지금 자치단체에서는 : 『지방행정』시,도 편집위원 통신란 - 경기도(제611호)

박현웅 대한지방행정공제회 2004 地方行政 Vol.53 No.611

Solar fuel production using oxide semiconductor electrodes

박현웅 한국공업화학회 2012 한국공업화학회 연구논문 초록집 Vol.2012 No.1

Fucoidan improves the structural integrity and the molecular stability of b-lactoglobulin

박현웅,김도영,신원선 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.5

b-lactoglobulin (b-lg) was covalently bonded with fucoidan through Maillard reaction at 60 C for 96 h under 79% RH condition. The molecular characters of the conjugate were investigated using fourier transform infrared spectroscopy (FT-IR), atomic force microscopy (AFM), and circular dichroism (CD) spectroscopy. And, its thermal properties, surface activity, and zeta-potential were compared with intact b-lg, b-lg-fucoidan mixture, and fucoidan under different pH conditions. AFM indicated that the conjugate was nano-structured, regular sphericalshaped and generally large sized compared to b-lg-fucoidan mixture. CD spectra and FT-IR showed that tertiary structure of b-lg slightly unfolded, but little change in secondary structure occurred. This explained that glycation under Maillard condition resulted in a molten globule state of b-lg. Differential scanning calorimetry (DSC) data exhibited that fucoidan shifted the temperature of phase transition and improved thermal stability of b-lg molecule. In addition, the conjugate prominently decreased the surface tension with pH-dependency.

Clinical characteristics of acute drug-induced dystonia in pediatric patients

박현웅,곽재령,이지숙 대한응급의학회 2017 Clinical and Experimental Emergency Medicine Vol.4 No.3

Objective Dystonia is a movement disorder in which muscles contract uncontrollably. Acute drug-induced dystonia (DID) can be diagnosed through detailed history taking and physical examination. This study aimed to identify the clinical characteristics of DID in children, which could help emergency physicians diagnose these conditions more efficiently. Methods We reviewed medical records of children aged below 18 years diagnosed with drug-related dystonia after discharge from the emergency department over 10 years. We collected the patients’ age, sex, suspected causative drugs, initial diagnosis of the prescribing physician, duration of drug-taking, diagnostic evaluations, treatment methods, and prognosis. Results Seventy-nine patients were enrolled. The mean age was 11.3±4.9 years (range, 4.0 months to 18.0 years), and 41 patients (51.9%) were boys. The most common cause of DID was gastrointestinal medications in 45 patients (57.0%), followed by antipsychotics in 23 patients (29.1%). Eleven (24.4%) out of 45 patients with DID due to gastrointestinal medications had the initial diagnosis of upper respiratory infection, and seven (30.4%) out of 23 patients with DID due to antipsychotics had the initial diagnosis of non-psychotic diseases. Younger children received more diagnostic procedures and were more frequently admitted. A benzodiazepine (67.1%) was the most common single drug for treatment. Conclusion Physicians should not only acknowledge DID in order to reduce unnecessary workup and admission, but also know that antiemetics and antipsychotics are common causes of DID. Therefore, physicians should try to avoid multidrug prescriptions in children.

현장검사 화학 분석 장비 Piccolo xpress Chemistry Analyzer 성능 평가

박현웅,고대현,김진규,송상훈 대한진단검사의학회 2009 Annals of Laboratory Medicine Vol.29 No.5

Background : Point-of-care (POC) tests are used increasingly due to fast results and simple test procedures, which enables rapid diagnosis and therapeutic monitoring. We evaluated the performance of the Piccolo xpress Chemistry Analyzer (Abaxis, USA) a POC chemistry analyzer. Methods : Fourteen analytes, Na+, K+, Cl-, Ca2+, total carbon dioxide, AST, ALT, total bilirubin, alkaline phosphatase, blood urea nitrogen, creatinine, albumin, total protein, and glucose; were measured simultaneously with a 100 μL of whole blood sample using a Comprehensive Metabolic Reagent disk. Within-run and total precision and linearity were evaluated according to CLSI EP15-A and EP6-A guidelines, respectively. Comparison with a central laboratory chemistry analyzer was performed using 144 patient samples. Results : The coefficients of variations of within-run and total precision were all within 5% for three levels except for total carbon dioxide, ALT, alkaline phosphatase, total bilirubin, and creatinine in low level, and creatinine in middle level. The results of 14 analytes were linear within a commonly encountered range in clinical samples (r2≥0.98). More than 10% of samples in Na+, AST, ALT, glucose, BUN did not satisfy CLIA analytical quality requirement. Conclusions : The Piccolo xpress Chemistry Analyzer can analyze multiple analytes with a minimal amount of whole blood in a short time. It showed an acceptable performance for precision, linearity and comparison with central laboratory analyzer. It can be useful as a screening tests modality in mobile clinics, ambulances, and field clinics for military use, and for pediatric patients from whom enough sample volume is difficult to obtain. 배경 : 현장검사는 신속하고 간편하여 환자의 진단과 치료효 과 판정에 빠르게 적용할 수 있기 때문에 점차 그 적용범위가 늘 어나고 있다. 저자들은 현장검사 화학분석장비인 Piccolo xpress Chemistry Analyzer (Abaxis, USA)의 성능을 평가하였다. 방법 : Comprehensive Metabolic Reagent 디스크에 100 mcL의 검체를 이용하여 14가지 항목(나트륨, 칼륨, 염소, 칼슘, 총 이산화탄소, AST, ALT, 알칼리인산분해효소, 총 빌리루빈, 혈당, 혈액요소질소, 크레아티닌, 알부민, 총 단백질)을 동시에 측정하였다. 검사차례내 정밀도와 총 정밀도는 CLSI EP15-A 에 준하여 평가하였으며, 직선성은 CLSI EP6-A에 준하여 평 가하였다. 중앙검사실 장비와의 상관성은 144개의 환자 검체를 이용하여 평가하였다. 결과 : 검사차례내 정밀도와 총 정밀도의 변이계수(CV)는 낮 은 농도의 총 이산화탄소, ALT, 알칼리인산분해효소, 총 빌리 루빈, 크레아티닌과 중간농도의 크레아티닌을 제외하고 모두 5% 미만이었다. 14가지 항목의 측정값은 임상 검체에서 흔하게 나타나는 범위에서 직선성을 유지하였다(r2≥0.98). 그러나 나 트륨, AST, ALT, 혈당, 혈액요소질소의 경우 CLIA의 수행능 평가 요구조건에 부합하지 않는 검체가 10% 이상인 점은 임상 환경에서 사용 시 주의가 필요하다. 결론 : Piccolo xpress Chemistry Analyzer는 소량의 전혈 로 짧은 시간에 여러 항목을 측정할 수 있다. 정밀도, 직선성, 중 앙검사실 장비와의 상관성은 수용할 만하였다. Piccolo xpress Chemistry Analyzer는 이동식 진료실, 응급 후송차, 군대의 야전 진료소와 많은 양의 채혈이 어려운 소아 환자 검사 등에서 유용할 것으로 생각한다.

Key Factors in Enhancing the Performances of Electrochemically-Assisted Advanced Oxidation Processes

박현웅 한국공업화학회 2011 한국공업화학회 연구논문 초록집 Vol.2011 No.1

Diabetes, Insulin Resistance and Atherosclerosis Surrogates in Patients With Coronary Atherosclerosis

박현웅,권택근,김기영,배장호 대한심장학회 2010 Korean Circulation Journal Vol.40 No.2

Background and Objectives: Undiagnosed diabetes mellitus (DM) or impaired glucose tolerance (IGT) is not uncommon in patients with coronary atherosclerosis and is known to be associated with abnormal scores for atherosclerosis surrogates. We sought to determine the prevalence of undiagnosed DM or IGT, and the association between insulin resistance (IR) and atherosclerosis surrogates in patients with coronary atherosclerosis. Subjects and Methods: The study population consisted of 187 consecutive patients with angiographically proven coronary atherosclerosis (mean: 61 years old, 94 males). We measured carotid intima-media thickness (IMT) and flow mediated brachial artery dilatation (FMD). We also did oral glucose tolerance tests (OGTT), quantitative insulinsensitivity check indexes (QUICKI) and homeostasis model assessment-IR (HOMA-IR). Results: Abnormal OGTT was found in 164 patients (87.7%), even though there were only 63 known cases of DM (33.7%). There were 58 patients (31%) with newly diagnosed IGT and 43 patients (23%) with newly diagnosed DM. There were 71 patients (38%) who had IR (defined as measured HOMA-R ≥3.0). HOMA-IR showed a positive correlation with body mass index (BMI) (r=0.275, p<0.001) and triglycerides (r=0.2, p=0.01), whereas QUICKI had a negative correlation with BMI (r=-0.26, p<0.001), total cholesterol (r=-0.15, p=0.04), triglycerides (r=-0.21,p=0.004) and low-density lipoprotein-cholesterol (LDL-C) (r=-0.17, p=0.02). HOMA-IR and QUICKI were not significantly correlated with IMT or FMD. Conclusion: This study suggests that there is a high incidence of undiagnosed DM and IGT, but atherosclerosis surrogates are not associated with IR in patients with coronary atherosclerosis.

1발표장 : 촉매 및 반응공학1 ; I-12 : Effects of TiO Surface Fluorination on Photocatalytic and Photoelectrochemical Behaviors

박현웅,최원용 한국화학공학회 2007 화학공학의이론과응용 Vol.10 No.1

The formation of surface fluorides on TiO2 (F-TiO2) uniquely affects both photocatalytic reactions and photoelectrochemical behaviors. The fluoride adsorption is favored at acidic pH and greatly reduces the positive charge on TiO2 by replacing ≡Ti-OH by ≡Ti-F species. Effects of surface fluorination on the photocatalytic reactivities are very different depending on the kind of substrates to be degraded. The photocurrents collected in TiO2 suspensions, which are mediated by electron shuttles, and short-circuit photocurrents are also markedly reduced in the presence of F-. It is proposed that fluorination enhances OH radical-mediated oxidation rate and inhibits hole-transfer mediated oxidation rate due to the hindered adsorption (or complexation) of substrates on F-TiO2. In addition, ≡Ti-F group seems to act as an electron-trapping site and to reduce interfacial electron transfer rates by tightly holding trapped electrons due to the strong electronegativity of the fluorine. Finally, elementary charge transfer processes on F-TiO2 and their implications to photocatalytic reaction pathways are discussed.

Ag(I) ions working as a hole-transfer mediator in photoelectrocatalytic water oxidation on WO3 film

박현웅,전태화,최원용 한국공업화학회 2021 한국공업화학회 연구논문 초록집 Vol.2021 No.-

초등교사의 정서표현 양가성이 사회적 상호작용 불안에 미치는 영향: 사회적 지지의 매개효과

박현웅,김춘경 학습자중심교과교육학회 2022 학습자중심교과교육연구 Vol.22 No.17

Objectives The purposes of this study were to examine the effects of elementary school teacher’s emotional expressive ambivalence on social interaction anxiety, focusing on the mediated effects of social support. Methods It was analyzed in regression analysis. Online survey was conducted on 356 elementary school teachers in Daegu and Gyeongsangbukdo. After that, the statistical significance of the mediating effect was verified by applying the SPSS Process Macro No. 4 model. Results The main findings of this study are as follows: First, It was showed as significant correlation among emotional expressive ambivalence, social interaction anxiety, social support. Second, Social support partially mediated the association between self-defensive ambivalence over emotional expressiveness and social interaction anxiety. Third, Social support did not partially mediated the association between relation-involved ambivalence over emotional expressiveness and social interaction anxiety. Conclusions Based on the above results, this study attempted to examine the effects of elementary school teacher’s emotional expressive ambivalence on social interaction anxiety, and to present basic data on programs and counseling interventions that can alleviate it, and to suggest the necessity of continuous research related to elementary school teacher’s anxiety. 목적 본 연구에서는 초등교사의 정서표현 양가성이 사회적 상호작용 불안에 미치는 영향에서 사회적 지지의 매개효과를 탐색함으로써 불안을 완화할 수 있는 방안을 찾고자 하였다. 방법 이를 위하여 대구⋅경북 소재 초등교사 356명을 대상으로 온라인 설문조사를 실시하였다. 자료분석은 Window spss 25.0 을 이용하여 신뢰도 분석 및 기술통계를 실시하였고, 정서표현 양가성이 사회적 지지를 매개하여 사회적 상호작용 불안에 미치는효과가 유의한지를 검증하기 위하여 SPSS Process Macro 4번 모델을 적용하였다. 결과 첫째, 정서표현 양가성과 사회적 상호작용 불안은 정적으로, 사회적 지지와는 부적으로 관련이 있었다. 둘째, 정서표현 양가성하위 요인 중 자기방어적 양가성과 사회적 상호작용 불안의 관계에서 사회적 지지의 부분매개효과가 유의한 것으로 나타났다. 셋째, 정서표현 양가성 하위 요인 중 관계관여적 양가성과 사회적 상호작용 불안의 관계에서 사회적 지지의 부분매개효과는 유의하지 않았다. 결론 이를 토대로 초등교사들이 경험하는 사회적 상호작용 불안에 대해 살펴보고 이를 완화할 수 있는 상담 및 프로그램 개발의 기초자료를 제시하고자 하였으며, 관련된 지속적 연구의 필요성을 시사하고자 하였다.