http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
미세먼지의 di(2-ethylhexyl) phthalate가 유도한 피부상피세포 사멸 신호전달기전 연구
박정배,김지윤,성정희,김용웅,이세중,Park, Jeong-Bae,Kim, Ji-Yun,Sung, Junghee,Kim, Yong-ung,Lee, Sei-Jung 한국환경과학회 2020 한국환경과학회지 Vol.29 No.3
Particulate matter with an aerodynamic diameter of less than 2.5 μM (PM<sub>2.5</sub>) is one of the major environmental pollutants. Di(2-ethylhexyl) phthalate (DEHP), an endocrine disrupting chemical in PM<sub>2.5</sub>, has been utilized for the manufacturing of polyvinyl chloride to increase the flexibility of final products. In the present study, we investigated the ecotoxicological effect of DEHP on the viability of skin keratinocytes (HaCaT). DEHP induced apoptotic cell death mediated by phosphorylation of extracellular signal-regulated kinase through the production of intracellular Reactive Oxygen Species (ROS). Interestingly, we found that DEHP induces the phosphorylation of the nuclear factor-kappa B responsible for the expression of cleaved caspase-3 as an executional cell death protease in HaCaT cells. On the basis of these results, we suggest that DEHP in PM<sub>2.5</sub> induces the apoptotic death of human keratinocytes via ROS-mediated signaling events.
방사선사진과 임상검사에서 하악 대구치 치근의 형태학적 구조 및 치조골 수준에 관한 비교연구
박정배,정진형,Park, Jung-Bae,Chung, Chin-Hyung 대한치주과학회 2004 Journal of Periodontal & Implant Science Vol.34 No.2
Periodontal defects of the furcation are characterized by several inherent anatomic factors that can make successful periodontal therapy difficult and results unpredictable. The severity and rate of occurrence of periodontal disease are directly related to the location of the furcation relative to the cementa-enamel junction and anatomical form of the root by limiting the accessibility and effectiveness of the periodontal instrumentation. This study investigated the reliability and accuracy of panoramic radiograph diagnoses of the periodontal state of mandibular molars, particularly regarding the diagnosis of furcation area periodontal defects, treatment planning, and prognosis prediction. This study examined a total of 110 teeth belonging to 33 subjects (19 male, 14 female) presenting with incipient to moderate periodontitis 4-7mmpocket depth. The alveolar bone level, length and width of the root trunk, and root separation angle were measured using the panoramic radiograph and compared to the results taken directly by retracting a full-thickness flap. The results of the study are as follows: 1. Data regarding the alveolar bone level of the mandibular first molar showed that the directly taken surgical measurements resulted in $5.1{\pm}0.9mm$ that was slightly deeper than the corresponding panoramic measurement resulted in $4.8{\pm}0.8mm$, but these differences were statistically insignificant (p>0.05). 2. The data of the directly taken surgical measurement of the mandibular second molar $(5.1{\pm}1.1mm)$ was slightly deeper than the corresponding panoramic measurement $(4.7{\pm}1.2mm)$, but these differences were statistically insignificant (p>0.05). 3. The measured values of the length and width of the mandibular first molar root trunks were determined to be $4.1{\pm}0.6mm$ and $7.3{\pm}0.9mm$, respectively, while the values of the mandibular second molar root trunks were determined to be $4.6{\pm}1.3mm$ and $7.6{\pm}0.9mm$ respectively. The differences between these values were found to be statistically significant (p<0.01). 4. The measured values of the root separation angle showed that the mandibular first molars averaged $34.5{\pm}4.4^{\circ}$, while the mandibular second molars averaged $23.0{\pm}10.0^{\circ}$. The differences between these values were found to be statistically significant (p<0.01).
2-플로렌-9-일리덴-말론나이트릴을 기본으로 한 π-공액구조 고분자합성 및 전기-광학적 특성
박정배 ( Jeong Bae Park ),박상준 ( Sang Jun Park ),신웅 ( Woong Shin ),유혜리 ( Hye Ri You ),박성수 ( Sung Soo Park ),김주현 ( Joo Hyun Kim ) 한국화상학회 2009 한국화상학회지 Vol.15 No.4
Heck coupling 반응을 이용해서 poly{2-[2-(2,5-bis-dodecyloxy-4-propenyl-phenyl)-vinyl]-7-methyl-fluoren-9-one(PFone), poly{2-[2-(2,5-bis-dodecyloxy-4-propenyl-phenyl)-vinyl]-7-methyl-fluoren-9-ylidene}-malonitrile(PF2CN)을 합성하였다. 합성한 중합체의 광학적, 전기화학적 특성을 흡수, 형광분 광법 및 cyclic voltammetry(CV)를 통해 확인하였다. PFone과 PF2CN 필름의 흡수 극대치는 410 nm과 410.5 nm에서 나타났다. PFone 및 PF2CN의 최대 발광파장은 각각 633과 635nm로 나타났다. PFone과 PF2CN의 band gap은 각각 2.06eV 과 2.36eV이고 CV를 통해 측정한 LUMO 에너지 준위는-3.36eV 와 -3.46eV로 나타났다. Poly{2-[2-(2,5-bis-dodecyloxy-4-propenyl-phenyl)-vinyl]-7-methyl-fluoren-9-one (PFone) and poly{2-[2-(2,5-bis-dodecyloxy-4-propenyl-phenyl)-vinyl]-7-methyl-fluoren-9-ylidene}-malonitrile (PF2CN) were synthesized by the Heck coupling reaction. Optical and elctrochemical properties of polymers were investigated by the UV-Vis spectrophotometry, fluorometry and cyclic voltammetry. The absorption maximum wavelength of PFone and PF2CN appeared at 410 nm and 410.5 nm, respectively. The photoluminescence maximum wavelength of PFone and PF2CN showed at 633 nm and 635 nm. The band gap energy of PFone and PF2CN figured out from the UV-Vis spectra were 2.06 eV and 2.36 eV, respectively. The LUMO energy level of PFone and PF2CN estimated from the cyclic voltammetry were -3.36eV and -3.46eV, respectively
환경 독성 억제효과를 가진 커큐민 나노스피어가 마우스의 사료 효율 및 악취저감에 미치는 영향
박정배 ( Jeong-bae Park ),이영민 ( Young-min Lee ),박문기 ( Moon-ki Park ),민태선 ( Taesun Min ),이세중 ( Sei-jung Lee ) 한국환경과학회 2019 한국환경과학회지 Vol.28 No.2
Curcumin (C<sub>21</sub>H<sub>20</sub>O<sub>6</sub>) is a hydrophobic polyphenol found in turmeric. Although curcumin has been used as a natural medicine, its major limitation is related to poor absorption from the gut. Therefore, we developed a method for preparation of Curcumin Nanospheres (CN) to improve the aqueous-phase solubility of curcumin and investigate the functional role of CN in promoting feed efficiency and odor reduction in mice. CN showed inhibitory effects on actate dehydrogenase (LDH) cytotoxicity induced by ecotoxic substance toluene in gut epithelial HCT116 cells. In addition, the weights of internal organs (liver, heart, kidneys, and spleen) and the levels of serum Glutamate Oxaloacetate Transaminase (GOT), Glutamate Pyruvate Transaminase (GPT), and LDH did not show significant differences between mice administered oral CN for two weeks and compared to the control group. Interestingly, CN not only reduced hydrogen sulfide (H<sub>2</sub>S) and ammonia (NH<sub>3</sub>) levels and fecal odor, but also improved feed efficiency in mice. These results demonstrate that oral nano-delivery of anti-ecotoxicological CN is a functional system to deliver curcumin to the gut to improve feed efficiency and reduce fecal odor in mice.
박정배(Jeongbae Park),민성기(Seongki Min),이세영(Seyoung Lee),김영신(Youngsin Kim),이종철(Jongchul Lee),장기원(Kiwon Jang) 한국추진공학회 2011 한국추진공학회 학술대회논문집 Vol.2011 No.5
연료탱크 내부에 존재하는 공기는 저장중 연료의 산화를 유발하고, 연료 이송성능을 저하시킬 수 있다. 따라서 항공기 연료탱크의 주유절차를 개선하기 위하여 연료탱크 내부에 존재하는 공기를 줄이는 방안으로 진공주유방식을 제안하였다. 본 논문에서는 진공주유 절차를 수립하여 실제 시험을 수행해 보았고, 이를 통해 진공주유중 발생하는 현상을 관찰할 수 있었다. 또한 탱크 내부의 기포 및 주유시간 절감을 위하여 다른 개선된 방안들을 제안하였다. The air remained in the fuel tank could cause oxidation of fuel during storage, and it also reduce the fuel transfer performance. To find better procedure for refueling of aircraft fuel tank, the vacuum refueling process was proposed to reduce air in the fuel tank. In this study, the vacuum refueling process established and tested, it could be helpful to find out what happened during vacuum refueling. Also the revised vacuum refueling processes were proposed to reduce the remained air and refueling time for aircraft fuel tank.
박정배(Jeong-Bae Park),정성민(Sungmin Jung),이승일(?Seungil Lee),김영신(Young Shin Kim),전필선(Pil Sun Jun) 한국추진공학회 2014 한국추진공학회 학술대회논문집 Vol.2014 No.12
항공기 또는 발사체, 유도무기와 같은 고속비행체의 가압식 연료탱크에는 비행 종단부에서 가속도의 급격한 변화에 따른 연료이송단절 방지와 엔진으로의 기체유입을 차단할 수 있는 특별한 장치가 필요하다. 이러한 측면에서 유체의 표면장력을 이용하여 기체유입을 차단하는 Surface tension screen과 가속도 변화에 영향을 감소시키는 Collector tank가 고안되었다. 본 논문에서는 장치의 성능을 예측하고 영향을 미치는 주요 인자들을 규명한다. 또한 장치에 이용되는 mesh screen의 성능을 예측하고 실험을 통해 결과를 확인 하였다. A special device is required to prevent the disconnection of fuel transfer as rapidly change of acceleration and the inflow of gas to the engine in a pressurized fuel tank. To meet this requirement, the tube using surface tension and Tank for decreasing influence of acceleration was developed. This article predict to the device’s performance and to determine significant factor affecting device’s performance. Analytical study of Mesh screens performance and expreiment of screens performance were conducted.
흡열반응을 적용한 연료공급 및 냉각계통 구성품 시험장치 개발
박정배(Jeongbae Park),이영수(Youngsoo Lee),신동인(Dongin Shin),박수용(Sooyoung Park),최세영(Seyoung Choi) 한국추진공학회 2014 한국추진공학회 학술대회논문집 Vol.2014 No.12
고속비행체의 연료공급 및 냉각계통에 적용되는 연료의 흡열반응을 이용한 냉각 특성을 확인하기 위해 열교환 냉각채널과 이를 시험할 수 있는 시험 장치를 구성하였다. 이를 이용하여 연료의 흡열반응을 일으킬 수 있는 초임계 온도 및 압력 환경을 구현하였다. 시험결과를 토대로 촉매의 연료분해 영향성을 비교 평가함으로써, 흡열 열교환 냉각채널과 촉매의 고속비행체 연료계통 시스템 및 냉각계통에 적용 가능성을 확인하였다. The test system of heat exchanger cooling channel was composed with the aim of researching a fuel cooling characteristic using endothermic reaction on fuel supply and cooling systems of high-speed vehicles. It employed a simulate endothermic reaction caused to the supercritical state of fuel. With this result, Catalyst influenced for fuel cracking was confirmed in comparison to verify applicability of endothermic heat exchanger cooling channel with catalyst to the fuel supply and cooling system of high-speed vehicles.
초,중등정보S/W교육 : 교육 데이터마이닝 기법을 이용한 소셜러닝 학습자들의 학습활동 분석
박정배 ( Jeoung Bae Park ),임희석 ( Heui Seok Lim ) 한국컴퓨터교육학회 2015 한국컴퓨터교육학회 학술발표대회논문집 Vol.19 No.1
본 연구에서는 SNS를 활용한 학습자들간 상호관심도 변화를 통해 학습활동을 활발히 이어가는 그룹과 그렇지 못한 그룹 간의 차이점을 비교분석 하였다. 이를 위해 교사와 학생, 학생들 간의 댓글(Retweet), 좋아요(Like) 등을 상호관심도로 표현 하였으며, 이를 네트워크 모형으로 시각화하였다. SNS를 활용한 학습자들의 경우 Hub 역할을 하는 학습자가 생성되지 못한 그룹은 학습자 간 SNS 활동을 활성화 시키지 못하고 해당 SNS 그룹의 모든 학습자간 상호관심도가 현저히 떨어지는 모습을 관찰 할 수 있었다. 즉, SNS 학습그룹의 경우 여러 학생들 간의 구심점 역할을 하는 Hub 의 역할이 매우 중요하며, 이후에는 Sub Hub 가 나타나는 모습을 관찰 할 수 있었다. SNS를 활용한 학습그룹 중 학습 활동을 꾸준히 유지해 가는 그룹의 경우에는 Hub 와 학습자들, 학습자들간 연결고리 역할을 하는 Sub Hub 의 역할이 중요한 것으로 나타났다.