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        • KCI등재

          Upgraded Malignancy from High-Risk and Borderline Breast Lesions: Immunohistochemical and Clinical Characteristics

          박보림,강봉주,백지은,김성헌,이현실 대한영상의학회 2018 대한영상의학회지 Vol.78 No.1

          Purpose: The purpose of this study was to investigate the immune-histochemical characteristics of upgraded malignancy from high-risk and borderline breast lesions, and to correlate the upgrade rates with clinical findings. Materials and Methods: We scrutinized image-guided biopsy records retrospectively, and included all women afflicted with high-risk and borderline breast lesions during the period, 2011 to 2015, inclusive. A total of 340 high-risk and borderline lesions were identified by the pathologist in biopsy samples and thereafter, surgical excision and/or image follow-up for at least 24 months was performed. We compared the clinical emanating from both high-risk and borderline lesions, and with and without cancer upgrade. In the instances of lesions with cancer upgrade, histologic and immuohistochemical reviews were performed. Results: Of the 340 high-risk or borderline lesions, 18.8% (64/340) were upgraded. The upgrade rates were higher in patients of more advanced age, larger body habitus and afflicted with atypical ductal hyperplasia rather than with other pathology (p < 0.05). In the lesions with cancer upgrade (n = 64), there was no lymph node metastasis. The estrogen receptor-positive (93.8%), progesterone receptor-positive (87.5%), human epidermal growth factor receptor type 2-negative (90.6%), Ki-67-negative (82.8%), and Luminal A (76.6%) types were seen more frequently. Conclusion: Most upgraded malignancies arising from high-risk and borderline breast lesions were found to be Luminal A-type with good prognostic factors, and the upgrade rates correlated with clinical characteristics.

        • 경피적 중심 정맥 도관의 임상적 적용에 관한 연구

          이희경,김영창,이혜경,박보림 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.1

          신생아실에서의 미숙아 및 선천성 기형의 치료의 발달과 함께 중심 정맥의 필요성이 증가되면서 경피적 중심 정맥 확보인 경피적 정맥 도관(PCVC)을 시행하게 되었으며 현재 널리 이용하계 되었다. 1995년 5월에서부터 1997년 4월까지 본원 신생아실에서 경피적 정맥 도관을 시행받은 78례에 대상으로 후향적으로 성공률의 유무, 도관 유지, 문제점, 합병증등을 알아 보아 향후 치료에 도움을 얻고자 본 연구를 시행하였다. 1. 경피적 정맥 도관을 시행한 78례중 64례(80.8%)에서 시술에 성공하였으며 본 시술만 전담하는 간호사에 의해 시행한 1997년 1월에서 4월까지 성공률은 95.3%였다(p<0.001). 2. 73.1%가 총정맥 영양법을 위해 시행되었고 이중 43.6%가 미숙아로 인한 총정맥 영양법을 위해 본 시술이 필요하였으며 17.9%는 항생제를 포함한 장기간의 약제 사용을 위한 정맥 확보를 위해, 9%에서 고농도의 용액의 사용을 위해 시술되었다. 3. 시술 부위는 주관절 정맥이 59.4%로 가장 많았고 액와 정맥이 35.9%로 많았다. 4. 시술후 도관의 위치는 우심방이 44.9%, 상대 정맥이 12.8%, 액와 정맥이 21.8%, 하대 정맥이 1.3%, 무명정맥이 1.3%로 우심방과 상대 정맥에 위치한 경우와 그이외 말초 부위에 위치한 경우를 비교했을 때 우심방과 상대 정맥에 위치한 경우가 도관의 유지기간이 의의있게 길었다(p<0.001). 5. 도관 제거의 이유는 더 이상 수액 제제가 피료치 않아 계획적으로 제거된 경우가 56.3%, 기계적 폐색등으로 제거된 경우가 21.9%, 도관과 관련된 감염으로 제거된 경우가 3%순이었다. 6. 도관 제거후 배양 검사를 시행한 36례중 9례(25%)에서 균이 배양되었고 staphylococcus epidermidis와 candida albicans가 대부분을 차지하였다. Percutaneous central venous catherization(PCVC) is performed commonly as a vascular access procedure for a various indications in the neonatal intensive care unit (NICU). We evaluated a total of 78 PCVC cases performed in the NICU over 2 years from April, 1995 to April, 1997 in terms of age, success rate, indications, insertion sites, indwelling time and causes of removal of catheters, and associated complications including sepsis retrospectively. The results are described below ; 1. Patient ages and body weights at the time of insertion ranged from 1-120 days (average age, 10.9 days) and from 660-4,100 gm(average weight, 2,119 gm) respectively. 2. The overall success rate of insertions was 80.8%, however, the insertions attempted by highly- trained nurse were successful in 95.3 % from Jan. to April, 1997. 3. The most common indication was total parenteral nutrition (73.1%). 4. The insertion sites were cubital vein(59.4%), axillary vein(35.9%), and external jugular vein(3.1%). 5. The locations of catheter tip were right atrium(44.9%), axillary vein(21.8%), superior vena cava(12.8%), and inferior vena cava(1.3%). 6. The indwelling time ranged from 1-52 days (average, 12.6 days). When the catheter tips were placed in the right atrium or superior vena cava, the catheter was placed in the longer duration compared to those of other sites significantly. 7. The causes of removal of catheter were elective (56.3 %), mechanical obstruction(21.9%) and catheter related infection(3%). 8. The cultures of catheter tip were done after removal in 36 cases, among them cultures were positive in 9 cases(25%) the most common causes were S. epidermidis and Candida albicans.

        • 초기 모유수유시 산모의 불편감과 교육요구

          박보림,엄영란 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.1

          BACKGROUND: While it was emphasized the advantages for breast-feeding and recommanded breast-feeding, it was least to solve the mother's probems in breast-feeding. To continue breast-feed, the mothers need be probided the care for the early problems. METHODS: We interviewed 62 women with questionaire during puerperium(2-31days) in Soonchunhyang Chunan Hospital OB unit. They were breast-feeding. RESULTS: The experience at early breast-feeding was very positive, which were 'the realization of role transition, the formation of attachment, the feeling of happiness. The best important problems of early breast-feeding were 'baby falls asleep, leaking breasts, and worry about insuffcient milk because of small breasts'. The maternal learning needs were significantly related with the problems that they really experienced. CONCLUSION: The education about breastfeeding and its problems should be based on the maternal learning needs and their experience. And the method of educaton should be changed from topic-oriented to problem-solving.

        • KCI등재

          1인가구의 주택점유형태

          박보림(Park, Bo-Lim),김준형(Kim, Jun-Hyung),최막중(Choi, Mack Joong) 대한국토·도시계획학회 2013 國土計劃 Vol.48 No.1

          It has been generally accepted that the single-person households prefer renting to owning. This hypothesis supports the governmental policy increasing rental housing provision. However, it has been also found that single-person households are so heterogeneous in terms of housing demand. Based on the 2010 Korean Welfare Panel Study (KOWEPS), this paper analyzes the effect of single-person household on the tenure choice. The preference for rental housing among single-person households is still observed. However, when breaking down the total sample into age/income groups, this pattern is statistically significant only for the middle-aged and ageing households or middle-income households. In addition, being single-person household affects the impact of age and income on the tenure choice. These results imply that before providing rental housing based on the increasing single-person households, the analysis should be performed about the age or income-composition of them.

        • 무인검사장비를 활용한 교량 손상정보 통합관리코드 제안

          재봉,정일원,신병길,보림,이덕근 한국구조물진단유지관리공학회 2017 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.2017 No.04

          In this study, the integrated management code of damage information in bridges using the data from unmanned inspection equipment (i.e., drone with hybrid imaging equipment) was proposed. It was found that the integrated management code could be used in developing bridge management system based on 3-dimensional information model of bridge.

        • 무인검사장비를 활용한 교량 손상정보 통합관리코드 제안

          재봉,정일원,신병길,보림,이덕근 한국구조물진단유지관리공학회 2017 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.2017 No.0

          In this study, the integrated management code of damage information in bridges using the data from unmanned inspection equipment (i.e., drone with hybrid imaging equipment) was proposed. It was found that the integrated management code could be used in developing bridge management system based on 3-dimensional information model of bridge.

        • KCI등재

          산후조리원 이용여부에 따른 초산모의 신체적, 심리적 건강상태 및 모성역할적응의 변화양상에 관한 연구

          송주은,박보림 한국간호과학회 2010 Journal of Korean Academy of Nursing Vol.40 No.4

          Purpose: The purpose of this study was to compare levels of postpartum fatigue, depression, childcare stress, and maternal identity according to postpartum period between primiparas who used Sanhujori facilities and those who did not. Methods: The research design was a longitudinal descriptive study using self-report questionnaires. Participants were 55 healthy primiparas who delivered at one of 3 hospitals in Chungnam, 21 using Sanhujori facilities and 34 not using these facilities during the first three weeks after childbirth. Data were collected from October 2008 to April 2009 at three measurement points, 2-4 days after childbirth (T1), 4-6 weeks (T2), and 12-14 weeks (T3). Data were analyzed using the SPSS 17.0 WIN program. Results: There was a significant difference in childcare stress between the two groups at 4-6 weeks after childbirth. Postpartum depression and childcare stress at 4-6 weeks were significantly higher than those of the other postpartum periods, while maternal identity was significantly lower. Conclusion: Child care stress is the most important issue among women who use Sanhujori facilities and the 4-6 week period after childbirth is very difficult to primiparas. These results indicate that nursing interventions for primiparas in Sanhujori facilities should focus on reducing childcare stress. Furthermore proper follow-up programs at 4-6 weeks are needed to decrease the difficulties in adjustment by new mothers.

        • KCI등재

          Modulation of lipid metabolism by mixtures of protamine and chitooligosaccharide through pancreatic lipase inhibitory activity in a rat model

          강남희,이경원,보림,민아,이혜림,상기,황경아,형국,최경철 한국실험동물학회 2012 Laboratory Animal Research Vol.28 No.1

          Overweight and obesity are usually related with high fat and calorie intake, and seriously causative of lifestyle-related diseases such as cardiovascular disorders, arteriosclerosis, and colon cancer. In this study,we propose a novel dietary therapy against overweight and obesity using mixtures of protamine and chitooligosaccharide (COS), which are known to interrupt the lipid metabolism in the body. Protamine is a dietary protein originated from salmon reproductive organ, and COS is an oligosaccharide made from chitin or chitosan by chemical or enzymatic hydrolysis. In the enzyme activity analysis in vitro, protamine and COS strongly suppressed the activity of pancreatic lipase, which is the primary enzyme for the digestion and absorption of lipids in the intestine. In in vivo animal test, the mixtures of protamine and COS significantly reduced the serum levels of triglyceride (TG), total cholesterol (T-CHO), and low density lipoprotein-cholesterol (LDLC) and inhibited the accumulation of lipids in liver tissue of Sprague Dawley (SD) rats fed high fat diets. On the other hand, they increased fecal TG and T-CHO contents. From these alterations in lipid metabolism, we verified that protamine and COS mixtures could effectively interrupt the digestion and absorption of dietary lipids in the body by inhibiting pancreatic lipase activity. In addition, protamine and COS mixtures increased the serum level of high density lipoprotein-cholesterol (HDLC), responsible for removing cholesterol from cells and protecting atherosclerosis, and therefore decreased the potential risks of cardiovascular diseases by lowering values of the atherogenic index (AI)and cardiac risk factor (CRF). Taken together, we suggest protamine and COS mixtures as a prominent dietary therapy for the prevention of overweight, obesity, and further cardiovascular diseases related with hyperlipidemia.

        • KCI등재후보
        • KCI등재

          포커스 그룹 연구방법을 적용한 초산모의 산후조리원 이용 경험 분석

          송주은 ( Ju Eun Song ),채현주 ( Hyun Ju Chae ),박보림 ( Bo Lim Park ) 여성건강간호학회 2015 여성건강간호학회지 Vol.21 No.3

          Purpose: The purpose of this study was to examine the experiences of Sanhujori facility use among the first time mothers in Korea. Methods: A qualitative study was conducted, using focus group interview. Data were collected from the 24 first time mothers of 4 focus groups, who had given birth within 6 month and had used one of the Sanhujori facilities located in C province, Korea. After obtaining written informed consent from all participants, each session of the focus group was audio-taped and transcribed into verbatim. Data were analyzed using content analysis in order to identify significant themes. Results: Four major themes that emerged from the data were as follows. 1) Promoting postpartum physical recovery through a enough time with only focusing on herself, 2) Promoting postpartum psychological recovery through emotional and informational support with peer mothers, 3) Experiencing breast feeding difficulties and disappointing with unsatisfied help from health professionals, and 4) Lack of the professional education programs regarding parenting. Conclusion: Based on these results, it will be suggested that the various support programs by not only the peer mothers co-resided in Sanhujori facilities but also the health care professionals in the Sanhujori facilities should be developed for helping a "becoming a mother" of the first time mother in the Sanhujori facilities. In addition, qualified education and counseling program, especially for the successful breast feeding, should be provided by the health care professionals for improving mothering ability of the first time mother in the Sanhujori facilities.

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