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김효빈,김자형,이종승,홍수종,성규보,Kim, Hyo Bin,Kim, Ja Hyung,Lee, Jong Seung,Hong, Soo-Jong,Sung, Gyou Bo 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.4
Pulmonary sequestration is a rare congenital mass of nonfunctional pulmonary tissue that lacks a normal-connection with the bronchial tree or the pulmonary arteries. It is clinically asymptomatic but when it is complicated with recurrent infection, it needs to be treated. Conventionally, surgical removal was recommended, but these days we are trying new and less invasive techniques, such as arterial embolization. There were several reports about successful cases of pulmonary sequestration treated by embolization, but mostly all of them were done to newborns or infants. We report a case of a 15-year-old boy with an asymptomatic pulmonary sequestration on whom was performed coil embolization, and in the follow-up computed tomography(CT), the size of the lesion was decreased. He did not suffer severe respiratory symptoms.
김효빈,Kim, Hyo-Bin 한국재활간호학회 2005 재활간호학회지 Vol.8 No.2
Purpose: To develop a substantive theory that represents caring experience from their the spouses perceived by hemodiialysis patients. Method: Grounded theory method guided the data collection and analysis. A purposeful sample of 15 hemodiialysis patients participated from April, 2005 to September, 2005. The data were collected through in-depth interviews. All interviews were audio taped and transcribed verbatim. Constant comparative analysis were performed simultaneously. Result: The core category on caring experience from their the spouses perceived by hemodialysis patients was identified "Re-establishment for life". The process was categorized into four stage, "Escaping", "Accepting", "Enduring", "Transcending". Conclusion: This study provides a framework for the development of individualized nursing intervention to care for the hemodialysis patients.
김효빈 ( Hyo Bin Kim ),조영주 ( Young Joo Cho ),유광하 ( Kwang Ha Yoo ),김동영 ( Dong Young Kim ),김지현 ( Ji Hyun Kim ),김현정 ( Hyun Jung Kim ),박창한 ( Chang Han Park ),박화영 ( Hwa Young Park ),박흥우 ( Heung Woo Park ),이용원 대한천식알레르기학회 2012 천식 및 알레르기 Vol.32 No.1
Background: Although atopic dermatitis (AD) is a common chronic inflammatory skin disease, patients and their parents do not quite understand its characteristics. We evaluated how they were diagnosed and treated and from where they obtained information about AD. Methods: We enrolled self-reported AD patients and their parents who attended the educational program held by Seoul Atopy Asthma Education Information Center, and a questionnaire was sent to each of them. Results: Enrolled patients were 107 (male 48, female 57) and their mean age was 26.71 years. Of the 107 patients, 84% were diagnosed by physicians, 60.3% were treated by dermatologists, 11.0% were treated by pediatricians, and 28.7% were treated by physicians of Chinese medicine or patients themselves. Patients thought that the most effective treatment methods were emollient application, environmental control, food restriction and medications in decreasing order. Topical steroids were avoided by 66.7% of the patients due to a fear of their side effects. Of the 107 patients 40.2% took more than 1 bath a day and 51.5% applied emollients twice or more times a day. In addition, 66.4% of all patients were on food restriction, for 46.5% of whom food restriction was recommended by physicians. Most (98.1%) of the patients and their parents emphasized the necessity of educational programs for AD. Conclusion: Although AD must be continuously controlled and treated, AD patients and their parents did not quite understand AD and its treatment. There was a gap between the understanding of AD and its actual management methods. Therefore, we should continue to develop new educational programs in order to provide correct information about AD and its treatment. (Korean J Asthma Allergy Clin Immunol 2012;32:16-20)
IL-13 +2044G/A Polymorphism 과 소아천식의 관련성 및 그 기능 연구
김효빈 ( Hyo Bin Kim ),이소연 ( So Yeon Lee ),진현승 ( Hyun Seung Jin ),김자형 ( Ja Hyeong Kim ),김봉성 ( Bong Seong Kim ),강미진 ( Mi Jin Kang ),장성옥 ( Seong Ok Jang ),홍수종 ( Soo Jong Hong ) 대한천식알레르기학회 2006 천식 및 알레르기 Vol.26 No.4
Background: The IL-13 +2044G/A is known to be associated with increased serum total IgE levels and asthma development. Variant type of IL-13 was significantly more active than wild type in inducing CD23 expression in monocytes. Objective: We investigated the association of asthma susceptibility and asthma-related phenotypes with +2044G/A and the functional difference between wild (+2044G, R110) and variant types (+2044A, Q110). Method: We enrolled 358 atopic asthmatic, 81 non-atopic asthmatic, and 146 control children and evaluated total IgE and bronchial hyperresponsiveness. Genotypes were analyzed by PCR-RFLP method. We applied wild and variant types of IL-13 to B cells and evaluated CD23 expression by flow cytometry. Result: The group with more than one variant alleles of +2044G/A was associated with asthma development, but not with increased total IgE levels than those with wild homozygote in children with asthma. When Q110 was applied to peripheral blood B cells of normal subjects and EBV-transformed B cells from children with atopic asthma, CD23 expressions was higher than those when R110 applied. Conclusion: IL-13 +2044G/A was associated with asthma development in Korean children with asthma, but not with total IgE. In addition, Q110 enhanced CD23 expression on B cells. These findings suggest that IL-13 +2044A (Q110) polymorphism may play a role in asthma development or IgE production. (Korean J Asthma Allergy Clin Immunol 2006;26:271-276)
영유아천식 악화시 Eosinophil-derived Neurotoxin 및 Eosinophil Cationic Protein 농도와 기도벽 비후 사이의 연관성
김효빈 ( Hyo Bin Kim ),최준기 ( Jun Gi Choi ),윤운기 ( Un Ki Youn ),마영수 ( Young Soo Ma ),신보문 ( Bo Moon Shin ),김정숙 ( Joung Sook Kim ),김창근 ( Chang Keun Kim ),Rachel Fletcher 대한소아알레르기 및 호흡기학회 2007 Allergy Asthma & Respiratory Disease Vol.17 No.2