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      • KCI등재

        Ultrasound and MRI Findings of Giant Cell Fibroblastoma in the Abdominal Wall: Radiologic-Pathologic Correlations

        민소윤,박선영,서진원,고성혜,이관섭 대한영상의학회 2020 대한영상의학회지 Vol.81 No.1

        Giant cell fibroblastoma (GCF) is a rare soft-tissue sarcoma of fibroblastic origin. To the best of our knowledge, only one brief description of the MRI findings of GCF exists in the pathologic literature. Herein, we report a case of histologically proven GCF in a 3-year-old boy who underwent ultrasonography and MRI of a superficial mass in the abdominal wall.

      • KCI등재

        Experience with Pediatric Kidney Transplantation, 1985-2016: A Single Regional Center Study

        민소윤,조태경,백희선,박숙현,김형기,허승,조민현 대한소아신장학회 2017 Childhood kidney diseases Vol.21 No.2

        Purpose: Kidney transplantation (KT) is an ideal treatment for pediatric patients with end-stage renal disease (ESRD). We report the clinical outcomes of pediatric ESRD patients who underwent KT in a single regional center. Methods: We retrospectively investigated the medical records of 60 pediatric patients who were diagnosed with ESRD and underwent KT in our hospital between January 1985 and June 2016. Results: A total of 60 children and adolescents (40 male, 20 female; mean age, 13.86±4.26 years) were included in this study. Six patients (10.0%) underwent KT immediately after receiving the diagnosis of ESRD, while the others underwent KT after dialysis treatment (mean period of dialysis, 368.7±4,41.8 days). The mean donor age (50 living-related [83.3%], 10 deceased [16.7%]) was 40.0±12.85 years and the male:female ratio was 1.07:1. The most common cause of ESRD was chronic glomerulonephritis. The overall survival rates at 1, 3, and 5 years after KT were 98%, 98%, and 96%, respectively, while the graft survival rates at 1, 3, and 5 years were 93%, 86%, and 68%, respectively. Children who underwent KT before 10 years of age had better monthly growth rates than those who underwent KT later than 10 years of age. Conclusions: KT is performed less frequently in children than in adults, but causes of ESRD vary and clinical outcomes after KT greatly affect the growth and development of pediatric patients. Therefore, further analysis and monitoring of clinical progression after KT in pediatric ESRD patients are necessary.

      • KCI등재

        Transient Orbitofacial Angioedema due to Intravenous Iodinated Contrast Media During Computed Tomography: CT Findings

        민소윤,김은수,이열,이관섭 대한영상의학회 2018 대한영상의학회지 Vol.78 No.1

        Orbitofacial angioedema is one of the common contrast-induced adverse reactions. The symptoms are recognized, based on the patient's clinical complaints. Based on prior research findings, there were no reports about contrast-induced orbitofacial angioedema that was confirmed on image findings. The researchers herein report on contrast-induced orbitofacial angioedema presented on enhanced computed tomography, following intravenous administration of iodine contrast media.

      • KCI등재후보

        레녹스 가스토 증후군을 가진 소아에서 Rufinamide의 효과 및 안전성

        민소윤(Soyoon Min),조태경(Taekyoung Jo),서효림(Hyorim Suh),노다은(Daeun Roh),황수경(Su-Kyeoung Hwang),이윤정(Yunjeong Lee),권순학(Soonhak Kwon) 대한소아신경학회 2017 대한소아신경학회지 Vol.25 No.2

        Purpose: Rufinamide (RFM) is known to be effective for children with Lennox-Gastaut syndrome (LGS). The aim of this study is to evaluate its efficacy and tolerability of Korean children with LGS. Methods: This is a single center, open label, retrospective study. Patients with LGS who received rufinamide as adjunctive therapy were enrolled in this study. Their baseline clinical characteristics, the percent change in the seizure frequency per 4 weeks, and adverse events were evaluated. Results: Among 32 children, 20 were males and the mean age was 11.3±6.6 years. After 1 month of rufinamide medication, the frequency of seizures was reduced by more than 50% in 31.3% of patients and 6.3% of patients had no seizures. After 6 months of rufinamide administration, patients with a 50% or less decrease in seizure frequency remained in a state of reduced seizure frequency and 3.1% of patients had no seizures. Side effects such as nausea, vomiting, anorexia, less active, somnolence, aggression, drooling were noted in 28.1% of patients. Conclusion: This study suggests that rufinamide can be considered as an effective and safe treatment option for intractable epileptic children such as LGS. 목적: 레녹스-가스토 증후군은 소아기에 발생하는 뇌전증 중 가장 심한 형태의 뇌전증성 뇌병증으로 알려져 있으며 여러 항경련 제 치료에도 불구하고 잘 조절되지 않아 난치성 뇌전증으로 분류된다. 본 연구의 목적은 레녹스-가스토 증후군 소아에서 rufina-mide의 효율성 및 내약성을 분석하고자하였다. 방법: 본 연구는 레녹스-가스토 증후군으로 진단되어 경북대학교 소아청소년과에서 진료받은 환자 중 2011년 1월 1일부터 2014년 12월 31일까지 rufinamide를 새로 처방 받은 32명을 대상으로 rufina-mide 투여 전과 투여 후 4주 간격으로 임상적 특징과 약효와 부작용에 대해 후향적으로 분석하였다. 결과: 남자는 20명 여자는 12명 이었으며 평균연령은 11.3세±6.6세 였다. Rufinamide 처방 1달 후 31.3%의 환자에서 발작 빈도가 50% 이상 감소하였으며 6.3%의 환자에서 완전히 발작이 없어진 것 을 확인하였다. 발작 빈도가 50% 이상 감소한 환자군은 처방 6달 후 에도 50% 이상 감소한 상태로 유지되었고, 6개월 후 3.1%의 환자에서 완전히 발작이 없어진 것을 확인하였다. 28.1%의 환자에서 부작용 이 나타났으며 부작용은 구역, 구토, 식욕부진, 활동도 저하, 기면, 공격성향, 타액분비 등이었다. 결론: 본 연구를 통해 레녹스-가스토 증후군과 같은 난치성 뇌전증을 가진 소아에서 rufinamide를 효과적이고 안전하게 사용할 수있다는 것을 확인하였다.

      • KCI등재

        Propionic Acidemia with Novel Mutation Presenting as Recurrent Pancreatitis in a Child

        최재영,장경미,민소윤,황수경,강빈,최병호 대한의학회 2019 Journal of Korean medical science Vol.34 No.47

        Propionic acidemia (PA) is a rare organic acidemia resulting from a deficiency of the mitochondrial enzyme propionyl-coenzyme A carboxylase. Most cases are diagnosed after the detection of metabolic abnormalities—such as hyperammonemia, metabolic acidosis, and ketosis—associated with complaints of vomiting, feeding difficulties, and hypotonia during the neonatal period. However, in rare late-onset cases, mild or vague symptoms make the diagnosis more challenging. Even though acute pancreatitis is relatively uncommon in children, it can occur in association with PA. We present the case of a 4-year-old child who was admitted owing to the complaint of recurrent pancreatitis and had not previously been diagnosed with having metabolic disease. During inpatient treatment for acute pancreatitis, convulsions occurred with concomitant hyperammonemia, metabolic acidosis, coagulopathy, and shock 1 week after the administration of total parenteral nutrition. He was diagnosed to have PA after a metabolic work-up and confirmed to have novel mutation by molecular genetic analysis. Because children with PA may have acute pancreatitis, although rare, vomiting and abdominal pain should raise a suspicion of acute pancreatitis. On the contrary, even among children who have never been diagnosed with a metabolic disease, if a child has recurrent pancreatitis, metabolic pancreatitis caused by organic acidemia should be considered.

      • KCI등재

        Clinical Characteristics of Febrile UTI First Developed Over 5 Years of Age

        노다은,서효림,민소윤,조태경,백희선,조민현 대한소아신장학회 2017 Childhood kidney diseases Vol.21 No.1

        Purpose: Febrile urinary tract infection (UTI) is one of the commonest bacterial infections in children. The purpose of this study is to investigate the clinical characteristics of the first episode of febrile UTI occurring in children over 5 years compared to those in infants younger than a year. Methods: We retrospectively reviewed the medical records of 10 patients over 5 years, having febrile UTI, and 25 controls under 1 year. Clinical characteristics including symptoms at admission, the time interval between symptom onset and hospital visit and/or diagnosis, duration of fever, urinalysis, and other laboratory and imaging test results were compared between the two groups. Results: Most patients in the control group showed only high fever at the time of presentation to the hospital. However, 60% of the case group had fever along with gastrointestinal (GI) symptoms such as abdominal and flank pain, vomiting, as well as relatively mild pyuria. The case group showed a longer duration between symptom onset and hospital visit and/or diagnosis. Conclusions: Delay in diagnosis and initiation of treatment of UTI increases the risk of permanent renal scarring and associated complications. Therefore, early diagnosis and treatment of febrile UTI is vital for very young infants, as well as children considering that febrile UTI could be an important cause of febrile illness in children over 5 years.

      • KCI등재후보

        한국 중ㆍ고등학교 흡연 예방 교육 실태 및 요구도 조사: ‘흡연 미디어 리터러시 교육’ 중심

        박선희(Park Sunhee),김정희(Kim Junghee),민소윤(Min Soyoon) 전남대학교 간호과학연구소 2019 Nursing and Health Issues(NHI) Vol.24 No.2

        Purpose: Given the substantially slow decreases in adolescent smoking rates, it is important to develop more effective strategies for preventing smoking among adolescents. Thus, we aimed to investigate the provision/participation experiences of school-based smoking prevention education (SPE) targeting adolescents and the perceived needs for school-based SPE, including smoking media literacy (SML) education. Methods: We used convenience sampling and collected data through self-report questionnaires. Our final sample included 50 teachers and 150 middle and high school students in Korea. We calculated means and frequencies to understand sample characteristics, provision/participation experiences of the SPE, need for the SPE, and SML education; we conducted a t-test, Wilcoxon-Mann-Whitney test, Chi-square test, and Fisher’s exact test to investigate differences in the provision/participation experiences of the SPE, need for the SPE, and SML education between teachers and students. Results: Teachers indicated the need for changes in SPE, whereas students were satisfied with the education. The majorities of teachers and students did not know the definition of SML. Only 8.0% of teachers provided SML education to students; only 5.4% of students were educated about SML. Teachers indicated the necessity of providing SML education to students; however, students did not think that SML education was highly necessary, although 55.8% were exposed to smoking-related media. Conclusion: Given our findings, school-based SML education should be provided to students. To do so, it is necessary to develop standardized teaching materials and training programs targeting teachers so that they can effectively provide SML education to students.

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