정상 성인 무증상 흡연자 , 당뇨병 환자에서 99mTc-DTPA 폐제거율의 측정

김인주,김성장,김용기,김윤성,이민기,박순규 ( In Ju Kim,Seong Jang Kim,Yong Ki Kim,Yun Seong Kim,Min Ki Lee,Soon Kew Park ) 대한핵의학회 1998 핵의학 분자영상 Vol.32 No.3

Purpose: We measured pulmonary epithelial permeability by Tc-DTPA radioaerosol clearance in patients with diabetes and correlated with the presence of microangiopathy to understand the pathophysiology of pulmonary microangiopathy and evaluate Tc-DTPA radioaerosol clearance as a diagnostic test to assess pulmonary microangiopathy. Materials and Methods: We performed ' Tc-DTPA radioaerosol scan in 10 normal subjects, 10 asym-ptomatic smokers, 20 diabetic patients without history of smoking (10 with microangiopathy, 10 without microangiopathy). Tc-DTPA clearance half-time (T1/2) was calculated, then compared with the result of chest radiography and pulmonary function test. Results: Chest radiography and pulmonary function test were normal in all subjects. There were no significant difference of clinical or laboratory characteristics between these groups except age. The diabetic patients with micraangiopathy were significantly older (p<0.05). The T1/2of normal subjects and asyrnptomatic smokers were significantly different (65.2+23.7min vs 39.6+9.8min, p<0.05). For diabetic patients with microangiopathy, the T, was 90 5+46.5min and significantly delayed when compared with those of normals and asymptomatic smokers (p<0.05). However, the T1/2of diabetic patients without microangiopathy, 70.0+12.7 min, was not significantly different from those of normals or asyrnptomatic smokers (p>0.05). No significant correlation was found between the T1/2and spirometric parameters including DLcc>, FVC, FEV>, FEV(/FVC (%) and FEF)5-75g in all subjects, and between the T1/2 and duration of diabetes in diabetic patients. Conclusion: Eventhough the influence of age cant be excluded, delayed Tc-DTPA clearance half-time (T1/2)in diabetic patients with microangiopathy indicates decreased pulmonary cspillary permeability as one of the pathophysiologic results of pulmonary microangiopaththy. Further studies are needed in larger number of age matched control and diabetic patients to evaluate the diagnostic efficacy. (Korean J Nucl Med 1998;32:266-75)

하악 자연치열에 대합되는 상악 임플란트 전악 수복 증례

김인주,박종희,박주미,송광엽,안승근,서재민,Kim, In-Ju,Park, Jong-Hee,Park, Ju-Mi,Song, Kwang-Yeob,Ahn, Seung-Geun,Seo, Jae-Min 대한치과보철학회 2015 대한치과보철학회지 Vol.53 No.1

치주질환에 의해 수평적, 수직적 골흡수를 보이는 환자에게 전악 임플란트 고정성 보철수복 치료를 계획한 경우에는 저작 기능, 심미, 발음 등을 고려한 임플란트 식립이 필요하다. 이를 위해 철저한 임상적, 방사선학적 진단이 필요하며 광범위한 골이식과 연조직 이식술이 요구되기도 한다. 아직까지도 골이식한 상악에 대한 적절한 임플란트 식립 개수, 하부구조물 분할 여부 및 상부 구조물의 유지 방법 등에 대한 명확한 지침이 마련되어 있지 않기 때문에 진단과정에서 이를 고려한 검사가 요구된다. 본 증례에서는 치주질환 병력이 있는 환자에서 상, 하악 다수 치아 발거 및 치주 치료 후, 골이식 및 연조직 이식을 동반한 다수 임플란트 식립과 하악 자연 치열에 대합되는 상악 임플란트 전악 보철수복을 통하여 기능적, 심미적으로 만족할 만한 결과를 얻었기에 이를 보고하고자 한다. When an implant-supported maxillary full-arch fixed prosthesis is planned for patients with the horizontal and vertical bone resorption induced by periodontal disease, it is necessary to consider the masticatory function, esthetics and phonetics when placing implants. For this reason, thorough clinical and radiological diagnosis is necessary. Extensive bone and soft tissue grafting may be required as well. Since there is no clear guideline for proper number of implants, segment or splinting of substructure and method of retaining prosthesis, these should be considered during diagnostic process. This clinical report describes a patient who has experienced several tooth extractions and periodontal treatment due to severe periodontitis on maxilla and mandible. With bone and soft tissue graft before dental implant placement, the patient have satisfactory result in esthetic and functional aspect with the implant-supported maxillary full-arch fixed prosthesis opposing mandibular natural dentition.

건강의 새로운 화두, 대사증후군- 대사증후군을 진단하는 기준들

김인주,Kim, In-Ju 사단법인 한국당뇨협회 2005 당뇨 Vol.188 No.-

대사증후군이란 비만, 당대사이상, 고혈압 및 이상지질혈증과 같은 다양한 대사이상이 한 개인에게 중복되어 나타나는 상태를 지칭하는 것이다. 그러므로 대사증후군도 생활 습관병 중의 하나라고 생각할 수 있다. 대사증후군을 막을 수 있는 가장 경제적이면서도 효육적인 방법으로는 적절한 운동과 식사요법이라는 건강한 생활습관을 유지하여 적정한 체중을 유지하는 기초적인 건강수칙을 실천하는 것이 무엇보다 중요하다.

Gorynebacterium glutamicum 에서의 glutamate 계 아미노산 생합성의 유전적 조절

김인주(In - Ju Kim),민경희(Kyung Hee Min),이세배(Sae Bae Lee) 한국미생물생명공학회 1986 한국미생물·생명공학회지 Vol.14 No.5

적응적 인지적 정서조절전략과 삶의 만족간의 관계에서 삶의 의미와 외상후 성장의 조절된 매개 효과- 대리외상을 경험한 성폭력지원센터 실무자들을 대상으로

김인주(In-Ju kim),김도연(Doh-Yun kim) 한국발달지원학회 2020 발달지원연구 Vol.9 No.3

본 연구는 업무상 대리외상을 경험하였다고 보고한 성폭력지원센터 실무자들을 대상으로 적응적 인지적 정서조절 전략과 삶의 만족간의 관계에서 삶의 의미의 매개효과와 외상후 성장의 조절된 매개 효과를 확인하고자 하였다. 변인들간의 관계를 구체적으로 알아보기 위하여 회귀모형 및 커널회귀 모형 분석을 실시하였다. 연구 결과들은 다음과 같다. 첫째, 대리외상을 경험한 대상자 집단에서 적응적 인지적 정서조절 전략, 삶의 의미, 외상후 성장, 삶의 만족간에 상호 유의한 상관관계가 있었다. 둘째, 적응적 인지적 정서조절 전략과 삶의 만족간의 관계에서 삶의 의미의 매개 효과와 외상후 성장의 조절된 매개 모형이 확인되었다. 즉, 적응적인 인지적 정서조절 전략이 삶의 의미를 통하여 삶의 만족에 미치는 매개효과는 외상후 성장 수준에 따라 달라지는 조건적 매개 효과가 확인됨에 따라 외상후 성장의 조절 기능을 제시할 수 있었다. 이러한 결과를 바탕으로 본 연구의 의의 및 대리외상 경험 이후 삶의 만족을 높이는 프로그램 개발 필요성에 대해논의하였다. The purpose of this study was to examine the mediation effect of meaning in life and moderated mediating effect of posttraumatic growth through meaning in life on the relationship between adaptive cognitive emotion regulation strategies and life satisfaction among sexual violence trauma center workers who experienced vicarious trauma. The main findings were as follows. First, the mediation effect of meaning in life and moderated mediating effect of posttraumatic growth in the relationship between adaptive cognitive emotion regulation strategies and life satisfaction were confirmed. That is, the mediating effect of the adaptive cognitive emotion regulation strategies on life satisfaction through the meaning of life varies depending on the posttraumatic growth level. Based on these results, implications and suggestions for future treatment are discussed.

나환자의 Clofazimine에 의한 피부변화의 관찰

김인주(In Ju Kim),정상립(Sang Lip Chung) 대한피부과학회 1983 大韓皮膚科學會誌 Vol.21 No.5

Clofazimine (Lamprene or B668) is a phenazine congener that is used in leprosy, and the patients treated with the drug may develop red discoloration, dark brown pigmentation and ichthyotic skin. The authors observed 181 leprosy patients who had developecl discoloration, pigmentation and ichthyotic skin during clofazimine therapy, as well as disappearance of the pigmentation after stop of it. The results are summarized as follows: 1) Reddish discoloration was most frequently observed 2 weeks after beginning treatment in 66 patients (50. 4%), which showed earlier in the higher dosage grow up, 2) Dark brown pigmentation was iviost frequently observed 4 weeks after beginning treatment in 64 patients (48. 9%), which showed earlier in the higher dosage group. R) For histopathological evaluation of pigmentation, various ataining rnethods were used. On unstained frozen sections, yellow brown crystals were scattered in the dermis of both discolored and pigmented skin, and in H R E stain pigments, melanin were niarkedly increased in the epidermal basal layer and a, faint yellow brown. ghost was seen in dermis of pigmented skin. With fat stains using oil-red-0 and Sudan III, reddish amorphous materials were scattered in and around the cytoplasm of the macrophages c>f the pigmented skin. 4) Ichthyotic skin was observed in 97 patients, and most frequently 2 and R months after beginning treatment in 26 patients (26. 8%), but it was never observec1 in 34 of all patients in spite of a continuous intake of the drug for more than a. year. -countinue-

GMA 위보기 및 수직자세 초층용접 최적조건 선정에 관한 실험적 연구

김지선,김인주,김일수,Kim, Ji-Sun,Kim, In-Ju,Kim, Ill-Soo 대한용접접합학회 2012 대한용접·접합학회지 Vol.30 No.6

Due to increase in demand of stable and long pipelines in natural gas industry, wide range of researches are being performed on automation welding to improved welding quality with respect to weld process parameters in real time measurement. In particular, the coupling between the pipe manufacturing process and location of the weld seam, the measured size of the gap that exists in the weld position and the weld angle depending on whether the movement of molten weld. This is due to absence of controlling welding penetration position, depending on the required size of the angle of the setting. In addition, the optimum welding conditions must be considered while selecting, the correlation between these variables and the systematic correlation has not yet been identified. Therefore, in most welded pipe root-pass weld solely depends on the experience of workers in relation to secure a stable weld quality. In this study, automation welding system is implemented to select a suitable root-pass STT (Surface Tension Transfer) welding method using the optimal welding conditions. To successfully accomplish this objective, there were various welding conditions used for welding experiment to confirm that the assessment required for construction through the pipe and automatic welding process is proposed to optimize this plan.

갑상선유두상암에서 종양의 크기에 대한 수술 전 초음파검사소견과 수술 후 병리조직검사소견의 비교

이현민 ( Hyun-min Lee ),김민우 ( Min-woo Kim ),임윤성 ( Yoon-sung Lim ),이진춘 ( Jin-choon Lee ),이병주 ( Byung-joo Lee ),왕수건 ( Soo-geun Wang ),김상수 ( Sang-su Kim ),김인주 ( In-ju Kim ),김용기 ( Yong-ki Kim ) 대한갑상선학회 2009 International Journal of Thyroidology Vol.2 No.2

Background and Objectives: Size of thyroid tumor is one of important parameters in making decision for the surgical extent of thyroid resection and necessity of lymph node dissection in papillary thyroid carcinoma (PTC). Although tumor size by pathologic finding is important to evaluate the prognosis of patient with PTC, the decision of surgical extent depend on the preoperative ultrasonographic tumor size. The purpose of this study is to compare primary tumor size between preoperative ultrasonographic and pathologic results in PTC. Materials and Methods: From March 2008 to February 2009, 105 patients (22 males, 83 females) with PTC who were undergone ultrasonographic examination within 3 months before operation were reviewed retrospectively. We measured the longest diameter of tumor in both ultrasonographic findings and pathogic results and were compared with size according to tumor nature (solid vs mixed types) in both examination. Data was analyzed by linear regression analysis. Results: Mean preoperative ultrasonographic tumor size were greater than pathologic size. Decreasing rate of tumor size are 15.7% in all cases and 7.7% in the solid type. The tumor size by preoperative ultrasonosgraphy are strong correlation with size of pathologic results in all cases (n=105, γ²= 0.602, p<0.05) and solid type (n=97, γ²=0.706, p<0.05). But there is no significant correlation with size measured by ultrasonographic and pathologic findings in mixed type (n=8, γ²=208, p>0.05). Conclusion: There are some size discrepancy between preoperative ultrasonographic findings and pathologic results, especially mixed type. The decision of surgical extent based on preoperative ultrasonographic finding would be considered its size discrepancy.

활동성 폐결핵의 판정에서 99mTc-MIBI 의 유용성

김용기(Yong Ki Kim),김인주(In Ju Kim),이효진(Hyo Jin Lee),전두수(Doo Soo Cheon),유석동(Seok Dong Yoo),이민기(Min Ki Lee),박순규(Soon Kew Park),김성장(Seong Jang Kim) 대한핵의학회 1998 핵의학 분자영상 Vol.32 No.1

N/A The use of radiopharmaceuticals in evaluation of pulmonary tuberculosis may help to resolve difficult diagnostic problems such as discordance between sputum examinations and chest roentgenographic findings. We investigated the usefulness of 99mTc-methoxyisobutylisonitrile(MIBI) scintigraphy in the detection of active pulmonary tuberculosis. Forty-six patients with suspected active pulmonary tuberculosis were studied with sputum smear of AFB, sputum AFB culture, chest X-ray and MIBI scan. MIBI image was obtained 15 and 60 min after intravenous injection of 370MBq(10mCi) 99mTc-MIBI. In 16 patients of them Ga scans were performed in addition to MIBI scan. Repeated MIBI scans were done in 7 patients with active pulmonary tuberculosis after 4∼6 months of antituberculous chemotherapy. Thirty-two patients were confirmed as active tuberculosis by sputum culture. Sensitivity of MIBI scan to active tuberculosis was 87.5%(28/32) and MIBI findings were negative in all of 14 patients with inactive disease. Focal uptake of MIBI was dense in the area that was strongly suggested active tuberculous lesions by chest roentgenogram. There was no discordance between MIBI and Ga image in 16 patients. But the uptake areas of Ga images were broader than that of MIBI images. After 4∼6 months of antituberculous treatment all repeated MIBI scans revealed negative findings except 1 patient with persistent active pulmonary tuberculosis due to drug resistance. MIBI scan could be used in the detection of active pulmonary tuberculosis as a useful noninvasive diagnostic tool.

인슐린 비의존형 당뇨병 환자의 혈청 C - peptide 농도와 혈당조절의 임상적 평가에 관한 연구

배상균(Sang Kyun Bae),김인주(In Ju Kim),박현(Hyun Park),유석동(Seuck Dong Yoo),김정완(Jung Wan Kim),김용기(Yong Ki Kim),김동수(Dong Soo Kim) 대한내과학회 1987 대한내과학회지 Vol.33 No.6

N/A To evaluate the clinical characteristics and relationships between the values of serum glucose, C-peptide and body mass index (BMI) in non-insulin dependent DM, we had investigated 28 cases of NIDDM who had admitted in Pusan National University Hospital from Mar. 1985 to Aug. 1986. The patients were divided into two groups according to postprandial serum insulin, C-peptide levels and therapeutic modalities: The following results were observed; 1) The BMI of the patients with postprandial value more than 30μU/ml for insulin (group I1) and 3.6ng/ml for C-peptide (group C1) was higher and Hb A1-C was lower than that of the patients with less values (group I2, C2), respectively. 2) Comparing the data in the group who were treated with oral hypoglycemics (glibenclamide), mean fasting and postprandial serum C-peptide levels were higher in responders than non responders, and the C-peptide/BMI scores were 15.8±5.5 vs 16.5±6.4 (p>0.05), C-peptide/Glucose score, 1.81±0.47 vs 1.02±0.37 (p<0.025); and Glucose/BMI score, 861±121 vs 1162±105 (p<0.01) in responders and non-responders, respectively. 3) Comparing the data in the group who were treated with insulin, the C-peptide/Glucose score were 13.5±4.3 vs 14.8±6.1 (p>0.05); C-peptide/Glucose score, 1.48±0.48 vs 0.88±0.35 (p<0.01); and C-peptide/BMI score, 945±227 vs 1588±139 (p<0.005) in responders and non-responders, respectively. 4) The responders in both group who were treated with oral hypoglycemics or insulin were characterized by C-peptide/Glucose score greater than 1 and C-peptide/BMI score less than 900 and the non-responders by C-peptide/Glucose score less than 1, and Glucose/BMI score greater than 900. These simple calculated indexes are practical and may serve for evaluating the glycemic control and determining the therapeutic modalities.