반회후두신경 손상을 동반하지 않은 갑상선 절제술 환자에서 수술 초기의 음성 및 연하 기능의 변화에 대한 분석

김희진,금보람,김근희,전승식,김혜진,김성균,홍석진,홍석민,김용복,박일석,Kim, Heejin,Keum, Bo-Ram,Kim, Geun Hee,Jeon, Seung Sik,Kim, Hyejeen,Kim, Sung Kyun,Hong, Seok Jin,Hong, Seok-Min,Kim, Yong-Bok,Park, Il-Seok 대한후두음성언어의학회 2016 대한후두음성언어의학회지 Vol.27 No.2

Background and Objectives : After thyroidectomy, many patients experience problems report such things as reduced voice range and vocal fatigue, swallowing problems without superior and recurrent laryngeal nerve injury. The purpose of this study was to evaluate voice and swallowing problems before and after thyroid surgery without laryngeal nerve injury. Materials and Methods : Ninety-three patients who underwent thyroidectomy without laryngeal nerve injury and completed the follow-up evaluations were studied between June 2013 and December 2015. Each evaluation was performed preoperatively, as well as 1 week, 1 month postoperatively. Analysis was performed including voice handicap index (VHI), dysphagia handicap index (DHI), and acoustic voice analysis. Results : Patients show significant variation of parameters in the fundamental frequency (F), maximal phonation time (MPT), shimmer, jitter and soft phonation index (SPI) early after operation, and most of them showed recovery of parameters after 1month of operation. Perceptive complaint of voice and swallowing also showed significant decreased after operation (p<0.005). After 1month of operation, MPT, highest frequency and frequency ranges still showed significant decreased parameters. Comparing acoustic and perceptive parameters of total thyroidectomy and lobectomy, there was no significant changes between them except highest frequency (p=0.042). Conclusion : The results from both subjective and objective evaluations show voice and swallowing disturbance after thyroidectomy even in the absence of laryngeal nerve and provide patients information about the recovery process after surgery. Highest frequency parameter showed most significant changes after operation.

간 전이 암 환자의 18F-FDG PET 기반 종양 영역 정의: 영상 인자와 자동 영상 분할 기법 간의 관계분석

김희진,박승우,정해조,김미숙,유형준,지영훈,이철영,김금배,Kim, Heejin,Park, Seungwoo,Jung, Haijo,Kim, Mi-Sook,Yoo, Hyung Jun,Ji, Young Hoon,Yi, Chul-Young,Kim, Kum Bae 한국의학물리학회 2013 의학물리 Vol.24 No.2

The surgical resection was occurred mainly in liver metastasis before the development of radiation therapy techniques. Recently, Radiation therapy is increased gradually due to the development of radiation dose delivery techniques. 18F-FDG PET image showed better sensitivity and specificity in liver metastasis detection. This image modality is important in the radiation treatment with planning CT for tumor delineation. In this study, we applied automatic image segmentation methods on PET image of liver metastasis and examined the impact of image factors on these methods. We selected the patients who were received the radiation therapy and 18F-FDG PET/CT in Korea Cancer Center Hospital from 2009 to 2012. Then, three kinds of image segmentation methods had been applied; The relative threshold method, the Gradient method and the region growing method. Based on these results, we performed statistical analysis in two directions. 1. comparison of GTV and image segmentation results. 2. performance of regression analysis for relation between image factor affecting image segmentation techniques. The mean volume of GTV was $60.9{\pm}65.9$ cc and the $GTV_{40%}$ was $22.43{\pm}35.27$ cc, and the $GTV_{50%}$ was $10.11{\pm}17.92$ cc, the $GTV_{RG}$ was $32.89{\pm}36.8$4 cc, the $GTV_{GD}$ was $30.34{\pm}35.77$ cc, respectively. The most similar segmentation method with the GTV result was the region growing method. For the quantitative analysis of the image factors which influenced on the region growing method, we used the standardized coefficient ${\beta}$, factors affecting the region growing method show GTV, $TumorSUV_{MAX/MIN}$, $SUV_{max}$, TBR in order. The result of the region growing (automatic segmentation) method showed the most similar result with the CT based GTV and the region growing method was affected by image factors. If we define the tumor volume by the auto image segmentation method which reflect the PET image parameters, more accurate and consistent tumor contouring can be done. And we can irradiate the optimized radiation dose to the cancer, ultimately.

그래핀/구리폼과 그래파이트 하이브리드 구조체의 열전도 특성 연구

김희진,김형근,김예나,이우성,윤대호,양우석,Kim, Hee Jin,Kim, Hyeungkeun,Kim, Yena,Lee, Woo Sung,Yoon, Dae Ho,Yang, Woo Seok 한국결정성장학회 2013 한국결정성장학회지 Vol.23 No.5

Pure-carbon materials such as graphite, graphene, carbon nanotubes, and diamond have very high thermal conductivities. The reported thermal conductivity of graphene is in the range 3000~5000W/m-K at room temperature. Here, we developed graphene/cu foam hybrid type heat spreader to obtain higher thermal conductivity than Cu foam. Hybrid materials were characterized using optical microscopy (OM), scanning electron microscopy (SEM) and thermal conductivity measurement system; LFA (Laser Flash Analysis @ LFA 447, NETZSCH). We suggest that excellent thermal properties of graphene/cu foam hybrid structures are beneficial for all proposed electrical applications and can lead to a thermal management application.

성인으로부터 분리된 Lactobacillus casei CU2604의 우유배지에서의 생장 특성 및 생리적 특성

김희진,최재경,이경민,임중현,엄석진,김근배,Kim, Hee-Jin,Choi, Jae-Kyoung,Lee, Kyung-Min,Im, Jung-Hyun,Eom, Seok-Jin,Kim, Geun-Bae 한국축산식품학회 2009 한국축산식품학회지 Vol.29 No.5

이 연구는 성인분변으로부터 발효유 제조에 이용되는 probiotic로서의 우수한 능력을 지닌 균주를 선발하는데 목적을 두었으며 선택배지에서의 성장, 그람 양성, 현미경 관찰을 통해서 간균인 총 204개의 sample 중에서 10% skim milk에서 24시간 배양 후 커드 형성 여부에 따라 19개를 선발하였고, 2차 계대하여 48시간 후에 커드 형성 여부를 통해 6개를 선발하였다. 그 중에서 산 생성 능력이 우수한 균주를 3개 선발하여 원유로부터 분리한 L. casei MCL과 L. casei YIT 9029의 특성을 비교하였다. 선발된 균주는 그람 양성이고, 간균이며, 당 발효 실험과 16S rDNA 분석결과 Lactobacillus casei로 판명되어 L. casei CU2604, L. casei CU3204, L. casei LC8로 명명하였다. 이중 L. casei YIT 9029과 동일한 당 발효패턴을 보인 L. casei CU2604는 pH 변화와 생균수의 변화가 L. casei YIT 9029와 비슷한 양상을 보이고 PFGE 패턴이 같았다. 그러나 세포벽 지방산조성 분석결과를 통하여 L. casei YIT 9029와는 다른 균주임을 알 수 있었으며, 담즙내성, pH내성은 더 우수한 결과를 보였고, 또한 L. casei CU2604는 병원성균에 대하여 우수한 생육억제 능력을 나타내었다. 이러한 결과를 토대로 L. casei CU2604는 상업용 균주에 못지 않은 스타터로서의 특징을 가지고 있는 것으로 판단되며, 이 균주의 probiotics 특성에 대한 추가적인 연구가 진행 중에 있다.

확산성수소량에 미치는 대기조건의 영향

김희진,Kim Hee-Jin 대한용접접합학회 2005 대한용접·접합학회지 Vol.23 No.2

동물복지를 고려한 점등시간이 육계 병아리의 성장 능력 및 혈액 성상에 미치는 영향

김희진,손지선,전진주,김현수,강환구,이우도,윤연서,홍의철,Kim, Hee-Jin,Son, Jiseon,Jeon, Jin-Joo,Kim, Hyun-Soo,Kang, Hwan-Ku,Lee, Woo-Do,Yun, Yeon-Seo,Hong, Eui-Chul 한국가금학회 2022 한국가금학회지 Vol.49 No.3

This study was conducted to investigate the effect of three different photoperiods on growth performance, blood properties, and stress indicators in broiler chicks between 1-7 days after hatching. Two hundred and fifty-two 1-day-old male broiler chicks (57.0±0.12 g) were divided into three treatments, with 4 replicates per treatment and 22 birds per replicate subjected to three different photoperiods of 24L, 22L/2D and 18L/6D. A light-emitting diode bulb served as the light source, with an illuminance of 30 lx. As an experimental diet, a commercial feed based on a corn-soybean meal, with 22% CP and 3,150 kcal/kg ME diet, and water were fed ad libitum. Body weight gain, feed conversion ratio, and liver weight ratio showed a statistically significant difference between the 18L/6D and 24L treatments (P<0.05), but with no significant difference between the 22L/2D treatment and either the 24L or 18L/6D treatment. The breast meat ratio was 5.59% in the 18L/6D treatment group, which was lower than that of other treatment groups (P<0.05). The triglyceride levels were highest (P<0.05) in the 18L/6D treatment among treatments, but alanine aminotransferase levels were significantly higher (P<0.05) in the 22L/2D treatment than in the 24L treatment. Levels of cytokines, i.e., Interleukin-6 and Tumor Necrosis Factor-α did not show a significant difference among the treatments, but corticosterone content was significantly higher (P<0.05) in the 24L treatment than in the 18L/6D treatment. In conclusion, 22 hours of lighting is appropriate between 1~7 days after hatching, considering growth performance and the overall health of broiler chicks.

공공 방송·영상 아카이브 연구 프랑스 INA 사례분석을 중심으로

김희진,이경용,Kim, Hee jin,Yi, Kyoung Yong 한국기록학회 2021 기록학연구 Vol.- No.70

Broadcasting and audiovisuals are the easiest audiovisuals to access in everyday life and are shared through the media by recording the times. Overseas, independent broadcasting and audiovisual archives are already in operation under the legal system. As the domestic broadcasting and audiovisual industries continue to grow in size and are drawing global attention, the establishment and operation of public broadcasting and audiovisual archives need to be discussed in more detail. In particular, it is clear that the legal device is a task that must be preceded as the basis for the establishment of public broadcasting and audiovisual archives. To this end, this study first looked at the Digital Archive Center, which was operated in the 2000s. In addition, the cause of the dismantling of the Digital Archive Center was considered as the absence of a legal device, and the case of the Institut national de l'audiovisuel(INA), which has been operating on a legal basis for a long time, was investigated. INA is a representative example of implementing a lead-based system in the broadcasting and audiovisual fields, and has been introduced several times through previous studies, but tends to be focused on user services. Therefore, in this study, the analysis was focused on legal factors supporting the operation of INA. Finally, in order to realize the Public Broadcasting and Audiovisual Archive discussed in the previous study, I would like to suggest a legal device for the establishment of Public Broadcasting and Audiovisual Archive in Korea.

C-arm 방사선 투영법을 이용한 식도 점막 하 이물 제거

김희진,김효상,차원재,성명훈,하정훈,Kim, Heejin,Kim, Hyo-Sang,Cha, Wonjae,Sung, Myung-Whun,Hah, J. Hun 대한기관식도과학회 2013 大韓氣管食道科學會誌 Vol.19 No.1

Esophageal foreign body is common condition for visit emergency room, and most of them were successfully removed with endoscopy. However, in case of esophageal foreign body impaction, it can be difficult to localize the foreign body. We report a 29-year old man with esophageal foreign body impaction. We successfully localized and removed the esophageal submucosal foreign body using rigid endoscopy under C-arm guidance, avoiding more invasive procedure. The patient was followed up without any complication.

단지형 건물군 내 태양광 패널의 사후 평가를 통한 발전 효율 연구 - S대학의 연간 발전 실적을 중심으로 -

김희진,정혜진,Kim, Heejin,Jung, Hyejin 한국건설관리학회 2017 한국건설관리학회 논문집 Vol.18 No.5

The purpose of this study is to analyze the efficiency of PV according to installation condition in the complex type buildings. For this purpose, annual performance of solar power generation in a certain area was investigated and various methods were conducted including post operation evaluation. In addition, we tried to find out influencing factors that affect the efficiency and sought to identify their relative impact of degree through the data analysis and site visits together. In the middle of this process we can draw up major considerations for the efficient photovoltaic power generation installation. In the mean while, previous studies are making something new related with method for efficiency enhancement and individual influential factors based on experimental environment rather than the empirical data site based. As a result of the study, it was confirmed that even if installed in the same area, the power generation efficiency is 1.5 times as high as the installation condition. Furthermore, statistical analyses were performed on azimuth, tilted angle and shade, which are variables affecting conversion efficiency, and it was statistically confirmed that all variables are meaningful factors that affect the conversion efficiency which is a dependent variable. The most influential factor is the azimuth, followed by the tilted angle and the shade factor. From this result, we expect to be able to provide installation guidelines for the solar power generation equipments on the rooftop zone.

측두하악관절의 골관절염 치료에서 Avocado/Soybean Unsaponifiables의 효용성

김희진,박준상,고명연,안용우,Kim, Hee-Jin,Park, June-Sang,Ko, Myung-Yun,Ahn, Yong-Woo 대한안면통증구강내과학회 2006 Journal of Oral Medicine and Pain Vol.31 No.2

The aim of this study was to investigate the beneficial effect of a daily dose of 300 mg of ASU taken for more than 3 months on the subjects diagnosed as osteoarthritis of temporomandibular joint by RDC/TMD. Total 68 outpatients(15-54y) of female except menopause in Orofacial Pain Clinics of the Pusan National University Hospital were randomly assigned to either an ASU group(n=36) or a placebo group(n=32). The pain, noise and limited mouth opening(LOM) were evaluated by numerical analogue scale(NAS, range 0-10) and maximum comfortable opening(MCO) were measured by milimeter scale. The difference of simple uptake rate(SUR) on bone scan, hot spot(HS) on coronal SPECT, condylar bony changes on CT between the ASU and placebo groups were compared to investigate the objective effect. The obtained results were as follows. 1. Comparison of the NAS of pain, noise, LOM and MCO before treatment and 3, 6 and 9 months after treatment showed no significant difference between the ASU and placebo groups. 2. Comparison of the NAS of pain, noise, LOM and MCO before treatment and 3, 6 and 9 months after treatment showed no significant difference between the ASU and placebo groups without splint treatment, but showed more increased MCO in the ASU group than the placebo group with splint treatment at 6, 9 months after treatment. 3. Comparison of the NAS of pain before treatment and 3, 6 and 9 months after treatment that the NAS of pain at first visit divided into two groups(above or below 6) showed more decreased the NAS of pain in the ASU group than the placebo group that the NAS of pain at first visit was above 6. 4. Comparison of the NAS of pain, noise, LOM and MCO during 6 months period showed improvement of clinical symptoms within group, but no significant difference between subjects. 5. The simple uptake ratio(SUR) on bone scan and hot spot(HS) on coronal SPECT showed more increased SUR and HS in affected side than non-affected side of the ASU and placebo groups. 6. Comparing of condylar bony changes, osseous remodeling were observed highest, osteophyte lowest in the affected and non-affected side of the two groups. After treatment, comparison of condylar bony changes were observed more decreased erosive features in the ASU group than the placebo group.