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      • KCI등재
      • KCI등재

        Effect of Oriental Anti-Stress Agent(Bohyulanshintang) on the Salivary Gland of Rats under Restraint Stress

        류호경,전양현,이진용,홍정표,Ryu, Ho-Kyung,Chun, Yang-Hyun,Lee, Jin-Yong,Hong, Jung-Pyo The Korean Academy of Orofacial Pain and Oral Medi 1999 Journal of Oral Medicine and Pain Vol.24 No.3

        일상 생활에서 우리는 스트레스에 항상 노출되어 있으며, 스트레스는 생체의 신경계, 내분비계 및 면역계의 변화를 수반한 항상성의 파괴로 수많은 정신적, 육체적 질병을 야기시킨다. 특히 구강안면영역에서도 다양한 구강점막질환과 구강건조증 등을 발생시킨다. 스트레스를 제거하는 방법으로는 약물요법 및 상담, 명상요법, 종교요법 등 다양한 방법이 제시되고 있는데, 다소의 부작용이 나타나거나 꾸준히 시행하기가 쉽지 않으며 스트레스의 원인을 근본적으로 제거하기가 현실적으로 용이하지 않은 경우가 많아 스트레스에 대한 해결책에 대하여 많은 관심이 집중되고 있다. 이에 본인은 스트레스가 가해졌을 때 백서 악하선에서 관철되며 apoptosis에 대하여 세포보호작용을 하는 clusterin(SGP-2)을 이용하여 구속스트레스를 가하기에 앞서 오랫동안 경험적으로 사용되어 왔고 부작용이 적은 전통약물인 보혈안신탕을 투여하고 스트레스에 의한 타액선의 조직변화를 관찰하여 그 효과를 확인해 보고자하였다. Sprague-Dawley계 응성 백서(200-230g/bw) 33마리를 정상 대조군(3마리), 구속스트레스군(15마리) 및 보혈안신탕 투여 후 구속스트레스군(15마리)으로 나누고 이틀을 각각 구속장치에 구속한 후 0, 1, 3, 5, 7일에 회생시켜 악하선을 적출하였으며, 면역조직화학법 및 Northern Blot을 이용하여 clusterin의 변화를 관찰하였다. 그 결과는 다음과 같다. 1. 구속스트레스군의 악하선 조직에서 clusterin 단백질과 mRNA는 실험 즉일군에서만 미약하게 관찰되었으며 실험 3일과 5일 후에 핵붕괴 및 핵농축 등의 핵변화를 동반한 apoptosis가 관찰 되었다. 2. 보혈안신탕 투여 후 구속스트레스군의 악하선 조직에서 실험 5일군까지 clusterin 이 증가한 후 실험 7일군에서는 감소하였다. 3. 보혈안신탕 투여 후 구속스트레스군의 악하선 조직에서는 apoptosis가 관찰되지 않았다. 4. 보혈안신탕 투여 후 구속스트레스군의 악하선 조직에서 clusterin mRNA가 실험 전군에 걸쳐 미약하게 관찰되었다. 이상의 결과로 타액선 조직은 스트레스 단백질인 clusterin을 생산하여 세포를 보호함으로써 스트레스 상황에 적응하지만, 생리적 적용한계를 넘는 스트레스에 노출될 때는 apoptosis됨이 확인되었다. 그리고 보혈안신탕은 스트레스 상황에서 세포의 생리적 적응력을 높여 세포의 apoptosis를 억제하는 효과를 나타냄이 확인되었다. 따라서 본 연구결과는 구강건조증등의 스트레스성 타액선 질환의 병리기전을 규명하는데 도움이되리라 생각되며, 향후 항스트레스 효과를 가진 보혈안신탕등의 한약재를 임상에 적용함으로써 스트레스로 인한 신체의 병리적 변화를 다소나마 차단할 수 있을 것으로 사료된다.

      • KCI등재

        청년기 여성의 체형과 체중조절 경험에 따른 영양소 섭취량과 건강상태에 대한 비교 연구

        류호경,윤진숙 대한지역사회영양학회 2000 대한지역사회영양학회지 Vol.5 No.3

        This study was conducted to investigate how body size and weight control experience affect the nutrient intakes and the health status of adolescent females. The survey was carried out by self-questionnaires with 463 female high school and college students in Daegu. Analysis of data was done by using a t-test, and ANOVA with the SAS computer program. The average height, weight and BMI of the subjects were 161.2 cm, 53.4 kg, and 20.51 kg/$m^2$ respectively. However, 25.1% of the subjects belonged to the underweight group when we divided the subjects into 3 groups- underweight, normal-weight, overweight-according to their present body size. The average Fe intake of the subjects was less than 50% of the Korean recommended dietary allowances. The dietary intakes of energy and Vit. A were significantly higher in the underweight group than in other groups. However, no significant differences among body size groups were observed in the dietary habit score and the nutritional knowledge score. It also appeared that the dietary habit score and the nutritional knowledge score of the weight control attemptees were worse than those of the non-attemptees. The physical health status of the subjects significantly differed according to weight control experience, and the psychological health status of the subjects differed with present body size. The physical health condition of the weight control attemptees was worse than the non-attemptees. and the psychological health condition of the overweight group was worse than other groups. The results indicated that unnecessary weight control in adolescent females induces unhealthy food behavior which is linked to undesirable health status.

      • KCI등재

        ESTIM : 사용자 직무지식에 기반한 인터페이스 평가 지원시스템

        류호경,윤완철,Ryu, Ho-Gyeong,Yun, Wan-Cheol 대한인간공학회 1999 大韓人間工學會誌 Vol.18 No.3

        Evaluation of user interfaces has to be performed in an intuitive and subjective manner by experts especially when the problem comes to the complexity and consistency of sophisticated interface procedures. The manual analysis and evaluation of logical interfaces also tends to be slow and laborious. To make the evaluation more formal and objective, the criteria and the procedure with which the evaluation can proceed must be explicitly prescribed. Furthermore, to make the formal procedure as practical as subjective expert evaluation, the criteria must reflect the user knowledge of the target tasks since the task knowledge plays the role of a basis for users to understand the interface organizations and procedures. This paper describes ESTIM, a support system for task-based evaluation of user interface, that includes the interface evaluation criteria and implies an evaluation procedure. The support system can be used either in an interactive manner by the analyst during the evaluation or in an automatic evaluation mode. It was verified that the result of automatic evaluation by ESTIM matched the results of expert evaluation fairly well.

      • KCI등재

        의학-공학의 융합 연구인 중개 연구를 통해서 본 예술-공학 융합 연구의 발전 방향

        류호경,한가람,정은주 한양대학교 우리춤연구소 2017 우리춤과 과학기술 Vol.13 No.1

        한양대학교 아트테크놀로지학과는 예술과 공학의 창의적 융합을 통하여 21세기 미래 산업의 퍼스트 무버 연구를 지향한다. 즉 한양대학교의 강점인 공학과 예술, 그리고 인간을 이해하는 심리학 분야를 융합하여 ‘Beyond Arts’와 ‘New Engineering’ 연구를 추구하고, 예술적이고 창의적인 NEWS(New Encounters on Well-known Solutions) 연구 방법론을 기반으로 하여, 예술-공학의 융합 연구를 진행한다고 제안하고 있다. 본 논문은 한양대학교 아트테크놀로지학과 연구 철학 탄생의 배경이 된 의학-공학의 융합 연구인 중개 연구를 통하여 아트테크놀로지학과의 연구 지향점 및 표준 연구방법론 개발의 배경을 설명한다. Department of arts and technology at Hanyang University aims to deliver the first-mover research for the future society and industry through transdisciplinary studies between arts and technology. Being specialized on “Beyond Arts” and “New Engineering”, we suggests an innovative research method, which is New Encounters on Well-known Solutions (NEWS). The philosophy, current research methodology, and the future direction of the department of arts and technology is described in this paper through an example of translational research between medicine, engineering and technology.

      • KCI등재

        일부 고등학생들의 비만에 대한 인식과 체중조절 경험 및 체형과의 관계

        류호경,윤진숙 대한지역사회영양학회 1998 대한지역사회영양학회지 Vol.3 No.2

        This study was conducted to investigate the relationship among pereption of obesity, experience of weight control control and satisfaction with body image in adolescence. The subjects were 221 high school students(91 boys, 130 grils), aged 16.7 years living in a rural area. To determine the perception of obesity, knowledge about obesity, belidfs about obese people, and attitudes towards obese people were measured. The results were as follows: There was high correlation between beliefs about obese people and attitudes toward obese people. When the perception of obesity was compared by sex, girls had significantly more accurate knowledge, stronger beliefs that obesity couldn't be controlled by oneself, the higher the eating disturbance score was. It also appeared that BMI was positively correlated with the positive attitude towards obese people.

      • KCI등재

        청년기 여성의 체형 인식에 대한 조사 연구 -대구지역을 중심으로-

        류호경,윤진숙 대한지역사회영양학회 1999 대한지역사회영양학회지 Vol.4 No.4

        This study was conducted to find adolescent females perception of body image. The survey was carried out by self-questionnaires with 463 female school and college students in Daegu. Analysis of data was done using t-test, and ANOVA with the SAS computer program. The average height, weight and BMI of the subjects were 161.2cm, 53.4kg and 20.51kg/$m^2$. It appeared that 33.3% of the subjects were off the normal range of body weight ; in particular 25.1% of the subjects were under weight. While the subjects’perception of their own current body image was not distorted, they were dissatisfied with their body image because they wanted a very thin figure. Subjects were divided into 3 groups -underweight, normal weight, overweight-according to their current body size. Their perceptions of ideal and desired figures differed significantly between the groups, but they thought a thinner figure than normal body image as ideal and desired body image even in overweight group. As a result, dissatisfaction of body image in the overweight group was significantly larger than the normal-weight group, and that of the normal-weight group was larger than the underweight group. Percentages of weight control attempt were 51.7% and 64.7% in the normal weight and underweight subjects, respectively. Subjects were divided into 2 groups according to their weight control experience : those who have attempted, and who have not attempted. Weight control attemptees had a higher level of dissatisfaction with their body image than non-attemptees, both because weight control attemptees were fatter, and they perceived a thinner figure as an ideal and as a desired body image thin non-attemptees. From the results of this study, we confirmed that one of reasons of excessive weight control behavior among adolescent females was distorted perception about ideal body image.

      • A Design Thinking Process with ‘Aspie’: Developing a New Intervention for People with Asperger’s Syndrome

        류호경,한가람 한양대학교 의과대학 2016 Hanyang Medical Reviews Vol.36 No.1

        People with Asperger’s syndrome (AS) have a rather different thinking style. They may cre-ate new ideas that the designer can see this awkward thinking style as the driver for devel-oping new and innovative ideas. In this paper, both ‘Aspie’ and the designer work together to make innovative ideas, by which ‘Aspie’ could find a new contributive role in communal living. An ideation workshop is composed of two different stages with several ideation me-thods. Described is an observational study of how the ideation workshop covers their defi-cits and makes them adapt to generate their different ideas. From the observation, this pa-per realizes how we start to reestablish the relationship between AS people and the society.

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