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박상만(Sang-Man Park),고관석(Gwan-Seouk Ko) 한국엔터테인먼트산업학회 2012 한국엔터테인먼트산업학회논문지 Vol.6 No.4
Event diagnosis after a reactor trip is very important for plant safety in a nuclear power plant. However, the current human reliability analysis(HRA) does not appropriately evaluate the effect of such a diagnosis failure to the plant safety. This paper shows, based on a simulation study, the potential of a diagnosis failure is much higher than what we expect. About 100 simulation experiments with six scenarios were performed to ascertain the potential of a diagnosis failure of an initiating event after a reactor trip. The diagnosis time and diagnosis error probability have been estimated and even though the estimation might have some restriction in the representative simulated scenarios and population size, it shows clearly that the effect of a diagnosis failure to the plant safety could not be disregarded.
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박도중,Ho-Jin Lee,김지선,Bon-Wook Koo,서윤석,Jung-Man Lee,한동석,Sang Hyun Hong,이한홍,Young Chul Yoo,Hyoung-Il Kim,Ji Yoon Rho,윤홍만,김하연,허훈,Hyae-jin Kim,Chang In Choi,Boohwi Hong,이상일,Kibeom Park,Seung Wan Ryu 대한위암학회 2025 Journal of gastric cancer Vol.25 No.3
Purpose This study aimed to identify the current perioperative management practices for gastric cancer surgery in South Korea and develop a consensus-driven Enhanced Recovery After Surgery (ERAS) protocol for a multicenter randomized controlled trial (RCT). Materials and Methods A survey was conducted with 20 principal investigators, comprising one gastric surgeon and one anesthesiologist each, from 10 tertiary hospitals in South Korea who participated in a planned multicenter RCT. The survey included 41 questions regarding ERAS implementation and department-specific perioperative management practices. The responses were analyzed using descriptive statistics, and the findings were used to develop a consensus-driven ERAS protocol. Results A total of 20 participants completed the survey. Most respondents estimated the overall compliance rate with ERAS protocols for gastric cancer surgery to be 30%–50%. A major barrier to ERAS implementation is limited personnel resources. The survey revealed significant variability in perioperative practices—particularly in postoperative oral feeding protocols and expected discharge dates—across institutions. Most institutions practice water fasting from midnight before surgery, and the adoption rate of multimodal opioid-sparing analgesia is low. Based on these findings, an ERAS protocol was established through collaborative discussions to shorten perioperative fasting periods and implement multimodal opioid-sparing analgesia. Conclusions This study revealed significant variability in the perioperative management of gastric cancer surgery in South Korea. A consensus-driven ERAS protocol was established to standardize care and promote functional recovery. Its feasibility and effectiveness should be evaluated in an upcoming multicenter RCT.
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환경친화적 캡스기초공법의 현장 타설 콘크리트 최적 배합비
박종만 ( Jong-man Park ),이경동 ( Gyeong-dong Lee ),한상호 ( Sang-ho Han ) 한국환경기술학회 2021 한국환경기술학회지 Vol.22 No.1
About 95 % of the foundations of buildings with three or more stories in Korea are constructed on a Pile Foundation, and such Pile Foundation has problems such as excessive construction costs, environmental problems due to the use of heavy equipment, and delays of construction due to frequent public resentment. In order to solve these problems, eco-friendly and cast-in-place Caps Foundation was developed that directly pours concrete on site. In this paper, to find the optimal mixing ratio of early strength concrete to be applied to the cast-in-place Caps Foundation, the changes in compressive strength, splitting tensile strength, and flexural strength of three concrete types of different cements by age were examined. As a result, all three concretes satisfies the target values of 21 MPa of compressive strength and 3 MPa of flexural strength at 5 days. Especially, EPC using early strength portland cement reached the target values after 3 days. Therefore, it was decided to use the mixture of BFC using blast furnace slag cement as the optimal mixing ratio, and to use the mixture of EPC using early strength portland cement at the special field where additional time reduction is required.
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길경 Saponin이 고지방식이를 한 흰쥐의 혈청, 간장 및 분변 지질 함량에 미치는 영향
박무희(Mu-Hee Park),이영주(Young-Ju Lee),황성원(Sung-Wong Hwang),한준표(Jun-Pyo Han),배만종(Man-Jong Bae) 한국식품영양과학회 1994 한국식품영양과학회지 Vol.23 No.4
6주간 고지방식이를 섭취한 흰쥐에 있어서 길경 saponin이 지방 축적 억제와 대사에 미치는 영향을 검토하고자 혈청과 간장 및 분변 중 지방 성분을 생화학적으로 분석하여 다음과 같은 결과를 얻었다. 1. 혈청 및 간장중의 총지질, 총콜레스테롤 및 중성지방 함량은 길경 saponin군이 대조군에 비하여 유의한 감소를 보였다. 2. 분변 중 총지질 및 총콜레스테롤 함량은 대조군과 비교할 때 길경 saponin군이 다소 배설이 증가되었으나, 유의성은 인정되지 않았다. This study was conducted to investigate the effect of Platycodi radix saponin (PRS) on the reduction of lipid status in rats fed on high fat diet for 6 weeks after which lipid contents were measured in serum, liver and feces. The results obtained from this study are as follows; That the levels of total lipid, total cholesterol and triglyceride in serum and liver were significantly lower in the PRS group as compared with the control group. The contents of total lipid and total cholesterol excreted in the feces were tended to be slightly increase in PRS group compared to the control group, which were not significant.
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박재만 ( Jae Man Park ),최재성 ( Jae Sung Choi ),나주옥 ( Ju Ock Na ),김용훈 ( Yong Hoon Kim ),서기현 ( Ki Hyun Seo ),오미혜 ( Mi Hye Oh ),조성식 ( Sung Shick Jou ) 대한내과학회 2011 대한내과학회지 Vol.81 No.3
Benign metastasizing pulmonary leiomyoma is a rare disease that is usually detected several years after hysterectomy or myomectomy. Recently, we experienced two cases, one with monthly chest pain and the other without symptoms, which were diagnosed with benign metastasizing leiomyoma in the lung. A 48-year-old woman who underwent hysterectomy 12 years earlier was referred to us because of multiple pulmonary nodules on chest radiography, and chest pain for 6 months. Thoracoscopic tumor excision was performed. Pathologically, she was diagnosed with benign metastasizing leiomyoma in the lung. After that, chest computed tomography showed tumors with a progressive reduction in size. The other 48-year-old woman, who had undergone myomectomy for uterine leiomyoma 8 years before, visited our hospital for evaluation of incidentally revealed bilateral multiple nodules on chest radiography. The microscopic finding of percutaneous transthoracic needle biopsy revealed a benign pulmonary metastasizing leiomyoma originating from uterine leiomyoma. Multiple nodules on chest radiography were more increased than those performed 1 year and 3 months prior to admission. However, chest X-ray showed tumors that had progressively decreased in size at 6 months after diagnosis of menopause. (Korean J Med 2011;81:387-392)
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상피성 난소종양에서 SPARC 발현과 임상병리학적 연관성에 관한 연구
박상일 ( Sang Il Park ),이의돈 ( Eui Don Lee ),서동수 ( Dong Soo Suh ),김기형 ( Ki Hyung Kim ),윤만수 ( Man Soo Yoon ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.12
Objective Secreted protein acidic and rich in cysteine (SPARC) is an extracellular matrix-associated protein implicated in the modulation of cell adhesion, migration, cell cycle regulation, and angiogenesis. It has been associated with the progression or suppression of various cancers. This study was aimed at correlating SPARC protein expression with tumor progression and clinicopathological features in ovarian epithelial tumors. Methods Epithelial ovarian cancer (n=69), borderline tumor (n=18), benign tumor (n=10) and normal ovary tissues were obtained after operation. SPARC protein expression was examined using immunohistochemistry. With a retrospective review, patients` characteristics and slide samples were analyzed. Results Cytoplasmic SPARC immunoreactivity was observed in stromal cells in nearly all cases of normal ovary, benign and borderline tumors (100%, 94.7%, and 100%). In contrast, SPARC was detected in the stroma of 63.8% (44/69) and the score of immunoreactivity was significantly reduced in malignant tumors (P<0.001). SPARC expression in ovarian epithelial cancers was significantly associated with International Federation of Gynecology and Obstetrics stage. However, it was not correlated with other clinicopathologic parameters, including histologic type, tumor grade, nuclear grade, mitosis, tumor size, local recurrence, distant metastasis, and survival. Conclusion This study showed that reduction of SPARC expression in ovarian epithelial tumors is significantly correlated with tumor invasiveness and SPARC may act as tumor suppressor.
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