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폐쇄성 무정자증의 원인 및 정관부고환문합술을 이용한 수술적 교정 가능성
박세환,서주태,조대기,이중식 대한남성과학회 2011 The World Journal of Men's Health Vol.29 No.2
Purpose: To define the causes of obstructive azoospermia (OA) and evaluate the possibility and efficacy of microsurgical correction. Materials and Methods: Sixty-seven patients diagnosed as OA with normal spermatogenesis preoperatively and initially planned to microsurgical vasoepididymostomy from December 2003 and November 2009 were retrospectively analyzed. Causes of OA were analyzed and patency rate and pregnancy outcomes of their female partners were measured. Results: Thirty-one patients (46.3%) could not correct their OA because of obstruction of the distal vas deferens, epididymal atrophy and/or hypotrophy and vasal injury due to previous surgery. Among the 36 patients undergone microsurgical vasoepididymostomy (mean age of patients and their female partners were 32.9 and 31.3 years, respectively), 32 patients (88.9%) were corrected bilaterally and 4 patients (11.1%) unilaterally. The overall patency rate was 17 patients (47.2%); being 15 and 2 patients for bilateral and unilateral procedure, respectively. Among the 17 patients regained the patency after surgery, except 3 cases without followed up, 6 cases achieved natural pregnancy and also 6 cases achieved the pregnancy using the assisted reproduction. Conclusions: According to the affected point of reproductive tract, not all men with obstructive azoospermia were candidates for microsurgical reconstruction. However, reasonable outcomes were achieved in the microsurgical reconstruction cases and it should be primary therapeutic method in obstructive azoospermia. For those in whom reconstruction is not a viable option, surgical methods for sperm retrieval are available to have their own biological children.
박세환,정종은,김용균,강상묵 대한방사선방어학회 2005 방사선방어학회지 Vol.30 No.1
- 한국원자력연구소의 방사선 검출기 연구팀에서는 가스 전자 증폭기를 이용하여 고효율 중성자 검출기를 개발하고 있다. 이중 가스 전자 증폭기를 제작하였고 Ar/Isobutane 혼합기체에서 동작시켰다. 고효율 중성자 검출기에 적용하기 위해서 다중 가스 전자 증폭기 포일 양면에 중성자 변환 물질인 6Li 또는 10B를 코팅하는 것이 고려되었다. 중성자 검출을 위한 박막의 최적화된 두께를 MCNP와 SRIM으로 계산하였다. 중성자 검출 효율은 박막을 구성하는 화합물과 박막 두께를 변화시키면서 계산하였다. 열중성자는 drift plate에 중성자 반응 박막을 입힌 GEM 검출기에 의해서 측정되었다.