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박찬진 ( Chan Jin Park ),김대한 ( Dae Han Kim ),한상호 ( Sang Ho Han ),계명찬 ( Myung Chan Gye ) 한국환경생물학회 2014 환경생물 : 환경생물학회지 Vol.32 No.4
알루미늄은 폐광산 침출수, 산업폐수, 생활하수 등을통해 수계로 유입되어 수생생물에 농축되고 독성을 유발할 수 있다. 최근 다양한 수생생물에서 알루미늄의 독성에 관한 보고가 증가하고 있지만 오염현황 및 생태독성에 대한 연구가 많이 이뤄지지 않았다. 본 소고에서는 수서무척추동물, 어류, 양서류에서 알루미늄의 독성자료를 고찰함으로써 잔류량 가이드라인 설정의 필요성과 알루미늄의 수생태독성 분석전략을 제언하고자 하였다. 다양한 형태의 알루미늄화합물이 수생동물에서 1차적으로 아가미기능을 방해하여 생존을 위협하고 세포독성,유전독성, 산화적스트레스, 내분비계교란, 생식교란, 대사교란, 항상성교란 등의 독성효과가 있는 것으로 확인되었다. 특히, 산성조건에서 환경잔류농도 수준의 알루미늄화합물은 어류에서 호르몬농도 변화를 유발하였다. 알루미늄은 산성 및 염기성 조건에서 용해도가 증가하기 때문에 국내의 폐광산 인근의 산성 수계 뿐 아니라 조류대발생에 의해 pH가 상승하는 호수나 강에서도 알루미늄의 독성효과가 나타날 것으로 사료된다. Aluminum flows into the river from the abandoned mine leachate, industrial wastewater, and sewage and is responsible for acute toxicity in aquatic organisms. Recently, the number of reports have indicated the increased toxicity in a variety of aquatic organisms’ due to the aluminum toxicity. In this study, we reviewed the toxicity of aluminum on aquatic invertebrates, fishes and amphibians and suggested the guideline for management of aluminum residues in aquatic environment and strategies for aluminum toxicity evaluation. In aquatic animals aluminum complexes evoke gill dysfunction primarily, the cytotoxicity, genotoxicity, oxidative stress, disruption of endocrine function, reproductive success, metabolism and homeostasis. Notably, at environmentally relevant concentration, aluminum complex can alter the hormone levels in fish in acidic condition. Further, since the solubility of aluminum is higher in the acidic and basic conditions, thus it is likely that the toxic effects of aluminum may not only occur in acidic water near the abandoned mines but also in lakes and rivers, where pH is raised by algal bloom.
FIR과 FGR 기법이 적용된 메탄-공기 대향류 확산화염에서 화염구조와 NO 배출 연구
박정(Jeong Park),권오붕(Oh Boong Kwon),김세원(Sewon Kim),이창엽(Changyeop Lee),길상인(Sang-In Keel),윤진한(Jin-Han Yun),임인권(In Gweon Lim) 한국연소학회 2016 한국연소학회지 Vol.21 No.1
Flame characteristics and NO emission behavior in CH4/air-air premixed counterflow flames with applying FIR and FGR with CO₂ and H₂O were investigated numerically by varying the ratios of FIR and FGR as well as global strain rate. Chemical effects of added CO₂ and H₂O via FIR and FGR were analyzed through comparing flame characteristics and NO behaviors from real species(CO₂ and H₂O) with those from their artificial species(XCO₂ and XH₂O) which have the same thermochemical, radiative, and transport properties to those for the real species. The results showed that flame temperature and NO emission with FIR varied much more sensitively than that with FGR. Those varied little irrespective of adding CO₂, H₂O, and their artificial species to the fuel stream via FIR. However, Those were varied complicatedly by chemical effects of added CO₂ and H₂O via FGR. Detailed analyses for them were made and discussed.
박성한,장종욱,Park Sung-Han,Jang Jong-Wook 한국정보통신학회 2006 한국정보통신학회논문지 Vol.10 No.2
STP는 토폴로지 구성방법에 따라 네트워크의 성능이 달라진다. 따라서 효율적인 네트워크 환경을 위하여 최적의 토폴로지를 구성할 필요가 있다. 본 논문은 이더넷에서 스위치들 사이의 효율적인 네트워크 구축을 위한 최적의 토폴로지 구성방법을 제안하였다. 루트스위치에서 송신한 프레임을 같은 도메인 안에 있는 스위치들이 프레임을 수신하는 시간을 수학적 모델로 계산하여 최적의 토폴로지 구성 방법을 도출하였다. 그리고 최적의 토폴로지에서의 루트 스위치의 위치에 따른 성능을 분석하였다. 성능 분석 결과 정방형으로 설계된 망에서 루트스위치가 중앙에 위치하게 설계하는 것이 효과적이라는 결론을 얻을 수 있었다. In STP, network performance differs depending on topology configuration. Therefore, we need to configure right topology for the optimal efficiency of networking. This paper suggest the optimal topology configuration for efficient networking between ethernet switchs. It finds out the best topology configuration by calculation mathematical model which uses transmission time between root switch and other switchs in the same domain. And it also analysed performance difference on locations of root switch. Through the performance analysis, we could conclude that placing the root switch in the center is the most efficient.
대시호탕가미방(大柴胡湯加味方)이 고혈압(高血壓) 및 고지혈증(高脂血症)에 미치는 영향(影響)
박치상,박창국,한승동,박순달,Park, Chi-Sang,Park, Chang-Gook,Han, Seung-Dong,Park, Soon-Dal 대한한방내과학회 1998 大韓韓方內科學會誌 Vol.19 No.2
The aim of the study was the experiment of the effect that Kami-Daesihotang had on the essential hypertension and hyperlipidemia. Rats were orally administered with Kami-Daesihotang for 30days and the constituent of the plasma and serum were analysed at the 10th, 20th and 30th day from the first day of experiment, respectively. The heart rate, blood pressure, plasma renin activity, plasma level of aldosterone, catecholamine, sodium and angiotensin II were measured after an oral administration of Kami-Daesihotang in SHR. In addition, serum levels of total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol and total lipid were measured with cholesterol-fed rats. The results were summarized as following ; 1. Single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang remarkably decreased the blood pressure in SHR. 2. Double-dosage Kami-Daesihotang were recognized as having the effect on the decreased of the pulse rate in SHR. 3. Plasma renin activity was significantly decreasd in SHR after single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang treatment. 4. Double-dosage Kami-Daesihotang considerably reduced the plasma angiotensin level in SHR. 5. Noticeable decreased of plasma norepinephrine level was showed in SHR, after single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang treatment. 6. Single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang noticeable reduced body weight in hyperlipidemia rats which had fed with 1% cholesterol. 7. Single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang had a significantly decreasing effect on serum total cholesterol in hyperlipidemia rats which had fed with 1% cholesterol. 8. Serum triglyceride level was importantly decreased in hyperlipidemia rats which had fed with 1% cholesterol, after single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang treatment. 9. Remarkable decreased of serum low density lipoprotein cholesterol level was found in hyperlipidemia rats which had fed with 1% cholesterol, after single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang treatment. 10. Double-dosage Kami-Daesihotang was showed a significantly decreasing effect on serum total lipid level in hyperlipidemia rats which had fed with 1% cholesterol. 11. Single-dosage Kami-Daesihotang noticeably reduced organ weight of liver, kidney, spleen and testis in hyperlipidemia rats which had fed with 1% cholesterol. Double-dosage Kami-Daesihotang significantly decreased organ weight of liver, kidney and spleen in hyperlipidemia rats. These Findings suggest a possible anti-hypertensive and hyperlipidemic effect of Kami-Daesihotang.
미성숙 랫드 자궁비대반응시험을 이용한 DEHA의 내분비계 장애작용 평가
박기대,한범석,정자영,오재호,조완섭,조민정,최미나,김성준,김승희,Park, Ki-Dae,Han, Beom-Seok,Jeong, Ja-Young,Oh, Jae-Ho,Cho, Wan-Seob,Cho, Min-Jeong,Choi, Mi-Na,Kim, Sung-Joon,Kim, Seung-Hee 한국환경보건학회 2007 한국환경보건학회지 Vol.33 No.5
This study was aimed to investigate the estrogenic activity of Di-(2-ethylhexyl) adipate (DEHA) using immatured type uterotrophic assay. SD rats were treated with DEHA (40, 200, 1000mg/kg/day), estradiol-3-benzoate (EB) $(1{\mu}g/kg/day)$ as positive control on the assay. In immatured-type uterotrophic assay, relative organ weights of kidney and reproductive organs such as ovary at high-dose group were significantly increased compared to those of vehicle control group. DEHA did not influence the levels of serum FSH and LH, and uterine morphological changes such as luminal epithelial height, myometrial thickness and numbers of uterine gland, and BrdU indices. In these results, there was no significant variation by DEHA treatment, suggesting that DEHA appears not to be a endocrine disrupter with estrogenic activity.
해석적 방법을 통한 3 축 공작기계의 기하학적 오차 민감도 분석
박성령(Sung Ryung Park),양승한(Seung Han Yang) 대한기계학회 2012 大韓機械學會論文集A Vol.36 No.2
본 연구는 3 축 공작기계에 있어 기하학적 오차가 체적 오차에 미치는 영향을 해석적 방법으로 분석하는데 목적이 있다. 먼저 기하학적 오차가 공작기계의 체적 오차에 미치는 영향을 제시하는 수학적 모델인 오차합성모델에 대해 분석한다. 민감도 분석은 분산 기반의 방법(Variance based method)을 사용하였으며 해석적 방법으로 분석하기 위해 평균 및 분산에 대해 목적 함수의 유형별로 그 해를 제시한다. 마지막으로 3 축 공작기계의 예를 들어 민감도 분석을 하였다. In this paper, an analytical method is used to perform a sensitivity analysis of geometric errors in a three-axis machine tool. First, an error synthesis model is constructed for evaluating the position volumetric error due to the geometric errors, and then an output variable is defined, such as the magnitude of the position volumetric error. Next, the global sensitivity analysis is executed using an analytical method. Finally, the sensitivity indices are calculated using the quantitative values of the geometric errors.