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      • KCI등재

        중증도에 따른 아벨리노 각막이상증의 공초점주사현미경 소견

        박영민,김호윤,이종수,Young Min Park,MD,Ho Yun Kim,MD,Jong Soo Lee,MD,PhD 대한안과학회 2014 대한안과학회지 Vol.55 No.3

        Purpose: In this study we analyzed and objectified the characteristics of the Avellino corneal dystrophy patients considering disease severity using in vivo confocal microscopy (IVCM). Methods: Each corneal layer of 36 eyes in 18 patients with Avellino corneal dystrophy was examined using IVCM (ConfoScan 4.0, NIDEK, Co. Ltd., Albignasego, Italy). Patients were classified into 3 groups based on disease severity (mild, moderate, or severe). Results: In the mild group, hyper-reflective granular deposits without dark shadows were observed in the anterior stroma. As the disease progressed, corneal deposits were also found at the posterior stroma and epithelium, and clusters of hyper-reflective corneal deposits resembling stromal opacity were noted. The range of corneal deposits measured using Z-scan optical pachymeter was 111.14 ± 30.95 um in the mild group, 157.47 ± 25.00 um in the moderate group, and 193.42 ± 52.23 um in the severe group (p < 0.05). Conclusions: The origin of the corneal deposits in Avellino corneal dystrophy may be related to corneal stromal cells and distributed from the corneal epithelial layer to the stromal layer. IVCM might be useful for the standardization of disease severity by digitalizing the range of deposits. J Korean Ophthalmol Soc 2014;55(3):361-367

      • KCI등재

        공초점주사현미경에 의한 푹스각막이상증의 각막조직소견

        박영민,최범석,이종수.Young Min Park. MD. Beom Seok Choi. MD. Jong Soo Lee. MD. PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.9

        Purpose: To analyze the morphology and density of corneal tissue in patients with early stage Fuchs’ corneal endothelial dystrophy (FCED) by in vivo confocal microscopy (IVCM). Case summary: Each layer of the cornea in 2 patients with early-stage FCED was examined with IVCM (ConfoScan 4.0, NIDEK, Co. Ltd., albignasego, Italy). Cross-sectioned corneal images of the corneal epithelium, Bowman’s layer, stromal layer, Descemet’s membrane, and endothelium were evaluated. Corneal epithelium, Bowman’s layer, and anterior stroma of both patients showed no abnormalities. Case 1 was diagnosed as Stage 1 FCED, demonstrating typical changes including pleomorphism, polymegathism, and the presence of guttae in the corneal endothelial layer. Case 2 was diagnosed as Stage 2 FCED, showing several hyper-reflective whitish dots in the posterior stroma, hypo-reflective vertical strands in the stroma adjacent to Descemet’s membrane, and pleomorphism, polymegathism, and guttae in the corneal endothelial layer. Conclusions: IVCM is a non-invasive and effective tool to diagnose early-stage FCED.

      • 2차원 고양력장치의 플랩 형상 및 위치 최적화

        박영민,강형민,정진덕,이해창,Park, Youngmin,Kang, Hyoungmin,Chung, Jindeog,Lee, Hae-Chang 항공우주시스템공학회 2013 항공우주시스템공학회지 Vol.7 No.3

        Numerical optimization of two dimensional high lift configuration was performed with flow solver and optimization method based on RSM(Response Surface Model). Navier-Stokes solver with Spalart-Allmaras turbulence model was selected for the simulation of highly complex and separated flows on the flap. For the simultaneous optimization of both flap shape and setting (gap/overlap), 10 design variables (eight variables for flap shape variation and two variables for flap setting) were chosen. In order to generate the response surface model, 128 experimental points were selected for 10 design variables. The objective function considering maximum lift coefficient, lift to drag ratio and lift coefficient at specific angle of attack was selected to reduce flow separation on the flap surface. The present method was applied to two dimensional fowler flap in landing configuration. After applying the present method, it was shown that the optimized high lift configuration had less flow separation on the flap surface and lift to drag ratio was suppressed over entire angle of attack range.

      • KCI등재

        청폐사간탕(淸肺瀉肝湯)이 급성기 중풍환자의 동맥경직도 및 맥압에 미치는 영향

        박영민,홍진우,신원준,정동원,김석민,배형섭,김영석,문상관,정우상,조기호,Park, Young-Min,Hong, Jin-Woo,Shin, Won-Jun,Jeong, Dong-Won,Kim, Seok-Min,Bae, Hyung-Sup,Kim, Young-Suk,Moon, Sang-Kwan,Jung, Woo-Sang,Cho, Ki-Hoo 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.2

        Objectives : Arterial stiffness and pulse pressure are related to cardiovascular and cerebrovascular survival and longevity. This study is aimed at examining the effects of Chungpyesagan-tang on arterial stiffness and Pulse pressure in acute stroke Patients. Methods: The subject of this study was acute strike Patients within 1 week after ictus, with Cardio-ankle vascular index(CAVI) higher than 9.0. They were divided into two groups: A treatment group (n=44) and a control group(n=46). For two weeks, Chungpyesagan-tang was given to the former, other herbal medicines to the latter. used for stroke patients for the control group for 2 weeks. At the end of first and second week, CAVI, pulse Pressure, National Institute of Health stroke scale(NIHSS), Modified Barthel Index(MBI) were measured. Serum lipid Profile, aspartate transaminase(AST), alanine transaminase(ALT). blood urea nitrogen(BUN), creatinine were also measured at the end of the study. Results : After 2 weeks, CAVI and Pulse Pressure in Chungpyesagan-tane group were significantly tower than those in the control group(P<0.05). NIHSS and MBI were improved in both groups. But there was no significant difference between the treatment group and the control group in terms of the NIHSS and MBI. Conclusions : We suggest Chungpyesagan-tanghas desirable effects on arterial stiffness and Pulse Pressure of acute stroke patients. It can improve morbidity and mortality of patients on the basis of influencing vascular stiffness and increased pulse pressure.

      • KCI등재

        실리콘관 삽입술에서 관의 고정을 위한 실리콘 시트와 봉합사 사용의 임상적 효과 비교

        박영민,구기홍,이지은,이종수,김윤경,Young Min Park,Gi Hong Koo,Ji-Eun Lee,Jong Soo Lee,Yoon Kyung Kim 대한안과학회 2009 대한안과학회지 Vol.50 No.2

        Purpose: To compare the clinical outcome of silicone tube intubation according to the tie methods. Methods: Eighty-eight eyes of 87 patients who underwent silicone tube intubation were divided into two groups based on the tie method: a silicone silastic sheet group (Group 1, n=59) and a nylon 6-0 suture knot group (Group 2, n=29). The two groups were compared according to their success rates, recurrence rates and complications. Results: No significant difference was found in the success rate between the two groups (83.0% in Group 1 and 82.7% in Group 2). However, Group 2 showed a significantly higher rate of postoperative complications than Group 1. In Group 1, 5/59 (8.4%) eyes had ocular irritation, 2/59 (3.4%) eyes exhibited tube prolapse, conjunctivitis, corneal erosion, and dacryocystitis and 1/69 (1.6%) eyes had a punctal slit after intubation. In Group 2, 3/29 (10.3%) eyes had ocular irritation, 2/29 (6.9%) eyes exhibited tube prolapse, conjunctivitis, a punctal slit, and dacryocystitis, and 1/29 (3.4%) eyes showed corneal erosion, or a granuloma after intubation. A recurrence of symptomatic tearing was found in 6/59 (10%) eyes in Group 1 and 3/29 (10%) in Group 2. Conclusions: In silicone tube intubation of incomplete NLD obstruction, the usage of silicone silastic sheets to tie both ends of the silicone tube produced a lower complication rate and a higher success rate than that of the suture knot group. Lower tension on the nasolacrimal passage in the silicone silastic sheet group allows for a significantly lower rate of punctal slit development. Therefore, the method of using silicone silasitic sheets can be considered useful in the treatment of NLD obstruction.

      • KCI등재

        동영상에서 물체의 추출과 배경영역의 상대적인 깊이 추정

        박영민,장주석,Park Young-Min,Chang Chu-Seok 한국정보처리학회 2005 정보처리학회논문지B Vol.12 No.3

        컴퓨터 비젼에 관한 고전적인 연구 주제들 중의 하나는 두 개 이상의 이미지로부터 3차원 형상을 재구성하는 3차원 변환에 관한 것이다. 본 논문은 단안 카메라로 촬영한 일반적인 2차원 영상물에서 능동적으로 움직이는 3차원 영상의 깊이 정보를 추출하는 문제를 다룬다. 연속하는 프레임들간의 영상 블록의 움직임을 평가하여 카메라의 회전과 배율효과를 보상하고 다음과 같은 두 개의 단계에 걸쳐 블록의 움직임을 추출한다. (i) 블록의 위치와 움직임을 이용하여 카메라의 이동과 초점거리에 대한 전역 파라메타를 계산한다. (ii) 전역 파라메타, 블록의 위치와 움직임을 이용하여 평균 영상 깊이에 대한 상대적인 블록의 깊이를 계산한다. 다양한 동영상을 대상으로 특이점인 경우와 그렇지 않은 경우를 실험하였다. 결과로 얻어지는 상대적인 깊이 정보와 객체는 인간이 판단하는 경우와 동일함을 보였다. One of the classic research problems in computer vision is that of stereo, i.e., the reconstruction of three dimensional shape from two or more images. This paper deals with the problem of extracting depth information of non-rigid dynamic 3D scenes from general 2D video sequences taken by monocular camera, such as movies, documentaries, and dramas. Depth of the blocks are extracted from the resultant block motions throughout following two steps: (i) calculation of global parameters concerned with camera translations and focal length using the locations of blocks and their motions, (ii) calculation of each block depth relative to average image depth using the global parameters and the location of the block and its motion, Both singular and non-singular cases are experimented with various video sequences. The resultant relative depths and ego-motion object shapes are virtually identical to human vision.

      • KCI등재

        컬러패턴분류를 위한 히스토그램 매칭기법

        박영민,윤영우,Park, Young-Min,Yoon, Young-Woo 한국정보처리학회 2006 정보처리학회논문지B Vol.13 No.7

        Pattern recognition is the study of how machines can observe the environment, learn to distinguish patterns of interest from their background, and make sound and reasonable decisions about the categories of the patterns. Color image consists of various color patterns. And most pattern recognition methods use the information of color which has been trained and extract the feature of the color. This thesis extracts adaptively specific color feature from images with several limited colors. Because the number of the color patterns is limited, the distribution of the color in the image is similar. But, when there are some noises and distortions in the image, its distribution can be various. Therefore we cannot extract specific color regions in the standard image that is well expressed in special color patterns to extract, and special color regions of the image to test. We suggest new method to reduce the error of recognition by extracting the specific color feature adaptively for images with the low distortion, and six test images with some degree of noises and distortion. We consequently found that proposed method shouws more accurate results than those of statistical pattern recognition. 패턴인식은 주위 환경을 관찰하는 방법, 배경으로부터 관심있는 패턴을 구분하는 방법, 소리를 얻는 방법, 그리고 패턴 범주들 중에서 타당한 결정을 얻는 방법에 관한 연구이다. 패턴인식 시스템을 설계할 때 필수적으로 1) 데이터의 획득과 전처리, 2) 데이터의 표현, 3) 결정방법 선택과 같은 세 가지 사항을 고려해야한다. 그 이유는 영상을 획득하기 위한 센서의 선택, 전처리 기법, 표현 기법, 의사결정 모델에 따라 인식의 결과가 달라질 수 있기 때문이다. 컬러영상은 다양한 컬러 패턴으로 구성된다. 대부분의 패턴인식 방법은 훈련되어진 컬러정보를 사용하여 컬러의 특징을 추출한다. 본 논문은 몇 가지 제한된 컬러를 가진 영상으로부터 특정한 컬러 패턴을 적응적으로 추출한다. 컬러 패턴의 수가 한정되어 있기 때문에 영상에서 컬러의 분포가 유사하다. 그러나, 영상에 잡음이나 열화가 존재하면, 그 분포가 변화한다. 그러므로 이미 알고 있는 컬러정보를 가지고 특정한 컬러의 특징을 추출할 수 없다. 그래서 본 논문에서는 유사한 컬러 패턴을 가진 영상에 대하여 특정한 컬러의 특징을 적응적으로 추출함으로서 인식의 오류를 감소시킬 수 있는 새로운 방법을 제안한다. 제안한 방법을 실험하기 위하여 열화가 적은 표본영상을 사용하고, 잡음과 열화가 포함된 여섯 가지의 검사영상을 사용한다. 결론적으로 제안한 방법이 통계적인 패턴인식의 결과보다 정확한 결과를 보여준다.

      • KCI등재

        주요우울증 환자에서 일주기 형태에 따른 양극성 경향, 자살 사고, 청각유발전위와의 관련성 : 예비 연구

        박영민,이승환,Park, Young-Min,Lee, Seung-Hwan 대한생물정신의학회 2014 생물정신의학 Vol.21 No.1

        Objectives The current study investigated the putative relationship between chronotype and suicidality or bipolarity in patients with major depressive disorder (MDD). Method Nineteen outpatients who met the criteria for MDD according to the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders-text revision were recruited for the current study. The subjects were divided into two subgroups based on their Basic Language Morningness (BALM) scores (dichotomized according to the median BALM score). The Loudness Dependence of Auditory Evoked Potentials (LDAEP) was evaluated by measuring the auditory event-related potentials before beginning medication with serotonergic agents. In addition, K-Mood Disorder Questionaire (K-MDQ), Beck Scale for Suicidal Ideation (BSS), Beck Hopelessness Scale (BHS), Barratt Impulsiveness Scale (BIS) were applied. Results The K-MDQ, BSS, BHS, BIS score was higher for the eveningness group than for the morningness group. However, the LDAEP, Hamilton Depression Rating Scale, Hamilton Anxiety Scale scores did not differ significantly between them. There were negative correlations between the total BALM score and the total K-MDQ, BSS, and BHS scores (r=-0.64 and p=0.0033, r=-0.61 and p=0.0055, and r=-0.72 and p=0.00056, respectively). Conclusions Depressed patients with eveningness are more vulnerable to the suicidality than those with morningness. Eveningness is also associated with bipolarity.

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