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비혈연간 조혈모세포이식 후 재발한 만성골수성백혈병에서 Gleevec에 의한 완전관해 및 공여자 조혈 재건 1예
박사라,김우건,이제환,최성준,형철호,손희정,강혜진,지형석,이정신,이규형 대한조혈모세포이식학회 2002 대한조혈모세포이식학회지 Vol.7 No.2
저자들은 만성골수성백혈병으로 동종 골수이식 후 림프구성급성전환으로 재발한 환자에서, Gleevec 투약 후 DLI (donor lymphocyte infusion) 없이 공여자 조혈(donor hematopoiesis)의 재건이 이루어지고, 세포유전학적, 분자생물학적 기준에서 모두 완전관해에 이르고, 12개월째 관해를 유지하고 있는 환자를 경험하였기에 이를 보고하는 바이다. 본례의 환자에서 Gleevec은 동종 골수이식 후 급성전환기로 재발한 환자에서도 매우 효과적인 것으로 나타났다. Gleevec은 동종 골수이식 후 재발한 만성골수성백혈병에서 Interferon-α, DLI, 2차골수이식 등 기존의 치료의 문제점을 보완할 수 있는 유용한 치료방법으로 사용될 수 있을 것으로 생각되며, 이의 장기적 치료효과의 평가와 기존치료와의 병합요법의 유용성 등에 대한 향후 연구가 필요할 것으로 생각된다. We report a 32-year old woman with chronic myelongenous leukemia (CML) in lymphoid blast crisis, who underwent allogenic bone marrow transplantation (BMT) from HLA phenotype full mached unrelated donor. Her disease relapsed into full-blown blast crisis. Upon treatment with gleevec, she achieved immediate remission of leukemia as well as the donor type hematopoiesis without donor lymphocyte infusion (DLI). Our case suggests the high effectiveness of gleevec in CML relapsed after allogeneic BMT. Further studies are needed to define the role of gleevec (with or without DLI) in the management of CML relapsed after allogeneic BMT.
Ein Feste Burg Ist Unser Gott Its Introduction, Reception and Effect in Korea
박사라 장로회신학대학교 기독교사상과문화연구원 2016 장신논단 Vol.48 No.3
The purpose of this article is to analyze how the German hymn of Martin Luther’s song lyrics Ein feste Burg ist unser Gott (A mighty fortress is our God ) has been transferred to the Korean hymnal and to explore the historical and actual influence of that hymn in Korea. The hymn is contained both in the German hymnal Evangelisches Gesangbuch and the Korean 21 st Century Hymnal. However, there are several differences between the two hymnals. First of all, the two hymnals will be compared and it will be shown which differences can be noticed between the two versions. On the basis of the comparison the study will be extended on the reasons of these findings which relate to the history of Christian mission in Korea. Thereafter, the influence of the hymn on Korean Christians will be explored. The hymn played a great part in Korean history: Under the Japanese regime (1910–45), the Korean Church and the Korean believers participated in the liberation movement for their country singing Ein feste Burg ist unser Gott. Furthermore, this hymn gave strength and comfort to the Korean Christians who didn’t accept the Japanese religion of Shintoism. Nowadays, the hymn can be heard not only in church but also on the stage: In 2011, Park Chae Hoon composed the opera Son Yang Won which includes Ein feste Burg ist unser Gott. This study will demonstrate and explain the independent reception of the German hymn in Korea.
통합예술치료가 발달장애아동과 비장애형제자매와의 관계향상에 미치는 영향
박사라 한국예술치료학회 2012 한국예술치료학회지 Vol.12 No.2
본 연구는 통합예술치료가 발달장애아동과 비장애형제자매의 관계향상에 미치는 영향 을 알아보고자 하였다. OO광역시 장애부모회에서 형제관계 척도 및 어머니(아버지)가 지각한 형제관계 척도의 점수가 낮은 학령기의 형제자매 12쌍 중 통합예술치료 참여 를 희망하는 9쌍을 선정하였으며, 중도탈락자를 뺀 나머지 5팀을 최종 연구대상으로 하였다. 실험집단을 대상으로 주1회 90분 총18회기의 통합예술치료 프로그램을 실시 하였다. 통합예술치료 프로그램이 발달장애아동과 비장애형제자매의 관계향상에 미치 는 영향을 알아보기 위해서 회기별 행동 관찰분석, KHTP 그림검사, KFD그림검사, 형 제관계 척도, 어머니(아버지)가 지각한 형제관계 척도를 사용하였다. 이에 본 연구에 서 밝혀진 결과를 요약하면 통합예술치료프로그램이 발달장애아동과 비장애형제자매 관계에 긍정적으로 영향을 미쳤다.
Statistical studies of trough at middle latitudes observed by DMSP F15
박사라,길효섭,김관혁,Park, Sarah,Kil, Hyosub,Kim, Khan-Hyuk 한국천문학회 2012 天文學會報 Vol.37 No.2
The middle-latitude ionization trough, the plasma density depletion in the subauroral region, has been extensively studied since its discovery in the 1960s. Our knowledge of the variability of the trough is mostly based on the observations in the northern hemisphere. Recently, the COSMIC observations enabled the investigation of the trough in both hemispheres at all local time. However, the investigation was limited to the period of the low solar activity. In this study, we investigate the variability of the trough location and morphology with local time, solar cycle, magnetic activity, and interplanetary magnetic field. For this purpose, we analyze the DMSP F15 data acquired during 2000-2010.
품종 및 입자크기별 건식 쌀가루를 이용한 증편의 품질 특성
박사라,김경미,김희선,라하나,한귀정 한국식생활문화학회 2018 韓國食生活文化學會誌 Vol.33 No.6
In this study, the particle size and varieties(Samgwang, Boranchan, Hanareum, Dasan, Hangaru) of dry-milled rice flour were used to manufacture Jeung-pyun and its quality characteristics were analyzed. The appearance of Jeung-pyun showed that high dense pores were formed which Samgwang, Dasan and Hangaru milled rice flour with particle size. The volume of Jeung-pyun, only Hanareum showed not significantly difference according to particle size. Samgwang, Boranchan and Dasan varieties of particle size of 150 μm, their volume were significantly decreased(p<0.05). Result of the pH, all of particle size, Samgwang showed significantly lowest(p<0.05). While Sweetness of Samgwang varieties were significantly highest 3.27-3.63 °Brix(p<0.05). Particle size of rice flour were increased, hardness of Jeung-pyun analyzed significantly strong(p<0.05). The highest acceptance of Jeung-pyun for the volume and bitter taste when particle size of 50 μm milled by Hanareum. When the particle size was 50 μm, the overall acceptance was evaluated as the highest value for Jeung-pyun made from Samgwang and the second high score made from Hanareum. As a result, particle size of rice flour was 50 μm, the acceptance of all the sensory characteristics was high. When appearance of Jeung-pyun measured, Samgwang showed a dense structure and low hardness. Hanareum showed high increasing volume and springness. We suggest that the Samgwang and Hanareum were found to be the most suitable varieties for the production.