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白鼠肝壞死 및 肝硬變症과 唾液腺病變과의 相關關係에 關한 實驗的 硏究
邊榮男(Young Nam Byun) 대한구강악안면외과학회 1977 대한구강악안면외과학회지 Vol.3 No.1
In order to observe the salivary gland in relation with liver necrosis and cirrhosis, 98 male albino rats of 3 to 4 months old, weighing 150 to 190gm, were selected and divided into two groups. 1. Control group: 14 rats were fed on a ready-made diet and sacrifiecd at intervals of 1, 3, 5, 5, 7, 14 and 28 days, the liver and the salivary gland were extracted. 2. Experimental group: 84 rats were fed on the same diet as the control group. At intervals of every 3 days, a single dosage(0.1cc/100gm bodyweight) of CC1₄, were injected into the peritoneal cavity. The experimental groups are further subdivided on the basis of duration of injections. a. Group 1(21 rats): total number of injections two times in the period of 6 days. b. Group 2(21 rats): total number of injections four times in the period of 12 days. c. Group 3(21 rats): total number of injections six limes in the period of 18 days. d. Group 4(21 rats): total number of injections eight times in the period of 24 days. Each experimental group was then sacrificed at the intervals of 1, 3, 5, 7, 14 and 28 days. As in the control group, the salivary gland and the liver were extracted, at the time of sacrifice without resort to anesthesia. The extracted glands and liver were immediately fixed in 10% neutral Formaline solution for 24 hrs. Via paraffin embedding, the tissuse were prepared in 4-5μ in thickness. H & E. stain was used in the liver tissue whereas in the preparation of the salivary gland PAS & Alcian blue were used in additon to H & E stain. The results of this study were as follows: 1) In histopathologic study of the liver, it was concluded that in the group 1, only the mild necrosis was observed. The group 2, moderate necrosis was observed but no evidence of the fibrotic changes were seen. However, in group 3, severe necrosis was seen and fibrotic changes were partially seen in the 28th day sacrificed animals. The group 4 resulted in the liver cirrhosis. 2) Very little differences if any on the salivary glands of group with mild and moderate liver necrosis when compared to that of the control group. 3) In the salivary gland of severe necrosis group, the swelling in the regoin of acini and the hydrophic degeneration in the epithelial cells of the striated duct were observed. In the duct of submaxillary gland infiltrations of inflammatory cells were noticed. PAS and Alcian blue reaction were observed to be more decreased in comparison to the control group. 4) The hydrophic changes in the acini and the epithelial cells of the striated ducts were more severe in the group 4 when compared to the group 3. Further PAS and Alcian blue reaction were observed to be more decreased in the group 4, in comparison to the group 3.
변영남,배양일,송노헌 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.4
AVMs is not a neoplasm, but a congenital developmental anomalies. In oral and maxillofacial area, the high recurrence rate and more facial disfigurement give a difficult problem to surgen and patient. Conventional treatment modality nowadays is presurgical embolization and surgical resection. In treatment planning, we consider the possibility of complete surgical resection and the esthetics of soft tissue reconstruction. But, two things are very difficult to achieve. We present a patient with AVMs in left upper lip, he had presurgical embolization with Ivalon and Bucrylate, and conservative surgical procedure. So we present this possible treatment modality.
변영남,정필훈,윤영호,김종철 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.4
Angiolymphoid hyperplasia with eosinophilia(ALHE) is benign subcutaneous lesion that primarily affects head and neck region. It is characterized by single or multiple nodules in the subcutaneous tissue associated with eosinophilia in the peripheral blood. Kimura's disease, originally reported by Kimura et al., is similar lesion with ALHE in the clinical and histopathological aspects. There has been considerable controversy about the relation between Kimura's disease and ALHE. IN Korea, 26 cases of Kimura's disease and ALHE have been reported since 1975. We present a case of recurred ALHE occurring on the left cheek in a 58-year-old woman. Including this case, we summarized all cases that were reported as Kimura's disease or ALHE in Korea through literature review. We also give an outline of clinical and histopathological characteristics of cases reported in Korea.
김종원,김유진,변영남,김종철,김명진,이종호,명훈,Kim, Jong-Won,Kim, Yu-Jin,Pyun, Yung-Nam,Kim, Jong-Chull,Kim, Myung-Jin,Lee, Jong-Ho,Myoung, Hoon 대한악안면성형재건외과학회 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.1
본 교실에서는 가족력을 가지며, 하악에 다발성으로 재발된 치성각화낭종의 증례가 있어 보고하는 바이다. 환자들은 한 가족의 어머니와 두 자녀였으며 그중 어머니와 딸의 경우 낭종적출후 수차례의 재발을 보여 딸은 앞으로도 수술을 예정하고 있다. 낭종이외의 다른 기저세포모반증후군의 증거는 보이지 않았다. 처치로서 어머니와 딸의 경우 낭종적출술을 시행하였고 아들의 경우 낭종적출후 결손부의 크기가 커서 동종골이식을 시행하였다. 현재 어머니와 아들의 경우 재발은 보이지 않고 있으나 향후 지속적인 구강검사를 통해 관리예정이며 유전학적인 검사도 고려하고 있다. A family is presented in which multiple odontogenic keratocysts have been expressed. 3 members of the two generations of family with features of multiple keratocysts, suspected basal cell nevus syndrome have been investigated. The proband, 19-year-old woman and her mother, and her brother suffered from these cysts and two female patients' disease have been recurred multiply though careful treatments. Close attention to the family and routine follow up will alert the clinician to its recurrences and genetic counseling and serial screening for the development of other symptoms, that is malignant skin carcinoma etc.