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시험관 아기 시술에서 여성의 연령이 수정란의 질과 다태 임신 발생에 미치는 영향
이명섭,박장옥,정지학,박준숙,강희규,김동훈,이호준,Lee, Myeong-Seop,Park, Jang-Ok,Jung, Ji-Hak,Park, Jun-Suk,Kang, Hee-Gyoo,Kim, Dong-Hoon,Lee, Ho-Joon 대한생식의학회 2000 Clinical and Experimental Reproductive Medicine Vol.27 No.3
Objective: This study was performed to evaluate the influence of maternal age on embryo quality and the frequency of multiple pregnancy in IVF-ET program. Method: 86 conventional IVF-ET cycles were divided into three groups according to the age by 5 year (group A: 26-30, group B: 31-35, group C: 36-40 yrs). The in vitro fertilization and development outcome (fertilization, cleavage and high quality embryo rate) and the pregnancy outcome (pregnancy, implantation, G-sac/high quality embryo and multiple pregnancy rate) were examined. And then, these results were compared among the groups. Results: The rates of fertilization (62.7, 68.5 and 65.4%, respectively) and cleavage (95.6, 97.6 and 98.0%, respectively) were not different among the groups. And the high quality embryo (HQE) rate also was not different among the groups (61.8, 62.9 and 62.8%, respectively). The pregnancy rate of group C (23.3%) was significantly lower than that of group A (41.2%) and B (48.7%). And the implantation rate was significantly decreased with advance in maternal age (group A; 17.3%, B; 12.6% and C; 6.0%). The G-sac/high quality embryo rate was significantly higher in group A (70.8%) when compared to group B (32.2%) and C (40.0%). On the other hand, the multiple pregnancy rate was significantly lower in group C (14.3%) when compared to group A (71.4%) and B (36.8%). Conclusion: The pregnancy rate was significantly decreased over 35 years. The G-sac/HQE and multiple pregnancy rate were significantly high below 31 years. Thus, these results suggest that the number of high quality embryo transferred should be limited by the age and another criteria for embryo quality evaluation were required for single embryo transfer.
X형 감쇠시스템을 위한 복원성 점성 감쇠기 성능 실험 및 수치모형 개발
김다위 ( Da Vid Kim ),박장호 ( Jang Ho Park ),옥승용 ( Seung Yong Ok ),박원석 ( Won Suk Park ) 한국안전학회(구 한국산업안전학회) 2016 한국안전학회지 Vol.31 No.6
In this study, a restoring viscous damper is introduced for X-type damper system which is designed for the seismic response control of large spatial structures. A nonlinear numerical model for its behavior is developed using the result of dynamic loading tests. The X-type damper system is composed of restoring viscous dampers and connecting devices such as adjustable wire bracing, where the damping capacity of the system is controllable by changing the number of the dampers. The restoring viscous damper is devised to exert main damping force in tension direction, which is effective to prevent the buckling of bracing subjected to compressive axial force. To evaluate the performance of the proposed damper, dynamic cyclic loading tests are performed by using manufactured dampers at full scale. In order to construct the numerical model of the damper system, its model parameters are first identified using a nonlinear curve fitting method with the test data. The numerical simulations are then performed to validate the accuracy of the numerical model in comparison with the experimental test results. It is expected that the proposed system is effectively applicable to various building structures for seismic performance enhancement.