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      • SCOPUSSCIEKCI등재

        비전형적 MRI 소견을 가진 뇌하수체농양 1례 - 증례보고 -

        박상우,황성남,박승원,김영백,최덕영,Park, Sang Woo,Hwang, Sung Nam,Park, Seung Won,Kim, Young Baeg,Choi, Duck Young 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.7

        A sixty-three year old woman presented with sudden onset of dystonic twitching of the extremities and repeatedly downgrading of consciousness in the midnight. She had no history of medical illness in the past but had been suffered from fatigue recently before the onset of the attack. At admission she was neurologically free including neuro-ophthalmologic examination. MRI showed a high signal T1WI mass in the sella protruding into the suprasellar cistern. Hormonal study revealed low value of T3, T4, LH and FSH. Under the impression of pituitary apoplexy she underwent operation via transcranial route. When the protruding diaphragma sellae was opened, milkish pus spilled out. The thick capsule was biopsied and pus was sent for the study. The results of Gram staining and culture were both negative but pathologic report of the specimen was high infiltration of lymphocytes with few polymorphs.

      • 메타데이터 교환표준(XMI)을 이용한 분산 이종 GIS 데이터베이스 검색

        박상우,유상봉,Park, Sang-Woo,Yoo, Sang-Bong 한국공간정보학회 2000 개방형지리정보시스템학회 논문지 = Journal of the Korea Open Geogr Vol.2 No.1

        As the networks proliferate all over the world and the application of the geographical information increase recently, the importance of effective access and exchange of GIS data is recognized. However, existing GIS data are generated by many different organizations without proper standard methodologies and data exchange facilities such as clearing houses are being operated on different DBMS with their own schemata. It makes difficult for users to access and utilize the GIS data even the data are open to public. In this research, we provide the users a search system that interfaces heterogeneous repository systems. In order to interact heterogeneous DBMS we utilize the metadata interchange standard (XMI) from OMG. 최근 네트웍의 보급과 지리정보의 활용이 증가하면서 효과적인 지리정보의 검색과 접근에 대한 중요성이 강조되고 있다. 하지만 기존의 GIS 데이터는 지리적으로 분리된 여러 부서나 조직에서 생성 및 관리되고 있으며, 공간 정보 유통을 위한 클리어링하우스 등이 서로 다른 DBMS 상에서 독자적인 스키마를 가지고 개발되어 있다. 이러한 이질적인 구조와 구현 환경으로 인해 일반 사용자들이 서로 다른 GIS 데이터베이스를 접근하여 검색하는데 많은 어려움이 따르고 있다. 본 연구에서는 OMG의 메타데이터 교환 표준인 XMI로 표현된 이질적인 GIS 데이터베이스의 메타데이터를 통하여 사용자에게 각 데이터베이스의 구현 환경과 스키마에 독립적인 공간 데이터를 검색 기능을 제공하는 검색 시스템을 구현하였다.

      • KCI등재후보

        해리수직편위에서 단안 수술의 효과

        박상우,정태선.Sang Woo Park. M.D.. Tae Sun Jeong. M.D. 대한안과학회 2006 대한안과학회지 Vol.47 No.6

        Purpose: To investigate changes in the unoperated eye of patients who underwent unilateral surgery for asymmetrical dissociated vertical deviation. Methods: We performed superior rectus recession and inferior oblique anterior transposition in the case of asymmetrical dissociated vertical deviation, and lateral rectus recession in the case of dissociated horizontal deviation. We excluded patients having a history of previous operation on the vertical rectus muscles, oblique muscle in the unoperated eye, nystagmus, neurologic problems, and imprecise measurement of deviation angle. Changes in the unoperated eyes of 11 patients who underwent unilateral surgery to correct asymmetrical dissociated vertical deviation in the other eye, from May 2003 to April 2004 were analyzed retrospectively at 1 year postoperative. Results: Not all cases of preoperative latent dissociated vertical deviation manifested such deviation in the unoperated eye postoperatively. Conclusions: Unilateral surgery is an effective treatment in patients with asymmetrical dissociated vertical deviation and does not affect the unoperated eye.

      • KCI등재

        도졸라마이드-티몰롤과 라타노프로스트가 가토 방수의 산화환원계에 미치는 영향

        박상우,이승현,문귀형,Sang Woo Park,MD,Seung Hyun Lee,MD,Gui Hyeong Mun,MD 대한안과학회 2009 대한안과학회지 Vol.50 No.3

        Purpose: To evaluate the effect of dorzolamide-timolol and latanoprost on redox cycle of superoxide dismutase (SOD) and ascorbic acid in the aqueous humor of the rabbit. Methods: Group 1 (20 eyes of 10 rabbits) was instilled with dorzolamide-timolol in the right eye and Group 2 (20 eyes of 10 rabbits) was instilled with latanoprost in the same manner. Four weeks after instillation, SOD activity and ascorbic acid concentration were analyzed. Results: In Group 1, SOD activity and ascorbic acid concentration of the right eye and left eye were 15.7% and 19.3% (p=0.27), 2.7 pM and 2.6 pM (p=0.47), respectively. In Group 2, SOD activity and ascorbic acid concentration of the right and left eye were 22.3% and 27.6% (p=0.14), 2.3 pM and 2.1 pM (p=0.89), respectively. Conclusions: There was no significant difference of SOD activity and ascorbic acid concentration between both eyes in Group 1 and 2.

      • SCOPUSKCI등재
      • KCI등재

        야관청혈탕이 고지방식이로 유도된 흰쥐의 비만 억제에 미치는 영향

        박상우,조충식,김철중,Park, Sang-Woo,Cho, Chung-Sik,Kim, Chul-Jung 대한한방내과학회 2011 大韓韓方內科學會誌 Vol.32 No.2

        Background : Obesity, the syndrome caused by a high fat diet, is a disease. At the same time, obesity causes diabetes mellitus, hyperlipidemia, and cardiovascular disease. Recently, its prevalence rate is increasing. Yagwan-cheunghyeoltang (YCT) used in this experiment is the prescription of Yagwanmoon added to Cheunghyeol-tang which is reported to be very effective in weight loss controlling and serum cholesterol. It is also reported that Yagwanmoon has significant antioxidant effects and YCT has a significant effect on blood glucose control. Objectives : This study was conducted to experimentally evaluate the effects of YCT on obesity in rats induced by high fat diet. Methods : The experiment was conducted with 4-week-old male rat s divided into 5 groups. They were a normal diet group, a high fat diet group, a positive drug control group, a 1% YCT group, and a YCT 3% group, and were tested for eight weeks. After four weeks of inducing obesity by a high fat diet, rats were allowed to lose weight by following the normal diet group, approximately 30% compared with 10 rats in each group were determined as still obese. Changes in body weight and organ weight and serum cholesterol, triglyceride, glucose-density, low density lipoprotein cholesterol, antioxidant activity were checked. Results : In the experimental groups, we observed weight loss and visceral fat reduction, improvement of liver function, reduction of serum glucose, activation of HMG-CoA reductase inhibitor, reduction of concentrations of leptin and it showed a significant effect on antioxidants and lipid peroxidation. Conclusions : YCT has significant effects on the regulation of hyperlipidemia and lipid peroxidation associated with obesity and has significant effects on, antioxidants and lipid peroxidation, too. Additional clinical studies are needed.

      • KCI등재

        보기제통탕이 말초신경병증 모델에서 신경 손상 회복에 미치는 영향

        박상우,김철중,조충식,Park, Sang-Woo,Kim, Chul-Jung,Cho, Chung-Sik 대한한방내과학회 2013 大韓韓方內科學會誌 Vol.34 No.4

        Objectives : Effects of Bogijetong-tang (BJT) on peripheral nerve regeneration have been reported in a previous study on BJT but additional study on a damaged peripheral neuropathy where its damage level is physically and chemically more severe was needed. Plus, this study was conducted because there haven't been any studies for BJT on central nerve regeneration. Methods : In order to check the effect on central nerve regeneration, the study on cerebellum cells was started and the sciatic nerve was used to observe the effects on a peripheral nerve which was severely damaged both physically and chemically. Nerve recovery effects were observed by analyzing target proteins such as phospho-extracellular signal-regulated kinase, ${\beta}1$ integrin, neurofilament 200, growth-associated protein-43, cyclin-dependent kinase 1, phospho-vimentin, phospho-Smad, and caspase 3. Results : The significant changes of target protein in cerebellum neurons have been observed. The changes of index protein on the axon regeneration and the nerve recovery in the sciatic nerve have been observed and the effects on cell protection were observed, as well. Conclusions : This study confirmed that BJT made a significant influence on nerve protection and recovery of a damaged peripheral neuropathy and it also made a possibility of its regeneration in a damaged central nerve injury.

      • KCI등재

        내사시에서 양안 내직근후전술 시 기능적적도부 및 팍스의 수술양을 고려한 군 간 수술성적비교

        강병완,박상우,윤경철,허환,Byung Wan Kang,MD,Sang Woo Park,MD,PhD,Kyung Chul Yoon,MD,PhD,Hwan Heo,MD,PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.1

        Purpose: To compare the surgical outcomes of functional equator-considering and Parks’ methods in infantile esotropia and partially accommodative esotropia. Methods: The medical records of 96 patients with infantile esotropia and partially accommodative esotropia who underwent bilateral medial rectus muscle recession by functional equator-considering and Parks’ methods were reviewed retrospectively. The surgery success rate at 1 month, 3 months, 6 months and 12 months was compared by the deviation angle measurement. Results: Overall success rates were not statistically different between the 2 groups. Additionally, there were no differences in surgical success rate of functional equator-considering and Parks’ methods in infantile esotropia and partially accommodative esotropia. When the patients were divided into 2 groups based on 40 PD, no significant difference in success rate between the 2 groups was observed. When patients were divided into 2 groups based on 22 mm of axial length, there was no statistical difference observed. Postoperative overcorrection was 2 (4%) in the functional equator group and 3 (6.5%) in Parks’ method group and postoperative undercorrection was 9 (18%, 19.6%) in each group. The incidence of undercorrection in the Parks’ method group was significantly higher in the greater than 22 mm axial length group (7, 35.0%) than in the less than 22 mm group (2, 7.7%) (p = 0.029). Conclusions: There was no statistically significant difference in surgical success rate between the functional equator and Parks’ methods in infantile esotropia and partially accommodative esotropia. J Korean Ophthalmol Soc 2012;53(1):138-144

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