The Effects of Pulsed Electromagnetic Fields on Blood components, Antioxidant enzymes and Reactive Oxygen in Hyperlipidemic Rats

방현수,정인호,이상덕,Bang, Hyun-Soo,Jeong, In-Ho,Lee, Sang-Deok The Society of Digital Policy and Management 2014 디지털융복합연구 Vol.12 No.7

본 연구는 맥동전자장이 고지혈증 관련 혈액 성분, 항산화 효소와 활성 산소에 어떠한 영향을 미치는 지를 관찰하기 위하여 실시하였다. 실험군은 정상식이군, 고지방식이군과 고지방식이-맥동전자장 적용군의 3군으로 나누었다. 맥동 전자장은 맥동 전자장 에너지 치료기를 이용하였다. 혈액 성분의 검사 항목은 혈당, 유리지방산, 중성지방 및 콜레스테롤, 인슐린이고, 항산화 효소와 활성 산소의 검사는 글루타치온, 글루타치온 환원효소, 크산틴, 과산화지질을 측정하였다. 그 결과 맥동전자장 적용은 혈액 구성성분과 GSH와 GRD를 고지장식이 수준에서 정상식이 수준으로 상승시켰으며, XO와 MDA는 고지방식이 수준에서 정상 식이 수준으로 낮추어 주는 개선효과를 나타내었다. 그러므로 맥동전자장의 적용은 고지혈증 흰쥐의 혈액성분의 변화, 항산화 효소의 증가, 활성 산화의 억제에 효과적인 치료 방법이라 할 수 있다. The present study was aimed to investigate the effects of the application of pulsed electromagnetic fields on the blood components associated hyperlipidemia, antioxidant enzymes and reactive oxygen. The subjects were divided into three groups: General Diet, High fat Diet, High fat diet and pulsed electromagnetic fields. Pulsed electromagnetic field was applied with pulsed electromagnetic energy therapy equipment. The Glucose, free fatty acids, triglycerides, cholesterol and insulin was used to measure hyperlipidemia-related blood components, and the GSH, GRD, XO and MDA was used to measure antioxidant enzymes and reactive oxygen. The applied pulsed electromagnetic field has improved the concentrations of blood components and increasing GSH and GRD, that were decreased due to a high-fat diet and by reducing the increased MDA and XO to a level of general diet group. Therefore, the applied pulsed electromagnetic field can be the effective treatment for changes in the blood composition of hyperlipidemic rats, enhancement of antioxidative activity and the inhibition of reactive oxygen.

진동 적용이 척수 손상으로 유발된 근위축 모델에서의 기능 회복과 BDNF 발현에 미치는 영향

방현수(Bang Hyun-Soo),김훈(Kim Hoon),김진상(Kim Jin-Sang) 한국체육과학회 2008 한국체육과학회지 Vol.17 No.3

The purpose of this study was to identify the effect of vibration on muscle atrophy model lead to spinal cord injury. Twenty-four Sprague-Dawley male rats were operated with spinal cord injury and randomly devided two groups, Control and Experimental groups. Experimental group was applicated two times a day, five days a week and fifteen minutes a session by vibration device. In order to observe the effect of vibration, this study observed BDNF expression in rat lumbar spinal cord after spinal cord injury. In addition, the tilting plane test was measured at each 3, 7, 14, 21 days group. The tilting plane test is gradually increased each group. In 21 days group, there is significant difference between control and experimental group. The immunoreactivity of BDNF in the rat spinal cord was gradually increased in each group. In 21 days group, there is significant difference between control and experimental group.

감각통합운동 프로그램이 경직성 뇌성마비 아동의 운동기능과 기능적 독립성에 미치는 영향

방현수(Bang, Hyun Soo) 한국보건기초의학회 2020 한국보건기초의학회지 Vol.13 No.2

The purpose of this study was to investigate how applying a sensory integration exercise program with children that have spastic cerebral palsy affects the children’s motor function and functional independence. The experiment was conducted on 16 children diagnosed with spastic cerebral palsy. The sensory integration exercise program was conducted in 90 minutes sessions twice a week for 8 weeks. It was divided into four intervals, with each two-week period being counted as one interval. In regards to gross motor functions, there was a significant increase at both 4 weeks of application and 8 weeks of application in the sitting, crawling, and kneeling positions (p<0.05). Among functional independence, in the self-care, sphincter control, mobility, and locomotion categories there was a significant increase at both 4 weeks of application and 8 weeks of application (p<0.05). It was found that a sensory integrated exercise program is an effective therapeutic intervention method to improve the motor function and functional independence, which is a measure of motor function, in children with spastic cerebral palsy.

상상 훈련과 진동 운동의 적용이 수직점프의 수행력에 미치는 영향

방현수 ( Hyun Soo Bang ),정병옥 ( Byeong Ok Jung ),김진상 ( Jin Sang Kim ) 대한물리의학회 2009 대한물리의학회지 Vol.4 No.1

Purpose The Purpose of this study was to investigate the effects of image training and vibration on performance of vertical jumping. Methods Subjects was classified into two groups, which were image training group (n=20) and vibration application group (n=20). The standard methods of each intervention were image training with listening recorded indication for 5 minute and vibration with speed of 1200±200 rpm, Muscle strength was measured using vertical jump performance, Results The vertical jump performance was significantly increased after image training and vibration application (p<.05), however, it was more significantly after image training (p<.05), Conclusion This study showed that image training and vibration application were effective treatment strategy on increase of muscle strength. Therefore, it could be considered as a treatment method in the patients with musculoskeletal disease including fracture, chronic degenerative disease and disuse atrophy.

요부안정화 운동이 만성요통여성 환자의 근활성도와 등속성 근력에 미치는 영향

방현수 ( Hyun Soo Bang ) 대한물리의학회 2015 대한물리의학회지 Vol.10 No.2

PURPOSE: The purpose of this study to investigate the effects of exercise on lumbar stabilization in muscle activity and isokinetic muscle strength of female with chronic low back pain. METHODS: The candidates was chose to twenty women in their 30s and 40s complaining back pain for over 12 weeks and consist of 10 people for lumbar stabilization and general physical therapy group(PL group), another 10 people for general physical therapy group(GP group). Lumbar stabilization exercise was conducted for 8 weeks and was comprised of 60 minutes for two times a week. In order to examine the effects of lumbar stabilization, results in the present study were analyzed maximal voluntary isometric contraction (MVIC) using electromyogram to measure muscle activity and isokinetic performance including peak torque and average power at the pre to post. RESULTS: The following are results in this study. The MVIC and isokinetic muscle strength were gradually increased in all group. As the result of the test of the MVIC and isokinetic muscle strength, the difference of lumbar stabilization and general physical therapy group is statistically more significant than that of general physical therapy group. CONCLUSION: In the present study, results indicate that lumbar stabilization helps to improve the muscle activity and isokinetic muscle strength.

등속성 운동 시 각속도의 변화가 위팔두갈래근의 근력에 미치는 영향

방현수 ( Hyun Soo Bang ),김진상 ( Jin Sang Kim ) 대한물리의학회 2009 대한물리의학회지 Vol.4 No.3

Purpose:The purpose of this study was to investigate the effects of angular velocity on muscle strength of biceps brachii. Methods:Subjects was classified into two groups, which were 60°/sec angular velocity group(n=15) and 240°/sec angular velocity group(n=15). Each group was applied to perform the isokinetic exercises on flexion muscle group for each 10 times in 3 set (3 days per a week for 2 weeks). Muscle strength was measured using peak torque of biceps brachii. Results:The results were as follows: The peak torque was significantly increased after 60°/sec angular velocity isokinetic exercise application(p<05), however, it was not significantly after 240°/sec angular velocity isokinetic exercise application(p>.05). Conclusions:This study showed that 60°/sec angular velocity isokinetic exercise application were effective treatment strategy on increase of muscle strength. Therefore, it could be considered as a treatment method in the athlete and patients with musculoskeletal disease.

밴드저항운동과 순환운동프로그램이 뼈감소증이 있는 여성노인의 신체조성 및 뼈밀도에 미치는 영향

방현수(Bang, Hyun Soo),김동훈(Kim, Dong Hoon) 한국보건기초의학회 2021 한국보건기초의학회지 Vol.14 No.2

The purpose of this study was to investigate band resistance exercise and circuit exercise program for 12 weeks to elderly women with osteopenia affects the body composition and bone mineral density. An experiment was conducted on 12 elderly women diagnosed with osteopenia. Band resistance exercise and circuit exercise program were conducted 3 times a week, 60 minutes per session, for 12 weeks, band resistance exercise and circuit exercise program consisted of warm-up activity, band resistance exercise 20 minutes, rest, circuit exercise 20 minutes, and finishing exercise. For evaluation of body composition, muscle mass, body fat percentage, and body mass index were measured, and bone mineral density was measured. In body composition, there was a significant difference in muscle mass at the 12th week of the experiment (p<0.05), and a significant difference in body fat percentage at the 12th week of the experiment (p<0.05). Also, there was a significant difference in body mass index at 12 weeks (p<0.05). However, although there was a tendency to increase in bone mineral density, there was no significant difference (p>0.05) It was found that the band resistance exercise and circuit exercise program are an effective therapeutic intervention method to improve the body composition and bone mineral density in elderly women with osteopenia.

진동 적용이 좌골신경압좌손상이 유발된 흰쥐의 운동기능과 BDNF발현에 미치는 영향

방현수(Bang Hyun-Soo),김진상(Kim Jin-Sang),정병옥(Jung Byeong-Ok),이윤섭(Lee Yun-Seob) 한국체육과학회 2009 한국체육과학회지 Vol.18 No.2

The purpose of this study was to investigate effects of vibration application on motor function and BDNF expression after crushing nerve injury of rats. Male Sprague-Dawley rats (N=18), 8 weeks age and weight from 250 to 300 g were used for this study. Crush injuries were produced on the right sciatic nerve. Vibration was applied to experimental group (N=9) on injured site at 3, 7 and 13 day. For compare the motor function between control and experimental group, the tilting plane test was measured at each gorup. The expressions of BDNF on S2 segment of spinal cord by immunohistochemistry were used for the result of motor function and peripheral nerve regeneration, respectively. Both gourps were significant increased changes of tilting plane test with the lapse of time, but tilting plane rest score were more significant in experimental group than in control, and this differences were remarkable at 14 days after sciatic nerve crush injury. Between experimental and control group, BDNF expressions after sciatic nerve crush injury were significant different. BDNF expression were non-significant in control group, but experimental group were observed significant increased change of BDNF expression with the lapse of time. These results suggest that vibration application is essential factor for early phase after crushing nerve injury. In conclusion, vibration application was contributed to motor function and nerve regeneration and could be used for nerve injury treatment.

맥동전자장이 불완전 척수손상 흰쥐의 기능회복과 GAP-43의 발현에 미치는 영향

방현수 ( Hyun Soo Bang ) 대한물리의학회 2012 대한물리의학회지 Vol.7 No.3

Purpose This study was designed to investigate the effects of pulsed electromagnetic field on functional recovery and expression of GAP-43 after incomplete spinal cord injury (SCI) in rats. Methods To confirm the damage of SCI and effects of pulsed electromagnetic field, 20 Sprague-Dawley male rats were used and divided randomly 2groups (SCI, PEMF). Incomplete SCI was induced by using modified NYU drop model. After operation, functional recovery test, immunohistochemistry and western blot analysis were measured at 1, 2, 3 weeks. Pulsed electromagnetic field were apply three weeks (one times a day, five days a week and twenty minutes a session). Results In the this study, applications of pulsed electromagnetic field after incomplete SCI induced the significant improvement in functional recovery and expression of neurotrophic factor. The results were as follows; Foot print test, PEMF were significantly decreased than the SCI (p<.05). Expression of GAP-43, PEMF were significantly increased than the SCI at 2 and 3 weeks (p<.05). Conclusion In conclusion, pulsed electromagnetic field were positive effect in functional recovery and expression of GAP-43 after incomplete SCI in rats.

대퇴사두근에 대한 국소적 진동 적용이 수직점프에 미치는 영향

방현수 ( Hyun Soo Bang ),천송희 ( Song Hee Choen ),이현민 ( Hyun Min Lee ),허광호 ( Gwang Ho Heo ),강종호 ( Jong Ho Kang ),김진상 ( Jin Sang Kim ) 대한물리의학회 2008 대한물리의학회지 Vol.3 No.2