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세퍼드에서 ethylene glycol 독성에 관한 연구
박현종,이오형,임채웅,Park Hyun-Jong,Lee Oh-Hyung,Lim Chae Woong 한국동물위생학회 2005 韓國家畜衛生學會誌 Vol.28 No.1
Ethylene glycol (EG) intoxication in dogs can pose a diagnostic challenge. We investigated the effect of a lethal dose of EG to the Shepherd on blood, urine test, and histopathologic observation. Shepherds were treated orally with EG at $10\;m{\ell}/kg$ body weight. Clinically, EG caused the vomition, depression of central brain. Anion gap was increased, which was decreased pH of blood, The blood osmorality was increased at 3 hours, and BUN and creatinine was increased at 24 hour significantly. The pH of urine decreased. The crystal of calcium oxalate appeared at 6 hours. The amount of crystals increased at 12 and 24 hours. Microscopically, the degeneration of proximal tubules were shown at 1 hour and finally progressed as acute tubular nephrosis at 24 hours. These results suggest that the blood and urine test accompanied with histopathological examination be helpful to investigate the EG intoxication.
박현종(Hyun Jong Park),남승우(Seung Woo Nam),노임환(Im Hwan Roe),이문숙(Moon Sook Lee),유 권(Yoo Kweon),이재현(Jai Hyun Lee),명나혜(Na Hye Myong) 대한소화기학회 2001 대한소화기학회지 Vol.38 No.1
Ingestion of foreign bodies occurs commonly in young children and emotionally disturbed individuals. Predisposing factors include decreased palatal sensitivity by dentures, excessive alcohol intake or drug use. Despite the incredible number and variety of objects, most ingested foreign bodies pass through the gastrointestinal tract, but the cases fewer than 1% result in perforation. The clinical manifestations of perforation include peritonitis, abscess, inflammatory mass, fistula, obstruction, and hemorrhage. Because most symptoms mimic the other common intraabdominal conditions, and many patients can not recall the ingested materials, preoperative diagnosis is difficult. The greastest number of perforations occur in appendix, the ileocecal region and Meckel`s diverticula. The remainders are scattered throughout the gastrointestinal tract, with a slightly higher incidence in the sigmoid colon. We present here a case of colonic perforation by an ingested chicken bone presenting as an intraabdominal inflammatory mass. The diagnosis was confirmed by laparoscopic surgery. (Korean J Gastroenterol 2001; 38:53-56)