광범위한 석회화를 동반한 경화성 복막염:증례 보고

민선정,이일성,강익원,Min, Seon-Jeong,Lee, Il-Seong,Gang, Ik-Won 대한영상의학회 2003 대한영상의학회지 Vol.49 No.3

경화성 복막염 (sclerosing peritonitis)은 복막 투석 (continuous ambulatory peritoneal dial-ysis,CAPD)을 하고 있는 환자들에서 드물게 발생하는 합병증으로 소장의 기능장애, 복부 통증,투석 기능의 저하를 가져오며 심한 경우에는 장폐색을 일으킬 수 있다.경화성 복막염에서 드물게 석회화를 동반할 수 있으며 작은 석회화로 시작하여 광범위한 석회화로 진행될 수 있다. 저자들은 복부 단순 촬영과 컴퓨터 단층촬영 (CT)에서 광범위한 석회화를 동반한 경화성복막염의 전형적인 소견을 보인 예를 보고하고자 한다. Sclerosing peritonitis is an uncommon complication of continuous ambulatory peritoneal dialysis (CAPD) and can lead to small bowel dysfunction involving abdominal pain, progressive loss of ultrafiltration, and small intestinal obstruction. Peritoneal thickening, in which calcification can develop, often starts as a small plaque which gradually becomes larger. We report a case of CAPD-related calcifying peritonitis.

봉독약침이 흰쥐의 국소뇌혈류량 및 평균혈압에 미치는 영향

민선정 ( Seon Jeong Min ),염승룡 ( Seung Ryong Yeam ),권영달 ( Young Dal Kwon ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.3

ObjectivesThe present study was designed to investigate the effects of bee venom extract pharmacopunctureon (BVP) at 肩井 (GB21) on the changes in regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats, and further to determine the mechanisms. MethodsWe purchased rats about 300g and prepared diluted BVP with normal saline. And we injected diluted BVP to rats gradually progressed from 0.001 mg/kg to 0.1 mg/kg at corresponding region to GB21. After injection, we measured the changes in rCBF and MABP of rats. In addition, to determine the mechanisms of this changes, we did the same experiments twice more after pretreatment with indomethacin and metylene blue separately. ResultsBVP significantly increased rCBF but decreased MABP, suggesting that BVP potently may increase rCBF by dilating pial arterial diameter. Furthermore, the increase of BVP-induced rCBF and the decrease of BVP-induced MABP were significantly blocked by pretreatment with cyclooxygenase inhibitor, indomethacin (1 mg/kg, i.p.). But the increase of BVP-induced rCBF and the decrease of BVP-induced MABP were not blocked by pretreatment with guanylate cyclase inhibitor, methylene blue (0.01 mg/kg, i.p.). ConclusionsThese findings indicate that the action of BVP is mediated by cyclooxygenase. Furthermore these results suggest that BVP can increase rCBF in normal state, as well as improve the stability of rCBF in ischemic state. (J Korean Med Rehab 2013;23(3):37-44)

안분지신경을 침범한 대상포진의 한,양방 협진 치료 증례

민선정 ( Seon Jeong Min ),박민정 ( Min Jung Park ),유경곤 ( Kyung Gon You ),염승룡 ( Seung Ryong Yeam ),권영달 ( Young Dal Kwon ) 한방재활의학과학회 2012 한방재활의학과학회지 Vol.22 No.4

The purpose of this study is to report the effect of Korean medical treatment in patient with herpes zoster opthalmicus. The patient was treated by acupuncture, herbal medicine, Hwangryunheadok-tang(HuanglianFiedu-Tang) and Ginseng pharmacopuncture, and western medicine from July 25th to August 8th 2012. We measured visual analogue scale(VAS) and observed the change of herpes size through the picture using digital camera. Before this treatment, he took western medicine for 8 days from onset but there was no effect. However, when this Korean medical treatment was finished, VAS score changed from 10 to 1. Korean medical treatment was effective in herpes zoster. But in treating herpes zoster antiviral agents of western medicine might be needed in early stage. And further studies are needed to figure out the effects of Korean medical treatment on herpes zoster.

회전근개 부분파열 환자에 대한 한의학적 치료 증례보고

박민정 ( Min Jung Park ),민선정 ( Seon Jeong Min ),유경곤 ( Kyung Gon You ),염승룡 ( Seung Ryong Yeam ),권영달 ( Young Dal Kwon ),김성하 ( Sung Ha Kim ) 한방재활의학과학회 2012 한방재활의학과학회지 Vol.22 No.2

Objectives :This study was performed to report the effect of the conservative oriental medical treatment in the patient with rotator cuff partial tear. Methods :37 year old man lifting heavy package repeatedly was diagnosed with supraspinatus and subscapularis tendon partial tear on left shoulder magnetic resonance imaging(MRI). This patient underwent severe left shoulder pain and range of motion(ROM) limitation. We treated him by acupuncture, a bee venom injection, a herbal medicine, cupping and moxa treatment, physical therapy from January 28th 2011 to April 2nd 2011. Within this treatment period of time, we measured visual analogue scale(VAS), ROM and physical examination changes. Results :After these treatments, shoulder ROM and physical examination recovered signifcantly and static VAS score changed 9 to 0, kinetic VAS score changed 10 to 0.5. Conclusions :In this study, oriental medical treatment was effective in the patient with partial tear of rotator cuff. But this treatment tends to take a long time, so patients with severe pain may give up conservative treatment and choose an operation in a short period of time. Thus, if the more various case studies are reported, patients will follow conservative oriental treatment with confidence.

과체중,비만인 결손가정 소아청소년에 대한 한방 비만 치료 프로그램 적용 사례

박민정 ( Min Jung Park ),민선정 ( Seon Jeong Min ),유경곤 ( Kyung Gon You ),전규상 ( Kyu Sang Jun ),염승룡 ( Seung Ryong Yeam ),권영달 ( Young Dal Kwon ) 한방재활의학과학회 2012 한방재활의학과학회지 Vol.22 No.4

Objectives : The purpose of this study was to investigate the effect of oriental medical treatment on overweight and obese children of broken home. Methods : From July 26 to 30, 2010 and from August 2 to 6, 2010, 17 children were treated in W oriental medicine hospital. Herbal medicine, electroacupuncture, auricular acupuncture, exercise(a gym ball, a jump rope, treadmill etc.), diet therapy and cupping treatment were done daily for four nights and five days. Swimming was done 2 times during this period. Also growth and nutrition education, audio-visual education were done. We checked the change of waist circumference using measuring tape, weight and body composition by bioelectrical impedance analysis(BIA) at the first and the last date of treatment time. SPSS 12.0 ver. for Windowsⓡ was used for statistical analysis of this study. The results of treatment was expressed with mean and ± standard deviation. Results : After this treatment, the weight loss was 2.37±0.76 kg and total fat mass by BIA decreased 1.62±0.87 kg. The waist circumference was decreased 2.11±1.98 cm. Conclusions : Oriental medical treatment for obesity could be effective on overweight and obese chlidren of broken home suffered from untreated. Also, this program of oriental medicine could give proper direction of obesity management.

두통을 동반한 개방성 이관의 한의학적 치료 증례보고

김진희 ( Jin Hee Kim ),민선정 ( Seon Jeong Min ),유경곤 ( Kyung Gon You ),염승룡 ( Seung Ryong Yeam ),권영달 ( Young Dal Kwon ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.4

This study was performed to report the case of Korean medical treatment for the Patulous Eustachian tube patient with headache. The patient was treated by acupuncture, herbal medicine, bee venom injection, needle-embedding therapy, chuna therapy, release of cra-nial base and sacro-occipital therapy. Korean medical treatment was administered during 3 weeks. The improvement of clinical symptoms was evaluated by VAS (visual analogue scale) and SF-36 (36-Item Short Form Healthy Survey Instrument). After treatment, most symptoms decreased, headache VAS score changed 10 to 6 and tinnitus VAS score changed 10 to 5. Also, most SF-36 scores increased. Our study suggested that Korean medical treatments are effective in the patient with Patulous Eustachian tube. And further studies are required to identify underlying mechanism of treatment. (J Korean Med Rehab 2013;23(4):261-268)

관절강내 봉약침과 매선요법을 병행한 슬개골 재발성 탈구 증례보고

유경곤 ( Kyung Gon You ),김진희 ( Jin Hee Kim ),민선정 ( Seon Jeong Min ),염승룡 ( Seung Ryong Yeam ),권영달 ( Young Dal Kwon ),이지현 ( Ji Hyun Lee ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.4

The purpose of this study is to observe the effect of Korean medicine treatment in combi-nation with intra-articular bee venom injection and needle-embedding therapy on re-current patellar dislocation in patient. The Patient, diagnosed as recurrent patellar dis-location, was treated by Korean medicine treatment in combination with intra-articular bee venom injection and needle-embedding therapy. Visual analogue scale (VAS), knee flexion range of motion (ROM), Korean Western Ontario and Mcmaster Universities arthri-tis index (K-WOMAC) were used to measure changes during treatment. After treatment, VAS, knee flexion ROM, K-WOMAC were improved significantly. The Korean medicine treatment in combination with intra-articular bee venom injection and needle-embedding therapy was proved to be helpful to improve the symptoms of the recurrent patellar dislocation. (J Korean Med Rehab 2013;23(4):251-259)

비만도에 따른 Adiponectin, Leptin, Ghrelin과 인슐린 저항성, 심혈관 위험인자의 상호 연관성

김종엽 ( Jong Yeop Kim ),신현원 ( Hyun Won Shin ),정인경 ( In Kyung Jeong ),조성휘 ( Seong Whi Cho ),민선정 ( Seon Jeong Min ),이성진 ( Seong Jin Lee ),박철영 ( Cheol Young Park ),오기원 ( Ki Won Oh ),홍은경 ( Eun Gyoung Hong ) 대한내과학회 2005 대한내과학회지 Vol.69 No.6

목적 : 최근 지방세포가 다양한 물질을 분비하는 내분비기관의 하나로 간주되면서 이들의 생체내 기능과 역할을 규명하는 것은 비만 및 이와 관련된 대사 질환에 중요할 것으로 생각된다. 이에 저자 등은 에너지 대사에 중요한 역할을 하는 아디포넥틴, 렙틴, 그렐린의 변화를 체질량지수 또는 내장지방량 정도에 따라 관찰하고, 심혈관 위험인자 및 인슐린 저항성과 아디포넥틴, 렙틴, 그렐린 간의 상호 연관성에 대해 알아보고자 하였다. 방법 : 내과적 질환이 없는 남녀 86명(남:여=36:50, 나이 21~71세, 체질량지수:18.0~39.5 kg/㎡)을 대상으로 키, 체중, 허리둘레, 엉덩이둘레를 측정하고 공복 혈액에서 포도당, 인슐린, 인슐린 저항성(HOMA-IR), 총 콜레스테롤, 중성지방, 저밀도지단백 콜레스테롤(LDL-C), 고밀도지단백 콜레스테롤(HDL-C), 유리지방산, 아디포넥틴, 렙틴, 그렐린을 측정하였으며, 체지방 분포는 4번째와 5번째 요추 부위를 CT로 촬영한 후 총복부지방, 내장지방과 피하지방의 면적을 측정하였다. 남녀 각각 체질량지수(BMI)가 25 kg/㎡ 이상인 비만 유무에 따라, 그리고 복강지방 면적이 100 ㎡ 이상이거나 내장지방 대 피하지방의 비가 0.4 이상인 내장지방 주요군으로 나누어 HOMA-IR, 혈중 당대사 및 지질대사, 공복 혈액내 아디포넥틴, 렙틴, 그렐린을 비교하고 상호 연관성을 조사하였다. 결과 : 1) 체질량지수 25 kg/㎡를 기준으로 한 비만군에서 남자의 경우에서는 허리둘레, 총복부지방면적, 피하지방면적, 복강내 내장지방 면적, HDL-C, 유리지방산, hsCRP, 렙틴이 의미있는 차이를 보였으며, 여자의 경우에서는 허리둘레, 허리둘레 대 엉덩이 둘레의 비, 체지방률, 총복부지방면적, 피하지방면적, 복강내 내장지방 면적, hsCRP, 렙틴에서 의미있는 차이를 보였다. 2) 복강내 지방 면적을 기준으로 한 내장지방 주요군에서 남자의 경우, 체질량지수로 나눈 비만군보다 나이, 중성지방, 아디포넥틴, 그렐린에서 추가적인 의미 있는 차이를 보였다. 여자에서는 체질량지수로 나누었을때 보다 나이, 허리둘레 대 엉덩이 둘레의 비, 체지방률, 공복 혈당, 공복인슐린, 아디포넥틴에서 추가적인 의미있는 차이를 보였다. 3) 아디포넥틴, 렙틴, 그렐린과 비만, 인슐린저항성, 심혈관 위험인자들과의 상관관계를 분석한 결과 렙틴은 체질량지수, 허리둘레 대 엉덩이 둘레비, 총복부지방면적, 피하지방면적, 내장지방면적, LDL-C, 공복 인슐린, HOMA-IR과 통계적으로 유의하게 양의 상관관계를 보였다. 아디포넥틴은 체질량지수, 허리둘레 대 엉덩이 둘레비, 총복부지방면적, 내장지방면적, HOMA-IR과 유의하게 음의 상관관계를 보였고, HDL-C과는 양의 상관관계를 보였다. 그렐린은 허리둘레 대 엉덩이둘레비, 내장지방면적, 공복혈당, HOMA-IR과 유의하게 음의 상관관계를 보였고, HDL-C와는 유의하게 양의 상관관계를 보였다. 또한 렙틴과 그렐린과는 유의하게 음의 상관관계를 보였다. 지방 분포에 따라 피하지방 면적은 렙틴과 유의한 양의 상관관계가 있었고, 내방지방면적은 렙틴과는 양의 상관관계, 아디포넥틴 및 그렐린과는 유의한 음의 상관관계를 보였다. 결론 : 남녀 모두에서 체질량지수 보다 복부내장지방면적을 기준으로 구분 하였을 때 아디포넥틴, 렙틴, 그렐린 및 심혈관 위험인자가 더 뚜렷한 차이를 보였다. 또한 아디포넥틴, 렙틴, 그렐린 간의 연관성에 있어서는 렙틴과 그렐린이 서로 유의한 음의 상관관계가 있음을 사람 혈액에서는 처음으로 확인하였다. Background : Adiponectin, letin and ghrelin are considered to take part in the regulation of energy metabolism. We investigated the relationship between these adipokines and body mass index (BMI), regional adiposity, insulin resistance and cardiovascular risk factors in human. Methods : Eighty six (Male : Female = 36 : 50, Age = 21-71 year old, BMI : 18 - 39.5 kg/㎡) subjects without known medical problems participated in this study. Subjects were grouped based on BMI or visceral fat area (VFA) and gender. We measured lipid concentration, fasting glucose, fasting insulin, insulin resistance (HOMA-IR) and high sensitivity CRP (hsCRP). Body fat distribution was determined by computed tomography. Fasting serum adiponectin, leptin, and ghrelin were measured by ELISA. Results : The group of BMI over 25 kg/㎡ showed significant difference in waist circumference (WC), total fat area (TFA), subcutaneous fat area (SFA), VFA, Triglyceride (TG), hsCRP and leptin. Visceral fat dominant (VFD) group (VFA≥100 ㎠ or VFA/SFA≥0.4) showed significant difference in age, BMI, WC, TFA, SFA, free fatty acid, HOMA-IR, hsCRP, adiponectin, leptin and ghrelin. Leptin was positively correlated with BMI, waist hip ratio (WHR), TFA, VFA, SFA, low-density lipoprotein cholesterol (LDL-C), HOMA-IR and fasting insulin. Adiponectin was negatively correlated with BMI, WHR, TFA, VFA, HOMA-IR and positively correlated with High-density lipoprotein cholesterol (HDL-C). Ghrelin level was negatively correlated with WHR, VFA, fasting glucose, HOMA-IR and positively correlated with HDL-C. And leptin was negatively correlated with ghrelin. As regional adiposity, SFA was positively correlated with leptin, and VFA was negatively correlated with adiponectin and ghrelin and positively correlated with leptin. Conclusions : This study demonstrated that VFA had more significant association with lipid metabolism & adipokine secretion than BMI and leptin levels were inversely correlated with ghrelin level.(Korean J Med 69:631-641, 2005)

추나체형진단기와 단순 방사선 검사로 측정된 신체 지표들 간의 상관 분석

김창곤 ( Chang Gon Kim ),이진현 ( Jin Hyun Lee ),민선정 ( Seon Jeong Min ),김병숙 ( Byung Sook Kim ),송용선 ( Yung Sun Song ),이수경 ( Su Kyung Lee ),고연석 ( Youn Suk Ko ),이정한 ( Jung Han Lee ) 한방재활의학과학회 2014 한방재활의학과학회지 Vol.24 No.4

ObjectivesThis study analyzed the correlation between body parameters measured us-ing X-ray and Chuna posture analysis system to determine their clinical value in diagnosing and evaluating skeletomuscular diseases.MethodsX-ray and Chuna posture analysis system were performed for 105 patients to measure physical characteristics such as Interacromial angle, Pelvic obliquity angle, Structural leg length discrepancy (SLLD), Midpatella-midtalus angle (MMA) and Q-angle, Anterior head translation (AHT), Anterior superior iliac spine to posterior superior iliac spine angle (ASIS-PSIS angle), Interscapular angle, Scoliotic angle and Cobb`s angle. Statistical analysis using statistical analysis techniques and Pearson correlation coefficients was per-formed to assess the body parameters obtained by X-ray and Chuna posture analysis system.ResultsSignificant correlations were observed between the values for Interacromial an-gle, Pelvic obliquity angle, SLLD, MMA and Q-angle, AHT, ASIS-PSIS angle, Interscapular angle, Scoliotic angle and Cobb`s angle obtained by X-ray and Chuna posture analysis system. Significant correlations were also observed between right MMA and left Q-angle as well as between left MMA and right Q-angle.ConclusionsChuna posture analysis system can be used instead of X-ray measure body parameters and perform posture analysis in clinical practice. This study`s findings are expected to serve as a basis for further research on the clinical application of Chuna pos-ture analysis system. (J Korean Med Rehab 2014;24(4):177-185)

갑상성 소결절 : 초음파를 이용한 양성과 악성의 감별 Ultrasonographic Differentiation between Benign and Malignant Lesions

민선정,윤대영,최철순,임경자,문증희,서영란,박상준,윤영철,윤은주,강익원,이경규 대한초음파의학회 2004 ULTRASONOGRAPHY Vol.23 No.1