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코호트 기반 조사 공변수 자료의 신뢰도 평가 연구: 원전주변지역주민 역학조사연구
배상혁,박보영,이충민,안윤옥,Bae, Sang-Hyuk,Park, Bo-Young,Li, Zhong-Min,Ahn, Yoon-Ok 대한예방의학회 2010 예방의학회지 Vol.43 No.2
Objectives: We evaluated the reliability of the possible covariates of the baseline survey data collected for the Epidemiological Investigation on Cancer Risk Among Residents Who Reside Near the Nuclear Power Plants in Korea. Methods: Follow-up surveys were conducted for 477 participants of the cohort at less than 1 year after the initial survey. The mean interval between the initial and follow-up surveys was 282.5 days. Possible covariates were identified by analyzing the correlations with the exposure variable and associations with the outcome variables for all the variables. Logistic regression analysis with stepwise selection was further conducted among the possible covariates to select variables that have covariance with other variables. We considered that these variables can be representing other variables. Seven variables for the males and 3 variables for the females, which had covariance with other possible covariates, were selected as representative variables. The Kappa index of each variable was calculated. Results: For the males, the Kappa indexes were as follow; family history of cancer was 0.64, family history of liver diseases in parents and siblings was 0.56, family history of hypertension in parents and siblings was 0.51, family history of liver diseases was 0.50, family history of hypertension was 0.44, a history of chronic liver diseases was 0.53 and history of pulmonary tuberculosis was 0.36. For females, the Kappa indexes were as follow; family history of cancer was 0.58, family history of hypertension in parents and siblings was 0.56 and family history of hypertension was 0.47. Conclusions: Most of the possible covariates showed good to moderate agreement.
배상혁,홍윤철 대한의사협회 2018 대한의사협회지 Vol.61 No.12
Particulate matter is an air pollutant emitted from both natural and anthropogenic sources, and its adverse health effects have been well documented in time-series analyses and cohort studies. The effect size of particulate matter exposure—a roughly 0.5% increase in mortality for each 10 μg/m3 increment of short-term exposure to particulate matter with aerodynamic diameter ≤10 µm and approximately a 10% increase for each 10 μg/m3 increment of long-term exposure to particulate matter with aerodynamic diameter ≤2.5 µm—is small compared to other risk factors, but the exposure is involuntary and affects the entire population, which makes particulate matter pollution an important public health issue. The World Health Organization and Korean government have both established guidelines for particulate matter concentrations, but the Korean guideline is less stringent than that of the World Health Organization. The annual mean concentration of particulate matter in Korea is decreasing, but the trend seems to be slowing. In addition to policy efforts to reduce particulate matter emission, personal approaches such as the use of face masks and air purifiers have been recommended. Personal approaches may not solve the fundamental problem, but can provide temporary mitigation until efforts to reduce emission make progress.
배상혁,권호장 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.3
Purpose: The effects of air pollution on health can vary regionally. Our goal was to comprehensively review previous epidemiologicalstudies on air pollution and health conducted in Korea to identify future areas of potential study. Materials and Methods: We systematically searched all published epidemiologic studies examining the association between airpollution and occurrence of death, diseases, or symptoms in Korea. After classifying health outcomes into mortality, morbidity,and health impact, we summarized the relationship between individual air pollutants and health outcomes. Results: We analyzed a total of 27 studies that provided 104 estimates of the quantitative association between risk of mortality andexposure to air pollutants, including particulate matter with aerodynamic diameter less than 10 μm, particulate matter with aerodynamicdiameter less than 2.5 μm, sulfur dioxide, nitrogen dioxide, ozone, and carbon monoxide in Korea between January 1999and July 2018. Regarding the association with morbidity, there were 38 studies, with 98 estimates, conducted during the same period. Most studies examined the short-term effects of air pollution using a time series or case-crossover study design; only three cohortstudies that examined long-term effects were found. There were four health impact studies that calculated the attributablenumber of deaths or disability-adjusted life years due to air pollution. Conclusion: There have been many epidemiologic studies in Korea regarding air pollution and health. However, the present reviewshows that additional studies, especially cohort and experimental studies, are needed to provide more robust and accurateevidence that can be used to promote evidence-based policymaking.
배상혁,김홍순,강승걸 대한수면의학회 2018 수면·정신생리 Vol.25 No.2
흡연은 많은 질환들에 악영향을 미치는 가장 중요한 요인들 중 하나이다. 이전 많은 연구들이 흡연이 심혈관계질 환, 호흡기질환, 악성종양, 뇌혈관질환 등의 질병을 유발한 다는것을보였다.흡연은이런신체적질환뿐아니라수면 의 질을 나쁘게 하고 수면장애의 발생에도 영향을 준다는 근거들이 축적되고 있다. 이 종설은 흡연과 니코틴이 수면 과 각종 주요 수면장애(불면증, 폐쇄성수면무호흡증, 하지 불안증후군)들과 어떠한 연관이 있는지에 초점을 맞추었 다. 흡연과 수면장애의 관련성에 대해서 보다 확정적인 결 론을 도출하기 위해서는 향후 원인-결과를 확인할 수 있는 보다 잘 계획된 대규모의 연구들이 이루어져야 할 것으로 보인다. 흡연은 중단가능한 행동습관이기 때문에 건강과 수 면의 개선을 위해 금연하는 것이 권고되고 의료인들도 이 에 대한 강조를 지속하여야 한다. Smoking is one of the most harmful causes of disease. Many previous researches have shown that cigarette smoking leads to cardiovascular, respiratory, oncologic, and cerebrovascular diseases. In addition to such adverse effects, the literature in- dicates that cigarette smoking can worsen sleep quality and induce sleep disorders. This review focuses on the relationship between smoking/nicotine and sleep and sleep disorders of insomnia, obstructive sleep apnea, and restless legs syndrome. Because smoking is a behavioral pattern that can be changed, it is important to quit smoking to improve overall health and sleep.
PLD증착 변수에 따른 II-VI족 화합물 ZnO 반도체 박막의 발광 특성 연구
배상혁,윤일구,서대식,명재민,이상렬 한국전기전자재료학회 2001 전기전자재료학회논문지 Vol.14 No.3
ZnO thin films for light emission device have been deposited on sapphire and silicon substrates by pulsed laser deposition technique(PLD). A Nd:YAG laser was used with the wavelength of355 nm. In order to investigate the emission properties of ZnO thin films, Pl measurements with an Ar ion laser a light source using an excitation wavelength of 351 nm and a power of 100 mW are used. All spectra were taken at room temperature by using a grating spectrometer and a photomultiplier detector. ZnO exhibited Pl bands centers around 390, 510 and 640 nm, labeled near ultra-violet(UV), green and orange bands. Structural properties of ZnO thin films are analyzed with X-ray diffraction(XRD).