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Lung Transplantation for Chronic Humidifier Disinfectant-Associated Lung Injury
김원영,So-Woon Kim,Kyung-Wook Jo,Sae Hoon Choi,,Hyung Ryul Kim,Yong Hee Kim,김동관,Seung-Il Park,홍상범 대한중환자의학회 2016 Acute and Critical Care Vol.31 No.2
In the spring of 2011, a cluster of lung injuries caused by humidifier disinfectant (HD) usage were reported in Korea. Many patients required mechanical ventilation, extracorporeal membrane oxygenation, and even lung transplantation (LTPL). However, the longterm course of HD-associated lung injury remains unclear because the majority of survivors recovered normal lung function. Here we report a 33-year-old woman who underwent LTPL approximately four years after severe HD-associated lung injury. The patient was initially admitted to the intensive care unit and was supported by a high-flow nasal cannula. Although she had been discharged, she was recurrently admitted to our hospital due to progressive lung fibrosis and a persistent decline in lung function. Finally, sequential double LTPL was successfully performed, and the patient’s clinical and radiological findings showed significant improvement. Therefore, we conclude that LTPL can be a therapeutic option for patients with chronic inhalation injury.
석고 모형재와 고무인상재의 젖음성이 지르코니아 코핑의 변연적합도에 미치는 영향
김원영,정인성,전병욱,Kim, Won-Young,Chung, In-Sung,Jeon, Byung-Wook 대한치과기공학회 2016 대한치과기공학회지 Vol.38 No.4
Purpose: This study examined the effect of wettability of gypsum materials and rubber impression material on the marginal fitness of zirconia copings. Methods: Three commercially available gypsum materials(Fugirock EP, Snow Rock, Tuff Rock) and three zirconia blocks(iJAM Emerald, LUXEN Smile block, ICE Zirkon transluzent) were studied. The zirconia copings were fabricated by using dental CAD/CAM system. Contact angles on the impression materials were measured with contact angle measuring device. Silicone replica method was used to measure the marginal fitness and cutting was performed on the bucco-lingual and mesio-distal sides. It were observed with a stereomicroscope at °ø40 magnification. The data were statistically analyzed with One-way ANOVA. Results: Mean values of contact angles were $58.3{\pm}0.7^{\circ}$ for Tuff Rock, $77.5{\pm}0.5^{\circ}$ for Fugirock EP and $87.8{\pm}0.5^{\circ}$ for Snow Rock and the difference between them was statistically significant(p<0.05). The smallest values of marginal fitness for the JF groups were $30.7{\pm}3.0{\mu}m$ for bucco-lingual direction, $29.3{\pm}3.0{\mu}m$ for mesio-distal direction. One-way ANOVA showed statistically significant difference between groups for marginal fitness(p<0.05). Conclusion: Tuff rock gypsum material had superior wettability to others. The mean marginal fitness of the Tuff rock gypsum material group were significantly better than other groups. Thus they can be also expected to show clinically satisfactory marginal fitness.
김원영,이영석,이재완,서창호,Kim, Won-Young,Lee, Young-Seok,Lee, Jae-Wan,Seo, Chang-Ho 한국정보통신학회 2008 한국정보통신학회논문지 Vol.12 No.3
유비쿼터스 환경에서의 컴퓨팅 기기들은 초경량 컴퓨팅 환경으로서 사용자들이 컴퓨터의 존재를 인지할 수 없도록 사용자 신체나 주변 환경에 내장되며, 크기가 작고, 적은 기능을 가진 많은 컴퓨터를 여러 곳에 분포하여 네트워크로 통신한다. 초경량 컴퓨팅 환경에서는 사용자들에게 서비스를 제공하기 위해 사용자의 정보를 교환하는 일이 많으며, 사용자의 정보를 보호하기 위해서는 보안 기술이 반드시 포함되어야 한다. 본 논문에서는 초경량 컴퓨팅 환경에서 표준화 된 보안 서비스를 제공하는 초경량 환경을 위한 보안 서비스 지원을 위한 API를 연구하고 설계한다. 초경량 환경의 보안 서비스 지원을 위한 API는 일반적인 컴퓨팅 환경에서와 같이 데이터 암호화, 데이터 인증, 키 관리 등의 보안 서비스를 제공하며, 초경 량 컴퓨팅 환경에 맞는 RC5와 SHA1 알고리즘 사용, 효율적인 메모리 관리를 위해 각 서비스를 라이브러리화하여 필요시마다 라이브러리를 할당/해제하는 등의 초경량 컴퓨팅 환경의 문제점을 해결할 수 있도록 설계, 구현한다. Computers used fer light-weight computing environments are considerably limited in resources and performance running in ubiquitous environment. Because of the limited resources, it is difficult to apply existing security technologies to the light-weight computers. In this paper, light-weight security software is implemented using RC-5 encryption and SHA-1 authentication algorithm which is appropriate for light-weight computing environments. The design of components based on security software of a light-weight computer application and the test-bed for security software are presented. The simulation verifies the correctness of the security software. The architecture of the light-weight and reconfigurable security software for light-weight computer applications is proposed. The proposed security software is small size and provides reconfigurable security library based on the light-weight component and the software manager that configures software platform is loaded with the library at the time it is needed.
USN환경에서 2단계 사용자 인증을 이용한 침입 방지 방안
김원영,이영석,김선진,방효찬,Kim, Won-Young,Lee, Young-Seok,Kim, Sun-Jin,Bang, Hyo-Chan 한국정보통신학회 2014 한국정보통신학회논문지 Vol.18 No.1
본 논문에서는 이기종 무선 센서들이 포함된 USN 환경에 적합한 보안성과 확장성을 갖춘 사용자 인증 방식을 갖는 침입 방지 방안을 제안한다. 본 연구에서 제안하는 사용자 인증 방식은 공용키 암호 방식과 비밀키 암호 방식을 모두 사용하고, 두 방법의 장점들을 활용하는 인증방식이다. 본 논문에서는 제안한 방식이 기존의 비밀 키 암호 기반 방식에 비해 보안성과 확장성이 뛰어나고, 전력 요구량은 더 적으며, 기존의 공용 키 암호 기반 방법들에 비해 에너지 효율이 더 높은 장점을 갖는 것을 시뮬레이션 결과로 보여준다. USN heterogeneous wireless sensors embedded in the environment with appropriate security and scalability with user authentication method is proposed intrusion prevention. In this study, the proposed user authentication and secret key cryptography, public key cryptography is used for both, to take advantage of the strengths of the two methods is authentication. In this paper, the proposed scheme the secret key of the existing security than password-based system performance, highly scalable, power demand is less, and the public-key cryptography based on the existing methods, a higher energy efficiency compared to the benefits that the simulation results with shown as.
Relationship between low hemoglobin levels and mortality in patients with septic shock
김원영,Sung Min Jung,Youn-Jung Kim,Seung Mok Ryoo 대한중환자의학회 2019 Acute and Critical Care Vol.34 No.2
Background: Hemoglobin levels are a critical parameter for oxygen delivery in patients with shock. On comparing target hemoglobin levels upon transfusion initiation, the correlation between the severity of decrease in hemoglobin levels and patient outcomes remains unclear. We evaluated the association between initial hemoglobin levels and mortality in patients with septic shock treated with protocol-driven resuscitation bundle therapy at an emergency department. Methods: Data of adult patients diagnosed with septic shock between June 2012 and December 2016 were extracted from a prospectively compiled septic shock registry at a single academic medical center. Patients were classified into four groups according to initial hemoglobin levels: ≥ 9.0 g/dl, 8.0−8.9 g/dl, 7.0−7.9 g/dl, and < 7.0 g/dl. The primary endpoint was 90-day mortality. Results: In total, 2,265 patients (male, 58.3%; median age, 70.0 years [interquartile range, 60 to 78 years]) with septic shock were included. For the four groups, 90-day mortality rates were as follows: 29.1%, 43.0%, 46.5%, and 46.9% for ≥ 9.0 g/dl (n = 1,808), 8.0−8.9 g/dl (n = 217), 7.0−7.9 g/dl (n = 135), and < 7.0 g/dl (n = 105), respectively (P < 0.001). Multivariate logistic regression showed that initial hemoglobin levels were an independent factor associated with 90-day mortality and mortality proportionally increased with decreasing hemoglobin levels (odds ratio [OR], 1.88; 95% confidence interval [CI], 1.36 to 2.61 for 8.0−8.9 g/dl; OR, 1.97;95% CI, 1.31 to 2.95 for 7.0–7.9 g/dl; and OR, 2.35; 95% CI, 1.52 to 3.63 for < 7.0 g/dl). Conclusions: Low hemoglobin levels ( < 9.0 g/dl) were observed in approximately 20% of patients with septic shock, and the severity of decrease in these levels correlated with mortality.