http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
베체트병으로 上焦 부위의 증상을 호소하는 환자에 대한 치험 1례
민선우,문지성,김예슬,박지윤,홍정화,정지천 대한한방내과학회 2022 大韓韓方內科學會誌 Vol.43 No.2
Objective: This case report presents the effects of traditional Korean medical treatment for a patient with symptoms of the upper burner due to Beçhet’s disease. Methods: A 42-year-old male patient was treated with traditional Korean herbal medicine (herbal formulas and patent medicines), acupuncture, and cupping therapy. Neck, ocular, and right wrist pain and xerostomia were assessed daily with a numeric rating scale (NRS) and grading assessment tool for subjective symptoms. Results: For a total of 20 days over two hospitalizations, the patient’s neck pain was relieved from NRS 4 to 1, the ocular pain from NRS 5 to 1, the right wrist pain from NRS 7 to 1, and the xerostomia from grade 8 to 1. Conclusion: These results show that Beçhet’s disease symptoms of the upper burner can be relieved with traditional Korean medical treatment, although additional well-designed studies are required to confirm these findings.
Post-Translational Regulation of the RSF1 Chromatin Remodeler under DNA Damage
민선우,최용원,윤한솔,조수진,지재훈,조혜성 한국분자세포생물학회 2018 Molecules and cells Vol.41 No.2
Chromatin remodeling factors are involved in many cellular processes such as transcription, replication, and DNA damage response by regulating chromatin structure. As one of chromatin remodeling factors, remodeling and spacing factor 1 (RSF1) is recruited at double strand break (DSB) sites and regulates ataxia telangiectasia mutated (ATM) -dependent checkpoint pathway upon DNA damage for the efficient repair. RSF1 is overexpressed in a variety of cancers, but regulation of RSF1 levels remains largely unknown. Here, we showed that protein levels of RSF1 chromatin remodeler are temporally upregulated in response to different DNA damage agents without changing the RSF1 mRNA level. In the absence of SNF2h, a binding partner of RSF1, the RSF1 protein level was significantly diminished. Intriguingly, the level of RSF1-3SA mutant lacking ATM-mediated phosphorylation sites significantly increased, and upregulation of RSF1 levels under DNA damage was not observed in cells overex-pressing ATM kinase. Furthermore, failure in the regulation of RSF1 level caused a significant reduction in DNA repair, whereas reconstitution of RSF1, but not of RSF1-3SA mutants, restored DSB repair. Our findings reveal that temporal regulation of RSF1 levels at its post-translational modification by SNF2h and ATM is essential for efficient DNA repair.
경피적관상동맥중재술을 시행한 후 발생한 흉통(胸痛)에 대한 한방치료 1례
민선우,김학겸,문지성,김예슬,박지윤,정지천,Min, Seon-woo,Kim, Hak-kyeom,Moon, Ji-seong,Kim, Ye-seul,Park, Ji-yoon,Jeong, Ji-cheon 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.2
Objectives: This case report presents the effects of Korean medical treatment in a patient with chest pain after percutaneous coronary intervention (PCI). Methods: An 80-year-old woman was treated with Korean herbal medicine, acupuncture, and cupping therapy. Chest pain, sore tongue, and headache were assessed daily using a numeric rating scale (NRS). Results: After 15 days of treatment, chest pain disappeared, as reflected by an NRS change from 9 to 0, and headache was relieved (NRS decreased from 9 to 2). On the eighth day of treatment, the sore tongue was also relieved, as reflected by an NRS change from 9 to 0. Conclusion: These results show that chest pain after PCI can be relieved with Korean medical treatment, and it is expected that major adverse cardiac events (MACEs) may be prevented with Korean medical treatment. However, additional well-designed studies are required to confirm these findings.
유야교사의 자아개념과 직무 스트레스 및 직무 만족도와의 관계
민선우(Min Sun-Woo),문혁준(Moon Hyuk-Jun) 가톨릭대학교 생활과학연구소 2004 생활과학연구논집 Vol.24 No.1
Early childhood teachers' self-concept was slightly higher than the average level and job stress was slightly lower than the average level. Their job satisfaction was slightly higher than the average level. As for relationships among early childhood teachers' self-concept, job stress and job satisfaction, self-concept was in a negative correlation with job stress but in a positive correlation with job satisfaction. Besides, job stress was in a negative correlation with job satisfaction.
중추신경계 질환자에게 이환된 난치성 딸꾹질의 한방치험 1례
문지성,민선우,김예슬,박지윤,홍정화,최동준 대한한방내과학회 2022 大韓韓方內科學會誌 Vol.43 No.2
Intractable hiccups are those which persist for more than one month and can often occur in patients with disorders of the central nervous system, such as stroke, epilepsy, or brain tumor. An 80-year-old male patient undergoing conservative hemodialysis for diabetic nephropathy, recently developed paralysis and dysphagia due to central nervous system complications including stroke and epilepsy. He was admitted to the ⃝⃝ Oriental Medicine Hospital, and treated with herbal medicine (Gyulpijugyeo-tang, Jeonssiigong-san, and Ijin-tang) and electrical acupuncture for 30 days. No side effects were observed during hospitalization. The frequency and duration of hiccups were measured daily and found to reduce, and the effect persisted during his admission. The patient took no other nervous system drugs. In conclusion, Korean medicine like gyulpijugyeo-tang and acupuncture can be effective for patients with intractable hiccups who cannot use alternative drugs or treatment, because of other complications.
쌍합탕 투약 후 수족부 저림증이 호전된 지주막하출혈 환자 증례보고
홍승철,민선우,문지성,김학겸,김영지,송주연,안립,신길조,최동준,Hong, Seungcheol,Min, Seonwoo,Moon, Jiseong,Kim, Hakkyeom,Kim, Youngji,Song, Juyeon,Ahn, Lib,Shin, Gil-cho,Choi, Dong-jun 대한중풍순환신경학회 2020 대한중풍.순환신경학회지 Vol.21 No.1
■ Objectives This case is to report the effect of Ssanghap-tang on paresthesia of a subarachnoid hemorrhage patient. ■ Methods A male Korean patient was treated with Ssanghap-tang and acupuncture, moxibustion for total 30 days. We observed limbs numbness, circumferences, other symptoms such as weakness and any adverse event. ■ Results After treatment, numeric rating scale of limb numbness was improved to 5 from 8 at admission without any adverse event. However, we could not find any significant differences on hand circumference and limb weakness. ■ Conclusion This case suggests that Ssanghap-tang and acupuncture, moxibustion therapy could be effective in improving paresthesia of subarachnoid hemorrhage patient.