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박재후,임호영,김효철,박광화,곽연식 아주대학교 의과학연구소 1996 아주의학 Vol.1 No.1
Allogeneic bone marrow transplantation(BMT) using HLA-idenstical siblings were carried out in 4 patients with severe aplastic anemia from 1990 to 1995. Patients were conditioned with cyclophosphamide and total lymphoid irradiation(TLI) or cyclophosphamide, antilymphocyle globulin(ALG) and procarbazine, which provided successful engraftment. In order to prevent mismatched transfusion reaction hemagglutinins in the recipient was removed by plasmapheresis and depletion of erythiocytes from donor marrow could be easily separated using starch sedimentation method. The engraftment was evident with the increase of the peripheral blood counts and increased cellularity in bone marrow biopsies at the fourth week. In 2 cases, mild(Grade Ⅰ) acute graft-versus-host disease(aGVHD) was developed, but the patients were recovered spontaneously. All of the recipients are now in complete hematologic recovery and in good health more than 48 months, 5 months and 2 months respectively.
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Cement Leakage into Adjacent Vertebral Body Following Percutaneous Vertebroplasty
박재후,김현성,김석원 대한척추신경외과학회 2016 Neurospine Vol.13 No.2
Percutaneous vertebroplasty (PV) is a minimally invasive procedure for osteoporotic vertebral compression fractures that fail to respond to conventional conservative treatment. It significantly improves intolerable back pain within hours, and has a low complication rate. Although rare, PV is not free of complications, most of which are directly related to cement leakage. Because of its association with new adjacent fracture, the importance of cement leakage into the adjacent disc space is paramount. Here, we report an interesting case of cement leakage into the adjacent upper vertebral body as well as disc space following PV. To the best of our knowledge, there has been no report of cement leakage into the adjacent vertebral body following PV. This rare case is presented along with a review of the literature.
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박재후 고신대학교(의대) 고신대학교 의과대학 학술지 1990 고신대학교 의과대학 학술지 Vol.6 No.1
Allogenic bone marrow transplantation was camed out 23-year-old male with severe aplastic anemia from HLA identifcal sibling. Patient was conditioned with cyelophosphamide and fractionated total lymphoid irradiation. The engraftment was identified with the increase of the peripheral blood cell counts and with the finding of bone marrow at Day+17 and discharged at Day+34. Acute graft-versus-host disease(GVHD) was not developed. He is now in complete hematologic recovery and in good health more than 3 months, but is now under control with cyclosporin and trimethoprim-sulfamethoxazole.
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