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김동현,프리텀다빠,라다깔끼,장영동,이응석,Kim, Dong-Hyeon,Thapa, Pritam,Karki, Radha,Jahng, Yurng-Dong,Lee, Eung-Seok 대한약학회 2007 약학회지 Vol.51 No.6
TRH (thyrotropin-releasing hormone) was chemically synthesized utilizing solution phase peptide chemistry for the process development of large scaled synthesis. All the synthetic steps performed in relatively mild conditions, higher yields, easier preparations, minimum racemizations, and separation and purification by recrystallizations.
6-(티에닐메칠렌)페남 설폰의 합성과 ${\beta}$-Lactamase 저해활성
김동현,프리텀다빠,라다깔끼,장영동,이응석,Kim, Dong-Hyeon,Thapa, Pritam,Karki, Radha,Jahng, Yurng-Dong,Lee, Eung-Seok 대한약학회 2007 약학회지 Vol.51 No.6
The resistance of bacteria against ${\beta}$-lactam antibiotics is mainly caused by the production of ${\beta}$-lactamase enzymes. ${\beta}$-Lactamase inhibitors are used in combination with known antibiotics to overcome the growing problem of bacterial resistance. We prepared 6-(thienylmethylene)penam sulfones for the development of potent ${\beta}$-lactamase inhibitors and evaluated their ${\beta}$-lactamase inhibitory activities.
연구논문(硏究論文)(재록(再錄)) : 의약화학 ; 2,4,6-삼치환 피리딘: 합성, 토포이소미라제 1 및 2 저해활성, 세포독성과 구조활성관계
알준바스넷 ( Arjun Basnet ),프리텀다빠 ( Pritam Thapa ),라다깔끼 ( Radha Karki ),나영화 ( Young Hwa Na ),장영동 ( Yurng Dong Jahng ),정병선 ( Byeong Seon Jeong ),정태천 ( Tae Cheon Jeong ),이종순 ( Chong Soon Lee ),이응석 ( Eung Seo 영남대학교 약품개발연구소 2007 영남대학교 약품개발연구소 연구업적집 Vol.17 No.-