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이화영,강성윤,김경훈,김주희,류광희,민진영,박경희,박소영,성명순,이영수,양은애,지혜미,하은교,신유섭,이상민,정은희,최선희,고영일,김선태,남동호,박중원,심정연,안영민,한두희,한만용,이용원,최정희,대한천식알레르기학회 면역요법/알레르겐연구팀 대한 소아알레르기 호흡기학회 2024 Allergy Asthma & Respiratory Disease Vol.12 No.3
. Allergen immunotherapy (AIT) is a causative treatment of allergic diseases in which allergen extracts are regularly administered in a gradually escalated doses, leading to immune tolerance and consequent alleviation of allergic diseases. The need for uniform practice guidelines in AIT is continuously growing as the number of potential candidates for AIT increases and new therapeutic approaches are tried. This updated version of the Korean Academy of Asthma Allergy and Clinical Immunology recommendations for AIT, published in 2010, proposes an expert opinion by specialists in allergy, pediatrics, and otorhinolaryngology. This guideline deals with the basic knowledge of AIT, including mechanisms, clinical efficacy, allergen standardization, important allergens in Korea, and special consideration in pediatrics. The article also covers the methodological aspects of AIT, including patient selection, allergen selection, schedule and doses, follow-up care, efficacy measurements, and management of adverse reactions. Although this guideline suggests the optimal dosing schedule, an individualized approach and modifications are recommended considering the situation for each patient and clinic.
류광희,지혜미,이화영,강성윤,김경훈,김주희,박경희,박소영,성명순,이영수,양은애,민진영,하은교,이상민,이용원,정은희,최선희,고영일,김선태,남동호,박중원,심정연,안영민,한만용,최정희,신유섭,한두희,대한천식알레르기학회 면역요법/알레르겐연구팀 대한 소아알레르기 호흡기학회 2024 Allergy Asthma & Respiratory Disease Vol.12 No.3
. Allergen immunotherapy (AIT) has been used for over a century and has been demonstrated to be effective in treating patients with various allergic diseases. AIT allergens can be administered through various routes, including subcutaneous, sublingual, intralymphatic, oral, or epicutaneous routes. Sublingual immunotherapy (SLIT) has recently gained clinical interest, and it is considered an alternative treatment for allergic rhinitis (AR) and asthma. This review provides an overview of the current evidence-based studies that address the use of SLIT for treating AR, including (1) mechanisms of action, (2) appropriate patient selection for SLIT, (3) the current available SLIT products in Korea, and (4) updated information on its efficacy and safety. Finally, this guideline aims to provide the clinician with practical considerations for SLIT.
이화영,강성윤,김경훈,김주희,류광희,민진영,박경희,박소영,성명순,이영수,양은애,지혜미,하은교,신유섭,이상민,정은희,최선희,고영일,김선태,남동호,박중원,심정연,안영민,한두희,한만용,이용원,최정희,대한천식알레르기학회 면역요법/알레르겐연구팀,Hwa Young Lee,Sung-Yoon Kang,Kyunghoon Kim,Ju Hee Kim,Gwanghui Ryu,J 대한천식알레르기학회 2024 Allergy Asthma & Respiratory Disease Vol.12 No.3
Allergen immunotherapy (AIT) is a causative treatment of allergic diseases in which allergen extracts are regularly administered in a gradually escalated doses, leading to immune tolerance and consequent alleviation of allergic diseases. The need for uniform practice guidelines in AIT is continuously growing as the number of potential candidates for AIT increases and new therapeutic approaches are tried. This updated version of the Korean Academy of Asthma Allergy and Clinical Immunology recommendations for AIT, published in 2010, proposes an expert opinion by specialists in allergy, pediatrics, and otorhinolaryngology. This guideline deals with the basic knowledge of AIT, including mechanisms, clinical efficacy, allergen standardization, important allergens in Korea, and special consideration in pediatrics. The article also covers the methodological aspects of AIT, including patient selection, allergen selection, schedule and doses, follow-up care, efficacy measurements, and management of adverse reactions. Although this guideline suggests the optimal dosing schedule, an individualized approach and modifications are recommended considering the situation for each patient and clinic.
류광희,지혜미,이화영,강성윤,김경훈,김주희,박경희,박소영,성명순,이영수,양은애,민진영,하은교,이상민,이용원,정은희,최선희,고영일,김선태,남동호,박중원,심정연,안영민,한만용,최정희,신유섭,한두희,대한천식알레르기학회 면역요법/알레르겐연구팀,Gwanghui Ryu,Hye Mi Jee,Hwa Young Lee,Sung-Yoon Kang,Kyunghoon Kim,J 대한천식알레르기학회 2024 Allergy Asthma & Respiratory Disease Vol.12 No.3
Allergen immunotherapy (AIT) has been used for over a century and has been demonstrated to be effective in treating patients with various allergic diseases. AIT allergens can be administered through various routes, including subcutaneous, sublingual, intra-lymphatic, oral, or epicutaneous routes. Sublingual immunotherapy (SLIT) has recently gained clinical interest, and it is considered an alternative treatment for allergic rhinitis (AR) and asthma. This review provides an overview of the current evidence-based studies that address the use of SLIT for treating AR, including (1) mechanisms of action, (2) appropriate patient selection for SLIT, (3) the current available SLIT products in Korea, and (4) updated information on its efficacy and safety. Finally, this guideline aims to provide the clinician with practical considerations for SLIT.