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Cordyceps militaris 로부터 분리한 Ergosterol Peroxide 의 한국인 암세포주에 대한 항암작용
김하원(Ha Won Kim),김영호(Young Ho Kim),채흥복(Xing Fu Cai),남경숙(Kyong Suk Nam),이승정(Seung Jung Lee),안혜숙(Hye Suk An),정은호(Eun Ho Jeong),윤승현(Seung Hyun Yun),성수경(Su Kyong Sung),이성진(Sung Jin Lee),현진원(Jin Won Hyun) 한국균학회 2001 韓國菌學會誌 Vol.29 No.1
N/A
마우스 대식세포에서 스테로이드 호르몬과 세포내 Ca++ 이 타우린수송체의 활성에 미치는 영향
김하원(Ha Won Kim),안혜숙(Hye Suk An),이선민(Sun Min Lee),이은진(Eun Jin Lee),현진원(Jin Won Hyun),박건구(Kun Koo Park),박태선(Tae Sun Park),김병각(Byong Kak Kim) 한국응용약물학회 2001 Biomolecules & Therapeutics(구 응용약물학회지) Vol.9 No.1
N/A The activity of taurine transporter is affected by various extracellular stimuli such as ion, hormone and stress. To assess effects of steroid hormones and cyclosporin A (CsA) on the taurine transporter activity, murine monocytic RAW264.7 cell line was stimulated with dexamethasone (DM), triamcinolone (TA), cortisone (CS), hydrocortisone (HCS), prednisone (PSN), prednisolone (PSL) and methylprednisolone (MPSL) in the presence of 12-O-tetradecanoylphorbol-l3-acetate (TPA). Treatment of TPA on the cell line led to significant reduction of taurine transporter activity. However, in case of stimulation of the cells with steroid hormones in the presence of TPA, all of them recovered TPA-induced reduction of the taurine transporter activity. Treatment of the cells with CsA led to significant reduction of the taurine transporter activity. Ionomycin (IM) recovered the reduced taurine transporter activity by CsA, but failed in the presence of EDTA, a calcium chelating agent. These results showed that glucocorticoid hormone recovered TPA-induced reduction of taurine transporter activity and that IM recovered CsA-induced reduction of the transporter activity by increasing intracellular free Ca^(++) concentration.
자동차 전동모터 이음부 자동검사장비의 측정 메커니즘에 관한 연구
하원호(Won-Ho Ha),심한섭(Han-Sub Sim),김해지(Hae-Ji Kim) 한국기계가공학회 2022 한국기계가공학회지 Vol.21 No.12
In this study, an automatic electric motor joint inspection equipment is developed to determine good and defective motor products by directly measuring the electric motor joint of the steering system for automobiles. Subsequently, a spectrum analysis is conducted to confirm the noise and vibration characteristics of electric motor joint defects. Sound pressure, loudness, roughness, and sharpness analyses are performed, and the results show that the sound pressure, loudness, roughness, and sharpness values differ based on the type of electric motor defect. The automatic inspection equipment developed in this study verifies that the presence or absence of defects in the electric motor and the defect type can be indirectly predicted.
부산 주변 해역에 출현하는 황돔(Dentex tumifrons)의 식성
김하원 ( Ha Won KIM ),백근욱 ( Gun Wook Baeck ),박주면 ( Joo Myun Park ),허성희 ( Sung Hol Huh ) 한국어류학회 2012 韓國魚類學會誌 Vol.24 No.1
부산 연안해역에서 2004년 1월부터 12월까지 매월 1회 채집된 황돔(Dentex tumifrons) 317개체의 식성을 조사하였 다. 황돔의 표준체장(SL)은 10.2~27.8 cm 범위였다. 황돔의 위내용물을 분석한 결과 새우류(Macrura)를 주로 섭식하는 육식성어종(carnivore)이었다. 새우류 다음으로 어류(Pisces) 가 중요한 먹이생물이었다. 그 다음으로 집게류(Anomura), 단각류(Amphipoda), 게류(Brachyura), 극피동물(Echinodermata), 두족류(Cephalopoda) 순으로 섭식하였다. 그 외, 갯지 렁이류(Polychaeta), 갯가재류(Stomatopoda), 이매패류(Bivalivia), 패충류 (Ostracoda), 곤쟁이류 (Mysidacea) 등을 섭식 하였지만 그 양은 매우 적었다. 가장 작은 크기군인 10~13 cm의 크기군에서는 새우류가 가장 중요한 먹이생물로 나 타났다. 13~16 cm 크기군에서는 새우류의 비율이 감소한 반면, 집게류, 극피동물, 게류의 비율이 증가하였다. 체장이 증가함에 따라 새우류, 집게류, 극피동물, 게류의 비율이 감 소한 반면, 어류의 비율은 계속 증가하였다. 어류는 체장 25 cm 이상의 크기군에서는 위내용물의 대부분을 차지하였다. The feeding habits of yellowback seabream, Dentex tumifrons, were studied using 317 specimens collected in the coastal waters of Busan, from January to December, 2004. The size of the specimens ranged from 10.2 to 27.8 cm in standard length (SL). D. tumifrons had turned out a carnivore and opportunistic predator that consumed mainly shrimps. Fishes were next important prey items. Its diet also included anomurans, amphipods, crabs, echinodermata and cephalopods. Polychaetes, stomatopods, bivalves, ostracods, mysids and so on were minor preys. The individuals of smallest size class (10~13 cm SL) fed mainly on shrimps. In the next size class (13~16 cm SL), the proportion of shrimps decreased, whereas the consumption of anomurans, echinodermata and crabs increased. The proportion of these prey items decreased as body size increased, whereas the consumption of fishes gradually increased. Fishes accounted for almost stomach contents of larger individuals (more than 25 cm SL).
동대만 잘피밭에 서식하는 가시망둑(Pseudoblennius cottoides)의 성장과 생산량
김하원,허성회,곽석남,이인철,Kim, Ha-Won,Huh, Sung-Hoi,Kwak, Seok-Nam,Lee, In-Cheol 해양환경안전학회 2014 해양환경안전학회지 Vol.20 No.5
가시망둑(1.80~10.01 cm TL)의 성장과 생산량에 대한 연구를 동대만 잘피밭에서 2006년도에 실시하였다. 가시망둑 시료는 소형 빔트롤로 총 702개체를 채집하였다. 본 연구 결과, 가시망둑에 대한 전장(TL)의 성장식은 $TL=0.0539d^{0.9105}$, 전장과 체중의 관계식은 $W=0.0079TL^3.1103$이었다. 가시망둑의 단위면적당 밀도, 생체량, 일일생산량, 연간생산량은 각각 $0.06{\pm}0.062/m^2$, $0.10{\pm}0.144g/m^2$, $0.0005{\pm}0.0006g\;AFDW/m^2/day$, $0.1833g\;AFDW/m^2/year$이었으며, P/B의 비율은 1.813이었다. 가시망둑 생산량은 생체량의 높았던 5월과 7월 9월에 가장 높았으며(0.0029, 0.0031, $0.0019g\;AFDW/m^2/day$), 생체량이 낮았던 12월에 가장 낮았다($0.00004g\;AFDW/m^2/day$). 가시망둑의 월별 생산량의 변화에서 양의 상관관계를 보인 것은 생체량과 수온이었다. The growth and production of Pseudoblennius cottoides (1.80~10.01 cm TL) were investigated in an eelgrass bed of Dongdae Bay, Korea throughout 2006. A total 702 P. cottoides were collected with a small beam trawl. Growth in fish total length was expressed as: $TL=0.0539d^{0.9105}$. The relationships between total length body weight was estimated as $W=0.0079TL^3.1103$. The densities, biomass, daily, annual production, and P/B ratio were $0.06{\pm}0.062/m^2$, $0.10{\pm}0.144g/m^2$, $0.0005{\pm}0.0006g\;AFDW/m^2/day$, $0.1833g\;AFDW/m^2/year$, and 1.813, respectively. Monthly production of P. cottoides were greatly peak in May, July and September (0.0029, 0.0031 and $0.0019g\;AFDW/m^2/day$) when the biomass was high, and the lowest value in December (0.00004g AFDW/m^2/day) when the biomass was low. Monthly change in production of P. cottoides was positively correlated with biomass and temperature.
김하원,허성회,곽석남,Kim, Ha-Won,Huh, Sung-Hoi,Kwak, Seok-Nam The Korean Society of Marine Environment and safet 2013 海洋環境安全學會誌 Vol.19 No.1
실비늘치(6.70~5.32 cm TL)의 성장과 생산량에 대한 연구는 동대만 잘피밭에서 2006년도에 실시하였다. 실비늘치 시료는 소형 빔트롤에 의해서 총 888개체가 채집되었다. Bertalanffy 성장식을 이용하여 구한 전장의 성장식은 $L_t=24.8257(1-e^{-0.5583(t+0.4816)})$이었다. 실비늘치의 밀도, 생체량, 일일생산량, 연간생산량, 그리고 P/B ratio는 각각 $0.01{\pm}0.009/m^2$, $0.17{\pm}0.16g/m^2$, $0.00006{\pm}0.00006g$ AFDW/$m^2$/day, 0.02g AFDW/$m^2$/yr, 그리고 0.12이었다. 실비늘치 생산량의 월변화는 컸으며, 7월(0.000182g AFDW/$m^2$/day), 9월(0.000127g AFDW/$m^2$/day) 그리고 11월(0.000123g AFDW/$m^2$/day)에 높았으며, 4월과 5월(0.000003g AFDW/$m^2$/day)에 가장 낮았다. 실비늘치의 생산량의 월변화는 개체수와 생체량, 그리고 성장률과 양의 상관관계를 보였다. The growth and production of Aulichthys japonicus (6.70~15.32 cm TL) were investigated in an eelgrass bed of Dongdae Bay, Korea throughout 2006. A total 888 A. japonicus were collected with a small beam trawl. Growth in fish total length was expressed by the von Bertalanffy's growth equation as: $L_t=24.8257(1-e^{-0.5583(t+0.4816)})$. The densities, biomass, daily, annual production, and P/B ratio were $0.01{\pm}0.009/m^{-2}$, $0.17{\pm}0.16g/m^2$, $0.00006{\pm}0.00006g$ AFDW/$m^2$/day, 0.02g AFDW/$m^2$/yr, and 0.12, respectively. Monthly variation in production of A. japonicus was large; the peak occurred at July, September and November 2006 (0.000182, 0.000127 and 0.000123 g AFDW/$m^2$/day), where as the lowest value was 0.000003g AFDW/$m^2$/day at April and May 2006. Monthly change in production of A. japonicus was positive correlated with number of individuals, biomass and growth rate.