페암의 방사선치료

배훈식,박찬일 한국의학사 1985 診斷과治療 Vol.5 No.9

고관절 외상의 진단에 있어서 전산화단층촬영술의 장점 -자험 3례를 통한 고찰-

배훈식 대한영상의학회 1984 대한영상의학회지 Vol.20 No.1

Computed tomography has been advocated as an adjunct to conventional radiography in the evaluation of pelvic bone fractures and traumatic dislocations of the femoral head. Author compared and analysed the CT and plain radiographic findings of 3 consecutive adult patients in whom acetabular or femoral head injuries were suspected or demonstrated on initial radiographs. The result니 were as follows: 1. Computed tomography was conventient and precise mehtod in evaluating the patient with hip trauma. 2. Computed tomography was helpful in detecting intraaraticular osseous fragment, interposed soft tissue, and widening of the joint space which was not evident on plain radiographs. 3. Computed tomography permitted better evaluation of assciated injuries in soft tissue and viscera in the pelvic and retroperitoneal cavity, and also gave information about other associated fractures. 4. Computed tomography was superior for the evaluation of posterior acetabular rim and medial portion of the acetabulum. 5. Computed tomography was helpful for evaluating the pressence or absence of intraarticular osseous fragments after reduction of the dislocated hip.

후두손상에서의 전산화단층촬영술의 역할

배훈식 대한영상의학회 1984 대한영상의학회지 Vol.20 No.1

Computed tomography of the larynx represents a major advance in laryngology. Even in severe injury the larynx can be examined easily and conveniently by CT at the same time as the brain and facial structures without moing the patient, who need only lie down and breathe quietly during the study. Computed tomography permitted a much more detailed apraisal of laryngeal dysfunction in patients with blunt laryngeal trauma (3 cases) and strangulation injury (2 cases). Computed tomography of the larynx undoubtedly played a determinant role in patient management. Computed tomography was helpful in evaluating the laryngeal cartilages and deep spaces of the larynx which was difficult to examine by the laryngoscope. Follow-up computed tomography made it possible to evaluate the postoperative results.

The Role of IMRT(Intensity Modulated Radiation Therapy) in Head and Neck Cancer

배훈식 대한두경부종양학회 2001 대한두경부종양학회 학술대회 논문집 Vol.2001 No.2

Advances in Radiation Therapy for Hypopharyngeal Cancer

배훈식 대한두경부종양학회 2002 대한두경부종양학회 학술대회 논문집 Vol.2002 No.1

하부요로 손상환자의 방사선학적 소견

배훈식,배원경,조온구 대한영상의학회 1981 대한영상의학회지 Vol.17 No.3

During the period of 4 years from July , 1976 to June, 1980 the raiological and clinical evaluation had been made on 102 patients suffered from lower urinary tract injuries which were confirmed by the radioloigcal examination and operation. The results were as follows : 1. Age distribution of the total 102 patients (87 males and 15 females) was broad form 4 to 72 years. And most of the patient were in the age group of 20 to 49 years. 2. The most common cause of injury was traffic accident (67.6%) nest blunt trauma, saddle injury, fall down respectively. 3. 46 patients of bladder injury were as follows : intraperitoneal rupture in 17, extraperitoneal rupture in 12, and contusion in 14. 4. 74 patients of urethral injury were as follows : membranous portion in 37 , bulbous portion in 31, prostatic portion in 3, and penile portion in 2. Most of the cases showed extravasation of contrast media. 12 cases showed extravasation with venous intravasation. 5. contusion or extraperitoneal rupture of the bladder, membranous urethral injury, and concommitent bladder and urethral ruptures were frequently assocciated with pelvic bone fracture, Intraperitoneal ruptures of the bladder and solitary ruptures of the bulbous urethra were infrequently associated with pelvic bone fracture. 6. Late seqeulae of the lower urinary tract injury tract injury were stricture, fistula and stone formation.

암치료에서의 방사선치료의 역할 : 치험 1년에 대한 분석

배훈식 한림대학교의료원 1991 人間科學 Vol.15 No.12

항문 종야에 대한 항암화학방사선 치료

배훈식,김종훈,최상규,오도훈,박영석 한림대학교의료원 1994 人間科學 Vol.18 No.4

마우스공장 소낭선의 방사선 효과에 온열요법의 병용이 미치는 실험적 연구

배훈식,김정진 한양대학교 의과대학 1986 한양의대 학술지 Vol.6 No.1

The experimental study was undertaken to assess the effect of combined hyperthermia and radiation on the mouse jejunal crypts using the microcolony survival assay. Heating was pplied for 30 min a temperatures of 41℃, 42℃, 43℃ after radiation. The results were as follows: 1. After 30 min heating at 41℃, the surviving numbers of crypt per circumference of the jejunum were 130±3 (Mean ±SD) and 140±3 at 42℃, 142±4 at 41℃, compared with a control value of 144±4. Heperthermia alone at 43%C showed cytotoxic effect on the jejunal mucosa. 2. The surviving crypt around the jejunal circumference were asymmetrically distributed with maximum survival adjacent to the mesenteric attachment at 43℃. This pattern of crypt survival is thought to be a consequence of heat dissipation by the blood flow. 3. The predominant effect of combined hyperthermia and radiation was o displace the radiation survival curves of jejunal crypt stem cells to the left without a significant change in slope. Thermal enhancement ratio (TER) was 1.12 at 41℃, at 1.10 at 42℃ and 1.39 at 43℃. The effect of radiation on the jejunal crypts was maximally enhanced at 43℃. 4. Hyperthermia at 43℃ combined with irradiation was thought to be ideal in clinical application according to the results of this experiment.

External Radiation Therapy Combined with Hyperthermia in the Carcinoma of Extrahepatic Biliary System

배훈식(Hoon Sik Bae) 대한방사선종양학회 1992 Radiation Oncology Journal Vol.10 No.1

From January 1986 to September 1990, 7 patients with carcinoma of the extrahepatic biliary system received external radiation therapy combined with hyperthermia. Of the 3 patients with extrahepatic bile duct cancer, two were primary cholangiocarcinoma and one was metastatic peripancreatic carcinoma. Of the 4 patients with carchinoma of the gallbladder, two were locoregionally advanced and unresectable carcinoma and the remaining two were local-regional recurrence after cholecystectomy, They were all pathologically proven adenocarcinoma. The radiation dose received ranged from 3000 cGy/2weeks to 5040cGy/7 weeks. The hyperthermia was done once or twice a week and 4 to 12 sessions in total. The tumor response was confirmed by T-tube cholangiography. percutaneous transhepatic cholangiography and CT scan. 6 out of 7 (86%) showed partial regression of the tumor. The median survival time was 7 months (range 4~11 months). 6 out of 7 patients were dead: one died of septicemia, 4 of primary disease, one of distant metastases. Only one out of 7 patients is still alive but new metastatic lesion was found. There was not any treatment related deaths. there was also no evidence of treatment related problems with liver, stomach and duodenum, although the observation period was short. 1986년 1월부터 1990년 9월까지 7예의 간외담도계 암 환자를 대상으로 외부 방사선치료와 온열치료를 병행하였다. 7예중 3예는 간외담도암으로 이중 2예는 원발성 담도암이었고 1예는 위암에서 담도주위로 전이된 암이었다. 7예중 나머지 4예는 담낭암으로 이중 2예는 담낭 절제후 국소적으로 재발된 암이었고 나머지 2예는 원발성 담낭암이었다. 그리고 7예는 모두 선암으로 확인 되었다. 조사된 방사선의 양은 3000 cGy/2주 조사한 1예를 제외하고 6예에서는 4500~5040cGY/6~7주 조사되었다. 온열치료는 모든 환자에서 방사선 치료후 30분 이내에 시행되었으며 방사선치료 기간동안 주 1회 내지 2회씩 총 4회에서 12회까지 시행되었다. 치료효과의 판정은 T-관 담도촬영술, PTC, 그리고 CT등의 소견으로 하였으며 7예중 6예(86%)에서 부분관해를 보였으며 완전관해는 없었다. 7예중 6예는 4개월에서 11개월 이내 사망하였으며 나머지 1예는 현재 11개월째 생존하고 있으나 치료부위 밖에서 국소전이가 관찰되었다. 그리고 7예환자의 정중생존기간은 7개월이었다. 사망환자 6예의 사망원인으로는 원발성 담도암환자 1예에서 폐혈증, 전이성 담도암환자에서 원격전이, 나머지 4예에서는 원발병소의 진행이 확인되었다. 관찰기간이 짧았으나 모든 환자에서 치료에 잘 적응하였으며 간, 십이지장, 위내의 합병증은 없었고 전이성 담도암 환자에서 일과성 카보닐산혈증이 관찰되었다.