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Although the structure of carbon nanotubes is important factor characterizing its properties, it is very difficult to control the structure of carbon nanotubes (MWNTs) and to predict the range of their diameter, which is the primary factor of MWNTs' physical properties. We tried to control the diameter of MWNTsby governing the feed injection temperature of floating catalyst method. The structure of MWNTs was influenced by the phase change of ferrocene fed as the catalyst,. The carbon nanotubes were very narrow at injection temperatures close to the sublimation pt. of ferrocene, in which most MWNTs had diameters in the range of 20~30 ㎚. At injection temperatures between the boiling pt. and melting pt. of ferrocene, the diameters became larger and had broad distribution. However, at injection temperatures higher than the boiling pt., the diameters became narrow again and had very uniform distribution.
秋作馬鈴署의 多收穫에 適合한 品種과 栽植密度에 關하여 結果를 要約하면 다음과 같다. 1) 發芽 및 生育은 Irish cobbler가 Tachibana 및 Shimabala에 比하여 特히 不良하였고 Tachibana 가 良好하였다. 2) 品種別 收量差는 Irish cobbler(654kg/10a)에 比하여 Tachibana 146%, Shimabala 64% 씩 增收되었다. 3) 栽植密度 收量差는 75x30cm區(1062kg/10a)에 比하여 76x24cm區 5%, 75x18cm區 8%씩 增收되었다. On the variety suitable for high yielding of fall sowing potatoes and the density of planting, the result of experiments is summarized as follows; 1) In geimination and growing, Irish cobber is quite inferior, compared with Tachibana and Shimabala. Tachibana is superior to Shimabala. 2) In th difference of yielding quantity, 146% was increased by Tachibana and 64% by Shimabala, Compared with Irish cobbler(654kg/10a). 3) In te difference of yielding quantity by the density of planting, 5% was increased in 76x24 cm plot and 8% in 75x18cm plot, compared with 75x30cm plot(1062kg/10a).
Mugwort has been used as a Korean folk medicine in treating liver diseases acting as an analgesics, sedative, diuresis, choleretics. This study was perfomed to evaluate the effect of mugwort extracts on the changes of enzyme activities, lipid accumulation of the serum and liver, when hepatotoxicity was induced by benzo(a)pyrene. The results are as follows: 1. Mugwort water extract administration prevented the increase of serum and liver AST, ALT, LDH, γ-GTP, liver ALP activities and bilirubin content caused by B(a)P injection. 2. The increase of serum and liver ALT, LDH, γ-GTP, serum AST activities and liver bilirubin contents in B(a)P treated group were decreased by mugwort methanol extract treatment. 3. Serum and liver total cholesterol, phospholipid, triglyceride level and serum HDL-cholesterol level were increased by B(a)P treatment. After combined treatment of mugwort water and methanul extracts, these lipid content were significantly decreased. 4. The hepatotropic effect of mugwort water extract and after-treatment against B(a)P induced hepatotoxicity was superior to that of methanol extract and pretreatment.
Toluene, alcohol및 vinylester류 등을 함유하고 있는 bond를 이용하여 휘발성 물질이 생체에미치는 영향을 관찰하기 위하여 rat에 일정 농도의 bond를 일정 시간 흡입시킨 뒤 각 조직에대하여 효소의 생화학적 시험과 celluloseacetate electrophoresis를 실시하여 다음과 같은 결과를얻었다. 1. Bond 흡입은 시간이 증가함에 따라 혈청, 심장, 신장, 근육, 뇌의 ChE 활성을 억제하였으며특히 폐와 간장의 ChE활성에 가장 큰 영향을 나타내었다. 2. Bond 흡입에 의해 혈청 및 각 조직 중에서 LDH활성이 증가되었으며 특히 폐와 심장,근육에서 그 영향이 현저히 나타났다. 3. Celluloseacetate electrophoresis를 통한 각 조직의 LDH isozyme pattern에는 차이가 나타났으며 bond 흡입에 의해 band의 소멸과 선명도의 감소가 일어 났는데 특히 폐에 대한 독성이가장 현저했으며 근육에 대한 독성도 큰 것으로 나타났다. Acute poisoning with organic solvents and other volatile compou-nds now usually follows deliberate inhalation(volatile substance abuse) or inges-tion of these compounds. The effect of bond inhalation was analyzed for serum, liver, lung, brain,heart, kidney and muscle. And the observations are revealed on rat cholinesterase activity, lactatedeh-ydrogenase activity and electrophoretic pattern of lactatedehydrogenase isozyme. The results are as follows ; 1. The rat cholinesterase activity on serum, heart, muscle, kidney and brain showthe decrease by increasing of inhalation time of bond, in particular the lungand liver cholinesterase activity was greatly affected. 2. Bond inhalation brough out the lactatedehydrogenase activity increased ofthe serum and the tissues and had an important effect especially in both thelung and muscle lactatedehydrogenase activities. 3. Each tissue was found to have a characteristic distribution of lactatedehydro-genase isozymes on celluloseacetate elelctrophoresis and the development ofinhalation time is shown the disappearence and diffusion of band.
The present study was undertaken to find a protective effect of Coptis Rhizoma Extract on liver injury induced by benzo (a)pyrene in rats. This crude drug significantly suppressed the increase of several biochemical parameters such as transaminase, lactate dehydrogenase and alkaline phosphatase in serum and liver and total cholesterol. But there were little changes in elevated serum phospholipid level. The results suggested that Coptis Rhizoma prevent bezo (a)pyrene-induced hepatic injury.
The Dynamics for a two body problem including pertubations for various effect show on this paper Orbit Determination is the process of obtain values of those paramter which completely specify of an orbiting body based on a set of observations of the body. Like as Orbit Determination, the dynamics for a two body problem Including pertubations is important study at first. This paper shows pertubations effect, and this result shows it also important like as magnetic field.
우리의 생활환경중 어디에나 존재하는 강력한 간독성유발물 benzo(a)pyrene으로 유도된 간장해에 대한 울금의 예방 및 치료효과를 관찰하여 다음과 같은 결과를 얻었다. 1. 울금 추출물 급여는 B(a)P투여로 증가한 혈청 ALT 와 ALP혈청을 현저히 회복시켰으나 혈청 AST활성은 회복시키지 못하였고, 혈청LDH의 활성은 전 실험군 사이에 유의적인 변화가 없었다. 2. 간조직 및 혈청중의 지질함량 변동은 B(a)P단독투여로 인한 유의성 있는 변화에 대해 단지 혈청중의 HDL-cholesterol과 total cholesterol 함량만이 울금 추출물 투여에 의해 정상범위로 회복되었다. 3. 간조직중의 glutathione 함량은 울금 추출물 투여로 B(a)P 단독투여군에 비해 유의성 있는 회복을 보였고, 과산화지질 함량은 B(a)P 단독투여로 인해 유의성 있게 증가하였으나 울금추출물 급여가 이런 증가를 회복시키지는 못했다. This study was performed to investigate the effect of Curcumae Rhizoma extract on the hepatic detoxication when benzo(a)pyrene, a hepatotoxi-cant, was administrated. The results were as followed : 1. The markedly increased enzyme activities(ALT, ALP) were decreasedby administration the Curcumae Rhizoma extract. 2. Serum HDL-cholesterol and total cholesterol contents were normal inthe Curcumae Rhizoma extract groups. 3. Liver glutathione content were decreased by administration the CurcumaeRhizoma extract. 4. It tended that the curative effects were better than the protective effectsof the Curcumae Rhizoma extract.
This study was attempt to evaluated the effect of Bupleuri Radix extract and Scutellariae Radix extract as the hepatotropic agents. In addition, we measured the relative effectiveness of drug combined treatment in comparison to that of alone treatment. The results are as follows ; 1. Serum and liver AST, ALT activities and liver bilirubin content of B(a)P treated group were significantly increased in comparison to normal group. After administration of Bupleuri Radix extract these enzyme activity and bilirubin content were decreased. 2. Scutellariae Radix extract decreased the increase of serum and liver AST, ALT, liver LDH activities and bilirubin content in B(a)) treated group. 3. After combined treatment of Bupleuri Radix and Scutellariae Radix extract, the serum and liver AST, ALT activities and liver bilirubin content were significantly decreased in comparison to that of drug alone treatment. 4. Buplerui Radix extract prevented the leakage of serum and liver total cholesterol, serum phospholipid and triglyceride levels caused by B(a)P treatment. 5. Scutellariae Radix extract prevented the leakage of serum and liver triglyceride and liver total cholesterol levels caused by B(a)P treatment. 6. After combined treatment of Bupleuri Radix and Scutellariae Radix extract, the lipid accumulation of serum and liver was significantly decreased in comparison to that of drug alone treatment. 7. The hepatotropic effect of drug extracts against B(a)P induced hepatotoxicity was superior to combined treatment of Bupleuri and Scutellariae Radix extract and after-treatment in comparison to that of alone treatment and pretreatment.
탄소화합물의 불완전 연소 및 열분해에 의해 생성되는 다환방향족 탄화수소로 간 실질세포에서 cytochrome P_450에 의해 산화되는 간장해 물질인 benzo(a)pyrene으로 유도한 rats의간독성 발현에 미치는 택사 수침액의 예방 및 치료 효과를 실험하여 다음과 같은 결과를얻었다. 1. 택사 수침액의 투여는 B(a)P투여로 현저하게 증가된 혈청 및 간장의 AST, ALT, LDH,ALP, γ-GTP 활성을 유의성 있게 감소시켰다. 2. 택사 수침액의 투여는 B(a)P투여로 증가한 혈청 total cholesterol 함량을 감소시킬 수있었다. 3. 택사의 투여는 B(a)P에 의한 간독성 발현을 유의성 있게 감소시켰으며 그 효과는 전처리가 후처리에 비해 우수하였다. Effects of Alismatis, which is a herbal drug used frequently in theoriental prescriptions, water extract on the liver-protective activities were inves-tigated in the rats. Alismatis extract, when administered into the gastric intuba-tion, produeed liver-protective effect against benzo(a)pyrene induced liver da-mage. The results obtained from liver microsomal enzyme assay, measurement ofserum and liver alanine'asaprtate aminotransferase and lipid accumulation indi-cated that alisimatis extract showed significant liver-protective activities againstbenzo(a)pyrene poisoning.