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중국 덕주 지역의 구순구개열 의료 봉사 활동 보고 및 치험례 발표
이원덕,이부규,최진영,김종렬,오용석,민병일,김명진,Lee, Won-Deok,Lee, Bu-Kyu,Cho, Jin-Young,Kim, Jong-Ryul,Oh, Yong-Seok,Min, Byoung-Il,Kim, Myung-Jin 대한악안면성형재건외과학회 2009 Maxillofacial Plastic Reconstructive Surgery Vol.31 No.5
Il Woong Cleft lip and palate foundation was founded in 1968 by Professor emeritus Byoung-Il Min. Since then the foundation has operated numerous cleft lip and palate patients not only in Korea but also in under-developed countries such as Vietnam, China, and Cambodia. In December 2005, the foundation was allowed as an incorporated association by Ministry of Foreign affairs and Trade, so that it could have official status. From March 6th 2009 to March 14th 2009, we conductp,d charity cleft lip and palate operations of 23 patients in areas of Deozhou, China. Hereby we present the results of operations.
연구개(軟口蓋) 인두간(咽頭間) 폐쇄부전(閉鎖不全)(Velopharyngeal Incompetency) 환자(患者)에 있어서 발음(發音) 장애(障碍)에 관한 연구(硏究)
최진영,민병일,Choi, Jin-Young,Min, Byoung-il 대한악안면성형재건외과학회 1992 Maxillofacial Plastic Reconstructive Surgery Vol.14 No.1
The purpose of this study was to evaluate hypernasality, nasal air emission, glottal stop, articulation disorder in patients with velopharyngeal incompetency(V.P.I.) and to analyze speech improvement after pharyngoplasty. In this study 61 patients with velopharyngeal incompetency were tested, and in patents with pharyngoplasty speech problems before pharyngoplasty were compared with those after pharyngoplasty. The results obtained are as follows : 1. There are few speech problems in pronouncing the vowel sounds. 2. There are many speech problems in pronouncing the pressure sounds and few speech problems in non-pressure sounds. 3. Speech problems in patients with cleft palate are influenced not by anatomical defect but by severity of velopharyngeal incompetence after palatorrhaphy. 4. Operation methods which decrease the velopharygeal incompetence must be considered for reducing the speech problems. 5. Among the 61 cases with V.P.I. 19 cases(31%) showed nasal air emission and 24 cases(39%) showed glottal stop. 6. Pharyngoplasty is of benefit to primary precipitating components such as hypernasality, nasal air emission but of no benefit to secondary compensating component such as glottal stop. 7. There as no significant difference in speech improvement between pre-and post-pharyngoplasty(p<0.05).
하악전돌증 환자의 하악지 시상분할법에 의한 악교정 수술후 재발에 관한 연구
서병무(Byoung moo Seo),민병일(Byong Il Min) 대한구강악안면외과학회 1991 대한구강악안면외과학회지 Vol.17 No.2
In a study of 20 cases have been investigated clinically and radiologically long term results (6 months and over) of the sagittal split osteotomy technique (Obwegeser - Dal Pont 1961). The overall relapse rate was 30% but reoperation is not required. A statistical analysis of cephalometric radiographs was done and possible causes of relapse was discussed. The results were as following. 1. There are 6 cases of relapse in 20 patients (30%). 2. There are significant correlationship between amount of setback and long term horizontal relapse (p<0.01). 3. There are significant correlationship between surgical change of mandibular plane angle and long term horizontal relapse(p<0.01). 4. The direction and amount of vertical changes are irregular and there are no statistical correlationship. 5. The duration of fixation and patients age at operation are not correlated to horizontal relapse. 6. In preoperative cephalometric measurements, mandibular plane angle and gonial angle are not correlated with horizontal relapse. 7. Wire osteosynthesis is inadequate comparing rigid fixation in the aspect of positional stability.
5-Fluorouracil이 白鼠耳下腺에 미치는 影響에 關한 電子顯微鏡的硏究
金明國,金用琯,閔丙一 최신의학사 1975 最新醫學 Vol.18 No.8
A total of one hundred and forty male mice weighing 20gm were used throughout this experiment. Experimental mice were given an intramuscular injection of 5-fluorouracil 50mg per kg of body weight. Animals were sacrificed 1, 3, 5,7, 10 and 14 days after injection of the 5-fluorouracil. Since body weight and side action of the mice have shown that 5-fluorouracil effect "was most pronounced on day 5 after the last injection of 5-fluorouracil, electron microscope study was done using only those mice on day 5 of experimentation. For electron microscopy, the animals were perfused with 2% paraformaldehyde solution in 0.1M phosphate buffer under anesthesia with 3.5% chlorohydrate. The fixative was prewarmed to 36.5°C and perfusion made by an intracardiac approach using a 50m1 syringe filled with the fixative, In general approximately 100 to 150ml of the fixative was perfused in five minutes. Pieces of the parotid gland were taken out and fixed further in a mixture of 1 % paraformaldehyde and 1 % osmium tetroxide in the same buffer. Following washing and dehydration in graded ethanols, the tissues were embedded in a mixture of epoxy resin in a routine manner. Ultrathin sections were made on a LKB 8801 ultramicrotome, stained with 2% uranyl acetate and lead citrate. Observations were made in a Hitachi Hu-Ile and Hitachi HS-8 electron microscope. Electron microscope appearance of acinar cells from the 5-fluorouracil treated animals showed following changes. 1. In general, the cells appeared to be smaller, containing fewer secretory granules and less organized cytoplasmic organelles. 2. Though in most cells the basal rough endoplasmic reticulum was well-developed, there were occasional cells in which the"rough endoplasmic reticulum appeared less tightly organized. Elements of the rough endoplasmic reticulum tended to become confluent, producing.a labyrinthino appearance of the organelle. 3. Mitochondria of cell tended to be smaller, more rounded in appearance; and contained a less. electron dense matrix and fewer cristae: 4. The Golgi complex of acinar cells from 5-fluororacil treated animals showed in general a marked reduction in its degree of organization. This included a shortening of the lamellar elements which were composed of only a few stacks. 5. The number of transport vesicles also appeared reduced in comparison to that of control cells. 6. Lipid granules were occasionally-, fqund in the normal animals, but they were definitely increased in number at the base of acinar cells from 5-fluorouracil treated mice. 7. The structure of nucleoli was difficult to judge, as many of them were-large-and -presented-a normal appearance. However, there were occasional nucleoli which were very small, being comprised of a rather simple aggregates. of nucleolonema, and associated chromatin masses. Such a nucleoli resembled those that bad been seen in other antimetabolite treated cells.