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노화된 흰쥐 소장 장신경계의 형태계측학적 변화 및 미세구조 변화에 관한 연구
박승화(Seung Hwa Park),조익현(Ik Hyun Cho),이종은(Jong Eun Lee),이원택(Won Taek Lee),박경아(Kyung Ah Park) 대한해부학회 2001 Anatomy & Cell Biology Vol.34 No.2
노화에 따른 장신경계의 변화를 살펴보기 위하여 3개월 된 Sprague-Dawley계 성숙흰쥐 (300~350 gm)와 24개월 된 노 화흰쥐 (500~550 gm) 소장의 근육층신경얼기와 점막밑신경얼기를 NADH-TR 염색을 하여 형태계측학적 조사를 하였다. 신경세포 형태에 따른 변화를 살펴보기 위하여 각 신경얼기에 존재하는 신경세포를 세가지 유형으로 분류하였다. 세포의 모양이 둥글고 크며 세포질이 핵에 비해 많은 세포를 1형, 세포의 모양이 방추형인 세포를 2형, 세포의 모양이 둥글고 작으며 세포질의 양이 매우 적어 핵이 세포체의 대부분을 차지하는 세포를 3형으로 분류하여 계수하였다. 신경세포의 수와 면적은 VIDAS 영상분석기 (Carl Zeiss, Co., Ltd.)를 이용하여 계측하였다. 또한 노화흰쥐의 장신경계 미세구조의 변화를 JEM-1200 EXII (JEOL Co., Ltd.) 전자현미경으로 관찰하여 다음과 같은 결과를 얻었다. 1. 성숙흰쥐의 근육층신경얼기와 점막밑신경얼기에서 내재성신경인 3형 신경세포가 주를 이루고 있었으며 신경분포밀 도(단위면적당 신경세포의 총수)는 근육층신경얼기에서 보다 점막밑신경얼기에서 더 높았다. 2. 노화흰쥐에서 주로 1형과 2형 신경세포가 소실되었으며 이러한 경향은 두 신경얼기에서 동일하였다. 3. 노화흰쥐에서 신경세포의 면적은 모든 유형의 신경세포에서 증가하였으며 면적변화 양상도 두 신경얼기에서 동일하 였다. 4. 노화흰쥐의 장신경세포에서 관찰한 미세구조의 변화로는 세포질 내에 리포푸신과립의 증가가 가장 두드러졌으며 다 른 세포소기관의 변성현상은 나타나지 않았다. 이상의 결과로 노화로 인한 장신경계에서의 신경세포의 소실은 주로 자율신경에서 기원한 1형과 2형 신경세포에서 일어남을 알 수 있었다. 또한 장신경세포는 노화에 따라 세포질 내에 리포푸신과립이 증가할 뿐 다른 세포소기관은 변성을 나타내지 않음을 알 수 있었다. This study was performed to investigate the morphometric and ultrastructural change in the adult and aged rat small intestine. The myenteric and submucous plexuses were stained by NADH-TR in the ileum of adult Sprague-Dawley rats (3 mo., 300~350 gm) and aged rats (24 mo., 500~550 gm). The neurons of myenteric and sumucous plexuses were divided into 3 groups depending on their cell body morphology. Type 1 cells were polygonal or round with abundant cytoplasm. Type 2 cells were spindle shaped and type 3 cells were small and round with scanty cytoplasm. The nerve cell numbers and sizes were measured using an image analyzer (VIDAS, Carl Zeiss, Co., Ltd.). Ultrastructural changes were observed by JEM-1200 EXII (JEOL Co., Ltd.) electron microscope. The result obtained are as followed: 1. In adult rats, majority of neuron population were type 3 and neuron density (total numbers/1 μm2) was more higher in submucous plexus than in the myenteric plexus. 2. Statistically significant loss of type 1 and type 2 neurons were in myenteric and submucous plexus of aged rat small intestine. 3. All types of neuron sizes were increased in aged myenteric and submucous plexuses. 4. Lipofusin granules were prominent in the cytoplasm of aged rat. Cell organelles were not shown degenerative change. These results suggest that type 1 and type 2 nerve cells which is originated from autonomic nerves were lost in aged rat small intestine. Ultrastructurally lipofusin granules were prominent in the cytoplasm of aged rat and the cell organelles were not degenerated.
신재생에너지의 에너지 하베스팅을 위한 DPP시스템의 구성과 효율계산
박승화(Seung-Hwa Park),이현재(Hyun-Jae Lee),손진근(Jin-Geun Shon) 대한전기학회 2018 전기학회논문지 P Vol.67 No.3
Energy harvesting technology is drawing attention as a means of collecting various eco-friendly energy and accumulating residual energy. Recently, differential power processing (DPP) is being developed as part of energy harvesting. This is being studied as a solution to the loss of power generation between power modules and the problems caused by module small losses depending on the size of power production. In this paper, we propose the necessity of the DPP by comparing and analyzing energy harvesting related module integration system and power supply efficiency of DPP. The power efficiency of the converter and the power difference between the wind power and the photovoltaic power supply have been changed to demonstrate the effectiveness of the proposed system.
실시설계단계에서 수량산출을 위한 복합벽체 자동분할에 관한 연구
박승화(Seunghwa Park),김흥수(Heungsoo Kim),윤두영(Dooyung Yoon) (사)한국CDE학회 2015 한국CDE학회 논문집 Vol.20 No.2
When Building Information Modeling (BIM) was introduced at the early stage, it was only utilized as a three-dimensional visualization tool. Nowadays, however, BIM is being studied for increasing design productivity and managing enormous information on building life cycle. One of the representative research is developing ‘common prototype BIM libraries’. BIM data made of common prototype libraries should be utilized in various ways, quantity takeoff, code checking, energy analysis and so on. However, common prototype BIM libraries are not enough to estimate accurate cost. For example, composite wall libraries should be divided into several single objects, wall structure and finishes, for the quantity takeoff and construction cost calculation. In this paper, we are suggesting an automated division algorithm of composite wall and developing a system prototype for it. This study is expected to reduce extra modeling work and contribute to fast and accurate cost calculation in the construction.
건축부재 형상정보 교환을 위한 개방형BIM 기반의 매핑 시스템 개발
박승화(Seunghwa Park),김인한(Inhan Kim),이지아(Jiah Lee) (사)한국CDE학회 2014 한국CDE학회 논문집 Vol.19 No.2
Parametric modeling is one of BIM’s characteristics and BIM have being utilized for constructability analysis, energy efficiency analysis, and so on in diverse construction field. However, parametric information"s interoperation is not solved until now because different BIM tools have specific algorithm and methods to generate geometric information. To solve the problem, previous research suggested IFC-XML methodology. In this paper, authors studied connections between IFC-XML structure and script-based modeling commends to make libraries in commercial BIM tools such as ArchiCAD<SUP>TM</SUP> and Digital Project<SUP>TM</SUP>. In addition, they made commends mapping tables to exchange geometry information of architectural components. Moreover, mapping system was developed to certify the mapping tables which is classified modeling commends. Finally, translated architectural component model was confirmed using exchanged geometry information in browser.