was designed to introduce free toe tissue transfer using infiltration method of local anesthetic agent. Four toe pulp tissues were transferred to reconstruct finger tip defect in four patients who were not suitable for general anesthesia. Two flaps taken from the lateral side of the great toe was used for reconstruction of thumb defect and two flaps from the medial side of the second toe for resurfacing of the index and fifth finger. Flap sizes were various from $2.0{\times}2.0\;cm^2$ to $1.6{\times}4.0\;cm^2$. Anesthesia was induced by infiltration of 2% lidocaine hydrochloride (with 1:100,000 epinephrine) with dilution of normal saline in same volume unit, as like as in ordinary digital block. All vessels were anastomosed within 2 cm of distance from the proximal margin of the defect. Whole operative procedures were carried out by one team. All flaps were successfully taken without complication. The average operation time was 4 hours 10 minutes. The amount of anesthetic agent used in whole operative procedures was roughly 4 mL in the toe, 8 mL in the finger, and 12 mL totally. In conclusion, free toe tissue transfer using infiltration method of local anesthetic agent would be good strategy for finger tip reconstruction in the patient not suitable for general anesthesia.

비정형적 명세와 정형적 명세간의 상호변환 지원시스템

서동린,위금숙,이금석 동국대학교 대학원 1993 大學院硏究論集-東國大學校 大學院 Vol.23 No.-

The purpose of this paper is to address the issue of integrating informal and formal requirements specification techniques. In this paper we present the combination of SA(Structure Analysis) and VDM(Vienna Development Method). We specially focus on the specification transformation from DFD to VDM-SL and vice versa, and the development of the transformation supporting tools. Such a combination has the following advantages: · The specifier is given structural guidance for the construction of a formal specification of the system. The formal specification should then be used as a starting point of the further development of the system. · The DFD can be a more convenient means to explain the formal semantics of the VDM-SL specification.

전신조사방사선치료에서 열형광선량계를 이용한 선량 측정과 체질량지수에 관한 고찰

서동린,김연수,김대섭,윤화룡,백금문,곽정원,Seo, Dong-Rin,Kim, Yeon-Soo,Kim, Dae-Sup,Yoon, Hwa-Ryong,Back, Geum-Mun,Kwak, Jung-Won 대한방사선치료학회 2011 대한방사선치료학회지 Vol.23 No.2

Purpose: The aim of study is to expose a more uniform dose depending on the relationship between a body mass index in patients who underwent radiation therapy and an acquired dosimetric information by using a thermoluminescent dosimeter. Materials and Methods: Since 2006 to August 2011 we investigated 28 people who underwent radiation therapy were enrolled in AMC. Each patient was measured on the head, neck, chest, abdomen, pelvis, thigh, knee joint, and ankle joint using the thermoluminescent dosimeter. The measurement value of each points compared with the prescribed center point, abdominal point, and dose measurements of points on which to base the abdomen and the patient's body mass index (BMI) were compared with reference point, abdomen dose. Results: 28 patients on prescribed dose in the abdomen by which the center point, an average dose was $100.6{\pm}5.5%$, and the other seven measuring points with the average maximum difference among the head, neck, chest, pelvic, thigh, knee, and ankle were $92.8{\pm}4.2%$, $97.6{\pm}6.2%$, $96.4{\pm}5.5%$, $102.6{\pm}5.3%$, $103.4{\pm}7.9%$, $95.8{\pm}5.9%$, $96.1{\pm}5.5%$. The relationship of abdominal point dose and the patient's body mass index (BMI) was analyzed a scatter plot, and the result of linear relationship analysis by regression method, the regression of the dose (y) was -1.009 BMI (x) plus 123.3 and coefficient of determination ($R^2$) was represented 0.697. Conclusion: The total body irradiation treatment process was evaluated the dose deviation and then the prescribed dose by which the average abdominal dose was satisfied with $100.6{\pm}5.5%$. Results of the relationship analysis between BMI and dose, if we apply the correction value for each patients, it can be achieved more uniform dose delivery.

전산화단층모의치료기를 이용한 경기관지 근접치료환자의 치료계획에 관한 고찰

서동린,김대섭,백금문,Seo, Dong Rin,Kim, Dae Sup,Back, Geum Mun 대한방사선치료학회 2013 대한방사선치료학회지 Vol.25 No.1

목 적: 경기관지 근접치료에 이용되는 2차원 치료계획의 경우 환부를 확인하는 과정에서 종양의 위치 파악에 어려움이 있어 정확한 치료계획 분석이 어려울 수 있다. 이에 본 연구에서는 전산화단층모의치료기를 이용한 3차원 치료계획으로 환자의 치료계획을 비교 분석하고자 한다. 대상 및 방법: 2012년 6월 본원을 내원한 환자를 대상으로 전산화모의치료장비(Lightspeed RT, GE, USA)와 Oncentra Brachy planning system (Nucletron, Netherland)를 사용하여 3차원 치료계획을 시행하여 2차원 치료계획과 비교 분석하였다. 결 과: 분할 조사로 시행되는 경기관지 근접치료에서 매회 카테터의 위치 파악이 치료계획 상에서 확인 되었고, GTV 용적은 $3.5cm^3$, $3.3cm^3$로 확인 할 수 있었다. 또한 종양의 선량분포 파악이 용이하여 GTV에 대하여 첫 번째 치료 시 처방선량의 92%, 두 번째 치료 시 88%로 파악되어 선량전달 오차를 파악할 수 있었다. 결 론: 2차원 치료계획을 통한 근접치료의 문제점을 보완하기 위하여 치료용적과 선량분포의 정확한 파악과 분석이 가능한 3차원 치료계획으로 검증이 필요하고, 선량전달 오차를 정량적으로 파악하여 치료계획에 반영하는 과정이 필요하다고 생각된다. Purpose: Transbronchial brachytherapy used in the two-dimensional treatment planning difficult to identify the location of the tumor in the affected area to determine the process analysis. In this study, we have done a comparative analysis for the patient's treatment planning using a CT simulator. Materials and Methods: The analysis was performed by the patients who visited the hospital to June 2012. The patient carried out CT-image by CT simulator, and we were plan to compare with a two-dimensional and threedimensional treatment planning using a Oncentra Brachy planning system (Nucletron, Netherland). Results: The location of the catheter was confirmed the each time on a treatment planning for fractionated transbronchial brachytherapy. GTV volumes were $3.5cm^3$ and $3.3cm^3$. Also easy to determine the dose distribution of the tumor, the errors of a dose delivery were confirmed dose distribution of the prescibed dose for GTV. In the first treatment was 92% and the second was 88%. Conclusion: In order to compensate for the problem through a two-dimensional treatment planning, it is necessary to be tested process for the accurate identification and analysis of the treatment volume and dose distribution. Quantitatively determine the dose delivery error process that is reflected to the treatment planning is required.

배양하지 않은 지방조직세포를 이용한 창상피복

서동린,한승규,전경욱,김우경 대한성형외과학회 2008 Archives of Plastic Surgery Vol.35 No.6

Purpose: Skin and soft tissue defect is one of the major challenges faced by plastic surgeons. Adipose derived stromal cells, which can be harvested in large quantities with low morbidity, display multilineage mesodermal potential. Therefore, adipose derived stromal cells have been met with a great deal of excitement by the field of tissue engineering. Recently, Adipose derived stromal cells have been isolated and cultured to use soft tissue restoration. In order to apply cultured cells for clinical purpose, however, FDA approved facilities and techniques are required, which may be difficult for a clinician who cultures cells in a laboratory dedicated to research to utilize this treatment for patients. In addition, long culture period is needed. Fortunately, adipose derived stromal cells are easy to obtain in large quantities without cell culture. The purpose of this study is to present a possibility of using uncultured adipose derived stromal cells for wound coverage. Received April 2, 2008 Revised May 29, 2008 Accepted June 20, 2008 Address Correspondence: Seung-Kyu Han, M.D., Department of Plastic Surgery, Korea University Guro Hospital, 97 Guro-dong, Guro-gu, Seoul 152-703, Korea. Tel: 02)2626- 3333/Fax 02)868-6698/E-mail: pshan@kumc.or.kr *본 논문은 2007년 제63차 대한성형외과학회 추계학술대회에서 구연발표 되었음. Methods: Seven patients who needed skin and soft tissue restoration were included. Five patients had diabetic foot ulcers, 1 patient got thumb amputation, and 1 patient had tissue defect caused by resection of squamous cell carcinoma. The patients’ abdominal adipose tissues were obtained by liposuction. The samples were digested with type I collagenase and centrifuged to obtain adipose derived stromal cells. The isolated adipose derived stromal cells were applied over the wounds immediately after the wound debridement. Fibrin was used as adipose derived stromal cells carrier. Occlusive dressing was applied with films and foams and the wounds were kept moist until complete healing. Results: One hundred to one hundred sixty thousand adipose derived stromal cells were isolated per ml aspirated adipose tissue. All patients’ wounds were successfully covered with the grafted adipose derived stromal cells in a 17 to 27 day period. No adverse events related to this treatment occurred. Conclusion: The use of uncultured adipose derived stromal cells was found to be safe and effective treatment for wound coverage without donor site morbidity.

폐암 환자의 전신 정위적 방사선 수술시 정확한 SET UP에 대한 고찰

서동린,홍동기,권경태,박광호,김정만,Seo, Dong-Rin,Hong, Dong-Gi,Kwon, Kyung-Tea,Park, Kwang-Ho,Kim, Jung-Man 대한방사선치료학회 2004 大韓放射線治療技術學會誌 Vol.16 No.2

목적 : 전신 정위적 방사선 수술환자 치료 시 환자의 set up을 정확히 확인하고 평가하는 것은 치료 성적을 좌우 하는데 중요한 요소이다. 특히 폐암 환자의 경우 호흡 등에 의한 종양의 움직임으로 인해서 L-gram이나 EPID를 이용하여 정확한 위치를 확인하는데는 여러 가지 어려움이 있다. 이러한 문제점들에 대하여 verification system(exactrac)을 이용하여 set up의 정확성을 확인해 보고자 한다. 대상 및 방법 : Body frame(elekta, sweden)을 이용하여 전신 정위적 방사선 수술을 받는 폐암 환자 6명을 대상으로 (ABC tool을 사용한 환자 5명과 사용 안한 환자1명) 기존의 L-gram과 EPIDs로 image를 획득하여 Ant, Lat image를 비교하여 환자의 set-up을 확인하고 CT에서 얻은 DRR image와 Verification system(exactrac)의 X-ray image를 얻어서 두image를 3차원적으로 fusion하여 그 좌표 값(vertical, longitudinal, lateral)을 분석하고 기존의 방법과의 차이를 확인하였다. 결과 : L-gram과 EPIDs로는 정확한 좌표 값보다는 주관적으로 Set up의 정확성 여부를 판단하여 치료할 수 있었지만 Verification system(exactrac)을 이용하여 확인한 결과 치료환자의 Set up 전, 후의 좌표 값(vertical, longitudinal, lateral)이 0.5cm이내에 포함되는 것을 볼 수 있었고 좌표 값의 차이를 시각적이고 객관적으로 평가할 수 있어서 Set up의 정확성을 판단하는 데 유용했다. 결론 : Verification system(exactrac)을 사용하면 환자의 Set up이 정확한 지 치료 전 또는 중간에도 시각적인 확인이 가능한 장점이 있지만 기존의 방법보단 확인과정이 조금 복잡하고 CT scan 시 3mm 이내로 해야 하며 X-ray image가 선명하게 나타나야 된다는 단점이 있다. 이러한 문제점만 해결된다면 Set up의 정확성을 쉽게 확인할 수 있어서 치료 시 많은 도움이 되리라고 생각된다. Purpose : What confirm a patient's set-up precisely is an important factor in stereotactic radiosurgery Especially, the tumor is moved by respiration in case of lung cancer. So it is difficult to confirm a exact location by L-gram or EPID. I will verify a exact patient's set-up about this sort of problem by verification system(exactrac 3.0) Materials and Methods : The patient that had lung cancer operated on stereotactic radiosurgery is composed of 6 people. The 5 patients use an ABC tool and 1 patient doesn't use it. I got such a patient's L-gram and EPID image by Body frame(elekta, sweden), compared Ant. image with Lat. one, and then confirmed a set-up. I fused DRR image of CT and X-ray image of Verification system(exactrac 3.0) 3 dimensional, analyzed the coordinate value(vertical, longitudinal, lateral), and then confirmed a difference of existing method. Results : In case of L-gram and EPID, we judge an exact of the patient's set-up subjectively, and on we could treat the patient with radiation. As a result of using Verification system(exactrac 3.0), coordinate value(vertical, longitudinal, lateral) of patient's set-up was comprised within 5mm. We could estimate a difference of the coordinate value visually and objectively. Consequently, Verification system(exactrac 3.0) was useful in judging an exact patient's set-up. Conclusion : In case of Verification system(exactrac 3.0), we can confirm an exact patient's set-up at any time whenever, However, there are several kinds of the demerit. First, it is a complex process of confirmation than the existing process. Second, thickness of CT scan slice is within 3mm. The last, X-ray image has to have shown itself clearly. If we solve this problem. stereotactic radiosurgery will be useful in treating patients why we can confirm an exact patient's positioning easily.

삼각형 V-Y피판 및 장사방형피판을 이용한 매몰귀의 교정

이준문,서동린,동은상,윤을식,Lee, Joon-Moon,Seo, Dong-Lin,Dhong, Eun-Sang,Yoon, Eul-Sik 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.5

Purpose: Cryptotia is a congenital deformity in which the upper third of the auricle is buried under the temporal skin. It is rare in Caucasians, yet it is more common in Asians. Although a variety of methods to treat cryptotia have been introduced, there is still no acceptable single procedure that can successfully manage this deformity in its entity. We present a triangular V-Y advancement flap and rhomboid flap for correcting cryptotia that can overcome the diverse shortcomings of the conventional methods. Methods: This operative method was used to correct 18 auricles in patients ranging in age from 4 to 33 years. A triangular flap was prepared over the auricle by making a skin incision according to Ohmori's method. Then a rhomboid flap with a side length of about 8 to 10 mm that sets the lower portion as a pedicle in the anterior region was prepared to supplement the contracted portion of the helix. The cartilage deformity was corrected by the banner flap or the radiating cartilage incisions with cartilage graft or high density polyethylene graft. Results: We have treated 16 patients with severe cryptotia using this method and have obtained good aesthetic results. All cases showed widened scaphoid fossa and smooth triangular fossa of antihelix. There were no major postoperative complications, such as necrosis or infection of the flaps. Conclusion: Correction of cryptotia using the triangular V-Y advancement flap and rhomboid flap is useful a method for certain conditions, when a severe contraction of the helix is present.

Analysis of inter-fraction and intra-fraction errors during volumetric modulated arc therapy in Pancreas Ca

조영필,서동린,홍택균,강태영,백금문,홍동기,윤인하,김진산,Jo, Young Pil,Seo, Dong Rin,Hong, Taek Kyun,Kang, Tae Yeong,Beck, Geum Mun,Hong, Dong Ki,Yun, In Ha,Kim, Jin San Korean Society for Radiation Therapy 2014 대한방사선치료학회지 Vol.26 No.2

목 적 : 췌장 환자 방사선 치료 중 기점(Fiducial) 대상 내부 및 외부 종양 움직임의 오차를 정량화 하고자 한다. 또한 cone beam computed tomography (CBCT) 를 기반으로 호흡 시 췌장의 움직임 분석하고자 한다. 대상 및 방법 : 용적 세기변조 회전조사 (V-MAT)를 적용, 정위적 방사선 치료를 국소 진행성 췌장암 환자 11명을 대상으로 하였다. CBCT 및 직교 투시이미지를 적용하여 기점(Fiducial Marker)의 Inter, intra-fraction 움직임 변화를 치료 전, 치료 진행 시 분석하였다. 결 과 : 치료 후 프로토콜을 오프라인 교정 프로토콜을 사용하여, CBCT 와 직교투시 간의 평균 오차(범위)는 0.0(-1.7~4.0), 0.3(-0.5~3.0) and 0.0(-4.1~6.6)mm 측방 (LR), 세로 (AP) 및 종 방향 (SI) 이였다. 무작위 Inter-fraction Setup 오차 결과는 -0.1, -2.3 and -1.1 mm: 95% Fiducial포함 마진은 각 9.9, 7.8, 12.5mm로 수식되었다. 결 론 : 위 분석으로 뼈 일치 정렬 후 잔류 불확실성이 있으며, SI 방향에 큰 임의의 움직임은 적합한 여백이 필요하다. 주변 내부 장기를 보호, 내부 장기 문제점을 최소화, 호흡편차를 고려, 치료 시 정기적으로 측정하여야 한다. Purpose : To assess target motion during radiotherapy by quantifying daily setup errors and inter-fractional and intra-fractional movements of pancreatic fiducials. Materials and Methods : Eleven patients were treated via stereotactic body radiotherapy (SBRT) with volumetric modulated arc therapy. Bony setup errors were calculated using cone beam computed tomography (CBCT). Inter-fractional and intrafractional fiducial (seed) motion was determined via cone beam computed tomography (CBCT) projections and orthogonal fluoroscopy. Results : Using an off-line correction protocol, setup errors were 0.0 (-1.7-4.0), 0.3 (-0.5-3.0), and 0.0 (-4.1-6.6) mm for the left-right, anterior-posterior, and superior-inferior directions respectively. Random inter-fractional setup errors in the mean fiducial positions were -0.1, -1.1, and -2.3 mm respectively. Intra-fractional fiducial margins were 9.9, 7.8, and 12.5 mm, respectively. Conclusion : Online inter-fractional and intra-fractional corrections based on daily kV images and CBCT expedites SBRT of pancreatic cancer. Importantly, inter-fractional and intra-fractional motion needs to be measured regularly during treatment of pancreatic cancer to account for variations in patient respiration.

고 병렬성을 갖는 새로운 RAID 구조에 관한 연구

명원식,서동린 (사)디지털산업정보학회 2007 디지털산업정보학회논문지 Vol.3 No.2

전문대학 교육지표 연구

강성원,차갑부,서동린,김평구,류근민,문종철 한국고등직업교육학회 1999 한국고등직업교육학회 학술대회 논문집 Vol.1999 No.11