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        자폐증 아동의 조기인식 요인

        남민(Min Nam) 한국언어청각임상학회 1999 Communication Sciences and Disorders Vol.4 No.-

        자폐증을 조기에 인식하고 정확하게 진단내리는 것은 치료와 향후 예후에 결정적인 요인으로 작용하며, 가족들의 적응과 대처방법 등에도 영향을 미쳐서 매우 중요하다. 이에 본 연구에서는 자폐증 아동과 정신지체 아동을 대상으로 하여 사회인구학적 특성, 가정환경, 임신 및 출산시의 문제, 자폐증의 임상양상, 발달영역별 기능수준의 비교를 통해 조기인식의 요인을 파악하고자 하였다. 부모가 아동이 문제가 있다고 처음 인식하게 된 시기, 자폐증평정척도, 산모의 늦은 나이, 저체중, 타인에 대한 인식, 사회적 놀이, 비언어적 의사소통, 상상력이 필요한 놀이, 상동적인 신체동작, 물건의 어떤 부분에 대한 지속적인 집착, 제한된 관심의 영역, 지각 영역과 대근육영역, 인지언어능력에서 의미있는 차이가 있었다. 따라서, 본 연구결과 기존 진단기준에는 어린나이의 아동에게 부적합한 임상증상 항목들이 존재한다는 것을 알게되었으며, 이 경우 별개의 진단기준이 필요하다는 것을 제안한다. The diagnosis of autism or early- onset pervasive developmental disorder in very young children is difficult for both families and clinicians. This study is to facilitate early recognition of autism by identifying sociodemographic characteristics and family environment , prenatal and perinatal factor s on mother s, and behavior characteristics that are most apparent at young ages. Social interaction, communication, restricted activities and interest s were evaluated using standard diagnostic criteria for autism. Result s suggested that the areas of lack awareness of others, social play, nonverbal communication, imaginative play, stereotyped body movement s, part s of object s and range of interest s are more prominent than young child with mental retardation. Also, birth order , age on recognition, score of childhood autism rating scale, maternal age, birth weight and part of Psycho-Educational Profile appear to detect different aspect s of characteristics in this sample. In this study, a few symptom variables may represent on conver sation skill, speech production and content . This result suggest s that different criteria of autistic symptoms are recommend on recognition of autism in early age.

      • 정상인에서의 멜라토닌 투여에 따른 행동 및 생리적 효과

        조숙행,남민,Joe, Sook-Haeng,Nam, Min 한국정신신체의학회 1997 정신신체의학 Vol.5 No.2

        Objectives : The behavioral and physiological effects following low doses and high doses of melatonin have not been fully explored. In this study the authors investigated the nature and extent of the hypnotic effects, oral temperature, blood pressure effects, performance effects and subjective feelings following the acute administration of low pharmacological oral doses of melatonin at mid-day. Methods : Thirty-five healthy young medical students were randomly assigned to receive 6mg of oral melatonin(N=11), 12mg of oral melatonin(N=12) or a placebo(N=12) in a double-blind, placebo controlled trial. Measures of the behavioral and physiological effects used in the study were Stanford Sleepiness Scale, Digit Symbol Substitution Test, Trail test and visual analogue scale for subjective feelings. Oral temperature and blood pressure were measured. The subjects were studied between 10:00 and 16:00 hours. Data were analyzed by using repeated-measures analyses of variance(ANOVA). Results: Melatonin produced statistically significant effects on oral temperature, but there were no significant effects on time and the $dose{\times}time$ interaction. There was a significant difference on oral temperature between the 12mg oral melatonin group and the placebo group at 12:00 and 16:00 hours, but no significant difference between the 12mg and the 6mg oral melatonin groups. Melatonin produced a dose-related increase in subjective sleepiness and had significant effects on time, the $dose{\times}time$ interaction. There was a significant difference on subjective sleepiness among the placebo, 6mg, 12mg oral melatonin groups at 13:00-16:00 hours. Melatonin did not produce statistically significant dose-related effects on subjective fatigue but produced significant effects on time and the $dose{\times}time$ interaction. There was a significant difference on subjective fatigue between the 12mg, the 6mg oral melatonin groups and the placebo group at 13:00 hour. Conclusions : These data indicated that acute administration of melatonin at mid-day increased subjective sleepiness and fatigue but decreased oral temperatures. These effects were shown especially in 12mg oral melatonin group.

      • KCI등재

        Mirtazapine 사용후 정좌불능증(Akathisia)을 보인 환자 3례

        이승환,남민,정영조,Lee, Seung-Hwan,Nam, Min,Chung, Young-Cho 대한생물정신의학회 2001 생물정신의학 Vol.8 No.1

        The mirtazapine is a relatively new antidepressant that has noradrenergic and specific serotonin antagonist action(NaSSAs). This has been known as one of the most safest drugs because of its few side effects. Until now, there have been only one case report that mirtazapine causes a EPS side effect(restless leg syndrome). But the peculiar mechanism of this drug makes it impossible to explain the exact reasons why the mirtazapine could induce EPS symptoms. Authors observed three cases of mirtazapine induced akathisia. We could not explain the phenomenon the other way except akathisia. So here we presents the three case of mirtazapine induced akathisia and a few possible hypothesis of this phenomenon.

      • KCI등재

        서울 거주 중.고등학교 학생의 학년별 수면 양상

        송형석,박영민,남민,김린,Song, Hyoung-Seok,Park, Young-Min,Nam, Min,Kim, Leen 대한수면의학회 2000 수면·정신생리 Vol.7 No.1

        목 적: 청소년기에는 수면양상의 많은 변화가 있다고 알려져 있으나 학업량이 많다고 알려진 한국 학생의 수면 양상은 아직 체계적으로 연구된 바 없다. 이에 저자는 전국적인 조사에 앞선 예비연구로서, 서울의 한 지역에 위치한 중학교와 고등학교를 조사하여 청소년들의 수면 양상과 학년에 따른 변화를 알아보았다. 방 법: 서울 강동구에 위치한 H 중고등학교에 재학 중인 학생들을 대상으로, 학년별로 두 반을 선택하여 남녀 각각 50명 내지 100명이 되도록 하였다. 주말을 포함하여 7일간의 수면 일지와 설문지를 작성하게 하였으며, 동시에 조사 당시 1개월 동안의 평일과 주말 평균 수면 양상을 숫자로 기록하도록 하여 771명이 연구에 포함되었다. 평일은 월요일 오전 9시부터 토요일 오전 9시까지로 하였고, 주말은 토요일 오전 9시부터 일요일 오전 9시까지로 하였으며, 일요일 오전9시부터 월요일 오전 9시까지는 따로 분석하고 그 독립성을 검증하였다. 통계학적 분석은 SPSS/PC for windows 7.0을 이용하였다. 본 연구의 유의수준은 p<0.01로 설정하였다. 결 과: 중학교 1학년부터 고등학교 3학년까지 평일의 취침 시간은 2327에서 0131로 늦어졌고, 평일의 기상 시간은 0714에서 0639로 빨라졌으며, 평일의 수면 시간은 7.73시간에서 5.10시간으로 감소하였다. 6개 학년에서 주말에 평일보다 평균 1.60시간 많이 잤으며, 고등학교 2학년과 3학년에서 그 정도가 더 심하였다. 주말의 취침 시간은 중학교 1학년부터 고등학교 3학년까지 2324에서 0129로 늦어졌다. 수면 효율과 수면 잠복기는 비교적 학년 별로 일정한 편이었다. 남녀 간에 큰 차이는 없는 것으로 나타났으나, 여학생의 경우 남학생에 비해 평일에 10분을 더 자고 16분 정도 일찍 자는 것으로 나타났으며, 전체 수면양에서 시기적으로 여학생은 중학교 3학년에서 고등학교 1학년 사이에서, 남학생은 고등학교 1학년과 2학년 사이에서 의미 있게 감소하는 차이를 보였다. 나이가 적을수록 응답률이 낮았다. 결 론: 외국의 연구에서 보고된 결과와 비교해 보면, 대상 청소년들은 적게 자고, 늦게 자고, 일찍 일어나는 것으로 보이며, 따라서 외국의 청소년에 비해 수면 양상이 더 불량하고, 보다 많은 수면 결핍을 경험하는 것으로 보인다. 이를 제도적으로 보완하기 위한 시책이 요구된다는 점에서 향후 광범위한 추가적 연구가 필요할 것으로 사료된다. 중학교 1학년과 2학년의 어린 청소년의 경우 응답률이 낮은 것은 설문지의 형식을 제대로 이해 못한 것으로 추정되며 향후 연구에서 좀 더 통제가 필요할 것으로 생각되었다. Objectives: It is been reported that sleep patterns change significantly during the adolescent years. In Korea, the sleep patterns of adolescents have not been investigated systematically. The authors performed preliminary study about sleep patterns of middle and high school students in Seoul before nationwide study. Methods: The authors selected one of middle and high schools located in typical middle class area in Seoul. The study was performed during the periods when examination or vacation did not affect the sleep cycle. Fifty to one hundred male and female students were selected from one school year each. One of investigators explained the purposes and methods of this study to the students and gave additional explanation to the teachers in charge. We designed a questionnaire for subjects to describe the nap time, bedtime, sleep latency, total sleep time, rise time and sleep efficiency, and the students recorded sleep logs for seven days including weekend. Eight hundred three students answered the questionnaires. Among them, we selected the subjects who recorded sleep logs at least three days and filled up the questionnaires completely. Finally, seven hundred seventy one subjects were included in this study. Weekend was defined as the time from Saturday morning to Sunday morning, and Sunday sleep patterns were treated separately. Results: Across the six school years, school-night bedtimes were delayed one hundred twenty four minutes and school-ight rise times were advanced by thirty five minutes. School-night total sleep times were decreased by one hundred fifty eight minutes, and weekend bedtimes were delayed by one hundred twenty five minutes. The students tended to oversleep on weekends, and the mean of weekend oversleep was ninety six minutes. But, bedtime in weekends was not delayed. Daytime sleep, sleep latency and sleep efficiency were not changed greatly across six school years. Total sleep time of female students was decreased significantly between third middle school year and first high school year, but time of male students was decreased between first and second high school year. Conclusion: It is supposed that sleep deficiency of middle and high school students in Seoul was due to delayed bedtimes and advanced rise times across the school years.

      • KCI등재

        한국 성인에서 간접흡연노출과 우울증상 간의 상관관계

        진선권,한규만,남민,장지순,Jin, Sunkwon,Han, Kyu-Man,Nam, Min,Chang, Jisoon 대한생물정신의학회 2020 생물정신의학 Vol.27 No.2

        Objectives The aim of this study is to investigate the association between secondhand smoke (SHS) exposure and depressive symptoms among Korean adults. This study also explored the mediating role of self-rated health (SRH) and perceived usual stress (PUS) in the association between depressive symptoms, suicidal ideation and SHS exposure. Methods Data from the Korea National Health and Nutrition Examination Surveys (KNHANES) in 2014 and 2016 was analyzed for 10539 participants aged 19 years or older. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated in the logistic regression analysis with adjustment for the potential confounding factors. We also adopted the mediation analysis method by Hayes and Preacher. Results After adjusting for the potential confounding factors, SHS at home and at public places were associated with depressive symptoms and suicidal ideation among non-smokers. After adjusting for the potential confounding factors, SHS at home and at public places was associated with depressive symptoms and suicidal ideation among non-smokers. Meanwhile SHS at workplaces was associated with depressive symptoms among former smokers and with suicidal ideation among current smokers. There was an additive effect of SHS on depressive symptoms only among non-smokers. SRH mediated the association between SHS and depressive symptoms and suicidal ideation among non-smokers. We did not observe any significant mediating effect of SRH nor PUS on the association between SHS and depressive symptoms among former and current smokers. Conclusions SHS may be associated with depressive symptoms and suicidal ideation in Korean adults. Our study elucidated how SHS interacted with depressive symptoms among non-smokers through the mediation by SRH.

      • KCI등재후보

        한국 범불안장애 환자의 자율신경심장기능

        추정숙,이승환,김현,이강준,남민,정영조,Choo, Chung-Sook,Lee, Seung-Hwan,Kim, Hyun,Lee, Kang-Joon,Nam, Min,Chung, Young-Cho 대한생물정신의학회 2005 생물정신의학 Vol.12 No.1

        Objective:The purposes of this study were to investigate heart rate variability(HRV) in patients with generalized anxiety disorder(GAD) compared with major depressive disorder in Korea. Methods:Fifty-six GAD patients(20 male and 36 female) was classified into their comorbid psychiatric illness. Among them, Twenty-five patients(10 male and 15 female) who do not have any psychiatric comorbidity were compared with 30 major depressive disorder patients(12 male and 18 female). Clinical symptoms, HRV and MMPI were analysed between two group. Results:Comorbid psychiatric illnesses of GAD were ranked into no diagnosis(44.6%), MDD(32.1%), panic disorder(10.7%), social phobia(5.3%), PTSD(1.7%), OCD(1.7%), MDD+panic disorder(1.7%) and MDD+specific phobia(1.7%). GAD patients showed low functioning in HRV, but degree of decreasing HRV is not so severe compared with MDD patient. Balance of sympathetic and parasympathetic nerve tone is more severely impaired in GAD patients compared with MDD patient. The score of MMPI did not reveal any differences between two groups. Conclusions:The result showed that HRV can differenciate GAD and MDD patients. GAD patients could show decreased HRV functioning, less than MDD patients. But autonomic imbalance could be more severe in GAD than MDD patients.

      • KCI등재
      • KCI등재

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