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골관절염 환자에서 관절내 Sodium Hyaluronate(Hyruan®)의 투여가 슬관절통에 미치는 영향
김훈정,임경준,위상우,정종달,유벙식,안태훈,소금영 조선대학교 2000 The Medical Journal of Chosun University Vol.25 No.2
Background : Sodium Hyaluronate has been found to be deficient in the synovial fluid of patients with osteoarthritis. We evaluate the effect of intraarticular Sodium Hyaluronate(Hyruan®) on the knee joint pain in patients with osteoarthritis. Method : Ten patients with osteoarthritis of the knee were participated in this study. Sodium Hyaluronate was injected into knee joints weekly for 5 weeks consecutively. Clinical evaluations were performed using visual analogue scale(VAS) for pain, tenderness and swollen joint counts weekly for the first 5 weeks and at 10 weeks postinjection. Result : VAS, tenderness and swollen joint were all significantly improved from 2 weeks to 10 weeks. There was no complication, except pain on injection site in two patients. Conclusion : Intraarticular injection of Sodium Hyaluronate has been shown to be effective on the treatment of patients with osteoarthritis of the knee.
김훈정,김윤아 한국지적학회 2020 한국지적학회지 Vol.36 No.2
In the information-oriented society of the 21st century, geopolitics based on spatial information is a way to understand pending international issues that now occur around the world and is considered as one of the most important factors in the correct identification of their causes. This study focuses on the need and importance of spatial information-based geopolitics in secondary education. This study investigates the spatial information education system both in Korea and abroad and derived several main implications. In order to obtain more accurate conclusions about the need for spatial information and geopolitics, the survey and analysis are conducted on 320 high school students regarding the need for spatial information and geopolitical education and its current status. The data gathered from this research presents the need for spatial information-based geopolitical education and an effective approach to it. The study is significant in reflecting high school students’ perception of spatial information and geopolitics. Its results are also expected to contribute to the establishment of a framework that adopts broad geopolitical perspectives and approaches through creative and convergent education to better understand our society and world. 21세기 정보화 사회에서 공간정보에 기초한 지정학은 국제적 현안을 이해하는 방식이며, 현재 전 세계에서 발생하고 있는 거의 모든 이슈에 대한 원인을 올바르게 파악하기 위하여 매우 중요한 요소 중 하나로 평가받고 있다. 본 연구는 공간정보에 기반을 둔 지정학에 대한 중등 교육 수준에서의 교육의 필요성과 중요성에 초점을 두었으며, 이를 위해 우리나라와 외국에서 수행 중인 공간정보 교육 체계와 현황에 대하여 살펴보고 주요한 시사점을 도출하였다. 또한, 공간정보와 지정학의 필요성에 대한 보다 정확한 결과를 도출하기 위하여 320명의 고등학생을 대상으로 공간정보와 지정학 교육의 현황과 필요성을 조사·분석하였으며, 이를 토대로 공간정보 교육에 기초한 지정학 교육의 필요성과 효율적인 접근 방안을 제시하였다. 이는 현재 고등학생의 공간정보와 지정학에 대한 인식을 반영하였다는 측면에서 의의가 있다. 본 연구는 창의적이며 융합적인 교육을 통하여 우리가 현재 사는 사회와 세계를 더욱 잘 이해하기 위한 폭넓은 지정학적 시야 확보의 접근 방안에 대한 기틀 마련에 기여할 수 있을 것으로 기대된다.
Ketamine 마취유도시 Esmolol 지속적 정주가 기관내삽관에 의한 심박수와 혈압에 미치는 영향
임경준,김훈정 대한마취과학회 1996 Korean Journal of Anesthesiology Vol.31 No.1
Background: This study was designed to evaluate the effect of continuous intravenous infusion of esmolol on the heart rate and blood pressure, after ketamine induction and endotracheal intubation. Methods: With informed consent, forty patients with ASA physical status 1 were randomly divided into two groups. Esmolol group received the continuous intravenaus infusion of esmolol (at 500 ㎍/kg/min for 1 minute as a loading dose and at 300 ㎍/kg/min until 7 minutes after endotracheal intubation as a maintenance dose) and saline group received normal saline at the same volume-rate. 2 mg/kg of ketamine and 0.15 mg/kg of vecuronium were given at 4 minutes after the test drugs. Intubation was performed at 3 minutes after the induction. The changes of blood pressure, heart rate and rate pressure product were measured at different time intervals (preinduction, preintubation, immediately after intubation and postintubation 1, 3, 5 and 7minutes). Results: In the esmolol group, the changes of systolic blood pressure, ditolic blood pressure, heart rate and rate pressure product were significantly attenuated when compared with the saline group. The changes in heart rate at preintubation and intubation were not statistically significant when compared with the baseline value within the esmolol group. Conclusions: It is concluded that the infusion of esmolol attenuated the hemodynamic changes following ketamine induction and endotracheal intubation, but it is still needed to find the dosage of esmolol.