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『傷寒論』 辨病診斷體系에 근거하여 回逆湯 투여 후 호전된 아토피 피부염 1례
두인선,이성준 대한상한금궤의학회 2019 대한상한금궤의학회지 Vol.11 No.1
Objective : This case report presents the effect of Hoiyeok-tang on atopic dermatitis. A patient was diagnosed with Lesser Yin disease based on Shanghanlun provisions. Methods : According to the disease pattern identification diagnostic system based on Shanghanlun provisions (DPIDS), we diagnosed the patient with Lesser Yin disease. The patient was treated with Hoiyeok-tang for 87 days. The changes in symptoms were estimated by the SCORAD index. Results : After treatment, the SCORAD Index improved from 57.3 to 33.5. The patient also body weight from 89.1 kg to 76.5 kg. Conclusions : This case study shows the effectiveness of Hoiyeok-tang on atopic Dermatitis according to DPIDS.
오미자(五味子)의 멜라닌 생성 억제와 미백효과에 관한 연구
두인선,임규상,황충연,박민철,김남권,Doo, In-Sun,Lim, Kyu-Sang,Hwang, Chung-Yeon,Park, Min-Cheol,Kim, Nam-Kwen 대한한방안이비인후피부과학회 2007 한방안이비인후피부과학회지 Vol.20 No.3
Objective : The aim of this study is to assess the effect of Schizandrae Fructus on melanin synthesis inhibition and whitening effect. Methods : We assessed inhibitory effects of Schizandrae Fructus on melanin-release from B16F10, on melanin production in B16F10, on mushroom tyrosinase activity in vitro, on tyrosinase activity in B16F10 and effect of Schizandrae Fructus on the expression tyrosinase, TRP-1, TRP-2, PKA, ERK-1 ERK-2, AKT-1, MITF in B16F10. Results and Conclusion : 1. Schizandrae Fructus inhibited melanin-release, melanin production in B16F10. 2. Schizandrae Fructus inhibited tyrosinase activity in vitro and in B16F10. 3. Schizandrae Fructus suppressed the expression of tyrosinase, TRP-1, TRP-2, PKA, ERK-2 in B16F10.
『상한론(傷寒論)』 변병진단체계(辨病診斷體系)에 근거하여 대청룡탕(大靑龍湯) 투여 후 호전된 충동 조절 장애 1례
두인선 ( In-sun Doo ),이성준 ( Sung-jun Lee ) 대한상한금궤의학회 2018 대한상한금궤의학회지 Vol.10 No.1
Objective : This case report presents the effect of Daecheongryong-tang on Impulse Control Disorder. The patient was diagnosed with Taeyang-byung based on Shanghanlun provisions. Methods : According to Shanghanlun six meridian patterns diagnostic system, we diagnosed the patient as Taeyang-byung and she has been suffering from impulse control disorder. The patient was treated with Daecheongryong-tang. And it was provided for 60 days. The changing symptom was estimated by Global Assessment of Functioning and Visual Analogue Scale. Results : After the treatment, the patient's functioning got better from 65 to 85 on GAF. And the degree of pain was reduced from 10 to 2 on VAS. Conclusions : This case study shows an effectiveness of using Daecheongryong-tang according to Diagnostic system based on Shanghanlun provisions on Impulse Control Disorder.
『상한론(傷寒論)』 변병진단체계(辨病診斷體系)에 근거하여 오령산(五笭散) 투여 후 호전된 미주신경성 실신 증례 보고 1례
두인선 ( In-sun Doo ),이성준 ( Sung-jun Lee ) 대한상한금궤의학회 2020 대한상한금궤의학회지 Vol.12 No.1
Objective: This case report presents the effect of Oryeong-san on vasovagal syncope. The patient was diagnosed with Grater Yang disease based on Shanghanlun provisions. Methods: According to the disease pattern identification diagnostic system based on Shanghanlun provisions (DPIDS), we diagnosed the patient as presenting Greater Yang disease. The patient was treated with Oryeong-san for 45 days. The change in symptoms was estimated based on VAS. Results: After treatment, the patient’s VAS score from 10 to 0 and he was completely cured. Conclusions: This case study shows the effectiveness of using Oryeong-san on vasovagal syncope according to DPIDS.
『康平傷寒論』38條의 ‘厥逆’에 대한 임상적 해석 : 大靑龍湯으로 호전된 섭식장애 2례를 통하여
최운용,두인선,이성준 대한상한금궤의학회 2023 대한상한금궤의학회지 Vol.15 No.1
Objective : We Explored the meaning of the 厥逆 in Gangpyeong-Shanghanlun through two cases. Methods : We analyzed the original form of 厥逆 and the contexts in Shanghanlun. At the same time, we analyzed 2 clinical cases treated with 大靑龍湯 (Daecheongryong-tang) according to the newly deduced definition of 厥逆. Results : 厥逆 can be interpreted as 'Being indulged and indigestive'. We analyzed the cases and found that both cases were related to eating disorder even though their chief complaints were different. We also found that 大靑龍湯 was effective for both bulimia nervosa and anorexia nervosa. Conclusions : 厥逆 is symptoms of reflux in human body such as, gastroesophageal reflux disease, as a result of concentration or indulgence. We analyzed the two cases with DSM-5 and found that the two cases also can be diagnosed with eating disorder along with the provision (38條, 大靑龍湯). We found out the possibility of correlation between eating disorder and 38條, however, more advanced clinical studies are needed in the future.
『傷寒論』 辨病診斷體系에 근거하여 葛根黃連黃芩湯 투여 후 호전된 성인, 소아 ADHD 4례
윤효중,김민환,두인선,이성준 대한상한금궤의학회 2023 대한상한금궤의학회지 Vol.15 No.1
Objectives : This study reports on the cases of four ADHD patients who treated with herbal medication based on Disease Pattern Identification Diagnostic System (DPIDS). Methods : Two children and two adults were diagnosed with ADHD according to DSM-Ⅴ, and Galgeunhwangryeonhwanggeum-tang was administered. The parents of the two children completed the Korean ADHD Rating Scale (K-ARS) before and after treatment, while the other patients used the Korean ADHD Self Rating Scale (K-ASRS). The patients' somatic symptoms and other issues were evaluated through interviews. Results : In the first case, the K-ARS scale exhibited a change from 28 to 3. The patient demonstrated improvements in attention, concentration, and social behavior, along with the elimination of self-injurious behavior. In the second case, the K-ARS scale showed a change from 41 to 9. The patient in the third case demonstrated improved chronic fatigue, increased attention, work efficiency, and enhanced social skills, leading to maintaining employment for over six months for the first time in their life after the treatments. Additionally, the patient in the fourth case demonstrated improved work concentration and relief in nocturia. Conclusions : In this study, four patients exhibited improvements in symptoms of attention deficit, hyperactivity, and impulsivity before and after herbal treatment, leading to enhanced academic and social relationships. As the patients progressed in their health restoration, symptoms related to the genitourinary system also showed improvement.