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      • KCI등재

        다이오드 검출기를 이용한 초소형 X선관(Miniature X-ray Tube)의 반가층 측정

        김주혜,안소현,오윤진,지윤서,허장용,강창무,서현숙,이레나,Kim, Ju-Hye,An, So-Hyeon,Oh, Yoon-Jin,Ji, Yoon-Seo,Huh, Jang-Yong,Kang, Chang-Mu,Suh, Hyunsuk,Lee, Rena 한국의학물리학회 2012 의학물리 Vol.23 No.4

        X선은 방사선 진단과 치료 분야에 있어서 다양하고 광범위하게 이용되고 있으며, 최근에는 방사선 치료용 초소형 X선관이 개발되었다. 초소형 X선관은 조사 목적 부위에 직접 삽입하여 사용되므로 제작 시준기에 따라 다양한 각도로 X선 조사가 가능하고, 검사 목적 외의 환자 피폭선량을 최소화한다. 이러한 초소형 X선관의 장점을 이용해서 X선 영상을 획득하는데 적용한다면 X선 진단 분야의 새로운 장을 열 것으로 기대된다. 하지만 초소형 X선관은 본래 치료용으로 설계되었기 때문에 진단용 장비에 적합한 시준기, 필터(added filter) 등이 필요하다. 따라서 자체 제작한 시준기와 필터를 적용하여 초소형 X선관의 빔 특성이 진단용에 적합한지 평가 하였고, 이를 위해서 다이오드 검출기를 이용하여 반가층을 측정하고 측정의 가능성을 평가하였다. 본 연구에서는 Si PIN Photodiode type인 Piranha 검출기(Piranha, RTI, Sweden)를 사용하여 필터 적용 유무에 따른 초소형 X선관의 반가층을 측정하고, 알루미늄 필터를 사용한 측정을 통하여 Piranha 검출기의 반가층 측정의 정확성을 평가하였다. 측정 결과에 따르면 초소형 X선관의 반가층은 필터의 장착에 따라 약 1.9배 증가하여 진단용 방사선 발생 장치의 적합성을 확인하였다. Piranha 검출기의 반가층 자동 측정값은 필터를 미장착한 경우에 실제 반가층 측정값에 비해 50% 높게 측정되어 적용이 불가능하나, 필터를 장착한 경우에는 실제 반가층 측정값과 약 15%의 차이로 감소되었다. 따라서 진단용 필터를 적용했을 경우는 Piranha 검출기의 반가층 자동측정이 가능하여 kV-X선 특성평가를 수월하게 수행할 것으로 기대된다. The X ray has been widely used in both diagnosis and treatment. Recently, a miniature X ray tube has been developed for radiotherapy. The miniature X ray tube is directly inserted into the body irradiated, so that X rays can be guided to a target at various incident angles according to collimator geometry and, thus, minimize patient dose. If such features of the miniature X ray tube can be applied to development of X ray imaging as well as radiation treatment, it is expected to open a new chapter in the field of diagnostic X ray. However, the miniature X ray tube requires an added filter and a collimator for diagnostic purpose because it was designed for radiotherapy. Therefore, a collimator and an added filter were manufactured for the miniature X ray tube, and mounted on. In this study, we evaluated beam characteristics of the miniature X ray tube for diagnostic X ray system and accuracy of measuring the HVL. We used the Si PIN Photodiode type Piranha detector (Piranha, RTI, Sweden) and estimated the HVL of the miniature X ray tube with added filter and without added filter. Through an another measurement using Al filter, we evaluated the accuracy of the HVL obtained from a direct measurement using the automatic HVL calculation function provided by the Piranha detector. As a result, the HVL of the miniature X ray tube was increased around 1.9 times with the added filter mounted on. So we demonstrated that the HVL was suitable for diagnostic X ray system. In the case that the added filter was not mounted on, the HVL obtained from use of the automatic HVL calculation function provided by Piranha detector was 50% higher than the HVL estimated using Al filter. Therefore, the HVL automatic measurement from the Piranha detector cannot be used for the HVL calculation. However, when the added filter was mounted on, the HVL automatic measurement value using the Piranha detector was approximately 15% lower than the estimated value using Al filter. It implies that the HVL automatic measurement can be used to estimate the HVL of the miniature X ray tube with the added filter mounted on without a more complicated measurement method using Al filter. It is expected that the automatic HVL measurement provided by the Piranha detector enables to make kV-X ray characterization easier.

      • 지오텐신 전환 효소 억제제가 급성 호흡곤란 증후군에 미치는 영향

        김주혜,이진우,박영식,이창훈,임재준,유철규,김영환,한성구,이상민 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.-

        급성호흡곤란증후군은 극심한 저산소증 및 양측성 폐침윤이 특징인 임상적 증후군으로서 높은 사망률을 보여, 병태생리에 근거한 새로운 치료법의 도입이 시급하다. 초기 폐손상 후 회복되지 않고 폐섬유화가 진행하여 나쁜 예후를 보여주고 있어, 섬유화 진행을 억제하는 것이 치료의 한 목표가 될 수 있다. 한편 앤지오텐신 전환효소 억제제는 신경호르몬계에 영향을 주어 심장이나 신장 등 타조직 내 섬유화를 억제한다고 알려져 있어, 급성 호흡곤란 증후군 환자에서 앤지오텐신 전환효소 억제제 투여가 예후에 영향을 미치는지 확인하고자 하였다. 방법: 2005년 1월 이후 2006년 12월까지 서울대학교병원에서 급성호흡곤란증후군으로 진단받고 중환자실에 입실한 환자들의 의무기록을 후향적으로 분석하였다. 앤지오텐신 전환효소 억제제 혹은 앤지오텐신 수용체 차단제를 복용한 환자군과 복용하지 않은 환자군 사이에서 기계 환기 기간 및 중환자실 사망률을 비교하였다.성적: 총 53명이 분석되었고, 환자 연령의 중앙값은 63.7세이며, 남자가 43명(81.1%)였다. 중환자실입실 후 앤지오텐신 전환효소 억제제 혹은 수용체 차단제를 복용한 사람은 8명(15.1%)이었다. 복용군과 복용군간 입실 시 APACHE II score는 33.1 vs 30.1(p=0.203), SOFA score는 11.3 vs 10.4 (p=0.432)로 유의한 차이가 없었다. 기도 재삽관 시행한 경우는 각각 9명(20.0%)과 3명(37.5%) (p=0.361), ICU 재입실한 경우는 4명(8.9%)과 1명(12.5%) (p=0.574), 기계환기 기간은 18.29 vs 27.0 (p=0.147)으로 유의한 차이가 없었다. 그러나, 성향점수 보정 후 시행한 생존분석에서는 앤지오텐신 전환효소 억제제 혹은 수용체 차단제를 복용한환자군의 생존률이 높은 경향을 보였다. 결론: 급성호흡곤란증후군환자에서 앤지오텐신 전환효소 억제제 혹은 수용체 차단제 복용이 사망률 감소에 기여할 수 있을 것으로 기대된다. 한글키워드: 급성 호흡곤란 증후군, 안지오텐신 전환 효소 억제제영문키워드: acute respiratory distress syndrome

      • KCI등재

        스마트러닝을 활용한 사이버가정학습 개선 방안 연구 : 상호작용을 중심으로

        김주혜 현대영어교육학회 2013 현대영어교육 Vol.14 No.2

        As information and communication technology has developed, the educational environment has been rapidly changing from e-Learning to Smart Learning. At this turning point, Cyber Home Learning, as a national e-Learning program initiated to assist public education, needs to be changed, too. The purpose of this study is to analyze the Cyber Home Learning content and Learning Management System of elementary-level English and to identify ways to improve the Cyber Home Learning in a Smart Learning environment. The analysis focuses on the interaction types and support functions of Cyber Home Learning in the 6th grade English courses, and English teachers in elementary schools participated in a survey. The results of the analysis show that the current Cyber Home Learning program has diverse support functions for student-content interaction and student-instructor interaction. Comparatively, however, it is difficult to find enough support functions for studentstudent interactions such as personal information exchange, thematic opinion exchange, and free opinion sharing. Therefore, suggestions based on Smart Content Creation, Smart Teaching and Learning, Smart Assessment, Learning Management System, and Social Network Services were made for future directions in the development of Cyber Home Learning.

      • KCI등재

        [14C]Butachlor의 벼에 대한 흡수 및 대사

        김주혜,김종환,김대욱,김찬섭,임양빈,서종수 한국농약과학회 2015 농약과학회지 Vol.19 No.3

        In the present study, the metabolism of [14C]butachlor was investigated in rice plant according to the OECD test guideline No. 501. [14C]Butachlor was treated as granule to paddy water by application of 1.5 kg ingredient (a.i.)/ha at the 3~4 leave stage of rice plant. At 85 days after treatment (DAT), samples of panicle, foliage, and roots were taken for radioactivity analysis. Upon harvest at 126 DAT, rice plants were separated into brown rice, husk, straw, and root parts. Amounts of total radioactivity absorbed by rice plant ranged from 8.6 to 9.8% of applied radioactivity (AR). Total radioactive residues (TRRs) of rice plant at 126 DAT was the highest as 4.0421 mg/kg (7.3% AR) in the straw followed by 1.4595 mg/kg (2.4% AR) in the root, 0.7257 mg/kg (0.1% AR) in the husk. The lowest level recording 0.1020 mg/kg (0.1% AR) was found in brown rice. Each part was extracted with various solvents and solvent/water mixtures. Greater than 70% of TRRs was readily extractable from foliage, panicle, husk and straw. Only 34.0% of the brown rice and 43% of root based on TRRs were extractable showing that the residues were completely assimilated in the plant tissue. The level of non-extractable radioactivity was ranged from 26.2 to 66.0% of TRRs. From this study, five tentative major metabolites (M1, M2, M3, M4 and M5) were observed in rice extracts. Among the metabolites, 2,6-diethylaniline assigned as M4 was identified in rice plant by comparing to retention time of reference standard. Un-metabolized butachlor was not detected in any fractions. In soil extracts, N- (butoxymethyl)-N-(2,6-diethyl phenyl)acetamide, 2,6-diethylaniline, M2, M3 and M5 were observed. And the concentration of butachlor was low level (ca. 0.03 mg/kg). OECD Test guideline 501에 따라, 벼에서의 [14C]butachlor의 식물대사 시험을 실시하였다. 시험토양은 국내 논토양의 대표적인 토성인 양토였으며, 사용지침서상의 사용법에 준하여 이앙 6일 후 [14C]butachlor를 입제로 조제하여 1.5 kg/ha 수준으로 토양 수면에 처리하였다. 시료는 시험물질 처리 후 85일과 126일에 채취하였다. 85일 시료는 이삭, 벼 잎, 뿌리로 126일 후 시료는 현미, 왕겨, 볏짚, 뿌리로 분리하였다. 모든 식물 부위의 총 방사성 잔류량은 0.01 mg/kg 이상이었다. 그 후, 대사산물과 모화합물를 확인하기 위하여 극성이 다른 유기용매와 물 혼합용액을이용하여 시료를 추출 후 Radio-HPLC로 분석하였다. 벼 추출액 중 butachlor는 검출되지 않았고, 5개의 잠정적 주요대사산물(M1, M2, M3, M4 그리고 M5)이 검출되었으며, 대사산물 중 M4는 2,6-diethylanline로 동정되었다. 토양추출액에서 N-(butoxymethyl)-N-(2,6-diethyl phenyl)acetamide, 2,6-diethylaniline, M2, M3 그리고 M5가 검출되었으며 butachlor의 농도는 낮은 수준 (약 0.03 mg/kg)으로 검출되었다.

      • KCI등재

        [14C]Butachlor를 이용한 호기성 토양대사 시험법 확립

        김주혜,김종환,김대욱,이봉재,김찬섭,임양빈,서종수 한국농약과학회 2014 농약과학회지 Vol.18 No.4

        The test method of aerobic transformation in soil has established based on international test guideline (OECD TG 307). And then, the case study was conducted with [ 14 C]butachlor. Butachlor is commonly used herbicide in Korea. [ 14 C]Butachlor was treatrd 6.83 mgKg −1 in loamy soil. The treated soil was incubated in flow-through system for 60 days. The mass balance of applied radioactivity (AR) ranged from 91.1 to 95.5% and from 93.0% to 97.7% for non-sterile and sterile soils, respectively. In non-sterile soil, the concentration of [ 14 C]butachlor was declined from 94.4% AR at 0 day to 8.4% AR at 60 days after treatment. 2-Chloro-2',6'-diethylacetanilide was the major degradation product detected in soil extract. The calculated DT 50 and DT 90 of butachlor were 10.4 days and 34.6 days, respectively. 14 CO 2 and non-extractable soil residue were increased up to 3.5% and 43.5% AR at 60 DAT. There is no significant decrease of the [ 14 C]butachlor through the incubation period in sterile soil. OECD Test guideline 307 에 따라 확립한 토양대사 시험법으로 , 호기성 토양 조건에서 [ 14 C]butachlor 의 토양대사 시험을 실시하였다 . 시험토양은 국내 밭토양의 대표적인 토성인 양토였으며 , 비멸균 및 멸균토양에 [ 14 C] butachlor (6.83 mgKg − 1 ) 을 처리하고 flow-through system 에서 60 일간 배양하였다 . 시험기간 동안 mass balance 는 비멸균 토양과 멸균토양에서 각 처리방사능 대비 91.1~95.5%, 93.0~97.7% 수준이었다 . 비멸균 토양의 경우 처리 후60 일 경과 시 처리방사능의 8.4% 로 감소하였으며 , DT 50 과 DT 90 은 10.4 일과 34.6 일이었다 . 토양 추출액 중 주요대사산물 2-chloro-2',6'-diethylacetanilide 이 검출되었다 . 14 CO 2 및 비추출성 토양잔류물은 3.5% 와 43.5% 수준이었다 . 시험기간 중 멸균 토양 내 [ 14 C]butachlor 의 분해는 거의 일어나지 않았다 . 따라서 butahclor 는 호기성 토양에서 미생물에 의해 빠르게 분해되어 주요 대사산물 2-chloro-2',6'-diethylacetanilide 와 CO 2 를 생성하거나 토양에 강하게 흡착되어 비추출성 잔류물로 존재하는 것으로 판단된다 . 이를 통해 OECD guideline TG 307 에 확립한 호기성토양대사 시험법은 농약의 위해성 평가를 위한 토양 동태 예측 있어 국내 활용에 적합할 것으로 판단된다.

      • 글로벌 해상화물의 물류네트워크 패턴 연구

        김주혜,김율성,남정우 한국항해항만학회 2022 한국항해항만학회 학술대회논문집 Vol.2022 No.춘계

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

      • KCI등재

        Development of a New Metal Artifact Reduction Algorithm by Using an Edge Preserving Method for CBCT Imaging

        김주혜,남혜원,이레나 한국물리학회 2015 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.67 No.1

        CT (computed tomography) images, metal materials such as tooth supplements or surgical clips can cause metal artifact and degrade image quality. In severe cases, this may lead to misdiagnosis. In this research, we developed a new MAR (metal artifact reduction) algorithm by using an edge preserving filter and the MATLAB program (Mathworks, version R2012a). The proposed algorithm consists of 6 steps: image reconstruction from projection data, metal segmentation, forward projection, interpolation, applied edge preserving smoothing filter, and new image reconstruction. For an evaluation of the proposed algorithm, we obtained both numerical simulation data and data for a Rando phantom. In the numerical simulation data, four metal regions were added into the Shepp Logan phantom for metal artifacts. The projection data of the metal-inserted Rando phantom were obtained by using a prototype CBCT scanner manufactured by medical engineering and medical physics (MEMP) laboratory research group in medical science at Ewha Womans University. After these had been adopted the proposed algorithm was performed, and the result were compared with the original image (with metal artifact without correction) and with a corrected image based on linear interpolation. Both visual and quantitative evaluations were done. Compared with the original image with metal artifacts and with the image corrected by using linear interpolation, both the numerical and the experimental phantom data demonstrated that the proposed algorithm reduced the metal artifact. In conclusion, the evaluation in this research showed that the proposed algorithm outperformed the interpolation based MAR algorithm. If an optimization and a stability evaluation of the proposed algorithm can be performed, the developed algorithm is expected to be an effective tool for eliminating metal artifacts even in commercial CT systems.

      • KCI등재

        초등영어 교사 불안에 대한 연구

        김주혜,김성연 한국초등영어교육학회 2004 초등영어교육 Vol.10 No.1

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        Teacher anxiety is an important variable to consider with regard to English language teaching, in that it may negatively influence the way teachers make instructional decisions. This study aims to identify sources of primary school English teacher anxiety. The Foreign Language Teaching Anxiety Scale (FLTAS) was used to measure anxiety in Korean primary school English teachers. The study found that the items on which the participants displayed high levels of anxiety were directly related to primary school settings. In addition, the teachers' anxiety was found to have statistically high, negative correlation with their preferences for innovative teaching approaches, whereas the correlation between teacher anxiety and the preference for traditional approaches was high and positive. The results also provide a potential explanation of anxiety-producing contexts in foreign language classrooms, the sources of anxiety, and coping strategies that teachers use to lower their anxiety. Pedagogical implications of the findings are discussed.

      • KCI등재

        Direct Power Control of Three-Phase Boost Rectifiers by using a Sliding-Mode Scheme

        김주혜,주성탁,최대근,이교범 전력전자학회 2013 JOURNAL OF POWER ELECTRONICS Vol.13 No.6

        This paper proposes a sliding-mode-based direct power control (DPC) method in a three-phase boost rectifier without the use of a voltage sensor. This sliding-mode-based DPC is used to improve transient-state response characteristics. This DPC can eliminate voltage sensors by calculating a voltage using a sensorless method, thus considerably reducing cost. This DPC first presents an effective algorithm that does not significantly affect the previous performance and does not need a voltage sensor. Thereafter, the effectiveness of the algorithm is verified by simulations and experiments.

      • KCI등재

        고등학교 졸업학력 검정고시와 실용영어 1 교과서 지문의 언어적 요소 비교분석

        김주혜,김해동 한국중등영어교육학회 2022 중등영어교육 Vol.15 No.1

        This study aims to compare linguistic features in the texts between high school graduate equivalency tests and practical English 1 textbooks for high school students in Korea. The text data obtained from ten sets of tests from 2016 to 2020 and six English 1 textbooks were analyzed by using Coh-Metrix, a linguistic computational program. The results of the analysis on linguistic features reveal that the levels of difficulty were not consistent between two texts. The difficulty levels of the sentence length, the syntactic complexity and the readability in the tests were significantly lower than those in the textbooks. On the contrary, the difficulty levels of the lexical diversity and the cohesion in the tests were significantly higher. The findings suggest that the difficulty of texts in the test needs to be adjusted to be equivalent with that in the textbook when test designers write the test items.

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