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삼봉강룡반어탕(三蓬薑龍半魚湯) 가(加) 하고초(夏枯草)와 加(가) 별갑(鱉甲)의 항암효과에 대한 비교연구
박정섭,정승민,임영남,고호연,한지완,김동우,Park, Jung-Sup,Jung, Seung-Min,Yim, Young-Nam,Ko, Ho-Yeun,Han, Ji-Wan,Kim, Dong-Woo 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.4
In this piece of research, Prunellae spica is added to Sambonggangyongbaneotang for one group and Trionycis carapax is added to Sambonggangyongbaneotang for the other group. With these two different prescriptions, the degrees of tumor suppression are compared to develop a better prescription. SKH = Sambonggangyongbaneo-tang + Prunellae Spica SKB = Sambonggangyongbaneo-tang + Trionycis Carapax The results were as follows: 1. SKH and SKB demonstrated anti-tumor effects against tumor advancement of S-180 2. SKH and SKB showed on elevation of macrophage for tumor-bearing mice. 3. $100{\mu}g/ml,\;500{\mu}g/ml$ of SKH and $500{\mu}g/ml$ of SKB demonstrated a rise in alkaline phosphates of B-Lymphocyte in the spleen in tumor-bearing mice. Results support a role for both SKH and SKB for anti-tumor effects via endorsement of macrophage and encouragement of B-lymphocyte toward S-180.
Streptozotocin 유발 당뇨 백서에 상엽 지각(桑葉 枳殼) 혼합물의 항당뇨 및 혈관탄성개선 효과
박정섭,박종형,전찬용,최유경,황귀서,김동우,Park, Jung-Sup,Park, Chong-Hyeong,Jun, Chan-Yong,Choi, You-Kyung,Hwang, Gwi-Seo,Kim, Dong-Woo 대한한방내과학회 2007 大韓韓方內科學會誌 Vol.28 No.3
Objectives : This study was designed to evaluate the anti-diabetes and vasoelasticity effects of Mori Folium and Aurantii Fructus in streptozotocin-induced type II diabetes mellitus model. Methods : The anti-diabetic effect of Mori Folium and Aurantii Fructus on rats induced with diabetes by streptozotocin was investigated through analyses of changes in body weight, blood glucose, urine volume of rats, viability of human umbilical vein endothelial cells(HUVECs), and elasticity of descending thoracic aorta in rats. The subjects in this study were divided into four groups(n=15): a normal group without any treatment (Con), a normal group with Mori Folium and Aurantii Fructus treatment(Con+P), a diabetes group induced by streptozotocin(STZ), and a Mori Folium and Aurantii Fructus treatment group under diabetes induced by streptozotocin(STZ+P). Rats were administered streptozotocin to induce diabetes. Results : The study showed that Mori Folium and Aurantii Fructus significantly reduced highly increased blood glucose levels(p<0.01) and prevented the diabetic rats from weight loss(p<0.01) and polyurea(p<0.05), Mori Folium and Aurantii Fructus also recovered decreased viability of HUVECs(p<0.01) and damaged elasticity of aorta induced by the streptozotocin (p<0.01). Conclusions: It was concluded from the results that Mori Folium and Aurantii Fructus have a distinct anti-diabetes effect and they also prevent damage of blood vessel induced by diabetes. resulting in prevention of cardiovascular diseases ascribed to diabetes.
박정섭,정승민,이시형,정기용,여현수,하유군,최유경,전찬용,김동우,박종형,Park, Jung-sup,Jung, Seung-min,Lee, Si-hyung,Jung, Ki-yong,Yeo, Hyun-soo,Hsia, Yu-chun,Choi, You-kyung,Jun, Chan-yong,Kim, Dong-woo,Park, Chong-hyeong 대한중풍순환신경학회 2006 대한중풍.순환신경학회지 Vol.7 No.1
Objectives : This study was prepared for investigating the clinical features of stroke patients. Methods : We retrospectively reviewed the medical records of 102 patients who were admitted to Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University with a diagnosis of stroke from Jan. 1, 2004 to Dec. 31, 2004. Results : Ischemic stroke(include TIA, 82.4%) was more common than hemorrhagic stroke(17.6%). The incidence in male was 41.2%, in female was 17.6% and the most prevalent age group is over-sixties. Cerebral infarction was most frequently noticed in lacunar-infarction and hemorrhage in putamen. Hypertention, the most preceding diseases, followed by diabetes mellitus and CVA. The rate of recurrence was 27.45%. Cerebral infarction and cerebral hemorrhage was much occurred after rising. The most patients visited the hospital within 24 Hours. The most common symptoms in admission time were motor weakness and speech disorder. The complication was mostly mental disorder. Conclusion : Our study on CVA patients was similar to previous studies from 1994 to 2003. In most cases, western and oriental treatment and medicine were given synthetically.
박정섭,이경진,오은비,김희언,이승엽,최동성,Park, Jeong-Seob,Lee, Kyong-Jin,Oh, Eun-Bi,Kim, Hee-Yeon,Lee, Seung-Yeob,Choi, Dong-Seong 한국식품영양학회 2014 韓國食品營養學會誌 Vol.27 No.5
고구마 경엽을 식품소재로 활용하기 위해 신황미, 하얀미, 스이오우를 수확시기(60, 90, 120일) 및 마디별(1~5, 6~10, 11~15마디)로 채취, 동결건조한 후 분쇄하여 L값과 총 폴리페놀 함량, DPPH 라디칼 소거 활성을 측정하였다. 그 결과, 신황미는 하얀미, 스이오우에 비해 높은 폴리페놀 함량과 DPPH 라디칼 소거 활성을 나타냈으며, 이는 재배기간이 길수록 정상의 순에 가까울수록 높았다. 90일 동안 재배한 후 1~10마디의 경엽을 채취, 2단계 열풍건조법으로 제조한 신황미, 하얀미, 스이오우 경엽 분말의 총 아미노산 함량은 각각 2,469, 3,384, 2,531 mg/100 g, 총 무기물 함량은 각 7.23, 6.54, 7.11 g/100 g, 총당은 각 11.6, 12.8, 18.2 g/100 g, 비타민 E 함량은 3.04, 3.18, 1.52 mg/100 g이었다. 또한 총 폴리페놀 함량은 각각 5.03, 3.90, 4.02 mg/g, ${\beta}$-카로티노이드는 75.6, 71.6, 63.1 mg/g이었고, DPPH 라디칼 소거 활성($EC_{50}$)은 각각 0.29, 0.36, 0.33 mg, ABTS 라디칼 소거 활성($EC_{50}$)은 0.12, 0.15, 0.11 mg으로 시금치보다 2배 이상 강한 활성을 나타내었다. The foliage of sweet potato [Impomoea batatas (L.) Lam] is an excellent source of food material due to the functional components of polyphenol and carotenoid. In this study, the lightness (L-value), polyphenol contents, and DPPH radical scavenging activity of the foliage of Shinwhangmi, Hayanmi and Suioh cultivars harvested after different cultivation periods (60, 90 and 120 days after planting) and according to tip locations (1st~5th, 6th~10th, 11th~15th tips) were investigated. As a result, Shinwhangmi showed a lower lightness value (60 days after planting and 1st~5th tips). The longer the cultivation periods and the closer the tips, the higher the contents of polyphenol and DPPH radical scavenging activity were in lyophilized foliage of Shinwhangmi, Hayanmi and Suioh. In the 1st~10th tip of Shinwhangmi, Hayanmi and Suioh cultivated for 90 days and dried by 2 step hot-air (1st: $70^{\circ}C$ for 8 hr, 2nd: $80^{\circ}C$ for 4 hr), the polyphenol and ${\beta}$-carotenoid contents were 5.0, 3.9 and 4.0 mg/g and 75.6, 71.6 and 63.1 mg/g, respectively. The DPPH radical scavenging activities and ABTS radical scavenging activities ($EC_{50}$) were 0.29, 0.36 and 0.33 mg and 0.12, 0.15 and 0.11 mg, respectively. These antioxidative activities were over two times stronger than spinach.
박정섭,이시형,임영남,정기용,전찬용,박종형,김동우,Park, Jung-Sup,Rhee, See-Hyung,Yim, Young-Nam,Jung, Ki-Young,Jun, Chan-Young,Park, Chong-Hyeong,Kim, Dong-Woo 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.3
Objectives : This study was designed to evaluate the effects of oriental herb medicine therapy on a limited stage small ell lung cancer(SCLS) patient. Methods : The medical record of this case of SCLS was researched. The patient had been treated with oriental herb medicine for five months continuously in OPD. Clinical data was analyzed and the mass of small cell lung cancer before and after oriental herb medicine therapy was compared using X-ray and CT scan of the whole body in order to determine metastasis. Result : After 5 months of oriental herb medical treatment, most of symptoms disappeared or improved. The small cell lung cancer patially receeded and improvements were mainly seen in sputum, coughing, insomnia, diarrhea, and performance status. Conclusion : The study suggests that oriental herb medicine therapy effects the tumor size by causing remission and Improving health and relieving symptoms, and also positively effects the quality of life as a supportive or curative therapy for SCLC patients.
한국물류기업의 몽골진출을 위한 전략적 방안에 관한 연구
박정섭 ( Jung Sub Park ),이재은 ( Jae Eun Lee ) 한국물류학회 2014 물류학회지 Vol.24 No.2
본 연구는 내륙국가인 몽골의 물류현황을 살펴보고 현재 몽골진출을 위해 노력하는 한국기업들의 몽골진출을 위한 전략적인 시사점을 제공하고자 하였다. 연구결과는 다음과 같다. 먼저, 몽골은 풍부한 지하자원의 개발과 수출을 위한 물류인프라의 구축이 절실하다. 둘째, 다각적인 물류망을 위한 노력이 절실히 요구된다. 최근 몽골정부는 광물자원 수송경로의 다변화를 위해 TMGR-TSR/TCR철도노선을 연계개발 추진 중이다. 셋째, 물류인프라는 국가발전의 중요한 요소이며, 국가정책의 일환으로써 수행되어져야 할 것이다. 넷째, 광산자원의 원재료수출에서 제조업화를 통해 부가가치를 창출하고 향상시키는 전략이 요구된다. 포장이사의 선두이자 대중화를 선도한 KGB물류그룹이 최근 몽골법인 KGB MGL을 세우고 다양한 관계형성을 추진하는 것도 좋은 예라 할 수 있다. 따라서 한국과 몽골의 지속적인 관계형성을 위해서는 이에 따른 한·몽 양 정부 간 효율적인 물류정책 방안과 효과적인 물류정책의 시행이 절실히 요구된다. his study aims to identify the logistics of Mongolia, an inland nation, and to give strategic insight for Korean enterprises which are trying to extend their business to Mongolia. Mongolia needs to build logistic infrastructure to develop and export abundant underground resources. They also need to make efforts to build multilateral logistic networks. Recently, the Mongolian government has been working to develop a TMGR-TSR/TCR railway route to diversify the transport routes of mineral resources. The logistic infrastructure is an important element in national development, and systematic implementation is required as a national policy. Strategies are required in order to create and improve the value of exporting raw materials and developing manufacturing. A good example is the KGB logistic group, which leads the packing and moving businesses and which recently established a Mongolian branch, KGB MGL, and which has built diverse relationships. In order to build a stronger relationship between Korea and Mongolia, we need to implement efficient and effective logistic policies between the Korean and Mongolian governments.