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대상포진 환자의 임상적 관찰 ( 1990 - 1994 )
김시영,조보현,김중환 ( Si Young Kim,Bo Hyun Cho,Joong Hwan Kim ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.2
Background: Herpes zoster is an important and troublesome disease. Objective. The purpose of this study was the elucidation of the epidemiological and clinical characteristics of herpes zoster through patient assessrnent. Methods. During a 5- Year period, January 1990 to December 1994, 215 patients with herpes zoster were assessed with regard to annual and monthly frequency in occurrence, age and gender incidence. Associated conditions, dermatomic distributions, the relationship of onset of pain and skin lesions, Multi-CMI test and complications were also evaluated. Results : 1. The annual freguency of herpes zoster ranged from 0.88% to 1.78% (mean 1.23%) during the 5-year period. The highest number of herpes zoster patients was observed in winter (p<0. 001) especially in January. 2. Herpes zoster was found to most frequently afflict persons aged 50-59(27.9%). 71% of the patients were over 40 years of age. 3. In 76 patients(41.8%), neuralgia occurred several days(4 days mean) before the development of skin lesions. In 92 patients(50.5%), pain and skin lesions developed simultaneously while skin lesion development occurred before the onset of pain in 14 patients(7.7%). 4. Among the patients, 42.8% had associated conditions such as diabetes mellitus, hypertension, pulmonary tuberculosis, liver diseases, peptic ulcer, hypothyroidism, pharyngitis, fracture, etc. 5. The dermatomic invclvement of herpes zoster patients having one dermatome was most frequent in thoracic dermatome ca. es(52.6%). Others included cervical(16.7%), trigeminal(11.6%), sacral(6. 0%), lumbar(4.2%), facial(0.5%). Cases having two different dermatomes constituted 8.4%. 6. The most common complication of herpes zoster was postherpetic neuralgia although instance of ophthalmologic compiications, secondary bacterial infection, scar formation, Ramsay-Hunt syndrome, keloid formation, and urinary difficulty were also documented. 7. Multi-CMI(Cell-mediated immunity) tests were done on 88 herpes zoster patients. Thirteen of them(14.8%) were found to have comparatively depressed scores. Ten of the 79 single dermatome involvement patients(12.7%) and three of the 9 two dermatome involvement patients(33.3%) exhibited similar scores. Conclusion : These results are in accordance with those of previous reports with the exception of the higher incidence ot two different dermatome involvements and seasonal variation. (Kor J Dermatol 1997;35(2): 266-272)
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서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)
김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1
Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.
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