유전자변형식물의 검정기술 개발 현황

김재환,김영록,김해영,Kim, Jae-Hwan,Kim, Young-Rok,Kim, Hae-Yeong 한국식물생명공학회 2011 식물생명공학회지 Vol.38 No.2

1994년 처음으로 GM 토마토인 Flavr Savr가 시장에 나온 이후, 2010년 현재 140여 품목의 GM식물이 전 세계적으로 상업화되었다. GM식물들에 대한 안전성 승인여부의 확인 및 표시제관리를 위하여 이들 GM식물내로 도입된 삽입유전자의 정보를 이용한 검정방법이 도입되었으며, 또한 도입유전자의 발현된 단백질을 분석하기 위하여 정성 및 정량을 위한 면역학적 방법이 도입되었다. 본 총설에서는 국내 외적으로 개발된 콩, 옥수수, 카놀라, 면화 등의 GM식물에 적용된 multiplex PCR, real-time PCR 방법과 최신 개발 중인 microarray, 나노기술 등을 활용한 방법들을 조사하였다. Since the first commercial GM plant, the FlavrSavr tomato, authorized in 1994, more than 140 GM plants were authorized for marketing globally. For the authorization and labelling of GM plants, the detection methods for genes introduced and proteins expressed in GM plants were developed qualitatively and quantitatively. This review presented the detection methods, conventional PCR, multiplex PCR and real-time PCR, for soybean, maize, canola and cotton as the dominant GM plants. Also, microarray assay and nanotechnology as new approaches for detection methods for GM plants were investigated.

망목 구조 변화에 따른 에폭시 수지의 유전 특성에 관한 연구

김재환,손인환,심종탁,김경환,김명호,최병옥 ( Jae Hwan Kim,In Hwan Son,Jong Tak Shim,Kyung Hwan Kim,Myung Ho Kim,Byung Ok Choi ) 한국전기전자재료학회 1997 전기전자재료학회논문지 Vol.10 No.7

암석 재질에 따른 보존처리제의 현장 적용성 평가

김재환,한민수,이장존,송치영,이재만,김민지,이명성,Kim, Jae-Hwan,Han, Min-Su,Lee, Jang-Jon,Song, Chi-Young,Lee, Jae-Man,Kim, Min-Ji,Lee, Myeong-Sung 국립문화재연구소 2009 保存科學硏究 Vol.30 No.-

Stone cultural heritages are mostly situated in field, so they are damaged from mechanical, chemical and biological weathering, and their degree of strength is also weaken. Therefore, the scientific conservation of the stone cultural heritages are necessary in order to the long-term maintenance and safety conservation. In this study, we attempt to estimate on the field application of consolidants which are Wacker OH 100, Remmers KSE 300 and 1T1G according to the quality of the rocks. Based on the ultrasonic velocity, conditions of weathering damage before treatment are mainly ranked completely weathering condition (CW) or partly highly weathering condition (HW). After the first treatment, weathering damage conditions are changed by the high weathering condition (HW). These results shows that the internal pores of stone are filled with consolidant materials, so average ultrasonic velocities increases after treatment. And Remmers KSE 300 which is consolidant material is highest rate of increase of average ultrasonic velocities.

천연 셀룰로오스를 이용한 MEMS 기술

김재환,Kim, Jae-Hwan 대한기계학회 2007 기계저널 Vol.47 No.10

산업부산물 레드머드를 활용한 흙포장재의 특성 및 현장적용 사례

김재환,김병기,Kim, Jae-Hwan,Kim, Byeong-Ki 한국건설순환자원학회 2017 한국건설순환자원학회지 Vol.12 No.4

결함위치추정 기법을 이용한 공대지 항공무장의 오류 요인 분석

김재환,최경희,정기현,Kim, Jae-Hwan,Choi, Kyung-Hee,Chung, Gi-Hyun 한국군사과학기술학회 2010 한국군사과학기술학회지 Vol.13 No.4

In this paper, we suggest a localization method of factors affecting the accuracy of Air-to-Ground weapon delivery. The proposed method, called FBEL(Factor-Based Error Localization), is based on the fault localization technique widely utilized in the realm of software engineering field. FBEL localizes the major factors affecting the performance of weapon delivery. To analyze the effectiveness and the applicability of FBEL, we applied FBEL to real firing data and got the major factors caused the errors. We expect that the method could contribute to improve the quality of weapon delivery system. We also expect that it may aid improvement of pilot capability greatly, if it is applied to pilot firing training.

소프트웨어 오류 추정 기법을 활용한 공대지 사격 오류 요인 분석 모델

김재환,최경희,정기현,Kim, Jae-Hwan,Choi, Kyung-Hee,Chung, Ki-Hyun 한국시뮬레이션학회 2011 한국시뮬레이션학회 논문지 Vol.20 No.3

This paper proposes a model to analyze the fault factors of air-to-ground weapon delivery utilizing software fault localization methods. In the previous study, to figure out the factors to affect the accuracy of air-to-ground weapon delivery, the FBEL (Factor-based Error Localization) method had been proposed and the fault factors were analyzed based on the method. But in the study, the correlation between weapon delivery accuracy and the fault factors could not be revealed because the firing accuracy among several factors was fixed. In this paper we propose a more precise fault analysis model driven through a study of the correlation among the fault factors of weapon delivery, and a method to estimate the possibility of faults with the limited number of test cases utilizing the model. The effectiveness of proposed method is verified through the simulation utilizing real delivery data. and weapons delivery testing in the evaluation of which element affecting the accuracy of analysis that was available to be used successfully.

가스.스팀터빈 분야 연구동향

김재환,Kim, Jae-Hwan 한국유체기계학회 2007 한국유체기계학회 논문집 Vol.10 No.1

특집 4_2009년 식품시장동향 및 2010년 전망 - 커피

김재환,Kim, Jae-Hwan 한국식품산업협회 2010 좋은식품 Vol.213 No.-

Tongue Cancer 환자에서 PET/CT 검사 시 Open Mouth 촬영법의 유용성 평가

김재환,윤종준,정지욱,김정욱,황주원,지혜인,Kim, Jae Hwan,Yun, Jong Jun,Jung, Ji Wook,Kim, Jung Wook,Hwang, Ju Won,Ji, Hye In 대한핵의학기술학회 2016 핵의학 기술 Vol.20 No.2

Purpose Tongue cancer is 1.8% of all cancer tumors occur in the tongue, it is known that the high incidence enough to account for 75% of oral cancer conducted a PET / CT examination for early diagnosis, metastasis, staging, etc. and. Tongue when PET / CT scan of a cancer patient and a Torso taken to close mouth lesions if the condition was caused due to the overlapping or corresponding artifacts are not clearly observed. The purpose of this study is to evaluate the changes that occur during PET / CT scan with open mouth and its usefulness under. Materials and Methods From June 2015 to March 2016 complained of herein by May 21 had received a diagnosis of tongue cancer underwent PET / CT scan patients were treated with a target (16 males, 5 female). The first was taken to close mouth Torso state, it was taken to add 1 bed open mouth condition. Tumor (T), measuring the Normal Tongue (NT), Lymph Node (LN) standard intake coefficient by setting a region of interest in the (standardized uptake value, SUV) SUVmean, the average value was measured SUVmax, drawn to each region of interest 3 times and Background (Carotid artery) was out of the SUV. In Chapter 3 of the slice to the tumor clearly visible by setting the region of interest to measure the change Tumor size was calculated average value. Gross Image resolution assessment were analyzed statistically through were divided into 1-5 points by the Radiation 7 people in 2, more than five years worked in specialized nuclear medicine compare to proceed with the blind test nonparametric test (wilcoxon signed rank test). (SPSS ver.18) Results $SUV_{mean}$ T's were in close mouth $5.01{\pm}2.70$ with open mouth $5.48{\pm}2.88$ (P<0.05), $SUV_{max}$ were respectively $8.78{\pm}5.55$ and $9.70{\pm}5.99$ (P<0.05). $SUV_{mean}$ in the NT were respectively $0.43{\pm}0.30$ and $0.34{\pm}0.24$ (P=0.20), $SUV_{max}$ was $0.56{\pm}0.34$ and $0.45{\pm}0.25$ (P=0.204). LN $SUV_{mean}$ were respectively $1.62{\pm}1.43$ and $1.69{\pm}1.49$ (P=0.161), $SUV_{mean}$ was $2.09{\pm}1.88$ and $1.99{\pm}1.74$ (P=0.131). Tumor size change is close mouth $4.96{\pm}4.66cm^2$ $5.33{\pm}4.64cm^2$ with 7.45% increase was (P<0.05), gross image resolution evaluation is $2.87{\pm}0.73$, $3.77{\pm}0.68$ with open mouth examinations 30.5% increase was (P<0.05). Conclusion Tumor SUV on the changes that had an increase in open mouth during inspection, the normal tongue and lymph node, but there was no significant difference in the change slightly. It is also one open mouth PET / CT scan will provide improved image to all patients with tongue cancer, but it could be confirmed that similar overall through the blind test, or tumor size changes and showing a high resolution image. It can be the perfect alternative method for problems that occur when the close mouth Open mouth PET / CT scan, but is believed to be through the open mouth to observe the boundary of overlapping or tumor of the oral cavity other structures a little more clearly. Tongue cancer patients how to recommend that the shooting further open mouth PET / CT.