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백굴채약침액(白屈菜藥針液)이 LPS로 유도(誘導)된 RAW 264.7 대식세포(大食細胞)에서의 항염증효과(抗炎症效果)
박동천 ( Dong Cheon Park ),박지현 ( Ji Hyeon Park ),이우경 ( U Kyung Lee ),이진규 ( Jin Kyu Leek ),서일복 ( Il Bok Seo ),김호현 ( Ho Hyun Kim ),김정선 ( Jeong Seon Kim ),김이화 ( Ee Hwa Kim ) 대한경락경혈학회 2004 Korean Journal of Acupuncture Vol.21 No.2
Objectives: Recently, Herbal-acupuncture therapeutics has been used for the treatment of inflammatory diseases such as rheumatoid arthritis. Especially, we have been interested in chemical mediators concerned with inflammation such as prostaglandin, cytokine, nitrous oxide. The purpose of this study is investigated that the effect of Chelidonii Herbal-acupuncture solution in lipopolysaccharide-stimulated RAW 264.7 macrophages, performed several expeimental items: those are prostaglandin E2, nitric oxide and cyclooxygenase-2. Methods: The cytotoxicity of Chelidonii Herbal-acupuncture solution in RAW 264.7 macrophages were measured by MTT-based cytotoxicity assay. In order to observe cyclooxygenase-2 mRNA expression in lipopolysaccharide-stimulated RAW 264.7 macrophages, RT-PCR was used. Prostaglandin E2 formation and nitric oxide production was measured by competitive enzyme immunoassay and Griess assay. Results: 1. The MTT assay demonstrated that cytotoxic effect of Chelidonii Herbal-acupuncture solution in RAW 264.7 macrophages were not appeared before concentration of 1㎎/㎖. 2. Chelidonii Herbal-acupuncture solution inhibited cyclooxygenase-2 mRNA expression in lipopolysaccharide-stimulated RAW 264.7 macrophages. 3. Chelidonii Herbal-acupuncture solution inhibited nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 macrophages. 4. Chelidonii Herbal-acupuncture solution inhibited prostaglandin E2 formation in lipopolysaccharide-stimulated RAW 264.7 macrophages. Conclusions: On the basis of these results, It was shown that Chelidonii Herbal-acupuncture solution is significantly able to inhibit the production of PGE2 and NO, as well as COX-2 mRNA expression. Our results may provide new mechanism by which Chelidonii Herbal-acupuncture solution accounts for its beneficial effect on accelerating wound healing and anti-inflammation.
박동천 ( Park Dong Cheon ) 한국구조물진단유지관리공학회 2017 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.21 No.1
The purpose of this study is to evaluate salt attack durability of the concrete structure which has experienced the fire. Mechanical properties and chloride ion diffusivity of concrete specimens were measured after 2 hours heating at 200℃, 400℃, 600℃, 800℃. FEM analysis was conducted to predict the life expectancy of RC structure using the property values by a series of experiment.
부산지역 레미콘사의 콘크리트의 압축강도와 염소이온 확산계수
박동천 ( Park Dong-cheon ),방중석 ( Bang Jung-suk ),김용로 ( Kim Yong-ro ),이태규 ( Lee Tae-gyu ) 한국건축시공학회 2017 한국건축시공학회 학술발표대회 논문집 Vol.17 No.2
The properties of concrete produced by ready mixed concrete company in Busan were tested. Because the concrete was mixed with blast furnace slag and fly ash, the compressive strength and chloride ion diffusion coefficient were lower than OPC concrete even though the specified concrete strength was same. If the durability about salt attack were satisfied, the concrete of lower specified concrete strength would be adopted to concrete mixing design.
박동천(Park Dong-Cheon),조규환(Cho Gyu-Hwan) 대한건축학회 2011 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.31 No.2(구조계)
Carbon dioxide in atmosphere causes concrete carbonation. Even though the carbon dioxide concentration of indoor is higher than that of outdoor, the micro measurement has not carried out. The concentration test was conducted in two rooms in a residential area, reading room in library, and lecture room. The measured average value was 463.1~1425.3(ppm) which is more than three times than that of outdoor at the most. Without surface finishings in FEM calculation, the depth of carbonation is up to 4(㎝).
대나무 활성탄을 이용한 친환경 시멘트계 건축마감재 개발을 위한 기초적 연구
박동천,권성현,Park, Dong-Cheon,Kwon, Sung-Hyun 대한건축학회 2011 대한건축학회논문집 Vol.27 No.3
The purpose of this study is to investigate the possibility of using the bamboo activated carbon as eco-building interior materials. A series of tests was conducted such as strength test, water absorbency test, and adsorption test of pollution materials. The properties was compared with the those of pine charcoal. The specimens were made with two admixtures various replacement ratio (0%, 5%, 10%). From the test results, bamboo activated carbon modified cement mortars have quite performance in strength and adsorption. The porosity of two admixture was also evaluated by SEM and nitrogen adsorption method.
대나무 활성탄을 이용한 친환경 시멘트계 건축마감재 개발을 위한 기초적 연구
박동천(Park Dong-Cheon),권성현(Kwon Sung-Hyun) 대한건축학회 2011 大韓建築學會論文集 : 構造系 Vol.27 No.3
The purpose of this study is to investigate the possibility of using the bamboo activated carbon as eco-building interior materials. A series of tests was conducted such as strength test, water absorbency test, and adsorption test of pollution materials. The properties was compared with the those of pine charcoal. The specimens were made with two admixtures various replacement ratio (0%, 5%, 10%). From the test results, bamboo activated carbon modified cement mortars have quite performance in strength and adsorption. The porosity of two admixture was also evaluated by SEM and nitrogen adsorption method.